Prediction of psychosis using neural oscillations and machine learning in neuroleptic-naïve at-risk patients

References

• Amminger GP, Edwards J, Brewer WJ, Harrigan S, McGorry PD. 2002. Duration of untreated psychosis and cognitive deterioration in first-episode schizophrenia. Schizophr Res 54:223–230.
   PubMed Web of Science ®Google Scholar
• Assmus A, Marshall JC, Ritzl A, Noth J, Zilles K, Fink GR. 2003. Left inferior parietal cortex integrates time and space during collision judgments. Neuroimage 20 Suppl 1:S82–S88.
   PubMed Web of Science ®Google Scholar
• Babiloni C, Carducci F, Lizio R, Vecchio F, Baglieri A, Bernardini S, et al. 2013. Resting state cortical electroencephalographic rhythms are related to gray matter volume in subjects with mild cognitive impairment and Alzheimer's disease. Hum Brain Mapp 34:1427–1446.
   PubMed Web of Science ®Google Scholar
• Bischl L., Lang M, Richter J, Bossek J, Judt L, Kuehn T, et al. 2015. mlr: Machine Learning in R. R package version 2.4. https://cran.r-project.org/web/packages/mlr/
   Google Scholar
• Borgwardt SJ, McGuire PK, Aston J, Gschwandtner U, Plflueger MO, Stieglitz R-D, et al. 2008. Reductions in frontal, temporal and parietal volume associated with the onset of psychosis. Schizophrenia Research 106:108–114.
   PubMed Web of Science ®Google Scholar
• Canuet L, Ishii R, Pascual-Marqui RD, Iwase M, Kurimoto R, Aoki Y, et al. 2011. Resting-state EEG source localization and functional connectivity in schizophrenia-like psychosis of epilepsy. PloS One 6:e27863.
   PubMed Web of Science ®Google Scholar
• Canuet L, Tellado I, Couceiro V, Fraile C, Fernandez-Novoa L, Ishii R, et al. 2012. Resting-state network disruption and APOE genotype in Alzheimer's disease: a lagged functional connectivity study. PLoS One 7:e46289.
   PubMed Web of Science ®Google Scholar
• Caspers S, Schleicher A, Bacha-Trams M, Palomero-Gallagher N, Amunts K, Zilles K. 2013. Organization of the human inferior parietal lobule based on receptor architectonics. Cereb Cortex 23:615–628.
   PubMed Web of Science ®Google Scholar
• Cavanna AE, Trimble MR. 2006. The precuneus: a review of its functional anatomy and behavioural correlates. Brain 129:564–583.
   PubMed Web of Science ®Google Scholar
• Centorrino F, Price BH, Tuttle M, Bahk W-M, Hennen J, Albert MJ, et al. 2002. EEG abnormalities during treatment with typical and atypical antipsychotics. Am J Psychiatry 159:109–115.
   PubMed Web of Science ®Google Scholar
• Dua S, Du X. 2011. Data mining and machine learning in cybersecurity. Boca Raton: CRC press.
   Google Scholar
• Frederikse M, Lu A, Aylward E, Barta P, Sharma T, Pearlson G. 2000. Sex differences in inferior parietal lobule volume in schizophrenia. Am J Psychiatry 157:422–427.
   PubMed Web of Science ®Google Scholar
• Fusar-Poli P, Bonoldi I, Yung AR, Borgwardt S, Kempton MJ, Valmaggia L, et al. 2012. Predicting psychosis: meta-analysis of transition outcomes in individuals at high clinical risk. Archives of General Psychiatry 69:220–229.
   PubMed Web of Science ®Google Scholar
• Fusar-Poli P, Borgwardt S, Crescini A, Deste G, Kempton MJ, Lawrie S, et al. 2011a. Neuroanatomy of vulnerability to psychosis: a voxel-based meta-analysis. Neurosci Biobehav Rev 35:1175–1185.
   PubMed Web of Science ®Google Scholar
• Fusar-Poli P, Crossley N, Woolley J, Carletti F, Perez-Iglesias R, Broome M, et al. 2011b. Gray matter alterations related to P300 abnormalities in subjects at high risk for psychosis: Longitudinal MRI-EEG study. NeuroImage 55:320–328.
