38
Views
2
CrossRef citations to date
0
Altmetric
CLINICAL INVESTIGATIONS

Early treatment with abciximab in patients with ST elevation myocardial infarction results in a high rate of normal or near normal blood flow in the infarct related artery

, , , , &
Pages 10-17 | Received 18 Aug 2009, Accepted 22 Nov 2009, Published online: 04 Mar 2010

References

  • Keeley EC, Boura JA, Grines CL. Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials. Lancet 2003;361:13–20.
  • Stenestrand U, Lindback J, Wallentin L. Long-term outcome of primary percutaneous coronary intervention vs prehospital and in-hospital thrombolysis for patients with ST-elevation myocardial infarction. J Am Med Assoc. 2006;296:1749–56.
  • Widimsky P, Bilkova D, Penicka M, Novak M, Lanikova M, Porizka V, . Long-term outcomes of patients with acute myocardial infarction presenting to hospitals without catheterization laboratory and randomized to immediate thrombolysis or interhospital transport for primary percutaneous coronary intervention. Five years' follow-up of the PRAGUE-2 trial. Eur Heart J. 2007;28:679–84.
  • De Luca G, Suryapranata H, Stone GW, Antoniucci D, Tcheng JE, Neumann FJ, . Abciximab as adjunctive therapy to reperfusion in acute ST-segment elevation myocardial infarction: A meta-analysis of randomized trials. J Am Med Assoc. 2005;293:1759–65.
  • Montalescot G, Barragan P, Wittenberg O, Ecollan P, Elhadad S, Villain P, . Platelet glycoprotein IIb/IIIa inhibition with coronary stenting for acute myocardial infarction. N Engl J Med. 2001;344:1895–903.
  • Antoniucci D, Migliorini A, Parodi G, Valenti R, Rodriguez A, Hempel A, . Abciximab-supported infarct artery stent implantation for acute myocardial infarction and long-term survival: A prospective, multicenter, randomized trial comparing infarct artery stenting plus abciximab with stenting alone. Circulation 2004;109:1704–6.
  • Maioli M, Bellandi F, Leoncini M, Toso A, Dabizzi RP. Randomized early versus late abciximab in acute myocardial infarction treated with primary coronary intervention (RELAx-AMI Trial). J Am Coll Cardiol. 2007;49:1517–24.
  • Gibson CM, Kirtane AJ, Murphy SA, Rohrbeck S, Menon V, Lins J, . Early initiation of eptifibatide in the emergency department before primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: results of the time to integrilin therapy in acute myocardial infarction (TITAN)-TIMI 34 trial. Am Heart J. 2006;152:668–75.
  • Rakowski T, Zalewski J, Legutko J, Bartus S, Rzeszutko L, Dziewierz A, . Early abciximab administration before primary percutaneous coronary intervention improves infarct-related artery patency and left ventricular function in high-risk patients with anterior wall myocardial infarction: A randomized study. Am Heart J. 2007;153:360–5.
  • Ortolani P, Marzocchi A, Marrozzini C, Palmerini T, Saia F, Taglieri N, . Long-term effectiveness of early administration of glycoprotein IIb/IIIa agents to real-world patients undergoing primary percutaneous interventions: Results of a registry study in an ST-elevation myocardial infarction network. Eur Heart J. 2009;30:33–43.
  • Dudek D, Siudak Z, Janzon M, Birkemeyer R, Aldama-Lopez G, Lettieri C, . European registry on patients with ST-elevation myocardial infarction transferred for mechanical reperfusion with a special focus on early administration of abciximab—EUROTRANSFER Registry. Am Heart J. 2008;156:1147–54.
  • Ellis SG, Tendera M, de Belder MA, van Boven AJ, Widimsky P, Janssens L, . Facilitated PCI in patients with ST-elevation myocardial infarction. N Engl J Med. 2008;358:2205–17.
  • Stenestrand U, Wallentin L. Early statin treatment following acute myocardial infarction and 1-year survival. J Am Med Assoc. 2001;285:430–6.
  • Lagerqvist B, James SK, Stenestrand U, Lindback J, Nilsson T, Wallentin L. Long-term outcomes with drug-eluting stents versus bare-metal stents in Sweden. N Engl J Med. 2007;356:1009–19.
  • Masoudi FA, Plomondon ME, Magid DJ, Sales A, Rumsfeld JS. Renal insufficiency and mortality from acute coronary syndromes. Am Heart J. 2004;147:623–9.
  • Rao AK, Pratt C, Berke A, Jaffe A, Ockene I, Schreiber TL, . Thrombolysis in myocardial infarction (TIMI) Trial— phase I: Hemorrhagic manifestations and changes in plasma fibrinogen and the fibrinolytic system in patients treated with recombinant tissue plasminogen activator and streptokinase. J Am Coll Cardiol. 1988;11:1–11.
  • De Luca G, Ernst N, Zijlstra F, van't Hof AW, Hoorntje JC, Dambrink JH . Preprocedural TIMI flow and mor ality in patients with acute myocardial infarction treated by primary angioplasty. J Am Coll Cardiol 2004;43:1363–7.
  • Dudek D, Rakowski T, El Massri N, Sorysz D, Zalewski J, Legutko J . Patency of infarct related artery after pharmacological reperfusion during transfer to primary percutaneous coronary intervention influences left ventricular function and one-year clinical outcome. Int J Cardiol 2008;124:326–31.
  • De Luca G, Ernst N, van ‘t Hof AW, Ottervanger JP, Hoorntje JC, Dambrink JH, . Preprocedural thrombolysis in myocardial infarction (TIMI) flow significantly affects the extent of ST-segment resolution and myocardial blush in patients with acute anterior myocardial infarction treated by primary angioplasty. Am Heart J. 2005;150:827–31.
  • Parodi G, Ndrepepa G, Kastrati A, Conti A, Mehilli J, Sciagra R, . Ability of mechanical reperfusion to salvage myocardium in patients with acute myocardial infarction presenting beyond 12 hours after onset of symptoms. Am Heart J. 2006;152:1133–9.
  • Schömig A, Mehilli J, Antoniucci D, Ndrepepa G, Markwardt C, Di Pede F . Mechanical reperfusion in patients with acute myocardial infarction presenting more than 12 hours from symptom onset: a randomized controlled trial. J Am Med Assoc. 2005;293:2865.72.
  • Kastrati A, Mehilli J, Schlotterbeck K, Dotzer F, Dirschinger J, Schmitt C, . Early administration of reteplase plus abciximab vs abciximab alone in patients with acute myocar-dial infarction referred for percutaneous coronary intervention: A randomized controlled trial. J Am Med Assoc. 2004;291:947–54.
  • Keeley EC, Boura JA, Grines CL. Comparison of primary and facilitated percutaneous coronary interventions for ST-elevation myocardial infarction: Quantitative review of randomised trials. Lancet 2006;367:579–88.
  • Montalescot G, Borentain M, Payot L, Collet JP, Thomas D. Early vs late administration of glycoprotein IIb/IIIa inhibitors in primary percutaneous coronary intervention of acute ST-segment elevation myocardial infarction: A meta-analysis. J Am Med Assoc. 2004;292:362–6.
  • Goldsmith HL, McIntosh FA, Shahin J, Frojmovic MM. Time and force dependence of the rupture of glycoprotein IIb-IIIa-fibrinogen bonds between latex spheres. Biophys J. 2000;78:1195–206.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.