REFERENCES

• YoungM.BenjaminB.WallisC.The mortality of widowers.Lancet.19631345445614044326
   PubMedGoogle Scholar
• HartC.HoleD.LawlorD.SmithG.LeverT.Effect of conjugal bereavement on mortality of the bereaved spouse in participants of the Renfrew/Paisley Study.J Epidemiol Community Health.20076145546017435215
   PubMed Web of Science ®Google Scholar
• ManorO.EisenbachZ.Mortality after spousal loss: are there sociodemographic differences?SocSciMed.200356405413
   Web of Science ®Google Scholar
• LichtensteinP.GatzM.BergS.A twin study of mortality after spousal bereavement.Psychol Med.1998286356439626719
   PubMed Web of Science ®Google Scholar
• JonesMP.BartropRW.ForcierL.PennyR.The long-term impact of bereavement upon spouse health: a 10-year follow-up.Acta Neuropsychiatries.201022212217
   PubMed Web of Science ®Google Scholar
• GenevroJL.MarshallT.MillerT.Report on bereavement and grief research.Death Stud.20042849157515317140
   PubMed Web of Science ®Google Scholar
• MartikainenP.ValkonenT.Mortality after the death of a spouse: rates and causes of death in a large finnish cohort.Am J Public Health.199686108710938712266
   PubMed Web of Science ®Google Scholar
• SchaeferC.QuesenberryCP Jr.WiS.Mortality following conjugal bereavement and the effects of a shared environment.Am J Epidemiol.1995141114211527771452
   PubMed Web of Science ®Google Scholar
• KhanferR.LordJ.PhillipsA.Neutrophil function and cortisol: DHEAS ratio in bereaved older adults.Brain Behav Immun.2011251182118621420485
   PubMed Web of Science ®Google Scholar
• IrwinM.DanielsM.RischS.BloomE.WeinerH.Plasma cortisol and natural killer cell activity during bereavement.Biol Psychiatry.1988241731783390497
   PubMed Web of Science ®Google Scholar
• SprattM.DenneyD.Immune variables, depression, and plasma cortisol over time in suddenly bereaved parents.J Neuropsychiatry Clin Neurosci.199132993061821246
   PubMed Web of Science ®Google Scholar
• GerraG.MontiD.PaneraiA.et al.Long-term immune-endocrine effects of bereavement: relationships with anxiety levels and mood.Psychiatry Res.200312114515814656449
   PubMed Web of Science ®Google Scholar
• BuckleyT.BartropR.McKinleyS.et al.Prospective study of early bereavement on psychological and behavioural cardiac risk factors.Intern Med J.20093937037819460057
   PubMed Web of Science ®Google Scholar
• NicolsonNA.Childhood parental loss and cortisol levels in adult men.Psychoneuroendocrinology.2004291012101815219652
   PubMed Web of Science ®Google Scholar
• FraserR.IngramMC.AndersonNH.MorrisonC.DaviesE.ConnellJM.Cortisol effects on body mass, blood pressure, and cholesterol in the general population.Hypertension.1999331364136810373217
   PubMed Web of Science ®Google Scholar
• SegerstromS.MillerGE.Psychological stress and the human immune system: A meta-analytic study of 30 years of inquiry.Psychol Bull.200413060163015250815
   PubMed Web of Science ®Google Scholar
• BreierA.A.E. Bennett award paper. Experimental approaches to human stress research: assessment of neurobiological mechanisms of stress in volunteers and psychiatric patients.Biol Psychiatry.1989264384622551397
   PubMed Web of Science ®Google Scholar
• ValdimarsdottirU.HelgasonAR.FurstCJ.AdolfssonJ.SteineckG.Longterm effects of widowhood after terminal cancer: a Swedish nationwide follow-up.Scand J Public Health.200331313612623522
   PubMed Web of Science ®Google Scholar
• DoiY.MinowaM.OkawaM.UchiyamaM.Prevalence of sleep disturbance and hypnotic medication use in relation to sociodemographic factors in the general Japanese adult population.J Epidemiol.200010798610778031
   PubMedGoogle Scholar
• GermainA.CaroffK.BuysseDJ.ShearMK.Sleep quality in complicated grief.J Trauma Stress.20051834334616281231
   PubMed Web of Science ®Google Scholar
• ReynoldsCF 3rd.HochCC.BuysseDJ.et al.Electroencephalographic sleep in spousal bereavement and bereavement-related depression of late life.Biol Psychiatry.19923169821543799
   PubMed Web of Science ®Google Scholar
• PasternakRE.ReynoldsCF 3rd.HochCC.et al.Sleep in spousally bereaved elders with subsyndromal depressive symptoms.Psychiatry Res.19924343531438616
   PubMed Web of Science ®Google Scholar
• HallM.BuysseDJ.DewMA.PrigersonHG.KupferDJ.ReynoldsCF 3rd.Intrusive thoughts and avoidance behaviors are associated with sleep disturbances in bereavement-related depression.Depress Anxiety.199761061129442984
   PubMedGoogle Scholar
