Analysis of FGGY as a risk factor for sporadic amyotrophic lateral sclerosis

References

• Rosen DR. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature. 1993; 364: 362
   PubMed Web of Science ®Google Scholar
• Valdmanis PN, Rouleau GA. Genetics of familial amyotrophic lateral sclerosis. Neurology. 2008; 70: 144–52
   PubMed Web of Science ®Google Scholar
• Yang Y, Hentati A, Deng HX, Dabbagh O, Sasaki T, Hirano M, et al. The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis. Nat Genet. 2001; 29: 160–5
   PubMed Web of Science ®Google Scholar
• Nishimura AL, Mitne-Neto M, Silva HC, Richieri-Costa A, Middleton S, Cascio D, et al. A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis. Am J Hum Genet. 2004; 75: 822–31
   PubMed Web of Science ®Google Scholar
• Greenway MJ, Andersen PM, Russ C, Ennis S, Cashman S, Donaghy C, et al. ANG mutations segregate with familial and sporadic amyotrophic lateral sclerosis. Nat Genet. 2006; 38: 411–3
   PubMed Web of Science ®Google Scholar
• Sreedharan J, Blair IP, Tripathi VB, Hu X, Vance C, Rogelj B, et al. TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis. Science. 2008; 319: 1668–72
   PubMed Web of Science ®Google Scholar
• Graham AJ, Macdonald AM, Hawkes CH. British motor neuron disease twin study. J Neurol Neurosurg Psychiatry. 1997; 62: 562–9
   PubMed Web of Science ®Google Scholar
• Figlewicz DA, Krizus A, Martinoli MG, Meininger V, Dib M, Rouleau GA, et al. Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis. Hum Mol Genet. 1994; 3: 1757–61
   PubMed Web of Science ®Google Scholar
• Lambrechts, D, Poesen, K, Fernandez-Santiago, R, Al-Chalabi, A, Del, BR, van Vught, PW, , et al. Meta-analysis of VEGF variations in ALS: increased susceptibility in male carriers of the 2578AA genotype. J Med Genet. 2008 ( Epub ahead of print).
   PubMed Web of Science ®Google Scholar
• Lambrechts D, Storkebaum E, Morimoto M, Del-Favero J, Desmet F, Marklund SL, et al. VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motor neurons against ischaemic death. Nat Genet. 2003; 34: 383–94
   PubMed Web of Science ®Google Scholar
• Goodall, EF, Greenway, MJ, van, Marion I, Carroll, CB, Hardiman, O, Morrison, KE. Association of the H63D polymorphism in the haemochromatosis gene with sporadic ALS. Neurology. 2005;65:934–7.
   PubMed Web of Science ®Google Scholar
• Sutedja NA, Sinke RJ, van Vught PW, van der Linden MW, Wokke JH, van Duijn CM, et al. The association between H63D mutations in HFE and amyotrophic lateral sclerosis in a Dutch population. Arch Neurol. 2007; 64: 63–7
   PubMedGoogle Scholar
• Saeed M, Siddique N, Hung WY, Usacheva E, Liu E, Sufit RL, et al. Paraoxonase cluster polymorphisms are associated with sporadic ALS. Neurology. 2006; 67: 771–6
   PubMed Web of Science ®Google Scholar
• Wills AM, Landers JE, Zhang H, Richter RJ, Caraganis AJ, Cudkowicz ME, et al. Paraoxonase 1 (PON1) organophosphate hydrolysis is not reduced in ALS. Neurology. 2008; 70: 929–34
   PubMed Web of Science ®Google Scholar
• Veldink JH, van den Berg LH, Cobben JM, Stulp RP, de Jong JM, Vogels OJ, et al. Homozygous deletion of the survival motor neuron 2 gene is a prognostic factor in sporadic ALS. Neurology. 2001; 56: 749–52
   PubMed Web of Science ®Google Scholar
• The International HapMap Consortium . A haplotype map of the human genome. Nature. 2005;437:1299–320.
   PubMed Web of Science ®Google Scholar
• Klein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS, Haynes C, et al. Complement factor H polymorphism in age-related macular degeneration. Science. 2005; 308: 385–9
   PubMed Web of Science ®Google Scholar
• Wellcome Trust Case Control Consortium . Genome-wide association study of 14,000 cases of seven common diseases and 3000 shared controls. Nature. 2007;447:661–78.
   PubMed Web of Science ®Google Scholar
• Dunckley T, Huentelman MJ, Craig DW, Pearson JV, Szelinger S, Joshipura K, et al. Whole-genome analysis of sporadic amyotrophic lateral sclerosis. N Engl J Med. 2007; 357: 775–88
   PubMed Web of Science ®Google Scholar
• van Es MA, van Vught PW, Blauw HM, Franke L, Saris CG, Andersen PM, et al. ITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: a genome-wide association study. Lancet Neurol. 2007; 6: 869–77
   PubMed Web of Science ®Google Scholar
• van Es MA, van Vught PW, Blauw HM, Franke L, Saris CG, van den BL, et al. Genetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosis. Nat Genet. 2008; 40: 29–31
   PubMed Web of Science ®Google Scholar
• Schymick JC, Scholz SW, Fung HC, Britton A, Arepalli S, Gibbs JR, et al. Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first-stage analysis and public release of data. Lancet Neurol. 2007; 6: 322–8
   PubMed Web of Science ®Google Scholar
• Cronin S, Berger S, Ding J, Schymick JC, Washecka N, Hernandez DG, et al. A genome-wide association study of sporadic ALS in a homogenous Irish population. Hum Mol Genet. 2008; 17: 768–74
   PubMed Web of Science ®Google Scholar
• Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, Bender D, et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet. 2007; 81: 559–75
   PubMed Web of Science ®Google Scholar
• Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet. 2006; 38: 904–9
   PubMed Web of Science ®Google Scholar
• Falush D, Stephens M, Pritchard JK. Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. Genetics. 2003; 164: 1567–87
   PubMed Web of Science ®Google Scholar
• Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics. 2005; 21: 263–5
   PubMed Web of Science ®Google Scholar
• Bo RD, Ghezzi S, Corti S, Santoro D, Prelle A, Mancuso M, et al. DPP6 gene variability confers increased risk of developing sporadic amyotrophic lateral sclerosis in Italian patients. J Neurol Neurosurg Psychiatry. 2008; 79: 1085
   PubMed Web of Science ®Google Scholar
• Sutedja NA, Veldink JH, Fischer K, Kromhout H, Wokke JH, Huisman MH, et al. Lifetime occupation, education, smoking, and risk of ALS. Neurology 2007; 69: 1508–14
   PubMed Web of Science ®Google Scholar
• Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, Bender D, et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 2007; 81: 559–75
   PubMed Web of Science ®Google Scholar
• Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 2006; 38: 904–9
   PubMed Web of Science ®Google Scholar
• Falush D, Stephens M, Pritchard JK. Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. Genetics 2003; 164: 1567–87
   PubMed Web of Science ®Google Scholar
• The International HapMap Consortium . A haplotype map of the human genome. Nature. 2005;437:1299–320.
   PubMed Web of Science ®Google Scholar