Tissue Distribution of Beta-Lactam Antibiotics: Experimental Studies in Rabbits

References

• Acred, P., Brown, D.M., Clark, B.F. & Mizen, L.: The distribution of antibacterial agents between plasma and lymph in the dog. Br J Pharmacol 39: 439, 1970
   PubMed Web of Science ®Google Scholar
• Alexander, J.W., Sykes, N.S., Mitchell, M.M. & Fisher, M.W.: Concentration of selected intravenously administered antibiotics in experimental surgical wounds. J Trauma 13: 423, 1973
   PubMedGoogle Scholar
• Al-Asadi, M.J.S., Greenwood, D. & O'Grady, F.: In vitro model simulating the form of exposure of bacteria to antimicrobial drugs encountered in infection. Antimicrob Agents Chemother 16: 77, 1979
   PubMedGoogle Scholar
• Barry, A.L.: Procedure for testing antibiotics in agar media: Theoretical considerations. In: Antibiotics in laboratory medicine (ed. V. Lorian). William & Wilkins, Baltimore, 1980, p 1–23
   Google Scholar
• Barza, M. & Weinstein, L.: Some determinants of the distribution of penicillins and cephalosporins in the body. Practical and theoretical considerations. Ann N Y Acad Sci 235: 611, 1974
   Google Scholar
• Barza, M. & Weinstein, L.: Penetration of antibiotics into fibrin loci in vivo. I. Comparison of penetration of ampicillin into fibrin clots, abscesses and “interstitial” fluids. J Infect Dis 129: 59, 1974
   PubMed Web of Science ®Google Scholar
• Batchelor, F.R., Doyle, F.P., Nayler, J.H.C. & Rolinson, G.N.: Synthesis of penicillin: 6-aminopenicillanic acid in penicillin fermentations. Nature 183: 257, 1959
   PubMed Web of Science ®Google Scholar
• Bergan, T.: Kinetics of tissue penetration. Scand J Infect Dis Suppl 14: 36, 1978
   Google Scholar
• Bergan, T., Carlsen, I.B. & Fugelsang, J.E.: An in vitro model for monitoring bacterial responses to antibiotic agents under simulated in vivo conditions. Infection 8: Suppl 1: 96, 1980
   Web of Science ®Google Scholar
• Bergeron, M.G.: A review of models for the therapy of experimental infections. Scand J Infect Dis Suppl 14: 189, 1978
   Google Scholar
• Bergström, J.: Muscle electrolytes in man. Scand J Clin Lab Invest 14: Suppl 68: 11, 1962
   PubMed Web of Science ®Google Scholar
• Bill, A.: Plasma protein dynamics: Albumin and IgG capillary permeability, extravascular movement and regional blood flow in unanesthetized rabbits. Acta Physiol Scand 101: 28, 1977
   PubMedGoogle Scholar
• Bill, A.: Regional lymph flow in unanesthetized rabbits. Uppsala J Med Sci 84: 129, 1979
   PubMed Web of Science ®Google Scholar
• Bird, A.E. & Marshall, A.C.: Correlation of serum binding of penicillins with partition coefficients. Biochemical Pharmacol 16: 2275, 1967
   PubMed Web of Science ®Google Scholar
• Brown, K.N. & Percival, A.: Penetration of antimicrobials into tissue culture cells and leucocytes. Scand J Infect Dis Suppl 14: 251, 1978
   Google Scholar
• Carbon, C., Phong Chau, N., Contrepois, A., & Lamotte-Barrillon, S.: Tissue cage experiments with β-lactam antibiotics in rabbits. Scand J Infect Dis, Suppl 14: 127, 1973
   Google Scholar
• Chisholm, G.D., Smith, C.B., Waterworth, P.M. & Calnan, J.S.: Factors influencing the distribution of antibacterial agents in interstitial tissue fluid: Molecular size and protein binding. Infection Suppl 2: 123, 1976
   Google Scholar
• Chisholm, G.D., Waterworth, P.M., Calnan, J.S. & Garrod, L.P.: Concentration of antibacterial agents in interstitial tissue fluid. Brit Med J 1: 569, 1973
   PubMed Web of Science ®Google Scholar
• Craig, W.A. & Suh, B.: Theory and practical impact of binding of antimicrobials to serum proteins and tissue. Scand J Infect Dis Suppl 14: 92, 1978
   Google Scholar
• Craig, W.A. & Welling, P.G.: Protein binding of antimicrobials: Clinical pharmacokinetic and therapeutic implications. Clinical Pharmacokinetics 2: 252, 1977
   PubMed Web of Science ®Google Scholar
