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Original Article

Reduced ischemia-reperfusion injury in muscle Experiments in rats with EPC-K1, a new radical scavenger

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Pages 369-373 | Received 27 Nov 1996, Accepted 28 Apr 1997, Published online: 08 Jul 2009

References

  • Bulkley G B. The role of oxygen free radicals in human disease processes. Surgery 1983; 94: 407–11
  • Feller A M, Roth A C, Russell R C, Eagleton B, Suchy H, Debs N. Experimental evaluation of oxygen free radical scavengers in the prevention of reperfusion injury to skeletal muscle. Ann Plast Surg 1989; 22(4)321–31
  • Fish J S, McKee N H, Pynn B R, Kuzon W M, Plyley M J. Isometric contractile function recovery following tourniquet ischemia. J Surg Res 1989; 47: 365–70
  • Korthuis R J, Granger D N, Townsley M I, Taylor A E. The role of oxygen-derived free radicals in ischemia-induced increases in canine skeletal muscle vascular permeability. Circ Res 1985; 57(4)599–609
  • Kuribayashi Y, Yoshida K, Sakaue T, Okumura A. In vitro studies on the influence of L-ascorbic acid 2-[3,4-dihy-dro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1 -benzopyran-6yl-hydrogen phosphate] potassium salt on lipid peroxidation and phospholipase A2 activity. Arz-neim-Forsch 1992; 42(9)1072–4
  • Lindsay T, Romaschin A, Walker P M. Free radical mediated damage in skeletal muscle. Microcirc Endothelium Lymphatics 1989; 5: 157–70
  • McCord J M. Oxygen-derived free radicals in postischemic tissue injury. N Engl J Med 1985; 312(3)159–63
  • McCutchan H J, Schwappach J R, Enquist E G, Walden D L, Terada L S, Reiss O K, Leff J A, Repine J E. Xanthine oxidase-derived H202 contributes to reperfusion injury of ischemic skeletal muscle. Am J Physiol 1990; 285: 1415–9
  • Mori A, Edamatsu R, Kohno M, Ohmori S. A new hydroxyl radical scavenger: EPC-K1. Neuroscience 1989; 15: 371–6
  • Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Bio-chem 1979; 95: 351–8
  • Pang C Y. Ischemia-induced reperfusion injury in muscle flaps: pathogenesis and major source of free radicals. J Reconstr Microsurg 1990; 6: 77–83
  • Seyama A. The role of oxygen-derived free radicals and the effect of free radical scavengers on skeletal muscle is-chemia/reperfusion injury. Jpn J Surg 1993; 23: 1060–7
  • Stompro B E, Stevenson T R, Wineinger M A, Sharman R B, Carlsen R C. A reperfusion interval reduces the contractile deficit in skeletal muscle following tourniquet ischemia. Plast Reconstr Surg 1994; 94(7)1003–11
  • Walker P M, Lindsay T F, Labbe R, Mickle D A, Romaschin A D. Salvage of skeletal muscle with free radical scavengers. J Vase Surg 1987; 5(1)68–75
  • Willson R L. Ill-placed iron, oxygen free radicals and disease: some recent and not so recent radiation studies. The biology and chemistry of active oxygen, J V Bannister, W H Bannister. Elsevier, New York, Amsterdam, Oxford 1984; 238–58

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