   PubMed Web of Science ®Google Scholar
• Gusnard DA, Raichle ME. 2001. Searching for a baseline: functional imaging and the resting human brain. Nature Reviews Neuroscience 2:685–694.
   PubMed Web of Science ®Google Scholar
• Helleputte T. 2013. LiblineaR: Linear Predictive Models Based On The Liblinear C/C++ Library. R package version 1.80-7 ed.
   Google Scholar
• Herrmann CS, Demiralp T. 2005. Human EEG gamma oscillations in neuropsychiatric disorders. Clin Neurophysiol 116:2719–2733.
   PubMed Web of Science ®Google Scholar
• Insel TR. 2010. Rethinking schizophrenia. Nature 468:187–193.
   PubMed Web of Science ®Google Scholar
• Kasai K, Shenton ME, Salisbury DF, Hirayasu Y, Lee CU, Ciszewski AA, et al. 2003. Progressive decrease of left superior temporal gyrus gray matter volume in patients with first-episode schizophrenia. Am J Psychiatry 160:156–164.
   PubMed Web of Science ®Google Scholar
• Kopell N, Ermentrout GB, Whittington MA, Traub RD. 2000. Gamma rhythms and beta rhythms have different synchronization properties. Proc Natl Acad Sci USA 97:1867–1872.
   PubMed Web of Science ®Google Scholar
• Koutsouleris N, Davatzikos C, Bottlender R, Patschurek-Kliche K, Scheuerecker J, Decker P, et al. 2012. Early recognition and disease prediction in the at-risk mental states for psychosis using neurocognitive pattern classification. Schizophr Bull 38:1200–1215.
   PubMed Web of Science ®Google Scholar
• Koutsouleris N, Riecher-Rössler A, Meisenzahl EM, Smieskova R, Studerus E, Kambeitz-Ilankovic L, et al. 2014. Detecting the Psychosis Prodrome Across High-risk Populations Using Neuroanatomical Biomarkers. Schizophr Bull.
   Web of Science ®Google Scholar
• Kuhn S, Gallinat J. 2013. Resting-state brain activity in schizophrenia and major depression: a quantitative meta-analysis. Schizophr Bull 39:358–365.
   PubMed Web of Science ®Google Scholar
• Lee KH, Williams LM, Breakspear M, Gordon E. 2003. Synchronous gamma activity: a review and contribution to an integrative neuroscience model of schizophrenia. Brain Res Brain Res Rev 41:57–78.
   PubMed Web of Science ®Google Scholar
• Liu C, Che D, Liu X, Song Y. 2013. Applications of machine learning in genomics and systems biology. Computational and Mathematical Methods in Medicine 2013:
   Web of Science ®Google Scholar
• Lukoff D, Nuechterlein K, Ventura J. 1986. Manual for the expanded brief psychiatric rating scale. Schizophr Bull 12:594–602.
   Web of Science ®Google Scholar
• McGorry PD, Edwards J, Mihalopoulos C, Harrigan SM, Jackson HJ. 1996. EPPIC: an evolving system of early detection and optimal management. Schizophr Bull 22:305–326.
   PubMed Web of Science ®Google Scholar
• Michel CM, Murray MM, Lantz G, Gonzalez S, Spinelli L, Grave de Peralta R. 2004. EEG source imaging. Clin Neurophysiol 115:2195–2222.
   PubMed Web of Science ®Google Scholar
• Morris R, Griffiths O, Le Pelley ME, Weickert TW. 2012. Attention to irrelevant cues is related to positive symptoms in schizophrenia. Schizophrenia Bulletin:sbr192
   Google Scholar
• Moscarelli M. 1994. Health and economic evaluation in schizophrenia: implications for health policies. Acta Psychiatr Scand Suppl 382:84–88.
   PubMedGoogle Scholar
• Mulert C, Jäger L, Schmitt R, Bussfeld P, Pogarell O, Möller H-J, et al. 2004. Integration of fMRI and simultaneous EEG: towards a comprehensive understanding of localization and time-course of brain activity in target detection. Neuroimage 22:83–94.
