Meta-analysis of gene expression profiling in amyotrophic lateral sclerosis: A comparison between transgenic mouse models and human patients

References

• Malaspina A, Kaushik N, de Belleroche J. Differential expression of 14 genes in amyotrophic lateral sclerosis spinal cord detected using gridded cDNA arrays. J Neurochem. 2001;77:132–45.
   PubMed Web of Science ®Google Scholar
• Dangond F, Hwang D, Camelo S, Pasinelli P, Frosch M, Stephanopoulos G, . Molecular signature of late-stage human ALS revealed by expression profiling of post mortem spinal cord grey matter. Physiol Genomics. 2004;16: 229–39.
   PubMed Web of Science ®Google Scholar
• Jiang Y, Yamamoto M, Kobayashi Y, Yoshihara T, Liang Y, Terao S, . Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis. Ann Neurol. 2005;57:236–51.
   PubMed Web of Science ®Google Scholar
• Wang X, Simmons Z, Liu W, Boyer P, Connor J. Differential expression of genes in amyotrophic lateral sclerosis revealed by profiling the post mortem cortex. Amyotroph Lateral Scler. 2006;7:201–16.
   PubMed Web of Science ®Google Scholar
• Lederer C, Torrisi A, Pantelidou M, Santama N, Cavallaro S. Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis. BMC Genomics. 2007;8:26.
   PubMed Web of Science ®Google Scholar
• Offen D, Barhum Y, Melamed E, Embacher N, Schindler C, Ransmayr G. Spinal Cord mRNA Profile in Patients with ALS: Comparison with Transgenic Mice Expressing the Human SOD-1 Mutant. J Mol Neurosci. 2008.
   Web of Science ®Google Scholar
• Kirby J, Ning K, Ferraiuolo L, Heath PR, Ismail A, Kuo S-W, . Phosphatase and tensin homologue/protein kinase B pathway linked to motor neuron survival in human superoxide dismutase 1-related amyotrophic lateral sclerosis. Brain. 2011:1−12.
   Google Scholar
• Yoshihara T, Ishigaki S, Yamamoto M, Liang Y, Niwa J, Takeuchi H, . Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis. J Neurochem. 2002;80:158–67.
   PubMed Web of Science ®Google Scholar
• Olsen MK, Roberds SL, Ellerbrock BR, Fleck TJ, Mckinley DK, Gurney ME. Disease mechanisms revealed by transcription profiling in SOD1-G93A transgenic mouse spinal cord. Ann Neurol. 2002;50:730–40.
   Web of Science ®Google Scholar
• Perrin F, Boisset G, Docquier M, Schaad O, Descombes P, Kato A. No widespread induction of cell death genes occurs in pure motor neurons in an amyotrophic lateral sclerosis mouse model. Hum Mol Genet. 2005;14:3309–20.
   PubMed Web of Science ®Google Scholar
• Perrin F, Boisset G, Lathuiliere A, Kato A. Cell death pathways differ in several mouse models with motor neuron disease: analysis of pure motor neuron populations at a presymptomatic age. J Neurochem. 2006;98:1959–72.
   PubMed Web of Science ®Google Scholar
• Fukada Y, Yasui K, Kitayama M, Doi K, Nakano T, Watanabe Y, . Gene expression analysis of the murine model of amyotrophic lateral sclerosis: studies of the Leu126delTT mutation in SOD1. Brain Res. 2007; 1160:1–10.
   PubMed Web of Science ®Google Scholar
• Ferraiuolo L, Heath PR, Holden H, Kasher P, Kirby J, Shaw PJ. Microarray analysis of the cellular pathways involved in the adaptation to and progression of motor neuron injury in the SOD1-G93A mouse model of familial ALS. J Neurosci. 2007;27:9201–19.
   PubMed Web of Science ®Google Scholar
• D'arrigo A, Colavito D, Peña-Altamira E, Fabris M, Dam M, Contestabile A, . Transcriptional Profiling in the Lumbar Spinal Cord of a Mouse Model of Amyotrophic Lateral Sclerosis: A Role for Wild-Type Superoxide Dismutase 1 in Sporadic Disease?J Mol Neurosci. 2010:1−12.
   Google Scholar
• Kudo LC, Parfenova L, Vi N, Lau K, Pomakian J, Valdmanis P, . Integrative gene-tissue microarray-based approach for identification of human disease biomarkers: application to amyotrophic lateral sclerosis. Human Molecular Genetics. 2010;19:3233–53.
