789
Views
36
CrossRef citations to date
0
Altmetric
Translational Research

Neuroplasticity of excitatory and inhibitory cortical circuits in schizophrenia

Neuroplasticidad de los circuitos corticales excitatorios e inhibitorios en la esquizofrenia

Neuroplasticité des circuits corticaux excitateurs et inhibiteurs dans la schizophrénie

Pages 269-280 | Published online: 01 Apr 2022

REFERENCES

  • LewisDA.Gonzalez-BurgosG.Neuroplasticity of neocortical circuits in schizophrenia.Neuropsychopharmacology Reviews.20083314116517805309
  • LewisDA.SweetRA.Schizophrenia from a neural circuitry perspective: advancing toward rational pharmacological therapies.J Clin Invest.200911970671619339762
  • GoldJM.Cognitive deficits as treatment targets in schizophrenia.Schizophr Res.200472212815531404
  • GreenMF.What are the functional consequences of neurocognitive deficits in schizophrenia?.Am J Psychiatry.19961533213308610818
  • MacDonaldAW.IIICarterCS.et al.Specificity of prefrontal dysfunction and context processing deficits to schizophrenia in never-medicated patients with first-episode psychosis.Am J Psychiatry.200516247548415741464
  • BarchDM.ShelineYl.CsernanskyJG.SnyderAZ.Working memory and prefrontal cortex dysfunction: specificity to schizophrenia compared with major depression.Biol Psychiatry.20035337638412614990
  • HashimotoT.BazmiHH.MimicsK.WuQ.SampsonAR.LewisDA.Conserved regional patterns of GABA-related transcript expression in the neocortex of subjects with schizophrenia.Am J Psychiatry.200816547948918281411
  • OlneyJW.FarberNB.Glutamate receptor dysfunction and schizophrenia.Arch Gen Psychiatry.19955299810077492260
  • MoghaddamB.Bringing order to the glutamate chaos in schizophrenia.Neuron.20034088188414659087
  • KrystalJH.KarperLP.SeibylJP.et al.Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.Arch Gen Psychiatry.1994511992148122957
  • VermaA.MoghaddamB.NMDA receptor antagonists impair prefrontal cortex function as assessed via spatial delayed alternation performance in rats: modulation by dopamine.J Neurosci.1996163733798613804
  • DudkinKN.KruchininVK.ChuevaIV.Neurophysiological correlates of delayed visual differentiation tasks in monkeys: the effects of the site of intracortical blockade of NMDA receptors.Neurosci Behav Physiol.20013120721811388375
  • KonradiC.HeckersS.Molecular aspects of glutamate dysregulation: implications for schizophrenia and its treatment.Pharmacol Ther.20039715317912559388
  • KristiansenLV.HuertaI.BeneytoM.Meador-WoodruffJH.NMDA receptors and schizophrenia.Cuir Opin Pharmacol.200774855
  • ThuneJJ.UylingsHBM.PakkenbergB.No deficit in total number of neurons in the prefrontal cortex in schizophrenics.J Psychiatr Res.200135152111287052
  • AkbarianS.KimJJ.PotkinSG.et al.Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics.Arch Gen Psychiatry.1995522582667702443
  • SelemonLD.RajkowskaG.Goldman-RakicPS.Abnormally high neuronal density in the schizophrenic cortex: A morphometric analysis of prefrontal area 9 and occipital area 17.Arch Gen Psychiatry.1995528058187575100
  • SelemonLD.Goldman-RakicPS.The reduced neuropil hypothesis: A circuit based model of schizophrenia.Biol Psychiatry.19994517259894571
  • GlantzLA.LewisDA.Reduction of synaptophysin immunoreactivity in the prefrontal cortex of subjects with schizophrenia: regional and diagnostic specificity.Arch Gen Psychiatry.1997549439529337775
  • KarsonCN.MrakRE.SchlutermanKO.StumerWQ.ShengJG.GriffinWST.Alterations in synaptic proteins and their encoding mRNAs in prefrontal cortex in schizophenia: a possible neurochemical basis for “hypofrontality”.Mol Psychiatry.19994394510089007
  • Perrone-BizzozeroNI.SowerAC.BirdED.BenowitzLI.IvinsKJ.NeveRL.Levels of the growth-associated protein GAP-43 are selectively increased in association cortices in schizophrenia.Proc Natl Acad Sci USA.19969314182141878943081
  • MimicsK.MiddletonFA.MarquezA.LewisDA.LevittP.Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex.Neuron.200028536711086983
  • ZuoY.LinA.ChangP.GanWB.Development of long-term dendritic spine stability in diverse regions of cerebral cortex.Neuron.20054618118915848798