   PubMed Web of Science ®Google Scholar
• Pascual-Marqui RD. 2007. Discrete, 3D distributed, linear imaging methods of electric neuronal activity. Part 1: exact, zero error localization. arXiv preprint arXiv:0710.3341.
   Google Scholar
• Pascual-Marqui RD, Lehmann D, Koukkou M, Kochi K, Anderer P, Saletu B, et al. 2011. Assessing interactions in the brain with exact low-resolution electromagnetic tomography. Philos Trans a Math Phys Eng Sci 369:3768–3784.
   PubMed Web of Science ®Google Scholar
• Pascual-Marqui RD, Michel CM, Lehmann D. 1994. Low resolution electromagnetic tomography: a new method for localizing electrical activity in the brain. Int J Psychophysiol 18:49–65.
   PubMed Web of Science ®Google Scholar
• R Core Team. 2014. R: A language and environment for statistical computing.
   Google Scholar
• Ramyead A, Kometer M, Studerus E, Koranyi S, Ittig S, Gschwandtner U, et al. 2014. Aberrant Current Source-Density and Lagged Phase Synchronization of Neural Oscillations as Markers for Emerging Psychosis. Schizophr Bull.
   PubMed Web of Science ®Google Scholar
• Riecher-Rössler A, Aston J, Ventura J, Merlo M, Borgwardt S, Gschwandtner U, et al. 2008. [The Basel Screening Instrument for Psychosis (BSIP): development, structure, reliability and validity]. Fortschr Neurol Psychiatr 76:207–216.
   PubMed Web of Science ®Google Scholar
• Riecher‐Rössler A, Gschwandtner U, Aston J, Borgwardt S, Drewe M, Fuhr P, et al. 2007. The Basel early-detection-of-psychosis (FEPSY)-study-design and preliminary results. Acta Psychiatrica Scandinavica 115:114–125.
   PubMed Web of Science ®Google Scholar
• Riecher-Rössler A, Gschwandtner U, Borgwardt S, Aston J, Pflueger M, Rössler W. 2006. Early detection and treatment of schizophrenia: how early? Acta Psychiatr Scand 113 Suppl:73–80.
   PubMed Web of Science ®Google Scholar
• Riecher-Rössler A, Pflueger MO, Aston J, Borgwardt SJ, Brewer WJ, Gschwandtner U, et al. 2009. Efficacy of using cognitive status in predicting psychosis: a 7-year follow-up. Biol Psychiatry 66:1023–1030.
   PubMed Web of Science ®Google Scholar
• Ruhrmann S, Schultze-Lutter F, Schmidt SJ, Kaiser N, Klosterkötter J. 2014. Prediction and prevention of psychosis: current progress and future tasks. Eur Arch Psychiatry Clin Neurosci 264 Suppl 1:9–16.
   Web of Science ®Google Scholar
• Salisbury DF, Shenton ME, Sherwood AR, et al. 1998. FIrst-episode schizophrenic psychosis differs from first-episode affective psychosis and controls in p300 amplitude over left temporal lobe. Archives of General Psychiatry 55:173–180.
   PubMed Web of Science ®Google Scholar
• Shah JL, Tandon N, Keshavan MS. 2013. Psychosis prediction and clinical utility in familial high-risk studies: selective review, synthesis, and implications for early detection and intervention. Early Intervention in Psychiatry 7:345–360.
   PubMed Web of Science ®Google Scholar
• Shapleske J, Rossell SL, Chitnis XA, Suckling J, Simmons A, Bullmore ET, et al. 2002. A computational morphometric MRI study of schizophrenia: effects of hallucinations. Cereb. Cortex12:1331–1341.
   PubMed Web of Science ®Google Scholar
• Simon AE, Borgwardt S, Riecher-Rössler A, Velthorst E, de Haan L, Fusar-Poli P. 2013. Moving beyond transition outcomes: meta-analysis of remission rates in individuals at high clinical risk for psychosis. Psychiatry Res 209:266–272.
