Acute pulmonary dose–responses to inhaled multi-walled carbon nanotubes

References

• Ago H, Kugler T, Cacialli F, Salaneck WR, Shaffer MSP, Windle AH, et al. 1999. Work functions and surface functional groups of multiwall carbon nanotubes. J Phys Chem B 103:8116–8121.
   Web of Science ®Google Scholar
• Aiso S, Kubota H, Umeda Y, Kasai T, Takaya M, Yamazaki K, et al. 2011. Translocation of intratracheally instilled multiwall carbon nanotubes to lung-associated lymph nodes in rats. Ind Health 49:215–220.
   PubMed Web of Science ®Google Scholar
• American Registry of Pathology. 1968. Manual of histologic staining methods of the armed forces institute of pathology. New York: McGraw-Hill.
   Google Scholar
• Blackford JA, Antonini JM, Castranova V, Dey RD. 1994. Intratracheal instillation of silica up-regulates inducible nitric-oxide synthase gene-expression and increases nitric-oxide production in alveolar macrophages and neutrophils. Am J Respir Cell Mol Biol 11:426–431.
   PubMed Web of Science ®Google Scholar
• Chen P, Wu X, Sun X, Lin J, Ji W, Tan KL. 1999. Electronic structure and optical limiting behavior of carbon nanotubes. Phys Rev Lett 82:2548–2551.
   Web of Science ®Google Scholar
• Choi HS, Ashitate Y, Lee JH, Kim SH, Matsui A, Insin N, et al. 2010. Rapid translocation of nanoparticles from the lung airspaces to the body. Nat Biotechnol 28:1300–1303.
   PubMed Web of Science ®Google Scholar
• Donaldson K, Aitken R, Tran L, Stone V, Duffin R, Forrest G, et al. 2006. Carbon nanotubes: a review of their properties in relation to pulmonary toxicology and workplace safety. Toxicol Sci 92:5–22.
   PubMed Web of Science ®Google Scholar
• Donaldson K, Tran CL. 2004. An introduction to the short-term toxicology of respirable industrial fibres. Mutat Res 553:5–9.
   PubMed Web of Science ®Google Scholar
• Elder A, Gelein R, Finkelstein JN, Driscoll KE, Harkema J, Oberdorster G. 2005. Effects of subchronically inhaled carbon black in three species. I. Retention kinetics, lung inflammation, and histopathology. Toxicol Sci 88:614–629.
   PubMed Web of Science ®Google Scholar
• Felten A, Bittencourt C, Pireaux JJ. 2006. Gold clusters on oxygen plasma functionalized carbon nanotubes: XPS and TEM studies. Nanotechnology 17:1954–1959.
   Web of Science ®Google Scholar
• Fenoglio I, Tomatis M, Lison D, Muller J, Fonseca A, Nagy JB, et al. 2006. Reactivity of carbon nanotubes: free radical generation or scavenging activity? Free Radic Biol Med 40:1227–1233.
   PubMed Web of Science ®Google Scholar
• Galer DM, Leung HW, Sussman RG, Trzos RJ. 1992. Scientific and practical considerations for the development of occupational exposure limits (Oels) for chemical-substances. Regul Toxicol Pharmacol 15:291–306.
   PubMed Web of Science ®Google Scholar
• Han JH, Lee EJ, Lee JH, So KP, Lee YH, Bae GN, et al. 2008. Monitoring multiwalled carbon nanotube exposure in carbon nanotube research facility. Inhal Toxicol 20:741–749.
   PubMed Web of Science ®Google Scholar
• Harmsen AG, Mason MJ, Muggenburg BA, Gillett NA, Jarpe MA, Bice DE. 1987. Migration of neutrophils from lung to tracheobronchial lymph node. J Leukoc Biol 41:95–103.
   PubMed Web of Science ®Google Scholar
• Harmsen AG, Muggenburg BA, Snipes MB, Bice DE. 1985. The role of macrophages in particle translocation from lungs to lymph nodes. Science 230(4731):1277–1280.
   PubMed Web of Science ®Google Scholar
• Henderson RF, Driscoll KE, Harkema JR, Lindenschmidt RC, Chang IY, Maples KR, et al. 1995. A comparison of the inflammatory responseof the lung to inhaled versus instilled partiocles in F344 rats. Fundam Appl Toxicol 24:183–197.
   PubMedGoogle Scholar
• Herbert RA, Leininger JR. 1999. Nose, larynx and trachea. In: Maronpot RR, Boorman GA, Gaul BW, editors. Pathology of the mouse. Vienna, IL: Cache River Press.
   Google Scholar
• Hoenerhoff MJ, Starost MF, Ward JM. 2006. Eosinophilic crystalline pneumonia as a major cause of death in 129S4/SvJae mice. Vet Pathol 43:682–688.
