REFERENCES

• MadrazoI.LeonV.TorresC.et al.Transplantation of fetal substantia nigra and adrenal medulla to the caudade putamen in two patients with Parkinson's disease.N Engl J Med.1988318513336384
   PubMed Web of Science ®Google Scholar
• BacklundE.GranbergP.HambergerB.et al.Transplantation of adrenal medullary tissue to striatum in parkinsonism.J Neurosurg.1985621691732578558
   PubMed Web of Science ®Google Scholar
• FreedWJ.MolikisaJM.SpoolE.et al.Transplanted adrenal chromaffin cells in rat brain reduce lesion-induced rotational behaviour.Nature.19812923513527254334
   PubMed Web of Science ®Google Scholar
• BjorklundA.SteneviU.Reconstruction of the nigrostriatal dopamine pathway by intracerebral nigral transplants.Brain Res.1979177555560574053
   PubMed Web of Science ®Google Scholar
• PerlowMJ.FreedWJ.HofferBJ.et al.Brain grafts reduce motor abnormalities produced by destruction of nigrostriatal dopamine system.Science.1979204643647571147
   PubMed Web of Science ®Google Scholar
• BrundinP.DuanW.SauerH.Functional effects of mesencephalic dopamine neurons and adrenal chromaffin cells grafted to the rodent striatum. In: Dunnett S, Bjorklund A, eds.Functional Neural Transplantation. Vol 2. New York, NY: Raven Press;1994946
   Google Scholar
• AnnettLE.MartelFL.RogersDC.et al.Behavioral assessment of the effects of embryonic nigral grafts in marmosets with unilateral 6-OHDA lesions of the nigrostriatal pathway.Exp Neurol.19941252282467906227
   PubMed Web of Science ®Google Scholar
• BjorklundA.DunnettSB.SteneviV.LewisME.IversenSD.Reinnervation of the denervated striatum by substantia nigra transplants: functional consequences as revealed by pharmacological and sensorimotor testing.Brain Res.19801993073337417786
   PubMed Web of Science ®Google Scholar
• CarderRK.Snyder-KellerAM.LundRD.Behavioral and anatomical correlates of immunologically induced rejection of nigral xenografts.J Comp Neurol.19882773914022904453
   PubMed Web of Science ®Google Scholar
• DunnettSB.HernandezTD.SummerfieldA.JonesGH.ArbuthnottG.Graft-derived recovery from 6-OHDA lesions: specificity of ventral mesencephalic graft tissue.Exp Brain Res.1988714114242901978
   PubMed Web of Science ®Google Scholar
• BrownellAL.LivniE.GalpernW.IsacsonO.In vivo PET imaging in rat of dopamine terminals reveals functional neural transplants.Ann Neurol.1998433873909506557
   PubMed Web of Science ®Google Scholar
• FreedCR.BreezeRE.RosenbergNL.et al.Transplantation of human fetal dopamine cells for Parkinson's disease. Results at 1 year.Arch Neurol.1990475055122334298
   PubMedGoogle Scholar
• LindvallO.RehncronaS.GustaviiB.et al.Fetal dopamine-rich mesencephalic grafts in Parkinson's disease.Lancet.19882148314842904587
   PubMed Web of Science ®Google Scholar
• BjorklundA.DunnettSB.BrundinP.et al.Neural transplantation for the treatment of Parkinson's disease.Lancet Neurol.2003243744512849125
   PubMed Web of Science ®Google Scholar
• HagellP.PicciniP.BjorklundA.et al.Dyskinesias following neural transplantation in Parkinson's disease.Nat Neurosci.2002562762812042822
   PubMed Web of Science ®Google Scholar
• PicciniP.LindvallO.BjorklundA.et al.Delayed recovery of movementrelated cortical function in Parkinson's disease after striatal dopaminergic grafts.Ann Neurol.20004868969511079531
   PubMed Web of Science ®Google Scholar
• BrundinP.PogarellO.HagellP.et al.Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease.Brain.2000123(Pt 7)1380139010869050
   PubMed Web of Science ®Google Scholar
• PicciniP.BrooksDJ.BjorklundA.et al.Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient.Nat Neurosci.199921137114010570493
   PubMed Web of Science ®Google Scholar
• HagellP.SchragA.PicciniP.et al.Sequential bilateral transplantation in Parkinson's disease: effects of the second graft.Brain.1999122(Pt 6)1121113210356064