   PubMed Web of Science ®Google Scholar
• Chen H, Guo Y, Hu M, Duan W, Chang G, Li C. Differential expression and alternative splicing of genes in lumbar spinal cord of an amyotrophic lateral sclerosis mouse model. Brain Research. 2010;1340:1−60.
   Google Scholar
• Rosen D, Siddique T, Patterson D, Figlewicz D, Sapp P, Hentati A, . Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature. 1993;362:59–62.
   PubMed Web of Science ®Google Scholar
• Ishigaki S, Niwa J, Ando Y, Yoshihara T, Sawada K, Doyu M, . Differentially expressed genes in sporadic amyotrophic lateral sclerosis spinal cords: screening by molecular indexing and subsequent cDNA microarray analysis. FEBS Lett. 2002;531:354–8.
   PubMed Web of Science ®Google Scholar
• Lincecum JM, Vieira FG, Wang MZ, Thompson K, de Zutter GS, Kidd J, . From transcriptome analysis to therapeutic anti-CD40L treatment in the SOD1 model of amyotrophic lateral sclerosis. Nat Genet. 2010; 42:392–9.
   PubMed Web of Science ®Google Scholar
• Lobsiger CS, Boillée S, Cleveland DW. Toxicity from different SOD1 mutants dysregulates the complement system and the neuronal regenerative response in ALS motor neurons. Proc Natl Acad Sci USA. 2007;104:7319–26.
   PubMed Web of Science ®Google Scholar
• Vargas MR, Pehar M, Díaz-Amarilla PJ, Beckman JS, Barbeito L. Transcriptional profile of primary astrocytes expressing ALS-linked mutant SOD1. J Neurosci Res. 2008; 86:3515–25.
   PubMed Web of Science ®Google Scholar
• Kirby J, Halligan E, Baptista MJ, Allen S, Heath PR, Holden H, . Mutant SOD1 alters the motor neuronal transcriptome: implications for familial ALS. Brain. 2005; 128:1686–706.
   PubMed Web of Science ®Google Scholar
• Lincecum JM, Vieira FG, Wang MZ, Thompson K, de Zutter GS, Kidd J, . From transcriptome analysis to therapeutic anti-CD40L treatment in the SOD1 model of amyotrophic lateral sclerosis. Nat Genet. 2010;42:392–9.
   PubMed Web of Science ®Google Scholar
• Saris CGJ, Horvath S, van Vught PWJ, van Es MA, Blauw HM, Fuller TF, . Weighted gene co-expression network analysis of the peripheral blood from amyotrophic lateral sclerosis patients. BMC Genomics. 2009;10:405.
   PubMed Web of Science ®Google Scholar
• Gonzalez de Aguilar J, Niederhauser-Wiederkehr C, Halter B, de Tapia M, Di Scala F, Demougin P, . Gene profiling of skeletal muscle in an amyotrophic lateral sclerosis mouse model. Physiol Genomics. 2008; 32:207–18.
   PubMed Web of Science ®Google Scholar
• Bendotti C, Marino M, Cheroni C, Fontana E, Crippa V, Poletti A, . Dysfunction of constitutive and inducible ubiquitin-proteasome system in amyotrophic lateral sclerosis: implication for protein aggregation and immune response. Prog Neurobiol.2011;97:101–26.
   Web of Science ®Google Scholar
• Deng H-X, Chen W, Hong S-T, Boycott KM, Gorrie GH, Siddique N, . Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia. Nature. 2011;477:211–5.
   PubMed Web of Science ®Google Scholar
• Nakamura M, Kaneko S, Wate R, Asayama S, Nakamura Y, Fujita K, . Regionally different immunoreactivity for Smurf2 and pSmad2/3 in TDP-43-positive inclusions of amyotrophic lateral sclerosis. Neuropathology and Applied Neurobiology. 2012;
   Web of Science ®Google Scholar
• Morris HR, Waite AJ, Williams NM, Neal JW, Blake DJ. Recent Advances in the Genetics of the ALS-FTLD Complex. Curr Neurol Neurosci Rep. 2012; DOI: 10.1111/j.1365-2990.2012.01270.x.
   Web of Science ®Google Scholar
• Ottervald J, Franzén B, Nilsson K, Andersson LI, Khademi M, Eriksson B, . Multiple sclerosis: identification and clinical evaluation of novel CSF biomarkers. J Proteomics. 2010;73:1117–32.
   PubMed Web of Science ®Google Scholar
• Chou SM, Taniguchi A, Wang HS, Festoff BW. Serpin = * serine protease-like complexes within neurofilament conglomerates of motor neurons in amyotrophic lateral sclerosis. Journal of the Neurological Sciences. 1998;160 (Suppl 1):S73–9.
