Novel Drug Delivery System of Plant Extract for the Management of Diabetes: An Antidiabetic Study

REFERENCES

• Adikwu Michael U, UzuegbuDavid B, Okoye Theophine C, Uzor Philip F, Maxwell Ogochukwu A, Amadi Benson V. Antidiabetic effect of combined aqueous leaf extract of Vernonia amygdalina and metformin in rats. J Basic Clin Pharm. 2010;1(3):197–202.
   PubMedGoogle Scholar
• Ajali U, Okoye FBC. Antimicrobial and anti-inflammatory activities of Olax viridis root bark extracts and fractions. Int J Applied Res Nat Prod. 2009;2(1):27–32.
   Google Scholar
• Akhtar AH, Ahmad KU. Anti-ulcerogenic evaluation of the methanolic extracts of some indigenous medicinal plants of Pakistan in aspirin-ulcerated rats. J Ethnopharmcol. 1995;46:1–6.
   PubMed Web of Science ®Google Scholar
• Alam G, Singh MP, Singh A. Wound healing potential of some medicinal plants. Int J Pharm Sci Rev Res. 2011;9(1)026:136–149.
   Google Scholar
• Anwar F, Bhanger MI. Analytical characterization of Moringa oleifera seed oil grown in temperate regions of Pakistan. J Agric Food Chem. 2003;51:6558–6563.
   PubMed Web of Science ®Google Scholar
• Asres K. The major constituents of the acetone fraction of Ethiopian Moringa stenopetala leaves. Mansoura J Pharmacol Sci. 1995;11(1):55–64.
   Google Scholar
• Bonati A. How and why should we standardize phytopharmaceutical drugs for clinical validation? J Ethnopharmacol. 1991;32:195–198.
   PubMed Web of Science ®Google Scholar
• British Pharmacopoaeia. The Commision Office London. 2009;111:6578–6585.
   Google Scholar
• Dahanuka SA, Kulkarni RA, Rege NN. Pharmacology of medicinal plants and natural products. Indian J Pharmacol. 2002;2:508–512.
   Google Scholar
• Dolly J, Prashant KB, Amit K, Mehta S, Geeta W. Effect of Moringa oleifera Lam. leaves aqueous extract therapy on hyperglycemic rats. J Ethnopharmacol. 2009;23:392–396.
   Google Scholar
• Ebong PE, Atangwho IJ, Epyong EU, Ukwe C, Obi A. Pancreatic beta cell regeneration: a probable parallel mechanism of hypoglycaemic action of Vernonia amygdalina Del and Azadirachta indica. Proceedings of the International Neem Conference Kunming, China, 2006, pp. 83–89.
   Google Scholar
• Elisabetsky E, Amadar TA, Albuquerque RR, Nunes DS, Calvalho ACT. Analgesic activity of Psychotria colorata (Willd. Ex R. & S.) Muell Arg Alkaloids. J Ethnopharmacol. 1995;48:77–83.
   PubMed Web of Science ®Google Scholar
• Emeje M, Boyi S, Obidike I, Isimi C, Kunle O, Ofoefule S. Natural antidiabetic compound for the therapeutic management of diabetes mellitus and its drug delivery system. J Diet Suppl. 2011;8(3):266–279.
   PubMedGoogle Scholar
• Etuk EU. Animal models for studying diabetes mellitus. Agric Biol J N Am. 2010;1(2):130–134.
   Google Scholar
• Fahey JW. Moringa oleifera: a review of the medical evidence for its nutritional, therapeutic, and prophylactic properties. Part 1. Trees for Life J. 2005;1:1–5.
   Google Scholar
• Fozia F, Meenu R, Avinash T, Abdul AK, Shaila F. Medicinal properties of Moringa oleifera: An overview of promising healer. J Med Plants Res. 2012;6(27):4368–4374.
   Google Scholar
• Giridhari VVA, Malathi D, Geetha K. Antidiabetic property of drumstick (Moringa oleifera) leaf tablets. Int J Health Nutr. 2011;2(1):1–5.
   Google Scholar
• Harris MI. Diabetes in America (2nd ed.). National Institute of Health, National Institute of Diabetes, and Digestive and Kidney Diseases. NIH (95-1468) 2nd edn. 1995;631–659.
   Google Scholar
• Iwu MW, Duncan AR, Okunji CO. New antimalarials of plant origin. In: J Janick (Ed.), Perspective on new crops and new uses, pp. 457–462. Alexandria, VA: ASHS Press, 1999.
   Google Scholar
• James E, Singh G, Larry L, Vinod P. Method to compare dissolution profiles and a rationale for wide dissolution specification for metoprolol tartarate tablets. J Pharm Sci. 1997;86:690–700.
   PubMed Web of Science ®Google Scholar
• Mensah JK, Ikhajiagbe B, Edema NE, Emokhor J. Phytochemical, nutritional and antibacterial properties of dried leaf powder of Moringa oleifera (Lam) from Edo Central Province, Nigeria. J Nat Pro Plant Res. 2012;2(1):107–112.
   Google Scholar
• Muhammad A, Syed BSN, Shahnaz G. Development of coprocessed micro granules for direct compression. Int J Pharm Pharm Sci. 2011;1,3(2):64–69.
   Google Scholar
• Nachaegari SK, Bansal AK. Coprocessed excipients for solid dosage forms. Pharm Technol. 2004;52–64.
   Google Scholar
• Nnamani PO, Attama AA, Ibezim EC, Adikwu MU. SRMS 142-based solid lipid microparticles: Application in oral delivery of glibenclamide to diabetic rats. Eur J Pharm Biopharm. 2010;76:68–74.
   PubMed Web of Science ®Google Scholar
• Ofokansi KC, Adikwu MU, Okore VC. Preparation and evaluation of mucin-gelatin mucoadhesive microspheres for rectal delivery of ceftriaxone sodium. Drug Dev Ind Pharm. 2007;33:691–700.
   PubMed Web of Science ®Google Scholar
• Patwardhan B. Ethnopharmacology and drug discovery. J Ethnopharmacol. 2005;100:50–52.
   PubMed Web of Science ®Google Scholar
• Robbers J, Speedie M, Tyler V. Pharmacognosy and harmacobiotechnology. Baltimore: Williams and Wilkins. 1996;1–4.
   Google Scholar
• Shangraw RF. Compressed tablets by direct compression granulation pharmaceutical dosage forms (Tablets Vol. 1, 2nd ed.), pp. 195–246. USA: Marcel Dekker, 1989.
   Google Scholar
• Subadra S, Monica J. Retention and storage stability of beta-carotene in dehydrated drumstick leaves (Moringa oleifera). Int J Food Sci Nut. 1997;48(6):373–379.
   Web of Science ®Google Scholar
• Talhaliani P, Kar A. Role of Moringa oleifera leaf extract in the regulation of thyroid hormone status in adult male and female rats. Pharm Res. 2000;41(3):319–323.
   Google Scholar
• Uchenna V, Okolie I, Chinwe E, Okeke JM, Ijeoma OE. Hypoglycemic indices of Vernonia amygdalina on postprandial blood glucose concentration of healthy humans. Afric J Biotechnol. 2008;7(24):4581–4585.
   Google Scholar
• Vivek KS, Suresh K, Hitesh JP, Shivakumar H. Hypoglycemic activity of Ficus glomerata in alloxan induced diabetic rats. Int J Pharm Sci Rev & Res. 2010;1(2):18–22.
   Google Scholar
• World Health Organisation and International Diabetes Federation in Europe. The Saint Vincent Declaration. 1989.
   Google Scholar