   PubMed Web of Science ®Google Scholar
• WenningGK.OdinP.MorrishP.et al.Short- and long-term survival and function of unilateral intrastriatal dopaminergic grafts in Parkinson's disease.Ann Neurol.199742951079225690
   PubMed Web of Science ®Google Scholar
• WidnerH.TertrudJ.RehncronaS.et al.Fifteen months' follow-up on bilateral embryonic mesencephalic grafts in two cases of severe MPTP-induced parkinsonism.Adv Neurol.1993607297338420218
   PubMedGoogle Scholar
• WidnerH.TertrudJ.RehncronaS.et al.Bilateral fetal mesencephalic grafting in two patients with severe parkinsonism induced by MPTP.N Engl J Med.1992327155615631435882
   PubMed Web of Science ®Google Scholar
• SawleGV.BloomfieldPM.BjorklundA.Transplantation of fetal dopamine neurons in Parkinson's disease: positron emission tomography [18F]-6-L-fluorodopa studies in two patients with putamina implants.Ann Neurol.1992311661731575455
   PubMedGoogle Scholar
• LindvallO.WidnerH.RehncronaS.et al.Transplantation of fetal dopamine neurons in Parkinson's disease: 1-year clinical and neurophysiological observations in two patients with putaminal implants.Ann Neurol.1992311551651575454
   PubMed Web of Science ®Google Scholar
• LindvallO.BrundinP.WidnerH.et al.Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease.Science.19902475745772105529
   PubMed Web of Science ®Google Scholar
• LindvallO.RehncronaS.BrundinP.et al.Neural transplantation in Parkinson's disease: the Swedish experience.Prog Brain Res.1990827297342290977
   PubMed Web of Science ®Google Scholar
• LindvallO.BrundinP.RehncronaS.et al.Human fetal dopamine neurons grafted into the striatum in two patients with severe Parkinson's disease: a detailed account of methodology and a 6-month follow-up.Arch Neurol.1989466156312786405
   PubMed Web of Science ®Google Scholar
• BreezeRE.WellsTH Jr.FreedCR.Implantation of fetal tissue for the management of Parkinson's disease: a technical note.Neurosurgery.199536104410477791972
   PubMed Web of Science ®Google Scholar
• FreedCR.BreezeRE.RosenbergNL.et al.Survival of implanted fetal dopamine cells and neurologic improvement 12 to 46 months after transplantation for Parkinson's disease.N Engl J Med.1992327154915551435881
   PubMed Web of Science ®Google Scholar
• FreedCR.RosenbergNL.SchneckSA.BreezeRE.Improved drug responsiveness following fetal tissue implant for Parkinson's disease.Neurochem Int.199220 (suppl)321S327S1365449
   PubMed Web of Science ®Google Scholar
• FreedCR.GreenePE.BreezeRE.et al.Transplantation of embryonic dopamine neurons for severe Parkinson's disease.N Engl J Med.200134471071911236774
   PubMed Web of Science ®Google Scholar
• OlanowCW.GoetzCG.KoldowerJH.et al.A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease.Ann Neurol.20035440341412953276
   PubMed Web of Science ®Google Scholar
• FreedCR.Will embryonic stem cells be a useful source of dopamine neurons for transplant into patients with Parkinson's disease?Proc Natl Acad Sci U S A.2002991755175711854478
   PubMed Web of Science ®Google Scholar
• ArenasE.Stem cells in the treatment of Parkinson's disease.Brain Res Bull.20025779580812031276
   PubMed Web of Science ®Google Scholar
• IsacsonO.The production and use of cells as therapeutic agents in neurodegenerative diseases.Lancet Neurol.2003241742412849120
   PubMed Web of Science ®Google Scholar
• EvansMJ.KaufmanMH.Establishment in culture of pluripotential cells from mouse embryos.Nature.19812921541567242681
   PubMed Web of Science ®Google Scholar
• MartinGR.Isolation of a pleuripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells.Proc Natl Acad Sci U S A.198178763476386950406
   PubMed Web of Science ®Google Scholar
• PedersonRA.Embryonic stem cells for medicine.Sci Am.1999April6873
   Google Scholar
