5
Views
0
CrossRef citations to date
0
Altmetric
REVIEW ARTICLE

Gene therapy for arthritis

Pages 78-82 | Received 21 Feb 2000, Published online: 02 Jan 2014

References

  • Tomita T, Hashimoto H, Tomita N, Morishita R, Lee SB, Hayashida K, et al. In vivo direct gene transfer into articular cartilage by intraarticular injection mediated by HVJ (Sendai virus) and liposomes. Arthritis Rheum 1997;40:901–6.
  • Tomita T, Takeuchi E, Tomita N, Morishita R, Kaneko M, Yamamoto K, et al. Suppressed severity of collagen-induced arthritis by in vivo transfection of nuclear factor kB decoy oligonucleotides as a gene therapy. Arthritis Rheum 1999;42:2532–42.
  • Miyasaka N, Sato K, Goto M, Sasano M, Natsuyama M, Inoue K, et al. Augmented interleukin-1 production and HLA-DR ex-pression in the synovium of rheumatoid arthritis patients. Possible involvement in joint destruction. Arthritis Rheum 1988;31:480–
  • Whalen JD, Lechman EL, Carlos CA, Weiss K, Kovesdi I, Glorioso JC, et al. Adenoviral transfer of the viral IL-10 gene periarticularly to mouse paws suppresses development of collagen-induced arthritis in both injected and uninjected paws. J Immunol 1999;162:3625–32.
  • Makarov SS, Olsen JC, Johnston WN, Anderle SK, Brown RR, Baldwin AJ, et al. Suppression of experimental arthritis by gene transfer of interleukin-1 receptor antagonist cDNA. Proc Natl Acad Sci USA 1996;93:402–6.
  • Bakker AC, Joosten LA, Arntz OJ, Helsen MM, Bendele AM, et al. Prevention of murine collagen-induced arthritis in the knee and ipsilateral paw by local expression of human interleukin-1 receptor antagonist protein in the knee. Arthritis Rheum 1997;40:893–900.
  • Otani K, Nita I, Macaulay W, Georgescu HI, Robbins PD, Evans CH. Suppression of antigen-induced arthritis in rabbits by ex vivo gene therapy. J Immunol 1996;156:3558–62.
  • Pelletier JP, Caron JP, Evans C, Robbins PD, Georgescu HI, Jovanovic D, et al. In vivo suppression of early experimental osteoarthritis by interleukin-1 receptor antagonist using gene therapy. Arthritis Rheum 1997;40:1012–9.
  • Milner-Ladner U, Roberts CR, Franklin BN, Gay RE, Robbins PD, Evans CH, et al. Human IL-1Ra gene transfer into human synovial fibroblasts is chondroprotective. J Immunol 1997;158: 3492–8.
  • Evans CH, Robbins PD, Ghivizzani SC, Herndon JH, Kang R, Bahnson AB, et al. Clinical trial to assess the safety, feasibility, and efficacy of transferring a potentially anti-arthritic cytokine gene to human joints with rheumatoid arthritis. Hum Gene Ther 1996;7: 1261–80.
  • Apparailly F, Verwaerde C, Jacquet C, Auriault C, Sany J, Jorgensen C. Adenovirus-mediated transfer of viral IL-10 gene inhibits murine collagen-induced arthritis. J Immunol 1998;160: 5213–20.
  • Lechman ER, Jaffurs D, Ghivizzani SC, Gambotto A, Kovesdi I, Mi Z, et al. Direct adenoviral gene transfer of viral IL-10 to rabbit knees with experimental arthritis ameliorates disease in both injected and contralateral control knees. J Immunol 1999;163: 2202–8.
  • Ma Y, Thornton S, Duwel LE, Boivin GP, Giannini EH, Leiden JM, et al. Inhibition of collagen-induced arthritis in mice by viral IL-10 gene transfer. J Immunol 1998;161:1516–24.
  • Cush JJ, Splawski JB, Thomas R, McFarlin JE, Schulze KH, Davis LS, et al. Elevated interleukin-10 levels in patients with rheumatoid arthritis. Arthritis Rheum 1995;38:96–104.
  • Katsikis PD, Chu CQ, Brennan FM, Maini RN, Feldmann M. Immunoregulatory role of interleukin 10 in rheumatoid arthritis. J Exp Med 1994;179: 1517–27.
  • Song XY, Gu M, Jin WW, Klinman DM, Wahl SM. Plasmid DNA encoding transforming growth factor-p1 suppresses chronic disease in a streptococcal cell wall-induced arthritis model. J Chin Invest 1998;101: 2615–21.
