Advanced bile acid-based multi-compartmental microencapsulated pancreatic β-cells integrating a polyelectrolyte-bile acid formulation, for diabetes treatment

References

• Al-Salami H, Butt G, Tucker I, Fawcett PJ, Golocorbin-Kon S, Mikov I, Mikov M. 2009. Gliclazide reduces MKC intestinal transport in healthy but not diabetic rats. Eur J Drug Metab Pharmacokinet. 34:43–50.
   PubMed Web of Science ®Google Scholar
• Al-Salami H, Butt G, Tucker I, Golocorbin-Kon S, Mikov M. 2012. Probiotics decreased the bioavailability of the bile acid analog, monoketocholic acid, when coadministered with gliclazide, in healthy but not diabetic rats. Eur J Drug Metab Pharmacokinet. 37:99–108.
   PubMed Web of Science ®Google Scholar
• Al-Salami H, Butt G, Tucker I, Mikov M. 2008. Influence of the semisynthetic bile acid MKC on the ileal permeation of gliclazide in vitro in healthy and diabetic rats treated with probiotics. Methods Find Exp Clin Pharmacol. 30:107–113.
   PubMed Web of Science ®Google Scholar
• Al-Salami H, Kansara H, King J, Morar B, Jayathilaka B, Fawcett PJ, Mikov M. 2007. Bile acids: a bitter sweet remedy for diabetes. NZ Pharm J. 27:17–20.
   Google Scholar
• Awasthi R, Kulkarni GT. 2013. Development of novel gastroretentive drug delivery system of gliclazide: hollow beads. Drug Dev Ind Pharm. 1–11.
   Web of Science ®Google Scholar
• Barnett R. 2010. Historical keyword: diabetes. Lancet. 375:191.
   PubMed Web of Science ®Google Scholar
• Bonadonna RC, Cucinotta D, Fedele D, Riccardi G, Tiengo A. 2006. The metabolic syndrome is a risk indicator of microvascular and macrovascular complications in diabetes: results from Metascreen, a multicenter diabetes clinic-based survey. Diabetes Care. 29: 2701–2707.
   PubMed Web of Science ®Google Scholar
• Brand M, Nicholls D. 2011. Assessing mitochondrial dysfunction in cells. Biochem J. 435:297–312.
   PubMed Web of Science ®Google Scholar
• Calasan J, Al-Salami H, Mikov M. 2012. Bile acids and probiotics could help treating diabetes. FEBS J. 279:267–267.
   Web of Science ®Google Scholar
• Chang TM. 1971. The in vivo effects of semipermeable microcapsules containing L-asparaginase on 6C3HED lymphosarcoma. Nature. 229:117–118.
   PubMed Web of Science ®Google Scholar
• Chang TM. 1992. Hybrid artificial cells: microencapsulation of living cells. ASAIO J. 38:128–130.
   PubMedGoogle Scholar
• Chang TM, Johnson LJ, Ransome OJ. 1967. Semipermeable aqueous microcapsules. IV. Nonthrombogenic microcapsules with heparin-complexed membranes. Can J Physiol Pharmacol. 45:705–715.
   PubMed Web of Science ®Google Scholar
• de Vos P., Faas MM, Strand B, Calafiore R. 2006. Alginate-based microcapsules for immunoisolation of pancreatic islets. Biomaterials. 27:5603–5617.
   PubMed Web of Science ®Google Scholar
• de Vos P., Hamel A, Tatarkiewicz K. 2002. Considerations for successful transplantation of encapsulated pancreatic islets. Diabetologia. 45:159–173.
   PubMed Web of Science ®Google Scholar
• Dranka BP, Hill BG, Darley-Usmar VM. 2010. Mitochondrial reserve capacity in endothelial cells: the impact of nitric oxide and reactive oxygen species. Free Radic Biol Med. 48:905–914.
   PubMed Web of Science ®Google Scholar
• Gerencser AA, Neilson A, Choi SW, Edman U, Yadava N, Oh RJ, et al. 2009. Quantitative microplate-based respirometry with correction for oxygen diffusion. Anal Chem. 81:6868–6878.
   PubMed Web of Science ®Google Scholar
• Jiin WY. 2000. Development of new polycations for cell encapsulation with alginate. Mater Sci Eng. 1:59–63.
   Google Scholar
• Kittel A, Falus A, Buzas E. 2013. Microencapsulation technology by nature: Cell derived extracellular vesicles with therapeutic potential. Eur J Microbiol Immunol (Bp). 3:91–96.
   PubMedGoogle Scholar
• Kuhajda K, Kandrac J, Kevresan S, Mikov M, Fawcett JP. 2006. Structure and origin of bile acids: an overview. Eur J Drug Metab Pharmacokinet. 31:135–143.
   PubMed Web of Science ®Google Scholar
• Lalic-Popovic M, Paunkovic J, Grujic Z, Golocorbin-Kon S, Al-Salami H, Mikov M. 2013a. Diabetes and hypertension increase the placental and transcellular permeation of the lipophilic drug diazepam in pregnant women. BMC Pregnancy Childbirth. 13:188.
   PubMed Web of Science ®Google Scholar
• Lalic-Popovic M, Vasovic V, Milijasevic B, Golocorbin-Kon S, Al-Salami H, Mikov M. 2013b. Deoxycholic acid as a modifier of the permeation of gliclazide through the blood brain barrier of a rat. J Diabetes Res. 2013:598603.
   PubMed Web of Science ®Google Scholar
• Maji D. 2004. Prevention of microvascular and macrovascular complications in diabetes mellitus. J Indian Med Assoc. 102: 426, 428, 430 passim.
