Nano-titanium dioxide bioreactivity with human alveolar type-I-like epithelial cells: Investigating crystalline phase as a critical determinant

References

• Alam R, York J, Boyars M, Stafford S, Grant JA, Lee J, et al. 1996. Increased MCP-1, RANTES, and MIP-1alpha in bronchoalveolar lavage fluid of allergic asthmatic patients. Am J Respir Crit Care Med 153:1398–404
   PubMed Web of Science ®Google Scholar
• Baisch BL, Corson NM, Wade-Mercer P, Gelein R, Kennell AJ, Oberdörster G, Elder A. 2014. Equivalent titanium dioxide nanoparticle deposition by intratracheal instillation and whole body inhalation: the effect of dose rate on acute respiratory tract inflammation. Part Fibre Toxicol 11:5. doi: 10.1186/1743-8977-11-5
   PubMed Web of Science ®Google Scholar
• Belperio JA. 2001. Critical role for the chemokine MCP-1/CCR2 in the pathogenesis of bronchiolitis obliterans syndrome. J Clin Invest 108:547–56
   PubMed Web of Science ®Google Scholar
• Bohnsack JP, Assemi S, Miller JD, Furgeson DY. 2012. The primacy of physicochemical characterization of nanomaterials for reliable toxicity assessment: a review of the zebrafish nanotoxicology model. Methods Mol Biol 926:261–316
   PubMedGoogle Scholar
• Bradford MM. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248–54
   PubMed Web of Science ®Google Scholar
• Budd SL, Castilho RF, Nicholls DG. 1997. Mitochondrial membrane potential and hydroethidine-monitored superoxide generation in cultured cerebellar granule cells. FEBS Lett 415:21–4
   PubMed Web of Science ®Google Scholar
• Chen H-W, Su S-F, Chien C-T, Lin W-H, Yu S-L, Chou C-C, et al. 2006. Titanium dioxide nanoparticles induce emphysema-like lung injury in mice. FASEB J 20:2393–5
   PubMed Web of Science ®Google Scholar
• Ekstrand-Hammarström B, Akfur CM, Andersson PO, Lejon C, Österlund L, Bucht A. 2011. Human primary bronchial epithelial cells respond differently to titanium dioxide nanoparticles than the lung epithelial cell lines A549 and BEAS-2B. Nanotoxicology 6:623–34
   PubMed Web of Science ®Google Scholar
• Fink B, Laude K, McCann L, Doughan A, Harrison DG, Dikalov S. 2004. Detection of intracellular superoxide formation in endothelial cells and intact tissues using dihydroethidium and an HPLC-based assay. Am J Physiol Cell Physiol 287:C895–902
   PubMed Web of Science ®Google Scholar
• Gabay C. 2006. Interleukin-6 and chronic inflammation. Arthrit Res Ther 8:S3
   PubMed Web of Science ®Google Scholar
• Gilmour PS, Rahman I, Donaldson K, Macnee W. 2003. Histone acetylation regulates epithelial IL-8 release mediated by oxidative stress from environmental particles. Am J Physiol Lung Cell Mol Physiol 284:L533–40
   PubMed Web of Science ®Google Scholar
• Guadagnini R, Moreau K, Hussain S, Marano F, Boland S. 2013. Toxicity evaluation of engineered nanoparticles for medical applications using pulmonary epithelial cells. Nanotoxicology 1–8
   Web of Science ®Google Scholar
• Gurr J-R, Wang ASS, Chen C-H, Jan K-Y. 2005. Ultrafine titanium dioxide particles in the absence of photoactivation can induce oxidative damage to human bronchial epithelial cells. Toxicology 213:66–73
   PubMed Web of Science ®Google Scholar
• Heinemann A, Hartnell A, Stubbs VE, Murakami K, Soler D, LaRosa G, et al. 2000. Basophil responses to chemokines are regulated by both sequential and cooperative receptor signaling. J Immunol (Baltimore, MD, 1950) 165:7224–33