• ShermanMl.MillerRA.RichterCB.Histologie analyses of experimental tumors from mouse blastocyst-derived cell lines.J Natl Cancer Inst.1977589931002846000
   PubMedGoogle Scholar
• BainG.KitchensD.YaoM.HuettnerJE.GottliebDl.Embryonic stem cells express neuronal properties in vitro.Dev Biol.19951683423577729574
   PubMed Web of Science ®Google Scholar
• BarberiT.KlivenyiP.CalingasanNY.et al.Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice.Nat Biotechnol.2003211200120714502203
   PubMed Web of Science ®Google Scholar
• TropepeV.HitoshiS.SirardC.et al.Direct neural fate specification from embryonic stem cells. A primitive mammalian neural stem cell stage acquired through a default mechanism.Neuron.200130657811343645
   PubMed Web of Science ®Google Scholar
• Munoz-SanjuanI.BrivanlouAH.Neural induction, the default model and embryonic stem cells.Nat Rev Neurosci.2002327128011967557
   PubMed Web of Science ®Google Scholar
• DeaconT.DinsmouJ.CostantiniLC.RatliffJ.IsacsonO.Blastula-derived stem cells can differentiate into dopaminergic and serotonergic neurons after transplantation.Exp Neurol.199814928419454612
   PubMed Web of Science ®Google Scholar
• BjorklundLM.Sanchez-PernauteR.ChungS.et al.Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model.Proc Natl Acad Sci U S A.2002992344234911782534
   PubMed Web of Science ®Google Scholar
• LeeSH.LumelskyN.StuderL.AverbackJM.McKayRD.Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells.Nat Biotechnol.20001867567910835609
   PubMed Web of Science ®Google Scholar
• ChungS.SonntagKC.AnderssonT.et al.Genetic engineering of mouse embryonic stem cells by Nurr 1 enhances differentiation and maturation into dopaminergic neurons.Eur J Neurosci.2002161829183812453046
   PubMed Web of Science ®Google Scholar
• KimJH.AverbackJM.Rodriguez-GomezJA.et al.Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease.Nature.2002418505612077607
   PubMed Web of Science ®Google Scholar
• NishimuraF.YoshikawaM.KandaS.et al.Potential use of embryonic stem cells for the treatment of mouse parkinsonian models: improved behavior by transplantation of in vitro differentiated dopaminergic neurons from embryonic stem cells.Stem Cells.20032117118012634413
   PubMed Web of Science ®Google Scholar
• KawasakiH.MizusekiK.NishikawaS.et al.Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity.Neuron.200028314011086981
   PubMed Web of Science ®Google Scholar
• WakayamaT.TabarV.RodriguezI.et al.Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer.Science.200129274074311326103
   PubMed Web of Science ®Google Scholar
• YingQL.StavridisM.GriffithsD.LiM.SmithA.Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture.Nat Biotechnol.20032118318612524553
   PubMed Web of Science ®Google Scholar
• ThomsonJA.KalishmanJ.GolosTG.et al.Isolation of a primate embryonic stem cell line.Proc Natl Acad Sci USA.199592784478487544005
   PubMed Web of Science ®Google Scholar
• ThomsonJA.KalishmanJ.GolosTG.et al.Pluripotent cell lines derived from common marmoset (Callithrix jacchus) blastocysts.Biol Reprod.1996552542598828827
   PubMed Web of Science ®Google Scholar
• ThomsonJA.Itskovitz-EldorJ.ShapiroSS.et al.Embryonic stem cells derived from human blastocysts.Science.1998282114511479804556
   PubMed Web of Science ®Google Scholar
• KawasakiH.SuemoriH.MizusekiK.et al.Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cellderived inducing activity.Proc Natl Acad Sci USA.2002991580158511818560
   PubMed Web of Science ®Google Scholar
• VranaKE.HippJD.GossAM.et al.Nonhuman primate parthenogenetic stem cells.Proc Natl Acad Sci US A.2003100(suppl 1)1191111916
   PubMed Web of Science ®Google Scholar
• ZhangSC.WernigM.DuncanID.BrustleO.ThomsonJA.In vitro differentiation of transplantable neural precursors from human embryonic stem cells.Nat Biotechnol.2001191129113311731781