• ArmitageR.HoffmannR.Sleep EEG, depression and gender.Sleep Med Rev.2001523724612530989
   PubMed Web of Science ®Google Scholar
• ReynoldsC.KupferD.Sleep research in affective illness: state of the art circa 1987.Sleep.1987101992153306874
   PubMed Web of Science ®Google Scholar
• RiemannD.BergerM.VoderholzerU.Sleep and depression-results from psychobiological studies: an overview.Biol Psychol.2001576710311454435
   PubMed Web of Science ®Google Scholar
• RichardsonS.LundD.CasertaM.DudleyW.ObrayS.Sleep patterns in older bereaved spouses.Omega.200347361383
   Web of Science ®Google Scholar
• PrigersonH.BierhalsA.KaslS.et al.Traumatic grief as a risk factor for mental and physical morbidity.Am J Psychiatry.19971546166239137115
   PubMed Web of Science ®Google Scholar
• DewMA.HochCC.BuysseDJ.et al.Healthy older adults' sleep predicts all-cause mortality at 4 to 19 years of follow-up.Psychosom Med.200365637312554816
   PubMed Web of Science ®Google Scholar
• MonkTH.GermainA.ReynoldsCF.Sleep disturbance in bereavement.PsychiatrAnn.200838671675
   Google Scholar
• MillerGE.CohenS.Psychological interventions and immune system: a meta-analytic review and critique.Health Psychol.200120476311199066
   PubMed Web of Science ®Google Scholar
• BartropRW.LuckhurstE.LazarusL.KilohLG.PennyR.Depressed lymphocyte function after bereavement.Lancet.1977183483667339
   PubMed Web of Science ®Google Scholar
• SchleiferSJ.KellerSE.CamerinoM.ThorntonJC.SteinM.Suppression of lymphocyte stimulation following bereavement.JAMA.19832503743776854901
   PubMed Web of Science ®Google Scholar
• GoodkinK.FeasterDJ.TuttleR.et al.Bereavement is associated with time-dependent decrements in cellular immune function in asymptomatic human immunodeficiency virus type 1-seropositive homosexual men.Clin Diagn Lab Immunol.199631091188770514
   PubMedGoogle Scholar
• SprattML.DenneyDR.Immune variables, depression, and plasma cortisol over time in suddenly bereaved parents.J Neuropsychiatry Clin Neurosci.199132993061821246
   PubMed Web of Science ®Google Scholar
• IrwinM.DanielsM.BloomET.SmithTL.WeinerH.Life events, depressive symptoms, and immune function.Am J Psychiatry.19871444374412952025
   PubMed Web of Science ®Google Scholar
• LindstromTC.Immunity and health after bereavement in relation to coping.Scand J Psychol.1997382532599309955
   PubMed Web of Science ®Google Scholar
• LinnMW.LinnBS.JensenJ.Stressful events, dysphoric mood, and immune responsiveness.Psychol Rep.1984542192226718615
   PubMed Web of Science ®Google Scholar
• BuckleyT.Morel-KoppMC.WardC.et al.Inflammatory and thrombotic changes in early bereavement: a prospective evaluation.Eur J Cardiovasc Prev Rehabil. In press.
   Google Scholar
• PhillipsAN.NeatonJD.CookDG.GrimmRH.ShaperAG.Leukocyte count and risk of major coronary heart disease events.Am J Epidemiol.199213659701415132
   PubMed Web of Science ®Google Scholar
• RidkerPM.CushmanM.StampferMJ.TracyRP.HennekensCH.Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men.N Engl J Med.19973369739799077376
   PubMed Web of Science ®Google Scholar
• BuckleyT.MihailidouA.BartropR.et al.Haemodynamic changes during early bereavement: potential contribution to increased cardiovascular risk.Heart Lung Circulation.2011209198
   PubMed Web of Science ®Google Scholar
• O'ConnorM.AllenJ.KaszniakA.Autonomic and emotion regulation in bereavement and depression.J Psychosom Res.20025218318511943236
   PubMed Web of Science ®Google Scholar
• GummingJ.OlphinT.LawM.Self-reported psychological states and physiological responses to different types of motivational general imagery.J Sport Exerc Psychol.20072962964418089896
   PubMedGoogle Scholar
• KizilbashMA.DaviglusML.DyerAR.et al.Relation of heart rate with cardiovascular disease in normal-weight individuals: the Chicago Heart Association Detection Project in Industry.Prev Cardiol.20081114114718607149
   PubMedGoogle Scholar
• PalatiniP.JuliusS.Elevated heart rate: a major risk factor for cardiovascular disease.Clin Exp Hypertens.20042663764415702618
   PubMed Web of Science ®Google Scholar
• HeidlandUE.StrauerBE.Left ventricular muscle mass and elevated heart rate are associated with coronary plaque disruption.Circulation.20011041477148211571239
   PubMed Web of Science ®Google Scholar
• AronowWS.AhnC.MercandoAD.EpsteinS.Association of average heart rate on 24-hour ambulatory electrocardiograms with incidence of new coronary events at 48-month follow-up in 1,311 patients (mean age 81 years) with heart disease and sinus rhythm.Am J Cardiol.199678117511768914888