   PubMed Web of Science ®Google Scholar
• Hodge DR, Hurt EM, Farrar WL. 2005. The role of IL-6 and STAT3 in inflammation and cancer. Eur J Cancer (Oxford, England, 1990) 41:2502–12
   PubMed Web of Science ®Google Scholar
• Hristozov DR, Gottardo S, Critto A, Marcomini A. 2012. Risk assessment of engineered nanomaterials: a review of available data and approaches from a regulatory perspective. Nanotoxicology 6:880–98
   PubMed Web of Science ®Google Scholar
• Huang S, Chueh PJ, Lin Y-W, Shih T-S, Chuang S-M. 2009. Disturbed mitotic progression and genome segregation are involved in cell transformation mediated by nano-TiO2 long-term exposure. Toxicol Appl Pharmacol 241:182–94
   PubMed Web of Science ®Google Scholar
• Inoshima I, Kuwano K, Hamada N, Hagimoto N, Yoshimi M, Maeyama T, et al. 2003. Anti-monocyte chemoattractant protein-1 gene therapy attenuates pulmonary fibrosis in mice. Am J Physiol Lung Cell Mol Physiol 286:L1038–44
   Google Scholar
• Kaplanski G, Marin V, Montero-Julian F, Mantovani A, Farnarier C. 2003. IL-6: a regulator of the transition from neutrophil to monocyte recruitment during inflammation. Trends Immunol 24:25–9
   PubMed Web of Science ®Google Scholar
• Kemp SJ, Thorley AJ, Gorelik J, Seckl MJ, O'Hare MJ, Arcaro A, et al. 2008. Immortalization of human alveolar epithelial cells to investigate nanoparticle uptake. Am J Respir Cell Mol Biol 39:591–7
   PubMed Web of Science ®Google Scholar
• Kim I-S, Baek M, Choi S-J. 2010. Comparative cytotoxicity of Al2O3, CeO2, TiO2 and ZnO nanoparticles to human lung cells. J Nanosci Nanotechnol 10:3453–8
   PubMed Web of Science ®Google Scholar
• Kurihara T, Warr G, Loy J, Bravo R. 1997. Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor. J Exp Med 186:1757–62
   PubMed Web of Science ®Google Scholar
• Maynard RL, Donaldson K, Tetley TD. 2012. Type 1 pulmonary epithelial cells: a new compartment involved in the slow phase of particle clearance from alveoli. Nanotoxicology 7:350–1
   PubMed Web of Science ®Google Scholar
• Mundandhara SD, Becker S, Madden MC. 2006. Effects of diesel exhaust particles on human alveolar macrophage ability to secrete inflammatory mediators in response to lipopolysaccharide. Toxicol In Vitro 20:614–24
   PubMed Web of Science ®Google Scholar
• Nemmar A, Melghit K, Ali BH. 2008. The acute proinflammatory and prothrombotic effects of pulmonary exposure to rutile TiO2 nanorods in rats. Exp Biol Med 233:610–19
   PubMed Web of Science ®Google Scholar
• Oberdörster G, Oberdörster E, Oberdörster J. 2005. Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect 113:823–39
   PubMed Web of Science ®Google Scholar
• PEN. 2013. Consumer Products Inventory 2013. Available from: http://www.nanotechproject.org/cpi [online]
   Google Scholar
• Ruenraroengsak P, Novak P, Berhanu D, Thorley AJ, Valsami-Jones E, Gorelik J, et al. 2011. Respiratory epithelial cytotoxicity and membrane damage (holes) caused by amine-modified nanoparticles. Nanotoxicology 6:94–108
   PubMed Web of Science ®Google Scholar
• Salvi SS, Nordenhall C, Blomberg A, Rudell B, Pourazar J, Kelly FJ, et al. 2000. Acute exposure to diesel exhaust increases IL-8 and GRO-alpha production in healthy human airways. Am J Respir Crit Care Med 161:550–7