   PubMed Web of Science ®Google Scholar
• CarpenterMK.InokumaMS.DenhamJ.et al.Enrichment of neurons and neural precursors from human embryonic stem cells.Exp Neurol.200117238339711716562
   PubMed Web of Science ®Google Scholar
• ReubinoffBE.ItsyksonP.TuretskyT.et al.Neural progenitors from human embryonic stem cells.Nat Biotechnol.2001191134114011731782
   PubMed Web of Science ®Google Scholar
• MatsuiY.ZseboK.HoganBL.Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture.Cell.1992708418471381289
   PubMed Web of Science ®Google Scholar
• ShamblottMJ.AxelmanJ.WangS.et al.Derivation of pluripotent stem cells from cultured human primordial germ cells.Proc Natl Acad Sci U S A.19989513726137319811868
   PubMed Web of Science ®Google Scholar
• KerrDA.LladoJ.ShamblottMJ.et al.Human embryonic germ cell derivatives facilitate motor recovery of rats with diffuse motor neuron injury.J Neurosci.2003235131514012832537
   PubMed Web of Science ®Google Scholar
• JoheKK.HazelTG.MullerT.Dugish-DiordjevicMM.McKayRD.Single factors direct the differentiation of stem cells from the fetal and adult central nervous system. Functions of basic fibroblast growth factor and neurotrophins in the differentiation of hippocampal neurons.Genes Dev.199610312931408985182
   PubMed Web of Science ®Google Scholar
• ReynoldsBA.WeissS.Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system.Science.1992255170717101553558
   PubMed Web of Science ®Google Scholar
• DaadiMM.WeissS.Generation of tyrosine hydroxylase-producing neurons from precursors of the embryonic and adult forebrain.J Neurosci.1999194484449710341249
   PubMed Web of Science ®Google Scholar
• CarpenterMK.CuiX.HuZY.et al.In vitro expansion of a multipotent population of human neural progenitor cells.Exp Neurol.199915826527810415135
   PubMed Web of Science ®Google Scholar
• SvendsenCN.CaldwellMA.ShenJ.et al.Long-term survival of human central nervous system progenitor cells transplanted into a rat model of Parkinson's disease.Exp Neurol.19971481351469398456
   PubMed Web of Science ®Google Scholar
• YangM.StullND.BerkMA.SnyderEY.lacovittiL.Neural stem cells spontaneously express dopaminergic traits after transplantation into the intact or 6-hydroxydopamine-lesioned rat.Exp Neurol.2002177506012429210
   PubMed Web of Science ®Google Scholar
• OurednikJ.OurednikV.LynchWP.SchachnerM.SnyderEY.Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons.Nat Biotechnol.20022011031012379867
   PubMed Web of Science ®Google Scholar
• ZetterstromRH.SolomlnL.JanssonL.et al.Dopamine neuron agenesis in Nurrl-deficient mice.Science.19972762482509092472
   PubMed Web of Science ®Google Scholar
• WagnerJ.AkerudP.CastroDS.et al.Induction of a midbrain dopaminergic phenotype in Nurr1-overexpressing neural stem cells by type 1 astrocytes.Nat Biotechnol.19991765365910404157
   PubMed Web of Science ®Google Scholar
• LeeVMY.AndrewsPW.Differentiation of NTERA-2 clonal human embryonal carcinoma cells into neurons involves the induction of all three neurofilament proteins.J Neurosci.198665145212419526
   PubMed Web of Science ®Google Scholar
• IacovittiL.StullND.Expression of tyrosine hydroxylase in newly differentiated neurons from a human cell line (hNT).Neuroreport.19978147114749172156
   PubMed Web of Science ®Google Scholar
• ZigovaT.BarrosoLF.WillingAE.et al.Dopaminergic phenotype of hNT cells in vitro.Brain Res Dev Brain Res.20001228790
   PubMedGoogle Scholar
• SaportaS.WillingAE.ColinaLO.et al.In vitro and in vivo characterization of hNT neuron neurotransmitter phenotypes.Brain Res Bull.20005326326811113579
   PubMed Web of Science ®Google Scholar
• BakerKA.HongM.SadiD.MendezI.Intrastriatal and intranigral grafting of hNT neurons in the 6-OHDA rat model of Parkinson's disease.Exp Neurol.200016235036010739641
