Structural correlates of COMT Val158Met polymorphism in childhood ADHD: a voxel-based morphometry study

References

• American Psychiatric Association. 2013. Diagnostic and statistical manual of mental disorders, 5th ed. Washington, DC: American Psychiatric Press.
   Google Scholar
• Aron AR. 2011. From reactive to proactive and selective control: developing a richer model for stopping inappropriate responses. Biol Psychiatry 69:e55–68.
   PubMed Web of Science ®Google Scholar
• Ashburner J, Friston KJ. 2000. Voxel-based morphometry – the methods. NeuroImage 11:805–821.
   PubMed Web of Science ®Google Scholar
• Batalla A, Soriano-Mas C, Torrens M, Crippa JA, Bhattacharyya S, Blanco-Hinojo L, et al. 2013. Modulation of brain structure by catechol O-methyltransferase ValMet polymorphism in chronic cannabis users. Eur Neuropsychopharmacol 23(Supplement 1): S78–79.
   Google Scholar
• Bertocci B, Miggiano V, Daprada M, Dembic Z, Lahm HW, Malherbe P. 1991. Human catechol-O-methyltransferase cloning and expression of the membrane-associated form. Proc Natl Acad Sci USA 88:1416–1420.
   PubMed Web of Science ®Google Scholar
• Bilder RM, Volavka J, Lachman HM, Grace AA. 2004. The catechol-O-methyltransferase polymorphism: relations to the tonic-phasic dopamine hypothesis and neuropsychiatric phenotypes. Neuropsychopharmacology 29:1943–1961.
   PubMed Web of Science ®Google Scholar
• Caspi A, Langley K, Milne B, Moffitt TE, O’Donovan M, Owen MJ, et al. 2008. A replicated molecular genetic basis for subtyping antisocial behaviour in children with attention- deficit/hyperactivity disorder. Arch Gen Psychiatry 65:203–210.
   PubMed Web of Science ®Google Scholar
• Castellanos FX, Sonuga-Barke EJS, Milham MP, Tannock R. 2006. Characterizing cognition in ADHD: beyond executive dysfunction. Trends Cogn Sci 10:117–123.
   PubMed Web of Science ®Google Scholar
• Cerasa A, Gioia MC, Labate A, Liguori M, Lanza P, Quattrone A. 2008. Impact of catechol-O-methyltransferase Val(108/158)Met genotype on hippocampal and prefrontal gray matter volume. Neuroreport 19:405–408.
   PubMed Web of Science ®Google Scholar
• Chakos MH, Lieberman JA, Bilder RM, Borenstein M, Lerner G, Bogerts B, et al. 1994. Increase in caudate nuclei volumes of first-episode schizophrenic patients taking antipsychotic drugs. Am J Psychiatry 151:1430–1436.
   PubMed Web of Science ®Google Scholar
• Chambers CD, Garavan H, Bellgrove MA. 2009. Insights into the neural basis of response inhibition from cognitive and clinical neuroscience. Neurosci Biobehav Rev 33:631–646.
   PubMed Web of Science ®Google Scholar
• Chen JS, Lipska BK, Halim N, Ma QD, Matsumoto M, Melhem S, et al. 2004. Functional analysis of genetic variation in catechol-o-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain. Am J Hum Genet 75:807–821.
   PubMed Web of Science ®Google Scholar
• Craddock N, Owen MJ, O'Donovan MC. 2006. The catechol-O-methyl transferase (COMT) gene as a candidate for psychiatric phenotypes: evidence and lessons. Mol Psychiatry 11: 446–458.
   PubMed Web of Science ®Google Scholar
• Cubillo A, Halari R, Ecker C, Giampietro V, Taylor E, Rubia K. 2010. Reduced activation and inter-regional functional connectivity of fronto-striatal networks in adults with childhood Attention-Deficit Hyperactivity Disorder (ADHD) and persisting symptoms during tasks of motor inhibition and cognitive switching. J Psychiatr Res 44:629–639.
   PubMed Web of Science ®Google Scholar
• Dodge KA. 2009. Mechanisms of gene-environment interaction effects in the development of conduct disorder. Perspect Psychol Sci 4:408–414.
   PubMedGoogle Scholar
• Ducharme S, Hudziak JJ, Botteron KN, Ganjavi H, Lepage C, Collins DL, et al. 2011. Right anterior cingulate cortical thickness and bilateral striatal volume correlate with child behavior checklist aggressive behavior scores in healthy children. Biol Psychiatry 70:283–290.
   PubMed Web of Science ®Google Scholar
• DuPaul GJ, Power TJ, Anastopoulos AD, Reid R. 1998. ADHD Rating scale-IV: checklists, norms, and clinical interpretation. New York: The Guilford Press.
