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Scandinavian Journal of Infectious Diseases Volume 10, 1978 - Issue 2
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Main Article

Pharmacokinetic and Therapeutic Studies of Pivmecillinam in Patients with Normal and Impaired Renal Function

Mats Ekberg Renal Unit of the Department of Internal Medicine, University of Lund, the General Hospital, Malmö, Sweden
,
Torsten Denneberg Renal Unit of the Department of Internal Medicine, University of Lund, the General Hospital, Malmö, Sweden
,
Sture Larsson Department of Infectious Diseases, University of Lund, the General Hospital, Malmö, Sweden
&
Ingmar Juhlin Department of Clinical Bacteriology, University of Lund, the General Hospital, Malmö, Sweden
Pages 127-133 | Published online: 02 Jan 2015

References

  • . Andrews, J., Kendall, M. J. & Mitchard, M.: The disposition of mecillinam and pivmecillinam in man. In: Chemotherapy, 5, p. 167 (ed. J. D. Williams & A. M. Geddes). Plenum Press, New York 1976.
  • . Barlow, A. M.: Nalidixic acid in infections of urinary tract: Laboratory and clinical investigations. Br Med J 2: 1308, 1963.
  • . Brandberg, Å., Herner, B., Swartling, P. G. & Vahlne, G.: Urinvägsinfektion hos den vuxna befolkningen i en svensk stad. Läkartidningen 56: 2655, 1970.
  • . Brown, P. C. C., Donaghy, M. C., Dootson, P. H., Titcombe, D. H. M. & MacLaren, D. M.: Sulphadimidine and nalidixic acid therapy in urinary tract infections in general practice. Practitioner 207: 819, 1971.
  • . Cederberg, Å., Denneberg, T., Ekberg, M. & Juhlin, I.: Nalidixic acid in urinary tract infections with particular reference to the emergence of resistance. Scand J Infect Dis 6: 259, 1974.
  • . Denneberg, T., Ekberg, M. & Juhlin, I.: A new β-lactam antibiotic (FL 1039) in pyelonephritis. 6th International Congress of Nephrology, Firenze (Italy), June 1975.
  • . Engberg-Pedersen, H.: Empirical equation for pharmacokinetic analysis of drug serum levels. Antimicrob Agents Chemother 6: 554, 1974.
  • . Ericsson, H., Högman, C. & Wickman, K.: A paper disc method for determination of bacterial sensitivity to chemotherapeutic and antibiotic agents. Scand J Clin Lab Invest 6: Suppl. 11: 21, 1954.
  • . Leading article. Mecillinam. Lancet 2: 503, 1976.
  • . Lund, F. & Tybring, L.: 6 β-amidinopenicillanic acids–a new group of antibiotics. Nature (New Biol) 236: 135, 1972.
  • . Melchior, N. H., Blom, J., Tybring, L. & Birch-Andersen, A.: Light and electron microscopy of the early response of Escherichia coli to a 6 β-amidinopenicillanic acid (FL 1060). Acta Pathol Microbiol Scand (B) 81: 393, 1973.
  • . Neu, H. C.: Mecillinam, a novel penicillanic acid derivative with unusual activity against gram-negative bacteria. Antimicrob Agents Chemother 9: 793, 1976.
  • . Örsten, P. Å., Bucht, H., Frisch, P. & Henning, C.: Comparison of the effects obtained with sulfonamides, nitrofurantoin and ampicillin in the treatment of recurrent urinary tract infections. Lecture given at the Annual Meeting of the Swedish Medical Association, Stockholm 1968.
  • . Roholt, K., Nielsen, B. & Kristensen, E.: Pharmacokinetic studies with mecillinam and pivmecillinam. Chemotherapy 21: 146, 1975.
  • . Spratt, B. G. & Pardee, A. B.: Penicillin-binding proteins and cell shape in E. coli. Nature 254: 516, 1975.
  • . Thompson, R. E. M. & Rae, J.: Negram (1-ethyl 7-methyl-1,8-naphtyridine-4-one-3-carboxylic acid), a new antibacterial agent for treatment of urinary infection. Report of a trial in general practice. Br J Urol 36: 42, 1964.
  • . Tybring, L.: Mecillinam (FL 1060), a 6 β-amidinopenicillanic acid derivative: In vitro evaluation. Antimicrob Agents Chemother 8: 266, 1975.
  • . Tybring, L. & Melchior, N. H.: Mecillinam susceptibility tests. Comparison of disc diffusion and serial agar dilution tests. To be published.

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