   PubMed Web of Science ®Google Scholar
• MeyerM.JohansenJ.GramsbergenJB.JohansenTE.ZirnmerJ.Improved survival of embryonic porcine dopaminergic neurons in coculture with a conditionally immortalized GDNF-producing hippocampal cell line.Exp Neurol.2000164829310877918
   PubMed Web of Science ®Google Scholar
• OstenfeldT.TaiYT.MartinP.et al.Neurospheres modified to produce glial cell line-derived neurotrophic factor increase the survival of transplanted dopamine neurons.J Neurosci Res.20026995596512205689
   PubMed Web of Science ®Google Scholar
• AkerudP.CAnalsJM.SnyderEY.ArenasE.Neuroprotection through delivery of glial cell line-derived neurotrophic factor by neural stem cells in a mouse model of Parkinson's disease.J Neurosci.2001218108811811588183
   PubMed Web of Science ®Google Scholar
• AkerudP.HOmPC.Castelo-BrancoG.et al.Persephin-overexpressing neural stem cells regulate the function of nigral dopaminergic neurons and prevent their degeneration in a model of Parkinson's disease.Mol Cell Neurosci.20022120522212401443
   PubMed Web of Science ®Google Scholar
• GillSS.PatelNK.HottonGR.et al.Direct brain infusion of glial cell linederived neurotrophic factor in Parkinson disease.Nat Med.2003958959512669033
   PubMed Web of Science ®Google Scholar
• StuderL.TabarV.McKayRD.Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats.Nat Neurosci.1998129029510195162
   PubMed Web of Science ®Google Scholar
• StuderL.CseteM.LeeSH.et al.Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen.J Neurosci.2000207377738311007896
   PubMed Web of Science ®Google Scholar
• YanJ.StuderL.McKayRD.Ascorbic acid increases the yield of dopaminergic neurons derived from basic fibroblast growth factor expanded mesencephalic precursors.J Neurochem.20017630731111146004
   PubMed Web of Science ®Google Scholar
• Sanchez-PernauteR.StuderL.BankiewiczKS.MajorEO.McKayRD.In vitro generation and transplantation of precursor-derived human dopamine neurons.J Neurosci Res.20016528428811494363
   PubMed Web of Science ®Google Scholar
• BrundinP.BjorklundA.Survival of expanded dopaminergic precursors is critical for clinical trials.Nat Neurosci.1998153710196555
   PubMed Web of Science ®Google Scholar
• LingZD.PotterED.LiptonJW.CarveyPM.Differentiation of mesencephalic progenitor cells into dopaminergic neurons by cytokines.Exp Neurol.19981494114239500954
   PubMed Web of Science ®Google Scholar
• PotterED.LingZD.CarveyPM.Cytokine-induced conversion of mesencephalic-derived progenitor cells into dopamine neurons.Cell Tiss Res.1999296235246
   PubMed Web of Science ®Google Scholar
• CarveyPM.LingZD.SortwellCE.et al.A clonal line of mesencephalic progenitor cells converted to dopamine neurons by hematopoietic cytokines: a source of cells for transplantation in Parkinson's disease.Exp Neurol.20011719810811520124
   PubMed Web of Science ®Google Scholar
• StorchA.PaulG.CseteM.et al.Long-term proliferation and dopaminergic differentiation of human mesencephalic neural precursor cells.Exp Neurol.200117031732511476598
   PubMed Web of Science ®Google Scholar
• RiazSS.JauniauxE.SternGM.BradfordHF.The controlled conversion of human neural progenitor cells derived from foetal ventral mesencephalon into dopaminergic neurons in vitro.Brain Res Dev Brain Res.20021362734
   PubMedGoogle Scholar
• AltmanJ.Are new neurons formed in the brains of adult mammals?Science.19621351127112813860748
   PubMed Web of Science ®Google Scholar
• RichardsLJ.KilpatrickTJ.BartlettPF.De novo generation of neuronal cells from the adult mouse brain.Proc Natl Acad Sci U S A.199289859185951528866
   PubMed Web of Science ®Google Scholar
• GageFH.CoatesPW.PAImerTD.Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brainProc Natl Acad Sci USA.19959211879118838524867
