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Modern Rheumatology Volume 18, 2008 - Issue 3
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Case Report

Reversible infliximab-related lymphoproliferative disorder associated with Epstein-Barr virus in a patient with rheumatoid arthritis

Atsushi KomatsudaThird Department of Internal Medicine, Akita University School of Medicine, 1-1-1 Hondo, Akita 010-8543, JapanCorrespondence[email protected]
,
Hideki WakuiThird Department of Internal Medicine, Akita University School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan
,
Takashi NimuraDepartment of Internal Medicine, Senboku General Hospital, Daisen, Japan
&
Ken-ichi SawadaThird Department of Internal Medicine, Akita University School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan
Pages 315-318 | Received 07 Dec 2007, Accepted 01 Feb 2008, Published online: 02 Jan 2014

References

  • Ekström K, Hjalgrim H, Brandt L, Baecklund E, Klareskog L, Ekbom A et al. Risk of malignant lymphomas in patients with rheumatoid arthritis and in their first-degree relatives. Arthritis Rheum. 2003;48:963–70.
  • Baecklund E, Iliadou A, Askling J, Ekbom A, Backlin C, Granath F et al. Association of chronic inflammation, not its treatment, with increased lymphoma risk in rheumatoid arthritis. Arthritis Rheum. 2006;54:692–701.
  • Wolfe F, Michaud K. Lymphoma in rheumatoid arthritis: the effect of methotrexate and anti-tumor necrosis factor therapy in 18,572 patients. Arthritis Rheum. 2004;50:1740–51.
  • Harris NL, Swerdlow SH. Immunodeficiency associated lym-phoproliferative disorders. In: Jaffe ES, Harris NL, Stein H, Vardiman JW, editors. World Health Organization classification of tumours: pathology and genetics of tumours of haematopoietic and lymphoid tissues. Lyon: IARC Press; 2001. p. 255–71.
  • Brown SL, Greene MH, Gershon SK, Edwards ET, Braun MM. Tumor necrosis factor antagonist therapy and lymphoma devel-opment: 26 cases reported to the Food and Drug Administration. Arthritis Rheum. 2002;46: 3151–8.
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  • Baecklund E, Sundström C, Ekbom A, Catrina AT, Biberfeld P, Feltelius N, et al. Lymphoma subtypes in patients with rheuma-toid arthritis. Increased proportion of diffuse large B cell lymphoma. Arthritis Rheum. 2003;48:1543–50.
  • Kamel OW, van de Rijn M, Weiss LM, Del Zoppo JD, Hench PK, Robbins BA, et al. Reversible lymphomas associated with Epstein-Barr virus occurring during methotrexate therapy for rheumatoid arthritis and dermatomyositis. N Engl J Med. 1993;328:1317–21.
  • Hoshida Y, Yamamoto S, Wada N, Xu J-X, Sasaki T, Aozasa K. Infliximab-associated lymphoproliferative disorders. Int J Hematol. 2005;81:356-7 (letter).
  • Oyama T, Ichimura K, Suzuki R, Suzumiya J, Ohshima K, Yatabe Y, et al. Senile EBV+ B-cell lymphoproliferative disor-ders: a clinicopathologic study of 22 patients. Am J Surg Pathol. 2003;27:16–26.

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