   Google Scholar
• Durston S, Fossella JA, Casey BJ, Pol HEH, Galvan A, Schnack HG, et al. 2005. Differential effects of DRD4 and DAT1 genotype on fronto-striatal gray matter volumes in a sample of subjects with attention deficit hyperactivity disorder, their unaffected siblings, and controls. Molec Psychiatry 10:678–685.
   PubMed Web of Science ®Google Scholar
• Durston S, Pol HEH, Schnack HG, Buitelaar JK, Steenhuis MP, Minderaa RB, et al. 2004. Magnetic resonance imaging of boys with attention-deficit/hyperactivity disorder and their unaffected siblings. J Am Acad Child Adolesc Psychiatry 43:332–340.
   PubMed Web of Science ®Google Scholar
• Egeland M, Zhang XQ, Millan MJ, Mocaer E, Svenningsson P. 2012. Pharmacological or genetic blockade of the dopamine D3 receptor increases cell proliferation in the hippocampus of adult mice. J Neurochem 123:811–823.
   PubMed Web of Science ®Google Scholar
• Ehrlich S, Morrow EM, Roffman JL, Wallace SR, Naylor M, Bockholt HJ, et al. 2010. The COMT Val108/158Met polymorphism and medial temporal lobe volumetry in patients with schizophrenia and healthy adults. NeuroImage 53:992–1000.
   PubMed Web of Science ®Google Scholar
• Endicott J, Spitzer RL. 1978. A diagnostic interview. The schedule for affective disorders and schizophrenia. Arch Gen Psychiatry 35:837–844.
   PubMed Web of Science ®Google Scholar
• Frodl T, Skokauskas N. 2012. Meta-analysis of structural MRI studies in children and adults with attention deficit hyperactivity disorder indicates treatment effects. Acta Psych Scand 125:114–126.
   PubMed Web of Science ®Google Scholar
• Furukawa E, Bado P, Tripp G, Mattos P, Wickens JR, Bramati IE, et al. 2014. Abnormal striatal BOLD responses to reward anticipation and reward delivery in ADHD. Plos One 9.
   Web of Science ®Google Scholar
• Gizer IR, Ficks C, Waldman ID. 2009. Candidate gene studies of ADHD: a meta-analytic review. Hum Genet 126:51–90.
   PubMed Web of Science ®Google Scholar
• Glenn AL, Raine A, Yaralian PS, Yang YL. 2010. Increased volume of the striatum in psychopathic individuals. Biol Psychiatry 67:52–58.
   PubMed Web of Science ®Google Scholar
• Glenn AL, Yang YL. 2012. The potential role of the striatum in antisocial behavior and psychopathy. Biol Psychiatry 72: 817–822.
   PubMed Web of Science ®Google Scholar
• Gogos JA, Morgan M, Luine V, Santha M, Ogawa S, Pfaff D, et al. 1998. Catechol-O-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior. Proc Natl Acad Sci USA 95:9991–9996.
   PubMed Web of Science ®Google Scholar
• Grahn JA, Parkinson JA, Owen AM. 2008. The cognitive functions of the caudate nucleus. Progr Neurobiol 86:141–155.
   PubMed Web of Science ®Google Scholar
• Hamshere ML, Langley K, Martin J, Agha SS, Stergiakouli E, Anney RJL, et al. 2013. High loading of polygenic risk for ADHD in children with comorbid aggression. Am J Psychiatry 170:909–916.
   PubMed Web of Science ®Google Scholar
• Honea R, Verchinski BA, Pezawas L, Kolachana BS, Callicott JH, Mattay VS, et al. 2009. Impact of interacting functional variants in COMT on regional gray matter volume in human brain. NeuroImage 45:44–51.
   PubMed Web of Science ®Google Scholar
• Jensen J, McIntosh AR, Crawley AP, Mikulis DJ, Remington G, Kapur S. 2003. Direct activation of the ventral striatum in anticipation of aversive stimuli. Neuron 40:1251–1257.
   PubMed Web of Science ®Google Scholar
• Karoum F, Chrapusta SJ, Egan MF. 1994. 3-Methoxytyramine is the major metabolite of released dopamine in the rat frontal-cortex – reassessment of the effects of antipsychotics on the dynamics of dopamine release and metabolism in the frontal-cortex, nucleus-accumbens, and striatum by a simple 2-pool model. J Neurochem 63:972–979.
   PubMed Web of Science ®Google Scholar
• Klein RG, Mannuzza S, Olazagasti MAR, Roizen E, Hutchison JA, Lashua EC, et al. 2012. Clinical and functional outcome of childhood attention-deficit/hyperactivity disorder 33 years later. Arch Gen Psychiatry 69:1295–1303.
   PubMed Web of Science ®Google Scholar
• Kurth F, Luders E, Gaser, C. 2010. VBM8-toolbox manual. Available at: http://dbm.neuro.uni-jena.de/vbm8/VBM8-Manual.pdf.