   PubMed Web of Science ®Google Scholar
• Hubbs AF, Goldsmith WT, Kashon ML, Frazer D, Mercer RR, Battelli LA, et al. 2008. Respiratory toxicologic pathology of inhaled diacetyl in sprague-dawley rats. Toxicol Pathol 36:330–344.
   PubMed Web of Science ®Google Scholar
• Kim YA, Hayashi T, Endo M, Kaburagi Y, Tsukada T, Shan J, et al. 2005. Synthesis and structural characterization of thin multi-walled carbon nanotubes with a partially facetted cross section by a floating reactant method. Carbon 43:2243–2250.
   Web of Science ®Google Scholar
• Lai HY, Rogers DF. 2010. Mucus hypersecretion in asthma: intracellular signalling pathways as targets for pharmacotherapy. Curr Opin Allergy Clin Immunol 10(1):67–76.
   PubMed Web of Science ®Google Scholar
• Lee JH, Lee S-B, Bae GN, Jeon KS, Yoon JU, Ji JH, et al. 2010. Exposure assessment of carbon nanotube manufacturing workplaces. Inhal Toxicol 22:369–381.
   PubMed Web of Science ®Google Scholar
• Li J-G, Li W-X, Xu J-Y, Cai X-Q, Liu R-L, Li Y-J, et al. 2007. Comparative study of pathological lesions induced by multiwalled carbon nanotubes in lungs of mice by intratracheal instillation and inhalation. Environ Toxicol 22:415–421.
   PubMed Web of Science ®Google Scholar
• Ma-Hock L, Treumann S, Strauss V, Brill S, Luizi F, Mertler M, et al. 2009. Inhalation toxicity of multiwall carbon nanotubes in rats exposed for 3 months. Toxicol Sci 112:468–481.
   PubMed Web of Science ®Google Scholar
• McKinney W, Chen B, Frazer D. 2009. Computer controlled multi-walled carbon nanotube inhalation exposure system. Inhal Toxicol 21:1053–1061.
   PubMed Web of Science ®Google Scholar
• Mercer RR, Hubbs AF, Scabilloni JF, Wang LY, Battelli LA, Friend S, et al. 2011. Pulmonary fibrotic response to aspiration of multi-walled carbon nanotubes. Part Fibre Toxicol 8:21.
   PubMed Web of Science ®Google Scholar
• Mercer RR, Hubbs AF, Scabilloni JF, Wang LY, Battelli LA, Schwegler-Berry D, et al. 2010. Distribution and persistence of pleural penetrations by multi-walled carbon nanotubes. Part Fibre Toxicol 7:28.
   PubMed Web of Science ®Google Scholar
• Mitchell LA, Gao J, Wal RV, Gigliotti A, Burchiel SW, McDonald JD. 2007. Pulmonary and systemic immune response to inhaled multiwalled carbon nanotubes. Toxicol Sci 100:203–214.
   PubMed Web of Science ®Google Scholar
• Mitchell LA, Lauer FT, Burchiel SW, McDonald JD. 2009. Mechanisms for how inhaled multiwalled carbon nanotubes suppress systemic immune function in mice. Nat Nanotechnol 4:451–456.
   PubMed Web of Science ®Google Scholar
• NIOSH. 1994. Method 7300. Elements by ICP (Nitric/Perchloric Acid Ashing). In: Eller PM, Cassinelli ME, editors. NIOSH manual of analytical methods. Cincinnati, Ohio: U.S. Department of Health and Human Services.
   Google Scholar
• NIOSH. 2010. NIOSH Current Intelligence Bulletin Occupational Exposure to Carbon Nanotubes and Nanofibers. http://www.cdc.gov/niosh/docket/review/docket161A/pdfs/carbonNanotubeCIB_PublicReviewOfDraft.pdf. Accessed on 12 July 2012.
   Google Scholar
• Oberdorster G, Maynard A, Donaldson K, Castranova V, Fitzpatrick J, Ausman K, Ilsi Research Foundation/Risk Science Institute Nanomaterial Toxicity, and Group Screening Working. 2005. Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy. Part Fibre Toxicol 2:8.
   PubMed Web of Science ®Google Scholar
• Pacurari M, Qian Y, Porter DW, Wolfarth M, Wan Y, Luo D, et al. 2011. Multi-walled carbon nanotube-induced gene expression in the mouse lung: association with lung pathology. Toxicol Appl Pharmacol 255:18–31.
   PubMed Web of Science ®Google Scholar
• Pauluhn J. 2010. Subchronic 13-week inhalation exposure of rats to multiwalled carbon nanotubes: toxic effects are determined by density of agglomerate structures, not fibrillar structures. Toxicol Sci 113:226–242.
   PubMed Web of Science ®Google Scholar
• Phalen RF. 1984. Basic morphology and physiology of the respiratory tract. In: Inhalation studies: foundattions and techniques. Boca Raton: CRC Press.
