Association of rs6166 polymorphism with FSH receptor transcript variants and steroid production in human granulosa cell cultures

References

• Aittomäki, K., Lucena, J.L., Pakarinen, P., Sistonen, P., Tapanainen, J., Gromoll, J. (1995) Mutation in the follicle-stimulating hormone receptor gene causes hereditary hypergonadotropic ovarian failure. Cell 82:959–968.
   PubMed Web of Science ®Google Scholar
• Binder, H., Dittrich, R., Hager, I., Müller, A., Oeser, S., Beckmann, M.W. (2008) Association of FSH receptor and CYP19A1 gene variations with sterility and ovarian hyperstimulation syndrome. Reproduction 135:107–116.
   PubMed Web of Science ®Google Scholar
• Cai, J., Lou, H.Y., Dong, M.Y., Lu, X.E., Zhu, Y.M., Gao, H.J. (2007) Poor ovarian response to gonadotropin stimulation is associated with low expression of follicle-stimulating hormone receptor in granulosa cells. Fertil Steril 87:1350–1356.
   PubMed Web of Science ®Google Scholar
• Desai, S.S., Achrekar, S.K., Pathak, B.R., Desai, S.K., Mangoli, V.S., Mangoli, R.V. (2011) Follicle-stimulating hormone receptor polymorphism (G-29A) is associated with altered level of receptor expression in Granulosa cells. J Clin Endocrinol Metab 96:2805–2812.
   PubMed Web of Science ®Google Scholar
• Dickey, R.P., Thornton, M., Nichols, J., Marshall, D.C., Fein, S.H., Nardi, R.V. (2002) Comparison of the efficacy and safety of a highly purified human follicle-stimulating hormone (Bravelle) and recombinant follitropin-beta for in vitro fertilization: a prospective, randomized study. Fertil Steril 77:1202–1208.
   PubMed Web of Science ®Google Scholar
• Findlay, J.K. and Drummond, A.E. (1999) Regulation of the FSH Receptor in the Ovary. Trends Endocrinol Metab 10:183–188.
   PubMed Web of Science ®Google Scholar
• Gerasimova, T., Thanasoula, M.N., Zattas, D., Seli, E., Sakkas, D. and Lalioti, M.D. (2010) Identification and in vitro characterization of follicle stimulating hormone (FSH) receptor variants associated with abnormal ovarian response to FSH. J Clin Endocrinol Metab 95:529–536.
   PubMedGoogle Scholar
• Johnson, A.D., Wang, D. and Sadee, W. (2005) Polymorphisms affecting gene regulation and mRNA processing: broad implications for pharmacogenetics. Pharmacol Ther 106:19–38.
   PubMed Web of Science ®Google Scholar
• Jun, J.K., Yoon, J.S., Ku, S.Y., Choi, Y.M., Hwang, K.R., Park, S.Y. (2006) Follicle-stimulating hormone receptor gene polymorphism and ovarian responses to controlled ovarian hyperstimulation for IVF-ET. J Hum Genet 51:665–670.
   PubMed Web of Science ®Google Scholar
• Klinkert, E.R., Broekmans, F.J., Looman, C.W., Habbema, J.D. and te Velde, E.R. (2005) Expected poor responders on the basis of an antral follicle count do not benefit from a higher starting dose of gonadotrophins in IVF treatment: a randomized controlled trial. Hum Reprod 20:611–615.
   PubMed Web of Science ®Google Scholar
• Lobb, D.K. and Younglai, E.V. (2006) A simplified method for preparing IVF granulosa cells for culture. J Assist Reprod Genet 23:93–95.
   PubMedGoogle Scholar
• Nembaware, V., Wolfe, K.H., Bettoni, F., Kelso, J. and Seoighe, C. (2004) Allele-specific transcript isoforms in human. FEBS Lett 577:233–238.
   PubMedGoogle Scholar
• Nordhoff, V., Sonntag, B., von Tils, D., Götte, M., Schüring, A.N., Gromoll, J. (2011) Effects of the FSH receptor gene polymorphism p.N680S on cAMP and steroid production in cultured primary human granulosa cells. Reprod Biomed Online 23:196–203.
   PubMed Web of Science ®Google Scholar
• Perez Mayorga, M., Gromoll, J., Behre, H.M., Gassner, C., Nieschlag, E. and Simoni, M. (2000) Ovarian response to follicle-stimulating hormone (FSH) stimulation depends on the FSH receptor genotype. J Clin Endocrinol Metab 85:3365–3369.
   PubMed Web of Science ®Google Scholar
• Pfaffl, M.W., Horgan, G.W. and Dempfle, L. (2002) Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res 30:e36.
   PubMed Web of Science ®Google Scholar
• Sairam, M.R. and Babu, P.S. (2007) The tale of follitropin receptor diversity: a recipe for fine tuning gonadal responses? Mol Cell Endocrinol 260-262:163–171.
   Google Scholar
• Simoni, M., Gromoll, J., Höppner, W., Kamischke, A., Krafft, T., Stähle, D. (1999) Mutational analysis of the follicle-stimulating hormone (FSH) receptor in normal and infertile men: identification and characterization of two discrete FSH receptor isoforms. J Clin Endocrinol Metab 84:751–755.
   PubMed Web of Science ®Google Scholar
• Song, G.J., Park, Y.S., Lee, Y.S., Lee, C.C. and Kang, I.S. (2002) Alternatively spliced variants of the follicle-stimulating hormone receptor gene in the testis of infertile men. Fertil Steril 77:499–504.
   PubMedGoogle Scholar
• Sudo, S., Kudo, M., Wada, S., Sato, O., Hsueh, A.J. and Fujimoto, S. (2002) Genetic and functional analyses of polymorphisms in the human FSH receptor gene. Mol Hum Reprod 8:893–899.
   PubMed Web of Science ®Google Scholar
• Ulloa-Aguirre, A., Zariñán, T., Pasapera, A.M., Casas-González, P. and Dias, J.A. (2007) Multiple facets of follicle-stimulating hormone receptor function. Endocrine 32:251–263.
   PubMedGoogle Scholar
• Vandenbroucke, I.I., Vandesompele, J., Paepe, A.D. and Messiaen, L. (2001) Quantification of splice variants using real-time PCR. Nucleic Acids Res 29:E68–68.
   PubMedGoogle Scholar
• Wunsch, A., Ahda, Y., Banaz-Yaşar, F., Sonntag, B., Nieschlag, E., Simoni, M. (2005) Single-nucleotide polymorphisms in the promoter region influence the expression of the human follicle-stimulating hormone receptor. Fertil Steril 84:446–453.
   PubMedGoogle Scholar