Advanced search
Publication Cover
Acta Orthopaedica Volume 87, 2016 - Issue 4
Journal homepage
1,795
Views
13
CrossRef citations to date
0
Altmetric
Original Articles

2-stage revision of 120 deep infected hip and knee prostheses using gentamicin-PMMA beads

Results after 5 (2–20) years

Daniël M C JanssenDepartment of Orthopedic Surgery, Research School CAPHRI, Maastricht University Medical Centre, Maastricht, the Netherlands
,
Jan A P GeurtsDepartment of Orthopedic Surgery, Research School CAPHRI, Maastricht University Medical Centre, Maastricht, the Netherlands
,
Liesbeth M C JüttenDepartment of Orthopedic Surgery, Research School CAPHRI, Maastricht University Medical Centre, Maastricht, the Netherlands
&
Geert H I M WalenkampDepartment of Orthopedic Surgery, Research School CAPHRI, Maastricht University Medical Centre, Maastricht, the NetherlandsCorrespondence[email protected]
Pages 324-332 | Received 28 Feb 2015, Accepted 06 Dec 2015, Published online: 28 Jan 2016

  • Bejon P, Berendt A, Atkins B L, Green N, Parry H, Masters S, et al. Two-stage revision for prosthetic joint infection: predictors of outcome and the role of reimplantation microbiology. J Antimicrob Chemother 2010; 65(3): 569–75.
  • Berbari E F, Hanssen A D, Duffy M C, Steckelberg J M, Ilstrup D M, Harmsen W S, et al. Risk factors for prosthetic joint infection: case-control study. Clin Infect Dis 1998; 27(5): 1247–54.
  • Beswick A D, Elvers K T, Smith A J, Gooberman-Hill R, Lovering A, Blom A. What is the evidence base to guide surgical treatment of infected hip prosthesis? Systematic review of longitudinal studies in unselected patients. BMC Medicine 2012; 10: 18.
  • Burnett R S J, Kelly M A, Hanssen A D, Barrack R L. Technique and timing of two-stage exchange for infection inTKA. Clin Orthop Relat Res 2007; 464: 164–78.
  • Chen W-S, Fu T-H, Wang J-W. Two-stage reimplantation of infected hip arthroplasty. Chang Gung Med J 2009; 32(2): 188–97.
  • Chen A, Haddad F S, Lachiewicz P, Bolognesi M, Cortes L E, Franceschini M, et al. Prevention of late PJI. J Arthroplasty 2014; 29((Suppl 1)): 119–28.
  • Cierny G, DiPasquale D. Periprosthetic joint infections: staging, treatment, and outcome. Clin Orthop Relat Res 2002; 403: 23–8.
  • Garvin K L, Evans B G, Salvati E A, Brause B D. Palacos gentamicin for the treatment of deep periprosthetic hip infections. Clin Orthop Relat Res 1994; (298): 97–105.
  • Geurts J A, Janssen D M, Kessels A G, Walenkamp G H. Good results in postoperative and hematogenous deep infections of 89 stable total hip and knee replacements with retention of prosthesis and local antibiotics. Acta Orthop 2013; 84(6): 509–16.
  • Ghanem E, Azzam K, Seeley M, Joshi A, Parvizi J. Staged revision for knee arthroplasty infection: what is the role of serologic tests before reimplantation? Clin Orthop Relat Res 2009; 467(7): 1699–705.
  • Greene N, Holtom P D, Warren C A, Ressler R L, Shepherd L, McPherson E J, et al. In vitro elution of tobramycin and vancomycin polymethylmethacrylate beads and spacers from Simplex and Palacos. Am J Orthop (Belle Mead NJ) 1998; 27(3): 201–5.
  • Haddad F S, Masri B A, Campbell D, McGraw R W, Beauchamp C P, Duncan C P. The PROSTALAC functional spacer in two-stage revision for infected knee replacements. Prosthesis of antibiotic-loaded acrylic cement. J Bone Joint Surg Br 2000; 82(6): 807–12.
  • Hansen A D, Spangehl M J. Treatment of the infected hip replacement. Clin Orthop Relat Res 2004; 420: 63–71.
  • Hoad-Reddick D A, Evans C R, Norman P, Stockley I. Is there a role for extended antibiotic therapy in a two-stage revision of the infected knee arthroplasty? J Bone Joint Surg Br 2005; 87(2): 171–4.
  • Hovelius L, Josefsson G. An alternative method for exchange operation of infected arthroplasty. Acta Orthop Scand 1979; 50: 93–6.
  • Hsieh P H, Shih C H, Chang Y H, Lee M S, Shih H N, Yang W E. Two-stage revision hip arthroplasty for infection: comparison between the interim use of antibiotic-loaded cement beads and a spacer prosthesis. J Bone Joint Surg Am 2004; 86-A(9): 1989–97.
  • Joseph J, Raman R, Macdonald D A. Time interval between first and second stage revision hip arthroplasty for infection, the effect on outcome. J Bone Joint Surg Br 2003; 85-B(Suppl): 58.