  • GareyLJ.OngWY.PatelTS.et al.Reduced dendritic spine density on cerebral cortical pyramidal neurons in schizophrenia.J Neurol Neurosurg Psychiatry.1998654464539771764
  • GlantzLA.LewisDA.Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia.Arch Gen Psychiatry.200057657310632234
  • JonesEG.Laminar distribution of cortical efferent cells. In: Peters A, Jones EG, eds.Cerebral Cortex.Vol 1. New York, NY: Plenum Press; 1984521553
  • KolluriN.SunZ.SampsonAR.LewisDA.Lamina-specific reductions in dendritic spine density in the prefrontal cortex of subjects with schizophrenia.Am J Psychiatry.20051621200120215930070
  • HayesTL.LewisDA.Magnopyramidal neurons in the anterior motor speech region: Dendritic features and interhemispheric comparisons.Arch Neurol.199653127712838970455
  • LundJS.LundRD.HendricksonAE.BuntAH.FuchsAF.The origin of efferent pathways from the primary visual cortex, area 17, of the macaque monkey as shown by retrograde transport of horseradish peroxidase.J Comp Neurol.1975164287304810501
  • PierriJN.VolkCLE.AuhS.SampsonA.LewisDA.Decreased somal size of deep layer 3 pyramidal neurons in the prefrontal cortex of subjects with schizophrenia.Arch Gen Psychiatry.20015846647311343526
  • RajkowskaG.SelemonLD.Goldman-RakicPS.Neuronal and glial somal size in the prefrontal cortex: A postmortem morphometric study of schizophrenia and Huntington disease.Arch Gen Psychiatry.1998552152249510215
  • SweetRA.PierriJN.AuhS.SampsonAR.LewisDA.Reduced pyramidal cell somal volume in auditory association cortex of subjects with schizophrenia.Neuropsychopharm.200328599609
  • SweetRA.BergenSE.SunZ.SampsonAR.PierriJN.LewisDA.Pyramidal cell size reduction in schizophrenia: Evidence for involvement of auditory feedforward circuits.Biol Psychiatry.2004551128113715184031
  • AndersonSA.ClasseyJD.CondéF.LundJS.LewisDA.Synchronous development of pyramidal neuron dendritic spines and parvalbumin-immunoreactive chandelier neuron axon terminals in layer III of monkey prefrontal cortex.Neuroscience.1995677227477911
  • ArellanoJl.EspinosaA.FairenA.YusteR.DeFelipeJ.Non-synaptic dendritic spines in neocortex.Neuroscience.200714546446917240073
  • BourgeoisJ-P.Goldman-RakicPS.RakicP.Synaptogenesis in the prefrontal cortex of rhesus monkeys.Cereb Cortex.1994478968180493
  • HuttenlocherPR.DabholkarAS.Regional differences in synaptogenesis in human cerebral cortex.J Comp Neurol.19973871671789336221
  • GieddJN.BlumenthalJ.JeffriesNO.et al.Brain development during childhood and adolescence: a longitudinal MRI study.Nat Neurosci.1999286186310491603
  • GogtayN.GieddJN.LuskL.et al.Dynamic mapping of human cortical development during childhood through early adulthood.Proc Natl Acad Sci USA.20041018174817915148381
  • MirnicsK.MiddletonFA.LewisDA.LevittP.Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse.Trends Neurosci.20012447948611476888
  • FeinbergI.Schizophrenia: Caused by a fault in programmed synaptic elimination during adolescence?.J Psychiatry Res.198217319334
  • KeshavanMS.AndersonS.PettegrewJW.Is schizophrenia due to excessive synaptic pruning in the prefrontal cortex? The Feinberg hypothesis revisited.J Psychiatry Res.199428239265
  • KatzLC.ShatzCJ.Synaptic activity and the construction of cortical circuits.Science.1996274113311388895456
  • Le BeJV.MarkramH.Spontaneous and evoked synaptic rewiring in the neonatal neocortex. ProcNatl Acad Sci USA.20061031321413219
  • Gonzalez-BurgosG.KroenerS.ZaitsevAV.et al.Functional maturation of excitatory synapses in layer 3 pyramidal neurons during postnatal development of the primate prefrontal cortex.Cereb Cortex.20081862663717591597
  • WooT-U.PucakML.KyeCH.MatusCV.LewisDA.Peripubertal refinement of the intrinsic and associational circuitry in monkey prefrontal cortex.Neuroscience.199780114911589284067
  • VolkDW.AustinMC.PierriJN.SampsonAR.LewisDA.Decreased glutamic acid decarboxylase67 messenger RNA expression in a subset of prefrontal cortical gamma-aminobutyric acid neurons in subjects with schizophrenia.Arch Gen Psychiatry.20005723724510711910
  • GuidottiA.AutaJ.DavisJM.et al.Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder.Arch Gen Psychiatry.2000571061106911074872