• Dornbusch, K.: Antibiotics in bone tissues. Methodological and practical aspects. Scand J Infect Dis Suppl 14: 177, 1978
   Google Scholar
• Eagle, H., Fleischman, R. & Levy, M.: “Continuous” vs “discontinuous” therapy with penicillin. The effect of the interval between injections on therapeutic efficacy. New Engl J Med 248: 481, 1953
   PubMed Web of Science ®Google Scholar
• Eickenberg, H.-U.: Interstitial concentration of antibiotics and their significance for an adequate dosage. Infection 8: Suppl 1: 39, 1980
   Google Scholar
• Fleming, A.: On the antibacterial action of cultures of a penicillum, with special reference to their use in the isolation of B. influenzae. Brit J Exp Path 10: 226, 1929
   Google Scholar
• Florey, M.E., Turton, E.C. & Duthie, E.S.: Penicillin in wound exudates. Lancet 2: 405, 1946
   PubMedGoogle Scholar
• Gerber, A.U. & Craig, W.A.: Growth kinetics of respiratory pathogens after short exposures to ampicillin and erythromycin in vitro. J Antimicr Chemother 1981 (in press)
   Google Scholar
• Gerding, D.N., Peterson, L.R., Salomonson, J.K., Hall, W.H. & Schierl, E.A.: Prediction of the concentration of penicillins in ascitic fluid from serum kinetics and protein binding of antibiotics in serum and ascitic fluid of dogs. J Infect Dis 138: 166, 1973
   Google Scholar
• Gibaldi, M. & Perrier, D.: Pharmacokinetics. M. Dekker, Inc., New York 1975, p 45
   Google Scholar
• Gillett, A.P. & Wise, R.: Penetration of four cephalosporins into tissue fluid in man. Lancet 1: 962, 1978
   PubMed Web of Science ®Google Scholar
• Grasso, S., Meinardi, G., de Carneri, I. & Tamassia, V.: New in vitro model to study the effect of antibiotic concentration and rate of elimination on antibacterial activity. Antimicrob Agents Chemother 13: 570, 1978
   PubMed Web of Science ®Google Scholar
• Guyton, A.C.: Textbook of medical physiology. W.B. Saunders Company, 1978, p 370–371
   Google Scholar
• Hogben, C.A.M.: Biological membranes and their passage by drugs. In: Handbook of experimental pharmacology (eds. B.B. Brodie & J.R. Gilette). Springer-Verlag, New York, 1971, p 1–8
   Google Scholar
• Holm, S.E.: Experimental models for studies on transportation of antibiotics to extravasal compartments. Scand J Infect Dis Suppl 13: 47, 1978
   Google Scholar
• Holm, S.E., Ekedahl, C. & Bergholm, A.-M.: Comparison of antibiotic assays using different experimental models and their possible clinical significance. Scand J Infect Dis Suppl 14: 214, 1973
   Google Scholar
• Hou, J.P. & Poole, J.W.: β-lactam antibiotics: Their physicochemical properties and biological activities in relation to structure. J Pharm Sci 60: 503, 1971
   PubMed Web of Science ®Google Scholar
• Howell, A., Sutherland, R. & Rolinson, G.N.: Effect of protein binding on levels of ampicillin and cloxacillin in synovial fluid. Clin Pharmacol Ther 13: 724, 1972
   PubMed Web of Science ®Google Scholar
• Jalling, B., Malmborg, A.-S., Lindman, A. & Boréus, L.O.: Evaluation of a micromethod for determination of antibiotic concentrations in plasma. Europ J Clin Pharmacol 4: 150, 1972
   PubMed Web of Science ®Google Scholar
• Kaplan, J.M., Mc Cracken Jr., H. & Snyder, E.: Influence of methodology upon apparent concentrations of antibiotics in tissue. Antimicrob Agents Chemother 3: 143, 1973
   PubMed Web of Science ®Google Scholar
• Kunin, C.M., Craig, W.A., Kornguth, M. & Monson, R.: Influence of binding on the pharmacologic activity of antibiotics. Ann N Y Acad Sci 226: 214, 1973
   PubMedGoogle Scholar
• Kunst, M.W. & Mattie, H.: Cefazolin and cephradine: Relationship between serum concentrations and tissue contents in mice. Infection 5: 166, 1978
   Google Scholar
• Laber, G., Obenaus, H. & Walzl, H.: Pressure measurements and histological investigations after subcutaneous implantation of diffusion chambers in rabbits. Infection 8: 187, 1980
   Google Scholar
