230
Views
3
CrossRef citations to date
0
Altmetric
Original Article

The MRI marker gene MagA attenuates the oxidative damage induced by iron overload in transgenic mice

, , , &
Pages 531-541 | Received 14 Apr 2015, Accepted 29 Aug 2015, Published online: 21 Oct 2015

References

  • Abdolahi M, Shahbazi-Gahrouei D, Laurent S, Sermeus C, Firozian F, Allen BJ, et al. 2013. Synthesis and in vitro evaluation of MR molecular imaging probes using J591 mAb-conjugated SPIONs for specific detection of prostate cancer. Contrast Media Mol Imaging 8:175–84
  • Bazylinski DA, Frankel RB. 2004. Magnetosome formation in prokaryotes. Nat Rev Microbiol 2:217–30
  • Bhirde A, Xie J, Swierczewska M, Chen X. 2011. Nanoparticles for cell labeling. Nanoscale 3:142–53
  • Brahler M, Georgieva R, Buske N, Muller A, Muller S, Pinkernelle J, et al. 2006. Magnetite-loaded carrier erythrocytes as contrast agents for magnetic resonance imaging. Nano Lett 6:2505–9
  • Bulte JW, Kraitchman DL. 2004. Iron oxide MR contrast agents for molecular and cellular imaging. NMR Biomed 17:484–99
  • Carrondo MA. 2003. Ferritins, iron uptake and storage from the bacterioferritin viewpoint. EMBO J 22:1959–68
  • Collard K, White D, Copplestone A. 2014. The influence of storage age on iron status, oxidative stress and antioxidant protection in paediatric packed cell units. Blood Transfus 12:210–19
  • Deans AE, Wadghiri YZ, Bernas LM, Yu X, Rutt BK, Turnbull DH. 2006. Cellular MRI contrast via coexpression of transferrin receptor and ferritin. Magn Reson Med 56:51–9
  • Dusek P, Dezortova M, Wuerfel J. 2013. Imaging of iron. Int Rev Neurobiol 110:195–239
  • Galy B, Ferring D, Minana B, Bell O, Janser HG, Muckenthaler M, et al. 2005. Altered body iron distribution and microcytosis in mice deficient in iron regulatory protein 2 (IRP2). Blood 106:2580–9
  • Genove G, Demarco U, Xu H, Goins WF, Ahrens ET. 2005. A new transgene reporter for in vivo magnetic resonance imaging. Nat Med 11:450–4
  • Goldhawk DE, Lemaire C, McCreary CR, McGirr R, Dhanvantari S, Thompson RT, et al. 2009. Magnetic resonance imaging of cells overexpressing MagA, an endogenous contrast agent for live cell imaging. Mol Imaging 8:129–39
  • James ML, Gambhir SS. 2012. A molecular imaging primer: modalities, imaging agents, and applications. Physiol Rev 92:897–965
  • Kim HS, Joo HJ, Woo JS, Choi YS, Choi SH, Kim H, Moon WK. 2013. In vivo magnetic resonance imaging of transgenic mice expressing human ferritin. Mol Imaging Biol 15:48–57
  • Li YF, Chen C. 2011. Fate and toxicity of metallic and metal-containing nanoparticles for biomedical applications. Small 7:2965–80
  • McDonald CI, Fraser JF, Coombes JS, Fung YL. 2014. Oxidative stress during extracorporeal circulation. Eur J Cardiothorac Surg 46:937–43
  • Melek FE, Baroncini LA, Repka JC, Nascimento CS, Precoma DB. 2012. Oxidative stress and inflammatory response increase during coronary artery bypass grafting with extracorporeal circulation. Rev Bras Cir Cardiovasc 27:61–5
  • Nakamura C, Burgess JG, Sode K, Matsunaga T. 1995. An iron-regulated gene, magA, encoding an iron transport protein of Magnetospirillum sp. strain AMB-1. J Biol Chem 270:28392–6
  • Pantopoulos K, Porwal SK, Tartakoff A, Devireddy L. 2012. Mechanisms of mammalian iron homeostasis. Biochemistry 51:5705–24
  • Recalcati S, Locati M, Marini A, Santambrogio P, Zaninotto F, De Pizzol M, et al. 2010. Differential regulation of iron homeostasis during human macrophage polarized activation. Eur J Immunol 40:824–35
  • Sanchez-Berrondo J, Mesa P, Ibarra A, Martinez-Jimenez MI, Blanco L, Mendez J, et al. 2012. Molecular architecture of a multifunctional MCM complex. Nucleic Acids Res 40:1366–80
  • Sengupta A, Quiaoit K, Thompson RT, Prato FS, Gelman N, Goldhawk DE. 2014a. Biophysical features of MagA expression in mammalian cells: implications for MRI contrast. Front Microbiol 5:29
  • Sengupta J, Ghosh S, Datta P, Gomes A. 2014b. Physiologically important metal nanoparticles and their toxicity. J Nanosci Nanotechnol 14:990–1006
  • Singh N, Manshian B, Jenkins GJ, Griffiths SM, Williams PM, Maffeis TG, et al. 2009. NanoGenotoxicology: the DNA damaging potential of engineered nanomaterials. Biomaterials 30:3891–914
  • Siponen MI, Adryanczyk G, Ginet N, Arnoux P, Pignol D. 2012. Magnetochrome: a c-type cytochrome domain specific to magnetotatic bacteria. Biochem Soc Trans 40:1319–23
  • Siponen MI, Legrand P, Widdrat M, Jones SR, Zhang WJ, Chang MC, et al. 2013. Structural insight into magnetochrome-mediated magnetite biomineralization. Nature 502:681–4
  • Skocaj M, Filipic M, Petkovic J, Novak S. 2011. Titanium dioxide in our everyday life: is it safe? Radiol Oncol 45:227–47
  • Uebe R, Henn V, Schuler D. 2012. The MagA protein of Magnetospirilla is not involved in bacterial magnetite biomineralization. J Bacteriol 194:1018–23
  • Vandsburger MH, Radoul M, Cohen B, Neeman M. 2013. MRI reporter genes: applications for imaging of cell survival, proliferation, migration and differentiation. NMR Biomed 26:872–84
  • Wang Y, Aker WG, Hwang HM, Yedjou CG, Yu H, Tchounwou PB. 2011. A study of the mechanism of in vitro cytotoxicity of metal oxide nanoparticles using catfish primary hepatocytes and human HepG2 cells. Sci Total Environ 409:4753–62
  • Xu J, Knutson MD, Carter CS, Leeuwenburgh C. 2008. Iron accumulation with age, oxidative stress and functional decline. PLoS One 3:e2865
  • Yoshida Y, Umeno A, Shichiri M. 2013. Lipid peroxidation biomarkers for evaluating oxidative stress and assessing antioxidant capacity in vivo. J Clin Biochem Nutr 52:9–16
  • Zamani A, Yousefi Mashouf R, Ebrahimzadeh Namvar AM, Alikhani MY. 2013. Detection of magA Gene in Klebsiella spp. Isolated from clinical samplesdetection of magA. Iran J Basic Med Sci 16:173–6
  • Zurkiya O, Chan AW, Hu X. 2008. MagA is sufficient for producing magnetic nanoparticles in mammalian cells, making it an MRI reporter. Magn Reson Med 59:1225–31

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.