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Acta Orthopaedica Scandinavica Volume 47, 1976 - Issue 3
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Original Article

The Penetration of Lincomycin into Normal Human Bone: Determinations of Penetration into Compact Bone, Spongy Bone and Bone Marrow

M. Lykkegaard Nielsen Department of Orthopaedic Surgery, Rigshospitalet, Department of Clinical Microbiology, The Institute of Medical Microbiology, University of Copenhagen, Denmark
,
I. Hansen Department of Orthopaedic Surgery, Rigshospitalet, Department of Clinical Microbiology, The Institute of Medical Microbiology, University of Copenhagen, Denmark
&
J. Boss Nielsen Department of Orthopaedic Surgery, Rigshospitalet, Department of Clinical Microbiology, The Institute of Medical Microbiology, University of Copenhagen, Denmark
Pages 267-270 | Accepted 15 Dec 1975, Published online: 08 Jul 2009

References

  • Evaskus D. S., Laskin D. M., Kroeger A. V. Penetration of lincomycin, penicillin and tetracycline into serum and bone. Proc. Soc. exp. Biol. (N.Y.) 1969; 130: 89–91
  • Garrod L. P., O'Grady F. Antibiotic and chemotherapy, L. P. Garrod, F. O'Grady. Livingstone, London 1972; 266–267
  • Geddes A. M., Munro J. F., McMurdoch J. C., Begg K. J., Burns B. A. Four years hospital experience with lincomycin hydrochloride. 5th Int. Congr. Chemother., Vienna 1967; Vol. I: 361–369
  • Grady J. E., Stern K. F. Penetration of lincomycin into bone. Antimicrob. Agents Chemother. 1965; 201–205, 1966
  • Hansen I., Lykkegaard Nielsen M., Nielsen J. B. A new method for homogenization of bone exemplified by measurement of trimethoprim in human bone tissue. Acta Pharmacol, toxicol. (Kbh.) 1975; 37: 33–42
  • Holloway W. J., Kahlbaugh R. A., Scott E. G. Lincomycin: a clinical study. Anti-microb. Agents Chemother. 1963; 200–203, 1964
  • Linzenmeier G., Schäfer P., Gatos M. Bestimmung der Konzentration von Lincomycin in chronisch entzündetem Knochen-und Weichteilgewebe des Menschen. Arz-neimittel.-Forsch. 1968; 18: 204–207
  • Mason D. J., Dietz A., Deboer G. Lincomycin, a new antibiotic. I. Discovery and biological properties. Antimicrob. Agents Chemother. 1962; 554–559, 1963
  • Nielsen M. L., Hansen I. Trimethoprim in human prostatic tissue and prostatic fluid. Scand. J. Urol. Nephrol. 1972; 6: 244–248
  • Vacek V., Hejzlar M., Pavlansky R. Penetration of lincomycin into bone in man. 5th Int. Congr. Chemother, Vienna, 1967. Vol. I: 345–353

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