38
Views
12
CrossRef citations to date
0
Altmetric
Mechanisms

Delayed ghrelin suppression following oral glucose tolerance test in children and adolescents with hypothalamic injury secondary to craniopharyngioma compared with obese controls

, , , &
Pages 285-288 | Received 19 Apr 2010, Published online: 04 Nov 2010

References

  • Coll AP, Farooqi IS, O'Rahilly S. The hormonal control of food intake. Cell. 2007;129(2):251–62.
  • Soriano-Guillen L, Barrios V, Martos G . Effect of oral glucose administration on ghrelin levels in obese children. Eur J Endocrinol. 2004;151(1):119–21.
  • Gil-Campos M, Aguilera CM, Canete R . Ghrelin: a hormone regulating food intake and energy homeostasis. Br J Nutr. 2006;96(2):201–26.
  • Muller HL, Bueb K, Bartels U . Obesity after childhood craniopharyngioma—German multicenter study on pre-operative risk factors and quality of life. Klin Padiatr. 2001; 213(4):244–9.
  • Sklar CA, Mertens AC, Walter A . Changes in body mass index and prevalence of overweight in survivors of childhood acute lymphoblastic leukemia: role of cranial irradiation. Med Pediatr Oncol. 2000;35(2):91–5.
  • Bray GA. Genetic, hypothalamic and endocrine features of clinical and experimental obesity. Prog Brain Res. 1992;93:333–40; discussion: 40–1.
  • Lustig RH, Rose SR, Burghen GA . Hypothalamic obesity caused by cranial insult in children: altered glucose and insulin dynamics and reversal by a somatostatin agonist. J Pediatr. 1999;135(2 Pt 1):162–8.
  • Kuczmarski RJ, Ogden CL, Guo SS . 2000 CDC Growth Charts for the United States: methods and development. Vital Health Stat 11. 2002;(246):1–190.
  • Retnakaran R, Shen S, Hanley AJ . Hyperbolic relationship between insulin secretion and sensitivity on oral glucose tolerance test. Obesity (Silver Spring). 2008;16(8):1901–7.
  • Ariyasu H, Takaya K, Hosoda H . Delayed short-term secretory regulation of ghrelin in obese animals: evidenced by a specific RIA for the active form of ghrelin. Endocrinology. 2002;143(9):3341–50.
  • Bacha F, Arslanian SA. Ghrelin suppression in overweight children: a manifestation of insulin resistance? J Clin Endocrinol Metab. 2005;90(5):2725–30.
  • Goldstone AP, Patterson M, Kalingag N . Fasting and postprandial hyperghrelinemia in Prader-Willi syndrome is partially explained by hypoinsulinemia, and is not due to peptide YY3-36 deficiency or seen in hypothalamic obesity due to craniopharyngioma. J Clin Endocrinol Metab. 2005; 90(5):2681–90.
  • Heath RB, Jones R, Frayn KN . Vagal stimulation exaggerates the inhibitory ghrelin response to oral fat in humans. J Endocrinol. 2004;180(2):273–81.
  • Date Y, Murakami N, Toshinai K . The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats. Gastroenterology. 2002;123(4):1120–8.
  • le Roux CW, Neary NM, Halsey TJ . Ghrelin does not stimulate food intake in patients with surgical procedures involving vagotomy. J Clin Endocrinol Metab. 2005;90(8):4521–4.
  • Marshall WA, Tanner JM. Variations in pattern of pubertal changes in girls. Arch Dis Child. 1969;44(235):291–303.
  • Marshall WA, Tanner JM. Variations in the pattern of pubertal changes in boys. Arch Dis Child. 1970;45(239):13–23.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.