  • Joulie D, Girard J, Mares O, Beltrand E, Legout L, Dezeque H, et al. Factors governing the healing of Staphylococcus aureus infections following hip and knee prosthesis implantation: a retrospective study of 95 patients. Orthop Traumatol Surg Res 2011; 97(7): 685–92.
  • Kusuma S K, Ward J, Jacofsky M, Sporer S M, Della Valle C J. What is the role of serological testing between stages of two-stage reconstruction of the infected prosthetic knee? Clin Orthop Relat Res 2011; 469(4): 1002–8.
  • Lange J, Troelsen A, Thomsen R W, Søballe K. Chronic infections in hip arthroplasties: comparing risk of reinfection following one-stage and two-stage revision: a systematic review and meta-analysis. Clin Epidemiol 2012; 4: 57–73.
  • Langlais F. Can we improve the results of revision arthroplasty for infected total hip replacement? J Bone Joint Surg Br 2003; 85(5): 637–40.
  • Lenoble E, Goutallier D. [Replacement of infected total hip prosthesis in two stages]. Int Orthop 1995; 19(3): 151–6.
  • Leonard H A, Liddle A D, Burke O, Murray D W, Pandit H. Single- or two-stage revision for infected total hip arthroplasty? A systematic review of the literature. Clin Orthop Relat Res 2014; 472(3): 1036–42.
  • McPherson E J, Woodson C, Holtom P, Roidis N, Shufelt C, Patzakis M. Periprosthetic total hip infection. Clin Orthop Relat Res 2002; 403: 8–15.
  • Mooijen D J, Hentenaar B, Vogely C H, Verbout A J, Castelein R M, Dhert W J. In vitro release of antibiotics from commercial PMMA beads and articulating hip spacers. J Arthroplasty 2008; 23(8): 1152–2256.
  • Osmon D R, Berbari E F, Berendt A R, Lew D, Zimmerli W, Steckelberg J M, et al. Diagnosis and management of prosthetic joint infection: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis 2013; 56(1): e1–e25.
  • Puhto A P, Puhto T M, Niinimaki T T, Leppilahti J I, Syrjala H P. Two-stage revision for prosthetic joint infection: outcome and role of reimplantation microbiology in 107 cases. J Arthroplasty 2014; 29(6): 1101–4.
  • Sabry F Y, Buller L, Ahmed S, Klika A K, Barsoum W K. Preoperative prediction of failure following two-stage revision for knee prosthetic joint infections. J Arthroplasty 2014; 29(1): 115–21.
  • Salvati E A, Callaghan J J, Brause B D, Klein R F, Small R D. Reimplantation in infection. Elution of gentamicin from cement and beads. Clin Orthop Relat Res 1986; (207): 83–93.
  • Scott I R, Stockley I, Getty C J M. Exchange arthroplasty for infected knee replacements. J Bone Joint Surg Br 1993; 75-B(1): 28–31.
  • Sorli L, Puig L, Torres-Claramunt R, González A, Alier A, Knobel H, et al. The relationship between microbiology results in the second of a two-stage exchange procedure using cement spacers and the outcome after revision total joint replacement for infection. J Bone Joint Surg Br 2012; 94-B(2): 249–53.
  • Stockley I, Mockford B J, Hoad-Reddick A, Norman P. The use of two-stage exchange arthroplasty with depot antibiotics in the absence of long-term antibiotic therapy in infected total hip replacement. J Bone Joint Surg Br 2008; 90(2): 145–8.
  • Taggart T, Kerry R M, Norman P, Stockley I. The use of vancomycin-impregnated cement beads in the management of infection of prosthetic joints. J Bone Joint Surg Br 2002; 84-B(1): 70–2.
  • Trampuz A, Zimmerli W. Prosthetic joint infections: update in diagnosis and treatment. Swiss Med Wkly 2005; 135(17-18): 243–51.
  • Walenkamp G H I M. Gentamicin-PMMA beads. A clinical, pharmacokinetic and toxicological study. PhD thesis Nijmegen, ISBN 90-9000470-X, 1983.
  • Walenkamp G H, Vree T B, van Rens T J. Gentamicin-PMMA beads. Pharmacokinetic and nephrotoxicological study. Clin Orthop Relat Res 1986: (205): 171–83.
  • Willenegger H, Ledermann M, Wahl H G, Plaass U. Über das Wesen der Spüldrainage. In: Die Posttraumatische Osteomyelitis. (Ed Hierholzer G, Rehn J). Ch. Stuttgart: Schattauer Verlag; 1970. p. 79–85.
  • Witsø E. The rate of prosthetic joint infection is underestimated in the arthroplasty registers. Acta Orthop 2015; 86(3): 277–8.
  • Zimmerli W, Ochsner P E. Management of infection associated with prosthetic joints. Infection 2003; 31(2): 99–108.
  • Zimmerli W, Trampuz A, Ochsner P E. Prosthetic-joint infections. N Engl J Med 2004; 351(16): 1645–54.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.