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Original Article

Protective effect of the endothelin antagonist Bosentan against ischemic skeletal muscle necrosis

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Pages 293-297 | Received 10 Sep 1998, Accepted 06 Mar 1999, Published online: 08 Jul 2009

References

  • Chang H, Wu G J, Wang S M, Hung C R. The role of endo‐thelin‐1 during ischemia‐reperfusion injury. J Formos Med Assoc 1992; 91(12)1182–8
  • Clozel M, Breu V, Gray G A, Kalina B, Loffler B M, Burri K, Cassal J M, Hirth G, Muller M, Neidhart W, et al. Pharmacological characterization of bosentan, a new potent orally active nonpeptide endothelin receptor antagonist. J Pharmacol Exp Ther 1994; 270(1)228–35
  • Ekelund U. In vivo effects of endothelin‐2, endothelin‐3 and ETA receptor blockade on arterial, venous and capillary functions in cat skeletal muscle. Acta Physiol Scand 1994; 150(1)47–56
  • Ekelund U, Adner M, Edvinsson L, Mellander S. Effects of the combined ETA and ETB receptor antagonist PD145065 on arteries, arterioles, and veins in the cat hindlimb. J Cardiovasc Pharmacol 1995; 26((Suppl 3))211–3
  • Elferink J G, de Koster B M. Modulation of human neutrophil chemotaxis by the endothelin‐B receptor agonist sa‐rafotoxin S6c. Chem Biol Interact 1996; 101(3)165–74
  • Filep J G, Fournier A, Foldes‐Filep E. Acute pro‐inflammatory actions of endothelin‐1 in the guinea‐pig lung: involvement of ETA and ETB receptors. Br J Pharmacol 1995; 115(2)227–36
  • Helset E, Lindal S, Olsen R, Myklebust R, Jorgensen L. Endothelin‐1 causes sequential trapping of platelets and neutrophils in pulmonary microcirculation in rats. Am J Physiol 1996; 271: L538–46
  • Hvaal K, Øie E, Attramadal H, Halvorsen V, Svindland A, Nordsletten L, Skjeldal S. Endothelin‐1 is upregulated during skeletal muscle ischemia and reperfusion. J Or‐thopRes 1998; 16(1)128–35
  • Ishizaki T, Shigemori K, Ameshima S, Nakai T, Miyabo S, Hayakawa M, Ozawa T, Voelkel N F. Protective effects of BQ‐123, an ETA receptor antagonist, against leuko‐toxin‐induced injury in rat lungs. Am J Physiol 1996; 271: L459–63
  • Joshua I G. Endothelin‐induced vasoconstriction of small resistance vessels in the microcirculation of the rat cre‐master muscle. Microvasc Res 1990; 40(2)191–8
  • Khimenko P L, Moore T M, Taylor A E. Blocked ETA receptors prevent ischemia and reperfusion injury in rat lungs. J Appl Physiol 1996; 80(1)203–7
  • Kvernebo K, Staxrud L E, Salerud E G. Assessment of human muscle blood perfusion with single‐fiber laser Dop‐pler flowmetry. Microvasc Res 1990; 39(3)376–85
  • McCarron R M, Wang L, Stanimirovic D B, Spatz M. Endothelin induction of adhesion molecule expression on human brain microvascular endothelial cells. Neurosci Lett 1993; 156: 31–4
  • Skjeldal S, Grøgaard B, Reikerås O, Muller C, Torvik A, Svindland A. Model for skeletal muscle ischemia in rat hindlimb: evaluation of reperfusion and necrosis. Eur Surg Res 1991; 23: 355–65
  • Skjeldal S, Grøgaard B, Nordsletten L, Reikerås O, Svindland A, Torvik A. Protective effect of low‐grade hypothermia in experimental skeletal muscle ischemia. Eur Surg Res 1992; 24(4)197–203
  • Skjeldal S, Torvik A, Grøgaard B, Nordsletten L, Lyberg T. Histological studies on postischemic rat skeletal muscles. With emphasis on the time of leukocyte invasion. Eur Surg Res 1993; 25(6)348–57
  • Skjeldal S, Hvaal K, Nordsletten L, Aasen A O, Reikerås O, Torvik A. Pentoxifylline reduces skeletal muscle necrosis after acute hindlimb ischemia in rats. Eur Surg Res 1994; 26(2)94–100
  • Wang Q D, Li X S, Lundberg J M, Pernow J. Protective effects of non‐peptide endothelin receptor antagonist bosentan on myocardial ischaemic and reperfusion injury in the pig. Cardiovasc Res 1995; 29(6)805–12
  • Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Koba‐yashi M, Mitsui Y, Yazaki Y, Goto K, Masaki T. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988; 332(6163)411–5

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