• Laber, G., Schütze, E., Leskova, R., Kolb, R. & Georgopoulos, A.: A diffusion chamber technique for measuring concentrations of antibiotics in interstitial fluid. Infection 8: 53, 1980
   Google Scholar
• Linglöf, T.O., Cars, O. & Nordbring, F.: Piperacillin in the treatment of severe infections: Clinical evaluation and pharmacokinetics in serum, wound fluid and subcutaneous tissue. Proceedings of the 11th international congress of chemotherapy and the 19th interscience conference on antimicrobial agents and chemotherapy 1980, p 287
   Google Scholar
• Lode, H., Gruhlke, G., Hallermann, W. & Dzwillo, G.: Significance of pleural and sputum concentrations for antibiotic therapy of bronchopulmonary infections. Infection 8: Suppl 1: 49, 1980
   Google Scholar
• de Louvois, J. & Hurley, R.: Inactivation of penicillin by purulent exudates. Brit Med J 1: 998, 1977
   PubMed Web of Science ®Google Scholar
• Lundberg, C. & Malmborg, A.-S.: Concentration of penicillin V and tetracycline in maxillary sinus secretion after repeated doses. Scand J Infect Dis 5: 123, 1973
   PubMedGoogle Scholar
• Mandell, G.L.: Interaction of intraleukocytic bacteria and antibiotics. J Clin Invest 52: 1673, 1973
   PubMed Web of Science ®Google Scholar
• Mannheimer, C. & Brorson, J.-E.: Tissue concentrations of antibiotics. J Antimicrob Chemother 2: 313, 1976
   PubMedGoogle Scholar
• Muggleton, P.W., Ryan, D.M. & Foord, R.D.: A laboratory investigation of the treatment of renal infections with cephaloridine. Abstracts from the 5th international congress of chemotherapy, Vienna, 1967
   Google Scholar
• Odar-Cederlöf, I. & Borgå, O.: Impaired plasma protein binding of phenytoin in uremia and displacement effect of salicylic acid. Clin Pharmacol Therap 20: 36, 1976
   PubMedGoogle Scholar
• O'Keefe, J.P., Tally, F.P., Barza, M. & Gorbach, S.L.: Inactivation of penicillin G during experimental infection with Bacteroides fragilis. J Infect Dis 137: 437, 1978
   PubMed Web of Science ®Google Scholar
• Peterson, L.R. & Gerding, D.N.: Prediction of cefazolin penetration into high- and low-protein-containing extravascular fluid: New method for performing simultaneous studies. Antimicrob Agents Chemother 14: 533, 1978
   PubMedGoogle Scholar
• Peterson, L.R. & Gerding, D.N.: Influence of protein binding of antibiotics on serum pharmacokinetics and extravascular penetration: Clinically useful concepts. Rev Infect Dis 2: 340, 1980
   PubMedGoogle Scholar
• Peterson, L.R., Gerding, D.N., McLinn, D. & Hall, W.H.: Prediction of peak penicillin and cephalosporin concentrations in canine serum as derived from in vitro serum and tissue quantitative protein binding. J Antimicrob Chemother 5: 219, 1979
   PubMedGoogle Scholar
• Raeburn, J.A.: A review of experimental models for studying the tissue penetration of antibiotics in man. Scand J Infect Dis Suppl 14: 225, 1978
   Google Scholar
• Reeve, E.B.: Interstitial albumin. In: Albumin structure, function and uses (eds. V.M. Rosenoer, M. Oratz and M.A. Rothschild). Pergamon Press, Oxford, 1977, p 283–303
   Google Scholar
• Rolinson, G.N.: 6-APA and the development of the β-lactam antibiotics. J Antimicrob Chemother 5: 7, 1979
   PubMed Web of Science ®Google Scholar
• Rolinson, G.N.: The significance of protein binding of antibiotics in antibacterial chemotherapy. J Antimicrob Chemother 6: 311, 1980
   PubMed Web of Science ®Google Scholar
• Rolinson, G.N.: Basis and results of therapy with β-lactam antibiotics in experimental infections. Infection 8: Suppl 1: 30, 1980
   Google Scholar
• Rolinson, G.N. & Sutherland, R.: The binding of antibiotics to serum proteins. Brit J Pharmacol 25: 638, 1965
   PubMed Web of Science ®Google Scholar
• Rothschild, M.A., Oratz, M. & Schreiber, S.S.: Extravascular albumin. N Engl J Med 301: 497, 1979
   PubMedGoogle Scholar
• Rutili, G.: Personal communication, 1979
   Google Scholar