  • VawterMP.CrookJM.HydeTM.et al.Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: a preliminary study.Schizophr Res.200258112012363385
  • HashimotoT.BergenSE.NguyenQL.et al.Relationship of brainderived neurotrophic factor and its receptor TrkB to altered inhibitory prefrontal circuitry in schizophrenia.J Neurosci.20052537238315647480
  • HashimotoT.ArionD.UngerT.et al.Alterations in GABA-related transcriptome in the dorsolateral prefrontal cortex of subjects with schizophrenia.Mol Psychiatry.20081314716117471287
  • StraubRE.LipskaBK.EganMF.et al.Allelic variation in GAD1 (GAD67) is associated with schizophrenia and influences cortical function and gene expression.Mol Psychiatry.20071285486917767149
  • VolkDW.AustinMC.PierriJN.SampsonAR.LewisDA.GABA transporter-1 mRNA in the prefrontal cortex in schizophrenia: decreased expression in a subset of neurons.Am J Psychiatry.200115825626511156808
  • WilliamsSM.Goldman-RakicPS.LeranthC.The synaptology of parvalbumin-immunoreactive neurons in primate prefrontal cortex.J Comp Neurol.19923203533691613130
  • MelchitzkyDS.SesackSR.LewisDA.Parvalbumin-immunoreactive axon terminals in macaque monkey and human prefrontal cortex: Laminar, regional and target specificity of Type I and Type II synapses.J Comp Neurol.1999408112210331577
  • WooT-U.MillerJL.LewisDA.Schizophrenia and the pan/album incontaining class of cortical local circuit neurons.Am J Psychiatry.1997154101310159210755
  • HashimotoT.VolkDW.EgganSM.et al.Gene expression deficits in a subclass of GABA neurons in the prefrontal cortex of subjects with schizophrenia.J Neurosci.2003236315632612867516
  • WooT-U.WhiteheadRE.MelchitzkyDS.LewisDA.A subclass of prefrontal gamma-aminobutyric acid axon terminals are selectively altered in schizophrenia.Proc Natl Acad Sci USA.199895534153469560277
  • NusserZ.SieghartW.BenkeD.FritschyJ-M.SomogyiP.Differential synaptic localization of two major y-aminobutyric acid type A receptor a subunits on hippocampal pyramidal cells.Proc Natl Acad Sci USA.19969311939119448876241
  • VolkDW.PierriJN.FritschyJ-M.AuhS.SampsonAR.LewisDA.Reciprocal alterations in pre- and postsynaptic inhibitory markers at chandelier cell inputs to pyramidal neurons in schizophrenia.Cereb Cortex.2002121063107012217970
  • CollinT.ChatM.LucasMG.et al.Developmental changes in parvalbumin regulate presynaptic Ca2+ signaling.J Neurosci.2005259610715634771
  • MullerM.FelmyF.SchwallerB.SchneggenburgerR.Parvalbumin is a mobile presynaptic Ca2+ buffer in the calyx of held that accelerates the decay of Ca2+ and short-term facilitation.J Neurosci.2007272261227117329423
  • VreugdenhilM.JefferysJG.CelioMR.SchwallerB.Parvalbumin-deficiency facilitates repetitive IPSCs and gamma oscillations in the hippocampus.J Neurophysiol.2003891414142212626620
  • OverstreetLS.WestbrookGL.Synapse density regulates independence at unitary inhibitory synapses.J Neurosci.2003232618262612684447
  • LewisDA.HashimotoT.VolkDW.Cortical inhibitory neurons and schizophrenia.Nat Rev Neurosci.2005631232415803162
  • CondéF.LundJS.JacobowitzDM.BaimbridgeKG.LewisDA.Local circuit neurons immunoreactive for calretinin, calbindin D-28k, or parvalbumin in monkey prefrontal cortex: Distribution and morphology.J Comp Neurol.1994341951168006226
  • MorrisHM.HashimotoT.LewisDA.Alterations in somatostatin mRNA expression in the dorsolateral prefrontal cortex of subjects with schizophrenia or schizoaffective disorder.Cereb Coitex.20081815751587
  • OethKM.LewisDA.Cholecystokinin innervation of monkey prefrontal cortex: An immunohistochemical study.J Comp Neurol.19903011231371706355
  • EgganSM.LewisDA.Immunocytochemical distribution of the cannabinoid CB1 receptor in the primate neocortex: a regional and laminar analysis.Cereb Cortex.20071717519116467563
  • EgganSM.HashimotoT.LewisDA.Reduced cortical cannabinoid 1 receptor messenger RNA and protein expression in schizophrenia.Arch Gen Psychiatry.20086577278418606950
  • RaoSG.WilliamsGV.Goldman-RakicPS.Destruction and creation of spatial tuning by disinhibition: GABAA blockade of prefrontal cortical neurons engaged by working memory.J Neurosci.20002048549410627624