   Google Scholar
• Laatikainen LM, Sharp T, Harrison PJ, Tunbridge EM. 2013. Sexually dimorphic effects of catechol-O-methyltransferase (COMT) inhibition on dopamine metabolism in multiple brain regions. Plos One 8.
   Web of Science ®Google Scholar
• Lachman HM. 2008. Does COMT val(158)met affect behavioral phenotypes: yes, no, maybe? Neuropsychopharmacology 33: 3027–3029.
   PubMed Web of Science ®Google Scholar
• Lachman HM, Papolos DF, Saito T, Yu YM, Szumlanski CL, Weinshilboum RM. 1996. Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders. Pharmacogenetics 6:243–250.
   PubMedGoogle Scholar
• Langley K, Heron J, O’Donovan MC, Owen MJ, Thapar A. 2010. Genotype link with extreme antisocial behavior the contribution of cognitive pathways. Arch Gen Psychiatry 67:1317–1323.
   PubMed Web of Science ®Google Scholar
• Mahone EM, Crocetti D, Ranta ME, Gaddis A, Cataldo M, Slifer KJ, et al. 2011. A preliminary neuroimaging study of preschool children with ADHD. Clin Neuropsychol 25:1009–1028.
   PubMed Web of Science ®Google Scholar
• Maldjian JA, Laurienti PJ, Kraft RA, Burdette JH. 2003. An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets. NeuroImage 19:1233–1239.
   PubMed Web of Science ®Google Scholar
• Mannisto PT, Kaakkola S. 1999. Catechol-O-methyltransferase (COMT): biochemistry, molecular biology, pharmacology, and clinical efficacy of the new selective COMT inhibitors. Pharmacol Rev 51:593–628.
   PubMed Web of Science ®Google Scholar
• Masuda M, Tsunoda M, Imai K. 2003. High-performance liquid chromatography-fluorescent assay of catechol-O-methyltransferase activity in rat brain. Anal Bioanal Chem 376:1069–1073.
   PubMed Web of Science ®Google Scholar
• Mechelli A, Tognin S, McGuire PK, Prata D, Sartori G, Fusar-Poli P, et al. 2009. Genetic vulnerability to affective psychopathology in childhood: a combined voxel-based morphometry and functional magnetic resonance imaging study. Biol Psychiatry 66:231–237.
   PubMed Web of Science ®Google Scholar
• Monuteaux MC, Biederman J, Doyle AE, Mick E, Faraone SV. 2009. Genetic risk for conduct disorder symptom subtypes in an ADHD sample: specificity to aggressive symptoms. J Am Acad Child Adolesc Psychiatry 48:757–764.
   PubMed Web of Science ®Google Scholar
• Nakao T, Radua J, Rubia K, Mataix-Cols D. 2011. Gray matter volume abnormalities in ADHD: voxel-based meta-analysis exploring the effects of age and stimulant medication. Am J Psychiatry 168:1154–1163.
   PubMed Web of Science ®Google Scholar
• Navari S, Dazzan P. 2009. Do antipsychotic drugs affect brain structure? A systematic and critical review of MRI findings. Psychol Med 39:1763–1777.
   PubMed Web of Science ®Google Scholar
• Nikolas MA, Burt SA. 2010. Genetic and environmental influences on ADHD symptom dimensions of inattention and hyperactivity: a meta-analysis. J Abnorm Psychol 119:1–17.
   PubMed Web of Science ®Google Scholar
• Paloyelis Y, Mehta MA, Faraone SV, Asherson P, Kuntsi J. 2012. Striatal sensitivity during reward processing in attention deficit hyperactivity disorder (ADHD). J Am Acad Child Adolesc Psychiatry 51:722–732.
   PubMed Web of Science ®Google Scholar
• Polanczyk G, de Lima MS, Horta BL, Biederman J, Rohde LA. 2007. The worldwide prevalence of ADHD: a systematic review and metaregression analysis. Am J Psychiatry 164:942–948.
   PubMed Web of Science ®Google Scholar
• Qian QJ, Liu J, Wang YF, Yang L, Guan LL, Faraone SV. 2009. Attention deficit hyperactivity disorder comorbid oppositional defiant disorder and its predominately inattentive type: evidence for an association with COMT but not MAOA in a Chinese sample. Behav Brain Functions 5.
   PubMed Web of Science ®Google Scholar
• Rhee SH, Willcutt EG, Hartman CA, Pennington BF, DeFries JC. 2008. Test of alternative hypotheses explaining the comorbidity between attention-deficit/hyperactivity disorder and conduct disorder. J Abnorm Child Psychol 36:29–40.
