Expression of CD44 in articular cartilage is associated with disease severity in knee osteoarthritis

References

• Knudson W, Aguiar DJ, Hua Q, Knudson CB. CD44-anchored hyaluronan-rich pericellular matrices: an ultrastructural and biochemical analysis. Exp Cell Res. 1996; 228(2): 216–228.
   PubMedGoogle Scholar
• Screaton GR, Bell MV, Jackson DG, Cornelis FB, Gerth U, Bell JI. Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons. Proc Natl Acad Sci USA. 1992; 89(24): 12160–12164.
   PubMedGoogle Scholar
• Naor D, Wallach-Dayan SB, Zahalka MA, Sionov RV. Involvement of CD44, a molecule with a thousand faces, in cancer dissemination. Semin Cancer Biol. 2008; 18(4): 260–267.
   PubMedGoogle Scholar
• Bajorath J. Molecular organization, structural features, and ligand binding characteristics of CD44, a highly variable cell surface glycoprotein with multiple functions. Proteins. 2000; 39(2): 103–111.
   PubMedGoogle Scholar
• Hale LP, Haynes BF, McCachren SS. Expression of CD44 variants in human inflammatory synovitis. J Clin Immunol. 1995; 15(6): 300–311.
   PubMedGoogle Scholar
• Cooper DL, Dougherty GJ. To metastasize or not? Selection of CD44 splice sites. Nat Med. 1995; 1(7): 635–637.
   PubMedGoogle Scholar
• Tölg C, Hofmann M, Herrlich P, Ponta H. Splicing choice from ten variant exons establishes CD44 variability. Nucleic Acids Res. 1993; 21(5): 1225–1229.
   PubMedGoogle Scholar
• Underhill C. CD44: the hyaluronan receptor. J Cell Sci. 1992;103 Pt 2:293–8.
   PubMedGoogle Scholar
• Weber GF, Ashkar S, Glimcher MJ, Cantor H. Receptor–ligand interaction between CD44 and osteopontin (Eta-1). Science. 1996; 271(5248): 509–512.
   PubMedGoogle Scholar
• Ishii S, Ford R, Thomas P, Nachman A, Steele G Jr. Jessup JM.CD44 participates in the adhesion of human colorectal carcinoma cells to laminin and type IV collagen. Surg Oncol. 1993; 2(4): 255–264.
   PubMedGoogle Scholar
• Jalkanen S, Jalkanen M. Lymphocyte CD44 binds the COOH-terminal heparin-binding domain of fibronectin. J Cell Biol. 1992; 116(3): 817–825.
   PubMedGoogle Scholar
• Salter DM, Godolphin JL, Gourlay MS, Lawson MF, Hughes DE, Dunne E. Analysis of human articular chondrocyte CD44 isoform expression and function in health and disease. J Pathol. 1996; 179(4): 396–402.
   PubMedGoogle Scholar
• Tibesku CO, Szuwart T, Ocken SA, Skwara A, Fuchs S. Increase in the expression of the transmembrane surface receptor CD44v6 on chondrocytes in animals with osteoarthritis. Arthritis Rheum. 2005; 52(3): 810–817.
   PubMedGoogle Scholar
• Chow G, Nietfeld JJ, Knudson CB, Knudson W. Antisense inhibition of chondrocyte CD44 expression leading to cartilage chondrolysis. Arthritis Rheum. 1998; 41(8): 1411–1419.
   PubMedGoogle Scholar
• Sluijs JA, Geesink RG, Linden AJ, Bulstra SK, Kuyer R, Drukker J. The reliability of the Mankin score for osteoarthritis. J Orthop Res. 1992; 10(1): 58–61.
   PubMedGoogle Scholar
• Dunn S, Kolomytkin OV, Waddell DD, Marino AA. Hyaluronan-binding receptors: possible involvement in osteoarthritis. Mod Rheumatol. 2009; 19(2): 151–155.
   PubMedGoogle Scholar
• Fuchs S, Dankbar B, Wildenau G, Goetz W, Lohmann CH, Tibesku CO. Expression of the CD44 variant isoform 5 in the human osteoarthritic knee joint: correlation with radiological, histomorphological, and biochemical parameters. J Orthop Res. 2004; 22(4): 774–780.
   PubMedGoogle Scholar
• Chow G, Knudson CB, Homandberg G, Knudson W. Increased expression of CD44 in bovine articular chondrocytes by catabolic cellular mediators. J Biol Chem. 1995; 270(46): 27734–27741.
