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Original

Effect of local TGF-β1 and IGF-1 release on implant fixation: comparison with hydroxyapatite coating

A paired study in dogs

, , , &
Pages 499-504 | Accepted 05 May 2009, Published online: 26 Oct 2009

  • Capello WN, D'Antonio JA, Jaffe WL, Geesink RG, Manley MT, Feinberg JR. Hydroxyapatite-coated femoral components - 15-year minimum followup. Clin Orthop 2006, 453: 75–80
  • Dequeker J, Mohan S, Finkelman RD, Aerssens J, Baylink DJ. Generalized osteoarthritis associated with increased insulin-like growth factor types I and II and transforming growth factor beta in cortical bone from the iliac crest. Possible mechanism of increased bone density and protection against osteoporosis. Arthritis Rheum 1993; 36: 1702–8
  • Eingartner C, Coerper S, Fritz J, Gaissmaier C, Koveker G, Weise K. Growth factors in distraction osteogenesis. Immuno-histological pattern of TGF-beta1 and IGF-I in human callus induced by distraction osteogenesis. Int Orthop 1999; 23: 253–9
  • Elmengaard B, Bechtold JE, Soballe K. In vivo effects of RGD-coated titanium implants inserted in two bone-gap models. J Biomed Mater Res A 2005; 75(2)249–55
  • Gundersen HJ, Bendtsen TF, Korbo L, Marcussen N, Moller A, Nielsen K, Nyengaard JR, Pakkenberg B, Sorensen FB, Vesterby A. Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. APMIS 1988; 96: 379–94
  • Hauptfleisch J, Glyn-Jones S, Beard DJ, Gill HS, Murray DW. The premature failure of the Charnley Elite-Plus stem: a confirmation of RSA predictions. J Bone Joint Surg (Br) 2006; 88: 179–83
  • Kandziora F, Schmidmaier G, Schollmeier G, Bail H, Pflugmacher R, Gorke T, Wagner M, Raschke M, Mittlmeier T, Haas NP. IGF-I and TGF-beta1 application by a poly-(D,L-lactide)-coated cage promotes intervertebral bone matrix formation in the sheep cervical spine. Spine 2002; 27: 1710–23
  • Kandziora F, Pflugmacher R, Scholz M, Schafer J, Schollmeier G, Schmidmaier G, Duda G, Raschke M, Haas NP. Dose-dependent effects of combined IGF-I and TGF-beta1 application in a sheep cervical spine fusion model. Eur Spine J 2003; 12: 464–73
  • Karrholm J, Borssen B, Lowenhielm G, Snorrason F. Does early micromotion of femoral stem prostheses matter? 4-7-year stereoradiographic follow-up of 84 cemented prostheses. J Bone Joint Surg (Br) 1994; 76: 912–7
  • Kelly SJ, Incavo SJ, Beynnon B. The use of a hydroxyapatite-coated primary stem in revision total hip arthroplasty. J Arthroplasty 2006; 21: 64–71
  • Kveiborg M, Flyvbjerg A, Eriksen EF, Kassem M. Transforming growth factor-beta1 stimulates the production of insulin-like growth factor-I and insulin-like growth factor-binding protein-3 in human bone marrow stromal osteoblast progenitors. J Endocrinol 2001; 169: 549–61
  • Lamberg A, Schmidmaier G, Soballe K, Elmengaard B. Locally delivered TGF-beta 1 and IGF-1 enhance the fixation of titanium implants - A study in dogs. Acta Orthopaedica 2006; 77: 799–805
  • Lammens J, Liu Z, Aerssens J, Dequeker J, Fabry G. Distraction bone healing versus osteotomy healing: a comparative biochemical analysis. J Bone Miner Res 1998; 13: 279–86
  • Lind M, Overgaard S, Nguyen T, Ongpipattanakul B, Bunger C, Soballe K. Transforming growth factor-beta stimulates bone ongrowth. Hydroxyapatite-coated implants studied in dogs. Acta Orthop Scand 1996a; 67: 611–6