   PubMed Web of Science ®Google Scholar
• PalmerTD.TakahashiJ.GageFH.The adult rat hippocampus contains primordial neural stem cells.Mol Cell Neurosci.199783894049143557
   PubMed Web of Science ®Google Scholar
• KempermannG.WiskottL.GageFH.Functional significance of adult neurogenesis.Curr Opin Neurobiol.2004141869115082323
   PubMed Web of Science ®Google Scholar
• FallonJ.reidS.KinyamuR.et al.In vivo induction of massive proliferation, directed migration, and differentiation of neural cells in the adult mammalian brain.Proc Natl Acad Sci U S A.200097146861469111121069
   PubMed Web of Science ®Google Scholar
• ZhaoM.MommaS.DelfaniK.et al.Evidence for neurogenesis in the adult mammalian substantia nigra.Proc Natl Acad Sci U S A.20031007925793012792021
   PubMed Web of Science ®Google Scholar
• LieDC.DziewczapolskiG.WillhoiteAR.et al.The adult substantia nigra contains progenitor cells with neurogenic potential.J Neurosci.2002226639664912151543
   PubMed Web of Science ®Google Scholar
• IacopinoAM.ChristakosS.Specific reduction of calcium-binding protein (28-kilodalton calbindin-D) gene expression in aging and neurodegenerative diseases.Proc Natl Acad Sci U S A.199087407840822140897
   PubMed Web of Science ®Google Scholar
• YamadaT.McGeerPL.BaimbridgeKG.McGeerEG.Relative sparing in Parkinson's disease of substantia nigra dopamine neurons containing calbindin-D28K.Brain Res.19905263033072257487
   PubMed Web of Science ®Google Scholar
• ItoH.GotoS.SakamotoS.HiranoA.Calbindin-D28k in the basal ganglia of patients with parkinsonism.Ann Neurol.1992325435501456738
   PubMed Web of Science ®Google Scholar
• GibbWR.Melanin, tyrosine hydroxylase, calbindin and substance P in the human midbrain and substantia nigra in relation to nigrostriatal projections and differential neuronal susceptibility in Parkinson's disease.Brain Res.19925812832911382801
   PubMed Web of Science ®Google Scholar
• DahlstromA.FuxeK.Localization of monoamines in the lower brain stem.Experientia.1964203983995856530
   PubMedGoogle Scholar
• GerfenCR.HerkenhamM.ThibaultJ.The neostriatal mosaic: II. Patchand matrix-directed mesostriatal dopaminergic and non-dopaminergic systems.J Neurosci.19877391539342891799
   PubMed Web of Science ®Google Scholar
• DamierP.HirschEC.AgidY.GraybielAM.The substantia nigra of the human brain. I. Nigrosomes and the nigral matrix, a compartmental organization based on calbindin D(28K) immunohistochemistry [see comments].Brain.1999122 (Pt 8)1421143610430829
   PubMed Web of Science ®Google Scholar
• CostantiniLC.LinL.IsacsonO.Medial fetal ventral mesencephalon: a preferred source for dopamine neuron grafts.Neuroreport.19978225322579243621
   PubMed Web of Science ®Google Scholar
• HaqueN.LeBlancC.IsacsonO.Differential dissection of the rat E16 ventral mesencephalon and survival and reinnervation of the 6-OHDAlesioned striatum by a subset of aldehyde dehydrogenase-positive TH neurons.Cell Transplant.199762392489171157
   PubMed Web of Science ®Google Scholar
• BjorklundL.HerlihyD.IsacsonO.Cell and synaptic replacement therapy for Parkinson's disease: current status and future directions.Neurosci News.20003612
   Google Scholar
• BjorklundLM.IsacsonO.Regulation of dopamine cell type and transmitter function in fetal and stem cell transplantation for Parkinson's disease.Prog Brain Res.200213841142012432781
   PubMed Web of Science ®Google Scholar
• IsacsonO.BjorklundLM.SchumacherJM.Toward full restoration of synaptic and terminal function of the dopaminergic system in Parkinson's disease by stem cells.Ann Neurol.200353(3 suppl 1)S135S14812666105
   PubMed Web of Science ®Google Scholar
• RamachandranAC.BartlettLE.MendezIM.A multiple target neural transplantation strategy for Parkinson's disease.Rev Neurosci.20021324325612405227
   PubMed Web of Science ®Google Scholar