   PubMed Web of Science ®Google Scholar
• Stafford MR, Jackson H, Mayo-Wilson E, Morrison AP, Kendall T. 2013. Early interventions to prevent psychosis: systematic review and meta-analysis. BMJ: British Medical Journal 346:
   Web of Science ®Google Scholar
• Steyerberg EW. 2009. Clinical prediction models a practical approach to development, validation, and updating. New York, NY: Springer.
   Google Scholar
• Tenke CE, Kayser J, Manna CG, Fekri S, Kroppmann CJ, Schaller JD, et al. 2011. Current source density measures of electroencephalographic alpha predict antidepressant treatment response. Biol Psychiatry 70:388–394.
   PubMed Web of Science ®Google Scholar
• Tibshirani R. 1996. Regression shrinkage and selection via the lasso. Journal of the Royal Statistical Society. Series B (Methodological) 267–288.
   Web of Science ®Google Scholar
• Torrey EF. 2007. Schizophrenia and the inferior parietal lobule. Schizophr Res 97:215–225.
   PubMed Web of Science ®Google Scholar
• Uhlhaas PJ, Singer W. 2010. Abnormal neural oscillations and synchrony in schizophrenia. Nat Rev Neurosci 11:100–113.
   PubMed Web of Science ®Google Scholar
• Uhlhaas PJ, Singer W. 2013. High-frequency oscillations and the neurobiology of schizophrenia. Dialogues Clin Neurosci 15:301–313.
   PubMedGoogle Scholar
• van Tricht MJ, Nieman DH, Koelman JH, van der Meer JN, Bour LJ, de Haan L, et al. 2010. Reduced parietal P300 amplitude is associated with an increased risk for a first psychotic episode. Biol Psychiatry 68:642–648.
   PubMed Web of Science ®Google Scholar
• van Tricht MJ, Ruhrmann S, Arns M, Müller R, Bodatsch M, Velthorst E, et al. 2014. Can quantitative EEG measures predict clinical outcome in subjects at Clinical High Risk for psychosis? A prospective multicenter study. Schizophrenia Research 153:42–47.
   PubMed Web of Science ®Google Scholar
• Velligan D, Prihoda T, Dennehy E, Biggs M, Shores-Wilson K, Crismon ML, et al. 2005. Brief psychiatric rating scale expanded version: How do new items affect factor structure? Psychiatry Research 135:217–228.
   PubMed Web of Science ®Google Scholar
• Ventura J, Green MF, Shaner A, Liberman RP. 1993. Training and quality assurance with the Brief Psychiatric Rating Scale:” the drift busters.”. International Journal of Methods in Psychiatric Research.
   Web of Science ®Google Scholar
• Wilke M, Kaufmann C, Grabner A, Putz B, Wetter TC, Auer DP. 2001. Gray matter-changes and correlates of disease severity in schizophrenia: a statistical parametric mapping study. Neuroimage 13:814–824.
   PubMed Web of Science ®Google Scholar
• Worrell GA, Lagerlund TD, Sharbrough FW, Brinkmann BH, Busacker NE, Cicora KM, et al. 2000. Localization of the epileptic focus by low-resolution electromagnetic tomography in patients with a lesion demonstrated by MRI. Brain Topography 12:273–282.
   PubMed Web of Science ®Google Scholar
• Yung AR, Phillips LJ, McGorry PD, McFarlane CA, Francey S, Harrigan S, et al. 1998. Prediction of psychosis. A step towards indicated prevention of schizophrenia. Br J Psychiatry 172:14–20.
   Web of Science ®Google Scholar
• Zumsteg D, Lozano AM, Wennberg RA. 2006. Depth electrode recorded cerebral responses with deep brain stimulation of the anterior thalamus for epilepsy. Clin Neurophysiol 117:1602–1609.
   PubMed Web of Science ®Google Scholar
• Zumsteg D, Wennberg R, Treyer V, Buck A, Wieser H. 2005. H2(15)O or 13NH3 PET and electromagnetic tomography (LORETA) during partial status epilepticus.. Neurology 65:1657–1660.
   PubMed Web of Science ®Google Scholar