   Google Scholar
• Pinault M, Mayne-L'Hermite M, Reynaud C, Pichot V, Launois P, Ballutaud D. 2005. Growth of multiwalled carbon nanotubes during the initial stages of aerosol-assisted CCVD. Carbon 43:2968–2976.
   Web of Science ®Google Scholar
• Porter D, Sriram K, Wolfarth M, Jefferson A, Schwegler-Berry D, Andrew M, et al. 2008. A biocompatible medium for nanoparticle dispersion. Nanotoxicology 2:144–154.
   Web of Science ®Google Scholar
• Porter DW, Hubbs AF, Mercer RR, Wu NQ, Wolfarth MG, Sriram K, et al. 2010. Mouse pulmonary dose- and time course-responses induced by exposure to multi-walled carbon nanotubes. Toxicology 269:136–147.
   PubMed Web of Science ®Google Scholar
• Pulskamp K, Diabate S, Krug HF. 2007. Carbon nanotubes show no sign of acute toxicity but induce intracellular reactive oxygen species in dependence on contaminants. Toxicol Lett 168:58–74.
   PubMed Web of Science ®Google Scholar
• Rao GVS, Tinkle S, Weissman DN, Antonini JM, Kashon ML, Salmen R, et al. 2003. Efficacy of a technique for exposing the mouse lung to particles aspirated from the pharynx. J Toxicol Environ Health A 66:1441–1452.
   PubMed Web of Science ®Google Scholar
• Riviere JE. 2009. Pharmacokinetics of nanomaterials: an overview of carbon nanotubes, fullerenes and quantum dots. Wiley Interdiscip Rev Nanomed Nanobiotechnol 1:26–34.
   PubMed Web of Science ®Google Scholar
• Ryman-Rasmussen JP, Cesta MF, Brody AR, Shipley-Phillips JK, Everitt JI, Tewksbury EW, et al. 2009a. Inhaled carbon nanotubes reach the subpleural tissue in mice. Nat Nanotechnol 4:747–751.
   PubMed Web of Science ®Google Scholar
• Ryman-Rasmussen JP, Tewksbury EW, Moss OR, Cesta MF, Wong BA, Bonner JC. 2009b. Inhaled multiwalled carbon nanotubes potentiate airway fibrosis in murine allergic asthma. Am J Respir Cell Mol Biol 40:349–358.
   PubMed Web of Science ®Google Scholar
• Sargent LM, Hubbs AF, Young SH, Kashon ML, Dinu CZ, Salisbury JL, et al. 2012. Single-walled carbon nanotube-induced mitotic disruption. Mutat Res 745:28–37.
   PubMed Web of Science ®Google Scholar
• Shvedova AA, Kisin E, Murray AR, Johnson VJ, Gorelik O, Arepalli S, et al. 2008. Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis. Am J Physiol Lung CelL Mol Physiol 295:L552–L565.
   PubMed Web of Science ®Google Scholar
• Stankovich S, Piner RD, Chen XQ, Wu NQ, Nguyen ST, Ruoff RS. 2006. Stable aqueous dispersions of graphitic nanoplatelets via the reduction of exfoliated graphite oxide in the presence of poly (sodium 4-styrenesulfonate). J Mater Chem 16:155–158.
   Web of Science ®Google Scholar
• Stone KC, Mercer RR, Gehr P, Stockstill B, Crapo JD. 1992. Allometric realtionships of cell numbers and size in the mammalian lung. Am J Respir Cell Mol Biol 6:235–243.
   PubMed Web of Science ®Google Scholar
• Vallyathan V, Castranova V, Pack D, Leonard S, Shumaker J, Hubbs AF, et al. 1995. Freshly fractured quartz inahaltion leads to enhanced lung injury and inflammation – potential role of free-radicals. Am J Respir Crit Care Med 152:1003–1009.
   PubMed Web of Science ®Google Scholar
• Warheit DB. 2008. How meaningful are the results of nanotoxicity studies in the absence of adequate material characterization? Toxicol Sci 101:183–185.
   PubMed Web of Science ®Google Scholar
• Willard-Mack CL. 2006. Normal structure, function, and histology of lymph nodes. Toxicol Pathol 34:409–424.
   PubMed Web of Science ®Google Scholar
• Young HW, Williams OW, Chandra D, Bellinghausen LK, Perez G, Suarez A, et al. 2007. Central role of Muc5ac expression in mucous metaplasia and its regulation by conserved 5' elements. Am J Respir Cell Mol Biol 37:273–290.
   PubMed Web of Science ®Google Scholar
• Young JT. 1981. Histopathologic examination of the rat nasal cavity. Fundam Appl Toxicol 1:309–312.
   PubMedGoogle Scholar