  • Lind M, Overgaard S, Ongpipattanakul B, Nguyen T, Bunger C, Soballe K. Transforming growth factor-beta 1 stimulates bone ongrowth to weight-loaded tricalcium phosphate coated implants: an experimental study in dogs. J Bone Joint Surg (Br) 1996b; 78: 77–82
  • Nicolas V, Prewett A, Bettica P, Mohan S, Finkelman RD, Baylink DJ, Farley JR. Age-related decreases in insulin-like growth factor-I and transforming growth factor-beta in femoral cortical bone from both men and women: implications for bone loss with aging. J Clin Endocrinol Metab 1994; 78: 1011–6
  • Overgaard S, Soballe K, Jorgen H, Gundersen G. Efficiency of systematic sampling in histomorphometric bone research illustrated by hydroxyapatite-coated implants: optimizing the stereological vertical-section design. J Orthop Res 2000; 18: 313–21
  • Pfeilschifter J, Erdmann J, Storch S, Ziegler R, Weinreb M. Changes in the concentration of insulin-like growth factor I and transforming growth factor beta1 in rat femoral bone during growth. Calcif Tissue Int 1999; 64: 78–82
  • Rose FR, Hou Q, Oreffo RO. Delivery systems for bone growth factors - the new players in skeletal regeneration. J Pharm Pharmacol 2004, 56: 415–27
  • Schmidmaier G, Wildemann B, Bail H, Lucke M, Fuchs T, Stemberger A, Flyvbjerg A, Haas NP, Raschke M. Local application of growth factors (insulin-like growth factor-1 and transforming growth factor-beta1) from a biodegradable poly(D,L-lactide) coating of osteosynthetic implants accelerates fracture healing in rats. Bone 2001a; 28: 341–50
  • Schmidmaier G, Wildemann B, Stemberger A, Haas NP, Raschke M. Biodegradable poly(D,L-lactide) coating of implants for continuous release of growth factors. J Biomed Mater Res 2001b; 58: 449–55
  • Schmidmaier G, Wildemann B, Gabelein T, Heeger J, Kandziora F, Haas NP, Raschke M. Synergistic effect of IGF-I and TGF-beta1 on fracture healing in rats: single versus combined application of IGF-I and TGF-beta1. Acta Orthop Scand 2003; 74: 604–10
  • Soballe K, Hansen ES, Brockstedt-Rasmussen H, Pedersen CM, Bunger C. Hydroxyapatite coating enhances fixation of porous coated implants. A comparison in dogs between press fit and noninterference fit. Acta Orthop Scand 1990; 61: 299–306
  • Soballe K, Hansen ES, Rasmussen H, Jorgensen PH, Bunger C. Tissue ingrowth into titanium and hydroxyapatite-coated implants during stable and unstable mechanical conditions. J Orthop Res 1992; 10: 285–99
  • Soballe K, Toksvig-Larsen S, Gelineck J, Fruensgaard S, Hansen ES, Ryd L, Lucht U, Bunger C. Migration of hydroxyapatite coated femoral prostheses. A Roentgen Stereophotogrammetric study. J Bone Joint Surg (Br) 1993; 75: 681–7
  • Soballe K, Mouzin OR, Kidder LA, Overgaard S, Bechtold JE. The effects of hydroxyapatite coating and bone allograft on fixation of loaded experimental primary and revision implants. Acta Orthop Scand 2003; 74: 239–47
  • Soballe K, Jensen TB, Mouzin O, Kidder L, Bechtold JE. Differential effect of a bone morphogenetic protein-7 (OP-1) on primary and revision loaded, stable implants with allograft. J Biomed Mater Res 2004; 71A: 569–76
  • Sumner DR, Turner TM, Urban RM, Virdi AS, Inoue N. Additive enhancement of implant fixation following combined treatment with rhTGF-beta2 and rhBMP-2 in a canine model. J Bone Joint Surg (Am) 2006; 88: 806–17

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