  • SawaguchiT.MatsumuraM.KubotaK.Delayed response deficits produced by local injection of bicuculline into the dorsolateral prefrontal cortex in Japanese macaque monkeys.Exp Brain Res.1989754574692744104
  • PouilleF.ScanzianiM.Enforcement of temporal fidelity in pyramidal cells by somatic feed-forward inhibition.Science.20012931159116311498596
  • PetersA.ProskauerCC.RibakCE.Chandelier neurons in rat visual cortex.J Comp Neurol.19822063974167096634
  • KlausbergerT.MagillPJ.MartonLF.et al.Brain-state- and cell-type specific firing of hippocampal interneurons in vivo.Nature.200342184484812594513
  • WhittingtonMA.TraubRD.Interneuron diversity series: inhibitory interneurons and network oscillations in vitro.Trends Neurosci.20032667668214624852
  • CardinJA.CarlenM.MeletisK.et al.Driving fast-spiking cells induces gamma rhythm and controls sensory responses.Nature.200945966366719396156
  • HowardMW.RizzutoDS.CaplanJB.et al.Gamma oscillations correlate with working memory load in humans.Cereb Cortex.2003131369137414615302
  • ChoRY.KoneckyRO.CarterCS.Impairments in frontal cortical gamma synchrony and cognitive control in schizophrenia.Proc Natl Acad Sci USA.2006103198781988317170134
  • HajosN.KatonaI.NaiemSS.et al.Cannabinoids inhibit hippocampal GABAergic transmission and network oscillations.Eur J Neurosci.2000123239324910998107
  • CondéF.LundJS.LewisDA.The hierarchical development of monkey visual cortical regions as revealed by the maturation of parvalbuminimmunoreactive neurons.Dev Brain Res.1996962612768922688
  • CruzDA.EgganSM.LewisDA.Postnatal development of pre- and postsynaptic GABA markers at chandelier cell inputs to pyramidal neurons in monkey prefrontal cortex.J Comp Neurol.200346538540012966563
  • LundJS.LewisDA.Local circuit neurons of developing and mature macaque prefrontal cortex: Golgi and immunocytochemical characteristics.J Comp Neurol.19933282823127678612
  • LoupF.WeinmannO.YonekawaY.AguzziA.WieserH-G.FritschyJM.A highly sensitive immunofluorescence procedure for analyzing the subcellular distribution of GABAA receptor subunits in the human brain.J Histochern Cytochem.19984611291139
  • KordeliE.LambertS.BennettV.Ankyrin G. A new ankyrin gene with neural-specific isoforms localized at the axonal initial segment and node of Ranvier.J Biol Chern.199527023522359
  • AngoF.Di CristoG.HigashiyamaH.BennettV.WuP.HuangZJ.Ankyrin-based subcellular gradient of neurofascin, an immunoglobulin family protein, directs GABAergic innervation at purkinje axon initial segment.Cell.200411925727215479642
  • YangY.OgawaY.HedstromKL.RasbandMN.beta IV spectrin is recruited to axon initial segments and nodes of Ranvier by ankyrinG.J Cell Biol.200717650951917283186
  • YangY.Lacas-GervaisS.MerestDK.SolimenaM.RasbandMN.BetalV spectrins are essential for membrane stability and the molecular organization of nodes of Ranvier.J Neurosci.2004247230724015317849
  • FritschyJM.HarveyRJ.SchwarzG.Gephyrin: where do we stand, where do we go?Trends Neurosci.20083125726418403029
  • CruzDA.LovalloEM.StocktonS.RasbandM.LewisDA.Postnatal development of synaptic structure proteins in pyramidal neuron axon initial segments in monkey prefrontal cortex.J Comp Neurol.200951435336719330819
  • HashimotoT.NguyenQL.RotaruD.et al.Protracted developmental trajectories of GABAA receptor alpha 1 and alpha 2 subunit expression in primate prefrontal cortex.Biol Psychiatry.2009651015102319249749
  • HashimotoT.ArionD.UngerT.et al.Alterations in GABA-related transcriptome in the dorsolateral prefrontal cortex of subjects with schizophrenia.Mol Psychiatry.20081314716117471287
  • CroneEA.WendelkenC.DonohueS.van LeijenhorstL.BungeSA.Neurocognitive development of the ability to manipulate information in working memory.Proc Natl Acad Sci USA.20061039315932016738055
  • LunaB.GarverKE.UrbanTA.LazarNA.SweeneyJA.Maturation of cognitive processes from late childhood to adulthood.Child Devel.2004751357137215369519
  • LewisDA.ChoRY.CarterCS.et al.Subunit-selective modulation of GABA type A receptor neurotransmission and cognition in schizophrenia.Am J Psychiatry.20081651585159318923067