   PubMedGoogle Scholar
• Nishida Y, D’Souza AL, Thonar EJ, Knudson W. Stimulation of hyaluronan metabolism by interleukin-1alpha in human articular cartilage. Arthritis Rheum. 2000; 43(6): 1315–1326.
   PubMedGoogle Scholar
• Knudson W, Loeser RF. CD44 and integrin matrix receptors participate in cartilage homeostasis. Cell Mol Life Sci. 2002; 59(1): 36–44.
   PubMedGoogle Scholar
• Knudson CB, Nofal GA, Pamintuan L, Aguiar DJ. The chondrocyte pericellular matrix: a model for hyaluronan-mediated cell–matrix interactions. Biochem Soc Trans. 1999; 27(2): 142–147.
   PubMedGoogle Scholar
• Hua Q, Knudson CB, Knudson W. Internalization of hyaluronan by chondrocytes occurs via receptor-mediated endocytosis. J Cell Sci. 1993; 106Pt 1365–375.
   PubMedGoogle Scholar
• Embry JJ, Knudson W. G1 domain of aggrecan cointernalizes with hyaluronan via a CD44-mediated mechanism in bovine articular chondrocytes. Arthritis Rheum. 2003; 48(12): 3431–3441.
   PubMedGoogle Scholar
• Isacke CM. The role of the cytoplasmic domain in regulating CD44 function. J Cell Sci. 1994; 107Pt 92353–2359.
   PubMedGoogle Scholar
• Lokeshwar VB, Fregien N, Bourguignon LY. Ankyrin-binding domain of CD44(GP85) is required for the expression of hyaluronic acid-mediated adhesion function. J Cell Biol. 1994; 126(4): 1099–1109.
   PubMedGoogle Scholar
• Tsukita S, Oishi K, Sato N, Sagara J, Kawai A, Tsukita S. ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons. J Cell Biol. 1994; 126(2): 391–401.
   PubMedGoogle Scholar
• Yasuda T. Activation of Akt leading to NF-κB up-regulation in chondrocytes stimulated with fibronectin fragment. Biomed Res. 2011; 32(3): 209–215.
   PubMedGoogle Scholar
• Yasuda T, Poole AR, Shimizu M, Nakagawa T, Julovi SM, Tamamura H, et al. Involvement of CD44 in induction of matrix metalloproteinases by a COOH-terminal heparin-binding fragment of fibronectin in human articular cartilage in culture. Arthritis Rheum. 2003; 48(5): 1271–1280.
   PubMedGoogle Scholar
• Larkin J, Renukaradhya GJ, Sriram V, Du W, Gervay-Hague J, Brutkiewicz RR. CD44 differentially activates mouse NK T cells and conventional T cells. J Immunol. 2006; 177(1): 268–279.
   PubMedGoogle Scholar
• Clark RA, Alon R, Springer TA. CD44 and hyaluronan-dependent rolling interactions of lymphocytes on tonsillar stroma. J Cell Biol. 1996; 134(4): 1075–1087.
   PubMedGoogle Scholar
• Motte CA, Hascall VC, Drazba J, Bandyopadhyay SK, Strong SA. Mononuclear leukocytes bind to specific hyaluronan structures on colon mucosal smooth muscle cells treated with polyinosinic acid: polycytidylic acid: inter-alpha-trypsin inhibitor is crucial to structure and function. Am J Pathol. 2003; 163(1): 121–133.
   PubMedGoogle Scholar
• Mori H, Tomari T, Koshikawa N, Kajita M, Itoh Y, Sato H, et al. CD44 directs membrane-type 1 matrix metalloproteinase to lamellipodia by associating with its hemopexin-like domain. EMBO J. 2002; 21(15): 3949–3959.
   PubMedGoogle Scholar
• Mikecz K, Dennis K, Shi M, Kim JH. Modulation of hyaluronan receptor (CD44) function in vivo in a murine model of rheumatoid arthritis. Arthritis Rheum. 1999; 42(4): 659–668.
   PubMedGoogle Scholar
• Neidhart M, Gay RE, Gay S. Anti-interleukin-1 and anti-CD44 interventions producing significant inhibition of cartilage destruction in an in vitro model of cartilage invasion by rheumatoid arthritis synovial fibroblasts. Arthritis Rheum. 2000; 43(8): 1719–1728.
   PubMedGoogle Scholar
• Sato MI, Koshino T. Takagi T.CD44 expression on chondrocytes in knees of DBA/1 mice with type II collagen-induced arthritis. Clin Exp Rheumatol. 1999; 17(2): 185–190.
   PubMedGoogle Scholar