Smoking is associated with an increased risk of developing ACPA-positive but not ACPA-negative rheumatoid arthritis in Asian populations: evidence from the Malaysian MyEIRA case–control study

References

• Klareskog L, Catrina AT, Paget S. Rheumatoid arthritis. Lancet. 2009;373:659–72.
   Google Scholar
• Scott DL, Wolfe F, Huizinga TW. Rheumatoid arthritis. Lancet. 2010;376:1094–108.
   Google Scholar
• Jarvinen P, Aho K. Twin studies in rheumatic diseases. Semin Arthritis Rheum. 1994;24:19–28.
   PubMed Web of Science ®Google Scholar
• Padyukov L, Silva C, Stolt P, Alfredsson L, Klareskog L. A gene-environment interaction between smoking and shared epitope genes in HLA-DR provides a high risk of seropositive rheumatoid arthritis. Arthritis Rheum. 2004;50:3085–92.
   Google Scholar
• Klareskog L, Stolt P, Lundberg K, Kallberg H, Bengtsson C, Grunewald J, et al. A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrul-fination. Arthritis Rheum. 2006;54:38–46.
   PubMed Web of Science ®Google Scholar
• Stolt P, Bengtsson C, Nordmark B, Lindblad S, Lundberg I, Klareskog L, et al. Quantification of the influence of cigarette smoking on rheumatoid arthritis: results from a population based case-control study, using incident cases. Ann Rheum Dis. 2003;62:835–41.
   PubMed Web of Science ®Google Scholar
• Kallberg H, Jacobsen S, Bengtsson C, Pedersen M, Padyukov L, Gaffed P, et al. Alcohol consumption is associated with decreased risk of rheumatoid arthritis: results from two Scandinavian case-control studies. Ann Rheum Dis. 2009;68:222–7.
   PubMed Web of Science ®Google Scholar
• Karlson EW, Chang SC, Cui J, Chibnik LB, Fraser PA, De Vivo I, et al. Gene-environment interaction between HLA-DRB1 shared epitope and heavy cigarette smoking in predicting incident rheumatoid arthritis. Ann Rheum Dis. 2010;69: 54–60.
   Google Scholar
• Aho K, Koskenvuo M, Tuominen J, Kaprio J. Occurrence of rheumatoid arthritis in a nationwide series of twins. J Rheumatol. 1986;13:899–902.
   PubMed Web of Science ®Google Scholar
• Silman AJ, MacGregor AJ, Thomson W, Holligan S, Carthy D, Farhan A, et al. Twin concordance rates for rheumatoid arthritis: results from a nationwide study. Br J Rheumatol. 1993;32:903–7.
   PubMedGoogle Scholar
• MacGregor AJ, Snieder H, Rigby AS, Koskenvuo M, Kaprio Aho K, et al. Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins. Arthritis Rheum. 2000;43:30–7.
   PubMed Web of Science ®Google Scholar
• Vessey MP, Villard-Mackintosh L, Yeates D. Oral contracep-tives, cigarette smoking and other factors in relation to arthritis. Contraception. 1987;35:457–64.
   PubMed Web of Science ®Google Scholar
• Uhfig T, Hagen KB, Kvien TK. Current tobacco smoking, formal education, and the risk of rheumatoid arthritis. J Rheumatol. 1999;26:47–54.
   Google Scholar
• Klareskog L, Alfredsson L, Rantapaa-Dahlqvist S, Berglin E, Stolt P, Padyukov L. What precedes development of rheumatoid arthritis? Ann Rheum Dis. 2004;63\(Suppl 2):ii28–31.
   Google Scholar
• Lundstrom E, Kallberg H, Alfredsson L, Klareskog L, Padyukov L. Gene-environment interaction between the DRB1 shared epi-tope and smoking in the risk of anti-citrullinated protein anti-body-positive rheumatoid arthritis: all alleles are important. Arthritis Rheum. 2009;60: 1597–603.
   Google Scholar
• Pedersen M, Jacobsen S, Klarlund M, Pedersen BV, Wiik A, Wohlfahrt J, et al. Environmental risk factors differ between rheumatoid arthritis with and without auto-antibodies against cyclic citrullinated peptides. Arthritis Res Ther. 2006;8:R133.
   PubMed Web of Science ®Google Scholar
• Linn-Rasker SP, n Mil AH, van Gaalen FA, Kloppenburg M, de Vries RR, le Cessie S, et al. Smoking is a risk factor for anti-CCP antibodies only in rheumatoid arthritis patients who carry HLA-DRB1 shared epitope alleles. Ann Rheum Dis. 2006;65: 366–71.
   Google Scholar
• Michou L, Teixeira VH, Pierlot C, Lasbleiz S, Bardin T, Dieude P, et al. Associations between genetic factors, tobacco smoking and autoantibodies in familial and sporadic rheumatoid arthritis. Ann Rheum Dis. 2008;67:466–70.
   PubMed Web of Science ®Google Scholar
• Pedersen M, Jacobsen S, Gaffed P, Madsen HO, Klarlund M, Svejgaard A, et al. Strong combined gene-environment effects in anti-cyclic citrullinated peptide-positive rheumatoid arthritis: a nationwide case-control study in Denmark. Arthritis Rheum. 2007;56:1446–53.
   PubMed Web of Science ®Google Scholar
• Morgan AW, Thomson W, Martin SG, Carter AM, Erlich HA, Barton A, et al. Reevaluation of the interaction between HLA-DRB1 shared epitope alleles, PTPN22, and smoking in deter-mining susceptibility to autoantibody-positive and autoantibody-negative rheumatoid arthritis in a large UK Caucasian population. Arthritis Rheum. 2009;60:2565–76.
   PubMed Web of Science ®Google Scholar
• Bang SY, Lee KH, Cho SK, Lee HS, Lee KW, Bae SC. Smoking increases rheumatoid arthritis susceptibility in individuals carry-ing the HLA-DRB1 shared epitope, regardless of rheumatoid factor or anti-cyclic citrullinated peptide antibody status. Arthritis Rheum. 2010;62:369–77.
   PubMed Web of Science ®Google Scholar
• Kallberg H, Ding B, Padyukov L, Bengtsson C, Ronnelid J, Klareskog L, et al. Smoking is a major preventable risk factor for rheumatoid arthritis: estimations of risks after various exposures to cigarette smoke. Ann Rheum Dis. 2011;70:508–11.
   PubMed Web of Science ®Google Scholar
• Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 1988;31:315–24.
   PubMed Web of Science ®Google Scholar
• Agresti A. Categorical data analysis. Wiley series in probability and mathematical statistics. Applied probability and statistics. Wiley, New York; 1990. p. 100–1.
   Google Scholar
• Kong KF, Yeap SS, Chow SK, Phipps ME. HLA-DRB1 genes and susceptibility to rheumatoid arthritis in three ethnic groups from Malaysia. Autoimmunity. 2002;35:235–9.
   PubMed Web of Science ®Google Scholar
• Institute for Public Health (IPH). The Third National Health and Morbidity Survey (NHMS III) 2006, Smoking. Malaysia: Min-istry of Health; 2008.
   Google Scholar
• Sugiyama D, Nishimura K, Tamaki K, Tsuji G, Nakazawa T, Morinobu A, et al. Impact of smoking as a risk factor for developing rheumatoid arthritis: a meta-analysis of observational studies. Ann Rheum Dis. 2010;69:70–81.
   PubMed Web of Science ®Google Scholar