  • Fava RA, Olsen NJ, Postlethwaite AE, Broadley KN, Davidson JM, Nanney LB, et al. Transforming growth factor (31 (TGF-p1)-induced neutrophil recruitment to synovial tissues: implications for TGF-beta-driven synovial inflammation and hyperplasia. J Exp Med 1991;173:1121–32.
  • Le CH, Nicolson AG, Morales A, Sewell KL. Suppression of collagen-induced arthritis through adenovirus-mediated transfer of a modified tumor necrosis factor a receptor gene. Arthritis Rheum 1997;40:1662–9.
  • Takayanagi H, Juji T, Miyazaki T, Iizuka H, Takahashi T, Isshiki M, et al. Suppression of arthritic bone destruction by adenovirus-mediated csk gene transfer to synoviocytes and osteoclasts. J Chin Invest 1999;104:137–46.
  • Okamoto K, Asahara H, Kobayashi T, Matsuno H, Hasunuma T, Kobata T, et al. Induction of apoptosis in the rheumatoid synovium by Fas ligand gene transfer. Gene Ther 1998;5:331–8.
  • Zhang H, Yang Y, Horton JL, Samoilova EB, Judge TA, Turka LA, et al. Amelioration of collagen-induced arthritis by CD95 (Apo-1/Fas)-ligand gene transfer. J Chin Invest 1997;100:1951–7.
  • Rabinovich GA, Daly G, Dreja H, Tailor H, Ftiera CM, Hirabayashi J, et al. Recombinant galectin-1 and its genetic delivery suppress collagen-induced arthritis via T cell apoptosis. J Exp Med 1999;190:385–98.
  • Persson S, Mikulowska A, Narula S, O'Garra A, Holmdahl R. Interleukin-10 suppresses the development of collagen type II-induced arthritis and ameliorates sustained arthritis in rats. Scand J Immunol 1996;44: 607–14.
  • Joosten LA, Lubberts E, Durez P, Helsen MM, Jacobs MJ, Goldman M, et al. Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis. Protective effect of interleukin-4 and interleukin-10 treatment on cartilage destruction. Arthritis Rheum 1997;40:249–60.
  • Firestein GS, Yeo M, Zvaifler NJ. Apoptosis in rheumatoid arthritis synovium. J Clin Invest 1995;96:1631–8.
  • Sherr CJ, Roberts JM. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev 1995;9:1149–63.
  • Taniguchi K, Kohsaka H, Inoue N, Terada Y, Ito H, Hirokawa K, et al. Induction of the pl6INK4a senescence gene as a new therapeutic strategy for the treatment of rheumatoid arthritis. Nat Med 1999;5:760–7.
  • Lois AF, Cooper LT, Geng Y, Nobori T, Carson DA. Expression of the p16 and p15 cyclin-dependent kinase inhibitors in lymphocyte activation and neuronal differentiation. Cancer Res 1995;55: 4010–3.
  • Alcorta DA, Xiong Y, Phelps D, Hannon G, Beach D, Barrett JC. Involvement of the cyclin-dependent kinase inhibitor pl6INK4a in replicative senescence of normal human fibroblasts. Proc Natl Acad Sci USA 1996;93:13742–7.
  • Kato D, Miyazawa K, Ruas M, Starborg M, Wada I, Oka T, et al. Features of replicative senescence induced by direct addition of antennapedia-pl6INK4A fusion protein to human diploid fibroblasts. FEBS Lett 1998;427:203–8.
  • Uhrbom L, Nistér M, Westermark B. Induction of senescence in human malignant glioma cells by p16INK4A. Oncogene 1997;15:505–14.
  • Fueyo J, Gomez MC, Yung WK, Clayman GL, Liu TJ, Bruner J, et al. Adenovirus-mediated p16/CDKN2 gene transfer induces growth arrest and modifies the transformed phenotype of glioma cells. Oncogene 1996;12:103–10.
  • Bondeson J, Foxwell B, Brennan F, Feldmann M. Defining therapeutic targets by using adenovirus: blocking NF-KB inhibits both inflammatory and destructive mechanisms in rheumatoid synovium but spares anti-inflammatory mediators. Proc Natl Acad Sci USA 1999;96:5668–73.
  • Foxwell B, Browne K, Bondeson J, Clarke C de MR, Brennan F, et al. Efficient adenoviral infection with IxBa reveals that macro-phage tumor necrosis factor a production in rheumatoid arthritis is NF-KB dependent. Proc Natl Acad Sci USA 1998;95:8211–5.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.