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Clinical Intensive Care Volume 13, 2002 - Issue 2-3
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Research Article

Case report and review of the role of late Nacetylcysteine administration in fulminant hepatic failure secondary to acetaminophen toxicity in infancy

P. S. Puligandla Department of Pediatrics, Section of Pediatric Critical CareMedicine, Children‘s Hospital of Western Ontario, University of Western Ontario, London, Ontario, Canada.
,
G. Moore Department of Pediatrics, Section of Pediatric Critical CareMedicine, Children‘s Hospital of Western Ontario, University of Western Ontario, London, Ontario, Canada.
,
P. Atkison Department of Hepatology and Transplantation, Children‘s Hospitalof Western Ontario, University of Western Ontario, London, Ontario, Canada.
,
D. Matsui Department Pharmacology and Toxicology, Children‘s Hospitalof Western Ontario, University of Western Ontario, London, Ontario, Canada.
,
M. Rieder Department Pharmacology and Toxicology, Children‘s Hospitalof Western Ontario, University of Western Ontario, London, Ontario, Canada.
,
R. Lee Department Anaesthesia, Children‘s Hospital of Western Ontario, University of Western Ontario, London, Ontario, Canada.
&
Y. Ouellette Department of Pediatrics, Section of Pediatric Critical CareMedicine, Children‘s Hospital of Western Ontario, University of Western Ontario, London, Ontario, Canada.
 show all
Pages 127-130 | Published online: 04 Dec 2011

References

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  • Keays R, Harrison PM, Wendon, et al. Intravenous acetylcysteine in paracetamol-induced fulminant hepatic failure: a prospective controlled trial. BMJ 1991; 303:1026–1029.
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  • Lieh-Lai MW, Sarnaik AP, Newton JF, et al. Metabolism and pharmacokinetics of acetaminophen in a severely poi-soned young child. Pediatrics 1984; 105(1): 125–128.
  • Anker AL, Smilkstein MJ. Acetaminophen: concepts and controversies. Emerg. Med. Clin. North Am. 1994; 12(2): 335–349.
  • Shaheen N, Grim IS. Fulminant hepatic failure associated with clarithromycin. Am. J. Gastroenterol. 1996; 91(2): 394–395.
  • Hall DE, Eubanks L, Meyyazhagan S. et al. Evaluation of covert video surveillance in the diagnosis of Munchausen Syndrome by Proxy: lessons from 41 cases. Pediatrics 2000; 105(6): 1305–1312.

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