   PubMed Web of Science ®Google Scholar
• Sayes CMC, Wahi RR, Kurian PAP, Liu YY, West JLJ, Ausman KDK, et al. 2006. Correlating nanoscale titania structure with toxicity: a cytotoxicity and inflammatory response study with human dermal fibroblasts and human lung epithelial cells. Toxicol Sci 92:174–85
   PubMed Web of Science ®Google Scholar
• SCCS. 2013. Opinion on Titanium Dioxide (Nano Form) [online], ec.europa.eu. Available from: http://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_o_136.pdf
   Google Scholar
• Seiffert JM, Baradez M-O, Nischwitz V, Lekishvili T, Goenaga-Infante H, Marshall D. 2012. Dynamic monitoring of metal oxide nanoparticle toxicity by label free impedance sensing. Chem Res Toxicol 25:140–52
   PubMed Web of Science ®Google Scholar
• Simon-Deckers A, Gouget B, Mayne-L'Hermite M, Herlin-Boime N, Reynaud C, Carriere M. 2008. In vitro investigation of oxide nanoparticle and carbon nanotube toxicity and intracellular accumulation in A549 human pneumocytes. Toxicology 253:137–46
   PubMed Web of Science ®Google Scholar
• Soto K, Garza KM, Murr LE. 2007. Cytotoxic effects of aggregated nanomaterials. Acta Biomater 3:351–8
   PubMed Web of Science ®Google Scholar
• Thorley AJ, Grandolfo D, Lim E, Goldstraw P, Young A, Tetley TD. 2011. Innate immune responses to bacterial ligands in the peripheral human lung – role of alveolar epithelial TLR expression and signalling. PLoS One 6:e21827
   Google Scholar
• Tietze F. 1969. Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal Biochem 27:502–22
   PubMed Web of Science ®Google Scholar
• Valsami-Jones E, Berhanu D, Dybowska A, Misra S, Boccaccini AR, Tetley TD, et al. 2008. Nanomaterial synthesis and characterization for toxicological studies: TiO2 case study. Mineral Mag 72:515–19
   Web of Science ®Google Scholar
• van den Bogaard EHJ, Dailey LA, Thorley AJ, Tetley TD, Forbes B. 2009. Inflammatory response and barrier properties of a new alveolar type 1-like cell line (TT1). Pharm Res 26:1172–80
   PubMed Web of Science ®Google Scholar
• Vanwinkle BA, de Mesy Bentley KL, Malecki JM, Gunter KK, Evans IM, Elder A, et al. 2009. Nanoparticle (NP) uptake by type I alveolar epithelial cells and their oxidant stress response. Nanotoxicology 3:307–18
   PubMed Web of Science ®Google Scholar
• Wan R, Mo Y, Feng L, Chien S, Tollerud DJ, Zhang Q. 2012. DNA damage caused by metal nanoparticles: involvement of oxidative stress and activation of ATM. Chem Res Toxicol 25:1402–11
   PubMed Web of Science ®Google Scholar
• Warheit DB, Hoke RA, Finlay C, Donner EM, Reed KL, Sayes CM. 2007a. Development of a base set of toxicity tests using ultrafine TiO2 particles as a component of nanoparticle risk management. Toxicol Lett 171:99–110
   PubMed Web of Science ®Google Scholar
• Warheit DB, Webb TR, Reed KL, Frerichs S, Sayes CM. 2007b. Pulmonary toxicity study in rats with three forms of ultrafine-TiO2 particles: differential responses related to surface properties. Toxicology 230:90–104
   PubMed Web of Science ®Google Scholar
• Yu M, Zheng X, Witschi H, Pinkerton KE. 2002. The role of interleukin-6 in pulmonary inflammation and injury induced by exposure to environmental air pollutants. Toxicol Sci 68:488–97
   PubMed Web of Science ®Google Scholar