   PubMed Web of Science ®Google Scholar
• ToflerGH.MullerJE.Triggering of acute cardiovascular disease and potential preventive strategies.Circulation.20061141863187217060396
   PubMed Web of Science ®Google Scholar
• GrantI.AdlerKA.PattersonTL.DimsdaleJE.ZieglerMG.IrwinMR.Health consequences of Alzheimer's caregiving transitions: effects of placement and bereavement.Psychosom Med.20026447748612021421
   PubMed Web of Science ®Google Scholar
• SanticZ.LukicA.SesarD.MilicevicS.IlakovacV.Long-term follow-up of blood pressure in family members of soldiers killed during the war in Bosnia and Herzegovina.Croat Med J.20064741642316758520
   PubMed Web of Science ®Google Scholar
• LewingtonS.ClarkeR.QizilbashN.PetoR.CollinsR.Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies.Lancet.20023601903191312493255
   PubMed Web of Science ®Google Scholar
• von KanelR.HeppU.TraberR.et al.Measures of endothelial dysfunction in plasma of patients with posttraumatic stress disorder.Psychiatry Res.200815836337318252265
   PubMed Web of Science ®Google Scholar
• Morel-KoppMC.McLeanL.ChenQ.et al.The association of depression with platelet activation: evidence for a treatment effect.J Thromb Haemost.2009757358119192119
   PubMed Web of Science ®Google Scholar
• WangJ.ZhangS.JinY.QinG.YuL.ZhangJ.Elevated levels of plateletmonocyte aggregates and related circulating biomarkers in patients with acute coronary syndrome.IntJ Cardiol.200711536136516887214
   PubMed Web of Science ®Google Scholar
• Kucharska-NewtonAM.CouperDJ.et al.Hemostasis, inflammation, and fatal and nonfatal coronary heart disease: long-term follow-up of the atherosclerosis risk in communities (ARIC) cohort.Arterioscier Thromb Vase Biol.20092921822190
   PubMed Web of Science ®Google Scholar
• MarkovitzJH.ShusterJL.ChitwoodWS.MayRS.TolbertLC.Platelet activation in depression and effects of sertraline treatment: an open-label study.Am J Psychiatry.20001 571006100810831484
   PubMedGoogle Scholar
• ServossSJ.JanuzziJL.MullerJE.Triggers of acute coronary syndromes.Prog Cardiovasc Dis.20024436938012024335
   PubMed Web of Science ®Google Scholar
• GoodkinK.FeasterDJ.AsthanaD.et al.A bereavement support group intervention is longitudinally associated with salutary effects on the CD4 cell count and number of physician visits.Clin Diagn Lab immunol.199853823919605995
   PubMedGoogle Scholar
• GermainA.ShearK.MonkTH.et al.Treating complicated grief: effects on sleep quality.Behav Sleep Med.2006415216316879079
   PubMedGoogle Scholar
• PrigersonHG.MaciejewskiPK.ReynoldsCF 3rd.et al.Inventory of Complicated Grief: a scale to measure maladaptive symptoms of loss.Psychiatry Res.19955965798771222
   PubMed Web of Science ®Google Scholar
• CarterPA.MikanSQ.SimpsonC.A feasibility study of a two-session home-based cognitive behavioral therapy-insomnia intervention for bereaved family caregivers.Palliat Support Care.2009719720619538802
   PubMedGoogle Scholar
• PasternakRE.ReynoldsCF 3rd.HouckPR.et al.Sleep in bereavementrelated depression during and after pharmacotherapy with nortriptyline.J Geriatr Psychiatry Neurol.1994769738204191
   PubMed Web of Science ®Google Scholar
• TaylorMP.ReynoldsCF 3rd.FrankE.et al.EEG sleep measures in laterlife bereavement depression, a randomized, double-blind, placebo-controlled evaluation of nortriptyline.Am J Geriatr Psychiatry.1999741479919319
   PubMed Web of Science ®Google Scholar
• BeemEE.HooijkaasH.CleirenMH.et al.The immunological and psychological effects of bereavement: does grief counseling really make a difference? A pilot study.Psychiatry Res.199985819310195319
   PubMed Web of Science ®Google Scholar
• KangHY.YooYS.Effects of a bereavement intervention program in middle-aged widows in Korea.Arch Psychiatr Nurs.20072113214017556106
   PubMed Web of Science ®Google Scholar
• GoodkinK.BaldewiczTT.AsthanaD.et al.A bereavement support group intervention affects plasma burden of human immunodeficiency virus type 1. Report of a randomized controlled trial.J Hum Virol.20014445411213933
   PubMedGoogle Scholar
• WardAW.Mortality of bereavement.BMJ.197617007021252892
   PubMed Web of Science ®Google Scholar
• ChristakisNA.IwashynaTJ.The health impact of health care on families: a matched cohort study of hospice use by decedents and mortality outcomes in surviving, widowed spouses.Soc Sci Med.20035746547512791489
   PubMed Web of Science ®Google Scholar