References
- Harris ED Jr, editor. Rheumatoid arthritis. Philadelphia: WB Saunders; 1997.
- Koch AE. Angiogenesis: implications for rheumatoid arthritis. Arthritis Rheum 1998;41:951–62.
- Albani S, Carson DA. Etiology and pathogenesis of rheu-matoid arthritis. In: Koopman WJ, editor. Arthritis and allied con-ditions. 13th ed. New York: Williams & Wilkins; 1997. p. 979–89.
- Bresnihan B. Pathogenesis of joint damage in rheumatoid arthritis. J Ftheumatol 1999;26:717–19.
- Monier S, Reme T, Cognot C, Gao QL. Growth factor activity of IL-6 in the synovial fluid of patients with rheumatoid arthritis. Clin Exp Ftheumatol 1994;12:595–602.
- Badolato R, Oppenheim JJ. Role of cytokines, acute phase pro-teins, and chemokines in the progression of rheumatoid arthritis. Semin Arthritis Rheum 1996;26:526–38.
- Peichl P, Pursch E, Broil H, Lindley U. Anti IL-8 autoantibodies and complexes in rheumatoid arthritis: polyclonal activation chronic synovial tissue inflammation. Ftheumatol Int 1999;18:141–5.
- Harada S, Yamamura M, Okamoto H, Morita Y, Kawashima M, Aita T, et al. Production of interleukin-7 and interleukin-15 by fibroblast-like synoviocytes from patients with rheumatoid arthri-tis. Arthritis Rheum 1999;42:1508–16.
- Suzuki Y, Nishikaku F, Nakatuka M, Koga Y. Osteoclast-like cells 23. in murine collagen induced arthritis. J Ftheumato11998;25:1154–60.
- Rudnicki JA, Brown AMC. Inhibition of chondrogenesis by Wnt gene expression in vivo and in vitro. Dev Biol 1997;185:104-18.24.
- Van Den Berg DJ, Sharma AK, Bruno E, Hoffman R. Role of members of the Wnt gene family in human hematopoiesis. Blood 1998;92:3189-202.25.
- Hartmann C, Tabin CJ. Dual roles of Wnt signaling during chon-drogenesis in the chicken limb. Development 2000;127:3141–59.
- Tomlinson A, Strapps WR, Heemskerk J. Linking Frizzled and 26. Wnt signaling in Drosophila development. Development 1997;124: 4515–21.
- Zhang J, Carthew RW. Interactions between wingless and Dfz2 27. during Drosophila wing development. Development 1998;125: 3075–85.
- Barnes MR, Duckworth DM, Beeley LJ. Frizzled proteins consti- 28. tute a novel family of G protein-coupled receptors most closely related to the secretin family. Trends Pharmacol Sci 1998;125: 3075–85.29.
- Fischer U, Meltzer P, Meese E. Twelve amplified and expressed genes localized in a single domain in glioma. Hum Genet 1996;98: 625–8.
- Calvo R, West J, Franklin W, Erickson P, Bemis L, Li E, et al. Altered Hox and Wnt7a expression in human lung cancer. Proc 30. Natl Acad Sci USA 2000;97:12776–81.
- Bui TD, Rankin J, Smith K, Huguet EL, Ruben S, Strachan T, et al. A novel human Wnt gene, Wntl0B, maps to 12q13 and is expressed in human breast carcinomas. Oncogene 1997;14:1249-31. 53.
- Lejeune S, Huguet EL, Hamby A, PonIsom R, Harris AL. Wnt5a cloning, expression, and up-regulation in human primary breast 32. cancers. Chin Cancer Res 1995;1: 215–22.
- Norihiko S, Gotaro T, Momoki H, Masaaki T, Masaru K. Molecu-lar cloning, differential expression and chromosomal localization 33. of human Frizzled-1, Frizzled-2 and Frizzled-7. Biochem Biophys Res Commun 1998;252: 117–22.
- Blankesteijn WM, Essers-Janssen YP, Ulrich MM, Smits JF. In- 34. creased expression of a homologue of drosophila tissue polarity gene "frizzled" in left ventricular hypertrophy in the rat, as identi- 35. fled by subtractive hybridization. J Mol Cell Cardiol 1996;28: 1187–91.
- Sen M, Lauterbach K, El-Gabalawy H, Firestein GS, Corr M, Carson DA. Expression and function of wingless and frizzled ho- 36. mologs in rheumatoid arthritis. Proc Natl Acad Sci USA 2000;97: 2791–6.
- Sen M, Chamorro M, Reifert J, Corr M, Carson DA. Blockade of Wnt5a/Frizzled5 signaling inhibits rheumatoid synoviocyte activa-tion. Arthritis Rheum 2001;44: 772–81.
- Miller JR, Hocking AM, Brown JD, Moon RT. Mechanism and function of signal transduction by the Wnt/beta-catenin and Wnt/ Ca2+ pathways. Oncogene 1999;18:7860–72.
- He TC, Sparks AB, Rago C, Hermeking H, Zawel L, da Costa LT, et al. Identification of c-MYC as a target of the APC pathway. Science 1998;281:1509–12.
- Bournat JC, Brown AM, Soler AP. Wntl dependent activation of the survival factor NF-kappaB in PC12 cells. J Neurosci Res 2000;61: 21–32.
- He X, Saint-Jeannet J-P, Wang Y, Nathans J, Dawid I, Varmus H. A member of the Frizzled protein family mediating axis induction by Wnt5a. Science 1997;275:1652–4.
- Slusarski DC, Corces VG, Moon RT. Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signaling. Nature 1997;390:410–3.
- Takayanagi H, Ezuka H, Juji T, Nakagawa T, Yamamoto A, Miyazaki T, et al. Involvement of receptor activator of nuclear factor kappaB ligand/osteoclast differentiation factor in osteo-clastogenesis from synoviocytes in rheumatoid arthritis. Arthritis Rheum 2000;43:259–69.
- Miyazawa K, Mori A, Yamamoto K, Okudaira H. Constitutive transcription of the human interleukin-6 gene by rheumatoid ar-thritis synoviocytes: spontaneous activation of NfkappaB and CBF1. Am J Pathol 1998;152:793–803.
- Ghosh S, May MJ, Kopp EB. NFkappaB and Rel proteins: evolu-tionarily conserved mediators of immune responses. Annu Rev Immunol 1998;16:225–60.
- Washizu J, Nishimura H, Nakamura N, Nimura Y, Yoshikai Y. The NFkappaB binding site is essential for transcriptional activation of the IL-15 gene. Immunogenetics 1998;48: 1–7.
- Varga J, Jimenez SA. Pathogenesis of scleroderma: Cellular as-pects. In: Clements PJ, Furst DE, editors. Systemic sclerosis, 1st ed. Baltimore: Williams & Wilkins; 1996. p. 123–52.
- Kapila YL, Lancer() H, Johnson PW. The response of periodontal ligament cells to fibronectin. J Periodontol 1998;69:1008–19.
- Di Matola T, Mueller F, Fenzi G, Rossi G, Bifulco M, Marzano LA, Vitale M. Serum withdrawal-induced apoptosis in thyroid cells is caused by loss of fibronectin-integrin interaction. J Clin Endocrinol Metab 2000;85:1188–93.
- Hartmann C, Tabin CJ. Wnt-14 plays a pivotal role in inducing synovial joint formation in the developing appendicular skeleton. Cell 2001;104:341–51.