   PubMed Web of Science ®Google Scholar
• Rubia K, Cubillo A, Smith AB, Woolley J, Heyman I, Brammer MJ. 2010. Disorder-specific dysfunction in right inferior prefrontal cortex during two inhibition tasks in boys with attention deficit hyperactivity disorder compared to boys with obsessive-compulsive disorder. Hum Brain Mapp 31:287–299.
   PubMed Web of Science ®Google Scholar
• Salatino-Oliveira A, Genro JP, Guimaraes AP, Chazan R, Zeni C, Schmitz M, et al. 2012. Cathechol-O-methyltransferase Val(158)Met polymorphism is associated with disruptive behavior disorders among children and adolescents with ADHD. J Neur Trans 119:729–733.
   Google Scholar
• Scheres A, Milham MP, Knutson B, Castellanos FX. 2007. Ventral striatal hyporesponsiveness during reward anticipation in attention-deficit/hyperactivity disorder. Biol Psychiatry 61:720–724.
   PubMed Web of Science ®Google Scholar
• Schiffer B, Muller BW, Scherbaum N, Hodgins S, Forsting M, Wiltfang J, et al. 2011. Disentangling structural brain alterations associated with violent behavior from those associated with substance use disorders. Arch Gen Psychiatry 68:1039–1049.
   PubMed Web of Science ®Google Scholar
• Shaw P, Eckstrand K, Sharp W, Blumenthal J, Lerch JP, Greenstein D, et al. 2007. Attention-deficit/hyperactivity disorder is characterized by a delay in cortical maturation. Proc Natl Acad Sci USA 104:19649–19654.
   PubMed Web of Science ®Google Scholar
• Shaw P, Wallace GL, Addington A, Evans A, Rapoport J, Giedd JN. 2009. Effects of the Val(158)Met catechol-O-methyltransferase polymorphism on cortical structure in children and adolescents. Molec Psychiatry 14:348–349.
   PubMed Web of Science ®Google Scholar
• Sjowall D, Roth L, Lindqvist S, Thorell LB. 2013. Multiple deficits in ADHD: executive dysfunction, delay aversion, reaction time variability, and emotional deficits. J Child Psychol Psychiatry 54:619–627.
   PubMed Web of Science ®Google Scholar
• Soliva JC, Fauquet J, Bielsa A, Rovira M, Carmona S, Ramos-Quiroga JA, et al. 2010. Quantitative MR analysis of caudate abnormalities in pediatric ADHD: proposal for a diagnostic test. Psychiatry Res: Neuroimag 182:238–243.
   PubMed Web of Science ®Google Scholar
• Sonuga-Barke EJS, Halperin JM. 2010. Developmental phenotypes and causal pathways in attention deficit/hyperactivity disorder: potential targets for early intervention? J Child Psychol Psychiatry 51:368–389.
   PubMed Web of Science ®Google Scholar
• Sowell ER, Thompson PM, Welcome SE, Henkenius AL, Toga AW, Peterson BS. 2003. Cortical abnormalities in children and adolescents with attention-deficit hyperactivity disorder. Lancet 362:1699–1707.
   PubMed Web of Science ®Google Scholar
• Sterzer P, Stadler C, Poustka F, Kleinschmidt A. 2007. A structural neural deficit in adolescents with conduct disorder and its association with lack of empathy. NeuroImage 37: 335–342.
   PubMed Web of Science ®Google Scholar
• Storebø OJ, Simonsen E. 2013. The Association Between ADHD and Antisocial personality disorder (ASPD): a review. J Atten Disord.
   Google Scholar
• Thapar A, Langley K, Fowler T, Rice F, Turic D, Whittinger N, et al. 2005. Catechol O-methyltransferase gene variant and birth weight predict early-onset antisocial behavior in children with attention-deficit/hyperactivity disorder. Arch Gen Psychiatry 62:1275–1278.
   PubMed Web of Science ®Google Scholar
• Tunbridge EM, Harrison PJ, Weinberger DR. 2006. Catechol-o-methyltransferase, cognition, and psychosis: Val(158)Met and beyond. Biol Psychiatry 60:141–151.
   PubMed Web of Science ®Google Scholar
• Valera EM, Faraone SV, Murray KE, Seidman LJ. 2007. Meta-analysis of structural imaging findings in attention-deficit/hyperactivity disorder. Biol Psychiatry 61:1361–1369.
   PubMed Web of Science ®Google Scholar
• Villablanca JR. 2010. Why do we have a caudate nucleus? Acta Neurobiol Exp 70:95–105.
   PubMed Web of Science ®Google Scholar
• Wechsler D. 1999. Wechsler abbreviated scale of intelligence. San Antonio, TX: The Psychological Corporation.
   Google Scholar
• Wilke M, Holland SK, Altaye M, Gaser C. 2008. Template-O-Matic: a toolbox for creating customized pediatric templates. NeuroImage 41:903–913.
   PubMed Web of Science ®Google Scholar