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Original Article

Knowledge gaps in risk assessment of nanosilica in food: evaluation of the dissolution and toxicity of different forms of silica

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Pages 367-377 | Received 13 Dec 2011, Accepted 25 Jan 2012, Published online: 07 Mar 2012

References

  • Arienzo R, Bresciano E. 1968. Experimental shock caused by silica and its prevention with heparin. Boll Soc Ital Biol Sper 44(20):1685–1687; Italian.
  • Bosch A, Maier M, Morfeld P. 2011. Nanosilica? Clarifications are necessary! Nanotoxicology: [On line]. Available at: http://informahealthcare.com/doi/pdf/10.3109/17435390.2011.595837. (Accessed on 13 December 2011).
  • Cha KE, Myung H. 2007. Cytotoxic effects of nanoparticles assessed in vitro and in vivo. J Microbiol Biotechnol 17(9):1573–1578.
  • Cho M, Cho W, Choi M, Kim SJ, Han BS, Kim SH, 2009. The impact of size on tissue distribution and elimination by single intravenous injection of silica nanoparticles. Toxicol Lett 189:177–183.
  • Dan M, Wu P, Grulke EA, Graham UM, Unrine JM, Yokel RA. 2012. Ceria engineered nanomaterial distribution in and clearance from blood: size matters. Nanomedicine; 7 (1):95–110.
  • Dekkers S, Krystek P, Peters RJB, Lankveld DPK, Bokkers BGH, Van Hoeven-Arentzen PH, 2011. Presence and risks of nanosilica in food products. Nanotoxicology 5(3):393–405.
  • ECETOC. 2006. Synthetic Amorphous Silica. Joint Assessment of Commodity Chemicals (JACC) report No 51. Available at: http://www.ecetoc.org/jacc-reports. (Accessed on 3 May 2011).
  • European Food Safety Authority (EFSA). 2009. Scientific opinion of the panel on food additives and nutrient sources added to food on calcium silicate, silicon dioxide and silicic acid gel added for nutritional purposes to food supplements following a request from the European Commission. EFSA J 1132:1–24.
  • European Food Safety Authority (EFSA). 2011. Guidance on the risk assessment of the application of nanoscience and nanotechnologies in the food and feed chain. EFSA J 9(5):2140.
  • Expert group on vitamins and Minerals (EVM). 2003. Safe upper levels for vitamins and minerals, silicon & calcium UK Food Standards Agency. 2003. Available at: http://www.food.gov.uk/multimedia/pdfs/vitmin2003.pdf. (Accessed 7 April 2011).
  • Gye WE, Purdy WJ. 1922. The poisonous properties of colloidal silica II: The effects of repeated intravenous injection on rabbits; fibrosis of the liver. Br J Exp Pathol 3:86–94.
  • He Q, Zhang Z, Gao F, Li Y, Shi J. 2011. In vivo biodistribution and urinary excretion of mesoporous silica nanoparticles: effects of particle size and PEGylation. Small 7(2):271–280.
  • He X, Nie H, Wang K, Tan W, Wu X, Zhang P. 2008. In vivo study of biodistribution and urinary excretion of surface-modified silica nanoparticles. Anal Chem 80:9597–9603.
  • Kim JS, Yoon T-J, Yu KN, Kim BG, Park SJ, Kim HW, 2006. Toxicity and tissue distribution of magnetic nanoparticles in mice. Toxicol Sci 89(1):338–347.
  • Kumar R, Roy I, Ohulchanskky TY, Vathy LA, Bergey EJ, Sajjad M, 2010. In vivo biodistribution and clearance studies using multimodel ORMOSIL nanoparticles. ACS Nano 4(2):699–708.
  • Lin B, Xi Z, Zhang Y, Zhang H. 2008. Primary study on the hepatotoxicity and nephrotoxicity of rats induced by three kinds of nanomaterials. Wei Sheng Yan Jiu 37(6):651–3.
  • Liu T, Li L, Teng X, Huang X, Liu H, Chen D, 2011. Single and repeated dose toxicity of mesoporous hollow silica nanoparticles in intravenously exposed mice. Biomaterials 32:1657–1668.
  • Lu J, Liong M, Li Z, Zink JI, Tamanoi F. 2010. Biocompatibility, biodistribution, and drug-delivery efficiency of mesoporous silica nanoparticles for cancer therapy in animals. Small 6(16):1794–1805.
  • Lu X, Tian Y, Zhao Q, Jin T, Xiao S, Fan X. 2011. Integrated metabolomics analysis of the size-response relationship of silica nanoparticles-induced toxicity in mice. Nanotechnology. [Online]. Available at: http://iopscience.iop.org/0957-4484/22/5/055101/. (Accessed on 12 April 2011).
  • Nabeshi H, Yoshikawa T, Matsuyama K, Nakazato Y, Matsuo K, Arimori A, 2011. Systemic distribution, nuclear entry and cytotoxicity of amorphous nanosilica following topical application. Biomaterials 32:2713–2724.
  • Nishimori H, Kondoh M, Isoda K, Tsunoda S, Tsutsumi Y, Yagi K. 2009a. Silica nanoparticles as hepatotoxicants. Eur J Pharm Biopharm 72:496–501.
  • Nishimori H, Kondoh M, Isoda K, Tsunoda S, Tsutsumi Y, Yagi K. 2009b. Histological analysis of 70-nm silica particles-induced chronic toxicity in mice. Eur J Pharm Biopharm 72:626–29.
  • OECD Synthetic amorphous silica and silicates; Berlin, Germany. 2004. Available at: http://www.chem.unep.ch/irptc/sids/oecdsids/Silicates.pdf. (Accessed on 13 December 2011).
  • Powell JJ, Faria N, Thomas-McKay E, Pele LC. 2010. Origin and fate of dietary nanoparticles and microparticles in the gastrointestinal tract. J Autoimmun 34:J226–J233.
  • Powell JJ, Ainley CC, Harvey RSJ, Mason IM, Kendall MD, Sankey EA, 1996. Characterisation of inorganic microparticles in pigment cells of human gut associated lymphoid tissue. Gut 38:390–95.
  • So SJ, Jang IS, Han CS. 2008. Effect of micro/nano silica particle feeding for mice. J Nanosci Nanotechnol 8:5367–5371.
  • Swensson A, Glomme J, Bloom G. 1956. On the toxicity of silica particles. AMA Arch Ind Health 14(5):482–486.
  • Takizawa Y, Hirasawa F, Noritomi E, Aida M, Tsunoda H, Uesugi S. 1988. Oral ingestion of syloid to mice and rats and its chronic toxicity and carcinogenicity. Acta Medica et Biologica 36(1):27–56.
  • WHO. 1987. Principals for the safety assessment of food additives and contaminants in food. Wolrd Health Organization (WHO) Environmental Health Criteria 70.
  • Xie G, Sun J, Zhong G, Shi L, Zhang D. 2010. Biodistribution and toxicity of intravenously administered silica nanoparticles in mice. Arch Toxicol 84:183–190.
  • Yamashita K, Yoshioka Ym Higashisaka K, Mimura K, Morishita Y, Nozaki M, Yoshida T, 2011. Silica and titanium dioxide nanoparticles cause pregnancy complications in mice. Nat Nanotechnol 6:321–328.
  • Yang K, Wan J, Zhang S, Zhang Y, Lee ST, Liu Z. 2011. In vivo pharmacokinetics, long-term biodistribution, and toxicity of PEGylated graphene in mice. ACS Nano 5(1):516–522.

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