   PubMedGoogle Scholar
• Malmgren S, Nicholls DG, Taneera J, Bacos K, Koeck T, Tamaddon A, et al. 2009. Tight coupling between glucose and mitochondrial metabolism in clonal β-cells is required for robust insulin secretion. J Biol Chem. 284:32395–32404.
   PubMed Web of Science ®Google Scholar
• Martinez-Moya P, Romero-Calvo I, Requena P, Hernandez-Chirlaque C, Aranda CJ, Gonzalez R, et al. 2013. Dose-dependent antiinflammatory effect of ursodeoxycholic acid in experimental colitis. Int Immunopharmacol. 15:372–380.
   PubMed Web of Science ®Google Scholar
• Mikov, M, Al-Salami H, Golocorbin-Kon G. 2012. Potentials and Limitations of Bile Acids and Probiotics in Diabetes Mellitus. pp. 365–402
   Google Scholar
• Mikov M, Al-Salami H, Golocorbin-Kon S, Skrbic R, Raskovic A, Fawcett JP. 2008. The influence of 3alpha,7alpha-dihydroxy-12-keto-5beta-cholanate on gliclazide pharmacokinetics and glucose levels in a rat model of diabetes. Eur J Drug Metab Pharmacokinet. 33:137–142.
   PubMed Web of Science ®Google Scholar
• Mooranian A, Negrulj R, Arfuso F, Al-Salami H. 2014a. Characterization of a novel bile acid-based delivery platform for microencapsulated pancreatic β-cells. Artif Cells Nanomed Biotechnol. (Epub ahead of print).
   Web of Science ®Google Scholar
• Mooranian A, Negrulj R, Mathavan S, Martinez J, Sciarretta J, Chen-Tan N, et al. 2014b. Stability and release kinetics of an advanced gliclazide-cholic acid formulation: the use of artificial-cell microencapsulation in slow release targeted oral delivery of antidiabetics. J Pharm Innov. 9:150–157.
   PubMed Web of Science ®Google Scholar
• Negrulj R, Mooranian A., Al-Salami H. 2013. Potentials and Limitations of Bile Acids in Type 2 Diabetes Mellitus: Applications of Microencapsulation as a Novel Oral Delivery System. J Endocrinol Diabetes Mellitus. 1:49–59.
   Google Scholar
• Nicholls DG, Darley-Usmar VM, Wu M, Jensen PB, Rogers GW, Ferrick DA. 2010. Bioenergetic profile experiment using C2C12 myoblast cells. J Vis Exp. 46.
   Google Scholar
• Pal D, Nayak AK. 2012. Novel tamarind seed polysaccharide-alginate mucoadhesive microspheres for oral gliclazide delivery: in vitro-in vivo evaluation. Drug Deliv. 19:123–131.
   PubMed Web of Science ®Google Scholar
• Perez MJ, Briz O. 2009. Bile-acid-induced cell injury and protection. World J Gastroenterol. 15:1677–1689.
   PubMed Web of Science ®Google Scholar
• Puri S, Hebrok M. 2012. Diabetic beta Cells: To Be or Not To Be? Cell. 150:1103–4.
   PubMed Web of Science ®Google Scholar
• Rafaelsen OJ. 1964. Glycogen content of rat diaphragm after intraperitoneal injection of insulin and other hormones. Acta Physiol Scand. 61:314–322.
   PubMedGoogle Scholar
• Sherman I, Fisher M. 1986. Hepatic transport of fluorescent molecules: in vivo studies using intravital TV microscopy. Hepatology. 6:444–449.
   PubMed Web of Science ®Google Scholar
• Steele JA, Halle JP, Poncelet D, Neufeld RJ. 2013. Therapeutic cell encapsulation techniques and applications in diabetes. Adv Drug Deliv Rev.
   PubMed Web of Science ®Google Scholar
• Takka S, Cali AG. 2012. Bile salt-reinforced alginate-chitosan beads. Pharm Dev Technol. 17:23–29.
   PubMed Web of Science ®Google Scholar
• Tuch BE, Hughes TC, Evans MD. 2011. Encapsulated pancreatic progenitors derived from human embryonic stem cells as a therapy for insulin-dependent diabetes. Diabetes Metab Res Rev. 27:928–932.
   PubMed Web of Science ®Google Scholar
• Uludag H, Horvath V, Black JP, Sefton MV. 1994. Viability and protein secretion from human Hepatoma (HepG2) cells encapsulated in 400‐μm polyacrylate microcapsules by submerged nozzle–liquid jet extrusion. Biotechnol Bioeng. 44:1199–1204.
   PubMed Web of Science ®Google Scholar
• Uludag H, Sefton MV. 1990. Colorimetric assay for cellular activity in microcapsules. Biomaterials. 11:708–712.
   PubMed Web of Science ®Google Scholar
• Uludag H, Sefton MV. 1992. Metabolic activity of CHO fibroblasts in HEMA–MMA microcapsules. Biotechnol Bioeng. 39:672–678.
   PubMed Web of Science ®Google Scholar
• Whelehan M, Marison IW. 2011. Microencapsulation using vibrating technology. J Microencapsul. 28:669–88.
   PubMed Web of Science ®Google Scholar
• Wikstrom JD, Sereda SB, Stiles L, Elorza A, Allister EM, Neilson A, et al. 2012. A novel high-throughput assay for islet respiration reveals uncoupling of rodent and human islets. PLoS One. 7:e33023.
   PubMed Web of Science ®Google Scholar
• Wu M, Neilson A, Swift AL, Moran R, Tamagnine J, Parslow D, et al. 2007. Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells. Am J Physiol Cell Physiol. 292:C125–C136.
   PubMed Web of Science ®Google Scholar