• Rutili, G. & Arfors, K.-E.: Fluorescein labelled dextran measurement in interstitial fluid in studies of macromolecular permeability. Microvasc Res 12: 221, 1976
   PubMedGoogle Scholar
• Ryan, D.M.: Implanted tissue cages: A critical evaluation of their relevance in measuring tissue concentrations of antibiotics. Scand J Infect Dis Suppl 13: 58, 1978
   Google Scholar
• Ryan, D.M.: Implanted cotton threads: A novel method for measuring concentrations of antibiotics in tissue fluid. J Antimicrob Chemother 5: 735, 1979
   PubMedGoogle Scholar
• Ryan, D.M., O'Callaghan, H. & Muggleton, P.W.: Cefuroxime, a new cephalosporin antibiotic: Activity in vivo. Antimicr Agents Chemother 9: 520, 1976
   PubMedGoogle Scholar
• Ryan, D.M. & Mason, U.: Antibiotic tissue levels: Are tissue cages relevant for their measurement? J Antimicrob Chemother 5: 116, 1979
   PubMedGoogle Scholar
• Rylander, M., Holm, S.E., Norrby, R. & Brorson, J.-E.: Studies on the pharmacokinetics of cefoxitin, cefuroxime, cephaloridine and cephalotin using subcutaneous tissue cages. Scand J Infect Dis Suppl 13: 52, 1978
   Google Scholar
• Rylander, M., Mannheimer, C. & Brorson, J.-E.: Penetration of cephradine and cefazolin into ulcers of patients suffering from peripheral arterial circulatory insufficiency. Scand J Infect Dis 11: 281, 1979
   PubMed Web of Science ®Google Scholar
• Schreiner, A., Hellum, K.B., Digranes, A. & Bergman, I.: Transfer of penicillin G and ampicillin into human skin blisters induced by suction. Scand J Infect Dis Suppl 14: 233, 1978
   Google Scholar
• Singhivi, S.M., Heald, A.F. & Schreiber, E.C.: Pharmacokinetics of cephalosporin antibiotics: Protein binding considerations. Chemotherapy 24: 121, 1978
   PubMedGoogle Scholar
• Simon, C.: Antibiotikaspiegel in Serum, Speichel, Tränen- und Hautblasenflüssigkeit. Infection 4: Suppl 2: 91, 1976
   Google Scholar
• Sjöqvist, F., Borgå, O. & Orme, M. L'E.: Fundamentals of clinical pharmacology. In: Drug treatment (ed. G.S. Avery), Adis press, Sidney, 1976, p 1–42
   Google Scholar
• Stille, W.: Dose-activity relationships in chemotherapy. Infection 8: Suppl 1: 14, 1980
   Google Scholar
• Symposium on tissue penetration of antibiotics. Scand J Infect Dis Suppl 14, 1978
   Google Scholar
• Ullberg, S.: Studies on the distribution and fate of S35-labelled benzylpenicillin in the body. Acta Radiologica Suppl 118, 1954
   Google Scholar
• Ungar, J.: Penicillin in tissue exudates after injection. Lancet 1: 56, 1950
   PubMedGoogle Scholar
• Tan, J.S., Bannister, T. & Phair, J.: Levels of amoxicillin and ampicillin in human serum and interstitial fluid. J Infect Dis 129: Suppl: 146, 1974
   Google Scholar
• Tan, J.S. & Salstrom, S.-J.: Bacampicillin, ampicillin, cephalotin and cephapirin levels in human blood and interstitial fluid. Antimicr Agents Chemother 15: 510, 1979
   PubMedGoogle Scholar
• Tan, J.S., Trott, A., Phair, J.P. & Watanakunakorn, C.: A method for measurement of antibiotics in human interstitial fluid. J Infect Dis 126: 492, 1972
   PubMed Web of Science ®Google Scholar
• Tight, R.R. & White, A.C.: Serum and subcutaneous chamber fluid dynamics of penicillins after single large parenteral doses. Antimicr Agents Chemother 17: 229, 1980
   PubMedGoogle Scholar
• Weinstein, L., Daikos, G.K., Perrin, T.S.: Studies on the relationship of tissue fluid and blood levels of penicillin. J Lab Clin Med 38: 712, 1951
   PubMed Web of Science ®Google Scholar
• Wiedemann, B.: Microbiological basis of antibiotic therapy. Infection 8: Suppl 1: 6, 1980
   Google Scholar
• Wise, R., Cadge, B., Gillett, A.P. & Bhamjee, A.: The pharmacology of cefoxitin and the comparison of two human tissue models. J Infect 1: Suppl 1: 49, 1979
   Google Scholar
• Wise, R., Gillett, A.P., Cadge, B., Durham, S.R. & Baker, S.: The influence of protein binding upon tissue fluid levels of six β-lactam antibiotics. J Infect Dis 142: 77, 1980
   PubMed Web of Science ®Google Scholar