   Google Scholar
• Glas M, Popp B, Angele B, Koedel U, Chahli C, Schmalix WA, . A role for the urokinase-type plasminogen activator system in amyotrophic lateral sclerosis. Experimental Neurology. 2007;207:350–6.
   PubMed Web of Science ®Google Scholar
• Ince PG, Evans J, Knopp M, Forster G, Hamdalla HHM, Wharton SB, . Corticospinal tract degeneration in the progressive muscular atrophy variant of ALS. Neurology. 2003;60:1252–8.
   PubMed Web of Science ®Google Scholar
• Leigh PN, Abrahams S, Al-Chalabi A, Ampong M-A, Goldstein LH, Johnson J, . The management of motor neuron disease. Journal of Neurology, Neurosurgery & Psychiatry. 2003;74 (Suppl 4):32–47.
   Google Scholar
• van den Berg-Vos RM, Visser J, Franssen H, de Visser M, de Jong JMBV, Kalmijn S, . Sporadic lower motor neuron disease with adult onset: classification of subtypes. Brain. 2003;126:1036–47.
   PubMed Web of Science ®Google Scholar
• Emmert-Buck MR, Bonner RF, Smith PD, Chuaqui RF, Zhuang Z, Goldstein SR, . Laser capture microdissection. Science. 1996;274:998–1001.
   PubMed Web of Science ®Google Scholar
• Bergemalm D, Forsberg K, Jonsson P, Graffmo K, Brännström T, Andersen P, . Changes in the spinal cord proteome of an amyotrophic lateral sclerosis murine model determined by differential in-gel electrophoresis. Mol Cell Proteomics. 2009;8:1306–17.
   PubMed Web of Science ®Google Scholar
• Raoul C, Estévez AG, Nishimune H, Cleveland DW, de Lapeyrière O, Henderson CE, . Motor neuron death triggered by a specific pathway downstream of Fas potentiation by ALS-linked SOD1 mutations. Neuron. 2002;35: 1067–83.
   PubMed Web of Science ®Google Scholar
• Hensley K, Floyd RA, Gordon B, Mou S, Pye QN, Stewart C, . Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G93A-SOD1 mouse model of amyotrophic lateral sclerosis. J Neurochem. 2002;82:365–74.
   PubMed Web of Science ®Google Scholar
• Tang HL, Lung HL, Wu KC, Le A-HP, Tang HM, Fung MC. Vimentin supports mitochondrial morphology and organization. Biochem J. 2008;410:141–6.
   PubMed Web of Science ®Google Scholar
• Perlson E, Hanz S, Ben-Yaakov K, Segal-Ruder Y, Seger R, Fainzilber M. Vimentin-dependent spatial translocation of an activated MAP kinase in injured nerve. Neuron. 2005; 45:715–26.
   PubMed Web of Science ®Google Scholar
• Grewal RP, Morgan TE, Finch CE. C1qB and clusterin mRNA increase in association with neurodegeneration in sporadic amyotrophic lateral sclerosis. Neurosci Lett. 1999; 271:65–7.
   PubMed Web of Science ®Google Scholar
• Olsen MK, Roberds SL, Ellerbrock BR, Fleck TJ, McKinley DK, Gurney ME. Disease mechanisms revealed by transcription profiling in SOD1-G93A transgenic mouse spinal cord. Ann Neurol. 2001;50:730–40.
   PubMed Web of Science ®Google Scholar
• Goldknopf IL, Sheta EA, Bryson J, Folsom B, Wilson C, Duty J, . Complement C3c and related protein biomarkers in amyotrophic lateral sclerosis and Parkinson’s disease. Biochem Biophys Res Commun. 2006;342:1034–9.
   PubMed Web of Science ®Google Scholar
• Bonifati DM, Kishore U. Role of complement in neurodegeneration and neuroinflammation. Mol Immunol. 2007;44: 999–1010.
   PubMed Web of Science ®Google Scholar
• Fonseca MI, Kawas CH, Troncoso JC, Tenner AJ. Neuronal localization of C1q in preclinical Alzheimer’s disease. Neurobiol Dis. 2004;15:40–6.
   PubMed Web of Science ®Google Scholar
• Gasque P, Dean YD, McGreal EP, van Beek J, Morgan BP. Complement components of the innate immune system in health and disease in the CNS. Immunopharmacology. 2000;49:171–86.
   PubMed Web of Science ®Google Scholar