REFERENCES

• Wirz-JusticeA.TerrnanM.Chronotherapeutics (light and wake therapy) as a class of interventions for affective disorders.Handb Clin Neurol.201210669771322608653
   PubMedGoogle Scholar
• Wirz-JusticeA.BenedettiF.BergerM.et al.Chronotherapeutics (light and wake therapy) in affective disorders.Psychol Med.20053593994416045060
   PubMed Web of Science ®Google Scholar
• BenedettiF.BarbiniB.ColomboC.SmeraldiE.Chronotherapeutics in a psychiatric ward.Sleep Med Rev.20071150952217689120
   PubMed Web of Science ®Google Scholar
• Wirz-JusticeA.BenedettiF.TermanM.Chronotherapeutics for Affective Disorders. A Clinician's Manual for Light and VJake Therapy. Basel, Switzerland: Karger; 2009.
   Google Scholar
• Wirz-JusticeA.Chronobiology and mood disorders.Dialogues Clin Neurosci.2003531532522033593
   PubMedGoogle Scholar
• BenedettiF.BarbiniB.CamporiE.ColomboC.SmeraldiE.Patterns of mood variation during antidepressant treatment.J Affect Disord.1998491331399609677
   PubMed Web of Science ®Google Scholar
• BenedettiF.ColomboC.BarbiniB.CamporiE.SmeraldiE.Morning sunlight reduces length of hospitalization in bipolar depression.J Affect Disord.20016222122311223110
   PubMed Web of Science ®Google Scholar
• BauerM.PfennigA.LindenM.SmolkaMN.NeuP.AdliM.Efficacy of an algorithm-guided treatment compared with treatment as usual: a randomized, controlled study of inpatients with depression.J Clin Psychopharmacol.20092932733319593170
   PubMed Web of Science ®Google Scholar
• BauerM.GlennT.WhybrowPC.et al.Changes in self-reported sleep duration predict mood changes in bipolar disorder.Psychol Med.2008381069107118377675
   PubMed Web of Science ®Google Scholar
• LeibenluftE.WehrTA.Is sleep deprivation useful in the treatment of depression?Am J Psychiatry.19921491591681734735
   PubMed Web of Science ®Google Scholar
• WuJC.BunneyWE.The biological basis of an antidepressant response to sleep deprivation and relapse: review and hypothesis.Am J Psychiatry.199014714212403471
   PubMed Web of Science ®Google Scholar
• PostRM.LeverichGS.AltshulerLLet al.Differential clinical characteristics, medication usage, and treatment response of bipolar disorder in the US versus The Netherlands and Germany.Int Clin Psychopharmacol.2011269610621178634
   PubMed Web of Science ®Google Scholar
• AltshulerLL.KupkaRW.HellemannG.et al.Gender and depressive symptoms in 711 patients with bipolar disorder evaluated prospectively in the Stanley Foundation bipolar treatment outcome network.Am J Psychiatry.201016770871520231325
   PubMed Web of Science ®Google Scholar
• KupkaRW.AltshulerLL.NolenWA.et al.Three times more days depressed than manic or hypomanic in both bipolar I and bipolar II disorder.Bipolar Disord.2007953153517680925
   PubMed Web of Science ®Google Scholar
• PostRM.LeverichGS.AltshulerLL.et al.Relationship of prior antidepressant exposure to long-term prospective outcome in bipolar I disorder outpatients.J Clin Psychiatry.20127392493022480597
   PubMed Web of Science ®Google Scholar
• FryeMA.HellemanG.McElroySL.et al.Correlates of treatment-emergent mania associated with antidepressant treatment in bipolar depression.Am J Psychiatry.200916616417219015231
   PubMed Web of Science ®Google Scholar
• GaoK.KempDE.GanocySJ.et al.Treatment-emergent mania/hypomania during antidepressant monotherapy in patients with rapid cycling bipolar disorder.Bipolar Disord.20081090791519594506
   PubMed Web of Science ®Google Scholar
• AltshulerL.SuppesT.BlackD.et al.Impact of antidepressant discontinuation after acute bipolar depression remission on rates of depressive relapse at 1-year follow-up.Ami J Psychiatry.200316012521262
   PubMed Web of Science ®Google Scholar
• PostRM.AltshulerLL.FryeMA.et al.Complexity of pharmacologic treatment required for sustained improvement in outpatients with bipolar disorder.J Clin Psychiatry.2010711176118620923622
   PubMed Web of Science ®Google Scholar
• BenedettiF.ColomboC.Sleep deprivation in mood disorders.Neuropsychobiology.20116414115121811084
   PubMed Web of Science ®Google Scholar
• DibnerC.SchiblerU.AlbrechtU.The mammalian circadian timing system: organization and coordination of central and peripheral clocks.Annu Rev Physiol.20107251754920148687
   PubMed Web of Science ®Google Scholar
• McClungCA.Circadian rhythms and mood regulation: insights from pre-clinical models.Eur Neuropsychopharmacol.201121(suppl 4)S683S69321835596
   PubMed Web of Science ®Google Scholar
• JauharP.WellerMP.Psychiatric morbidity and time zone changes: a study of patients from Heathrow airport.Br J Psychiatry.19821402312357093591
   PubMed Web of Science ®Google Scholar
• YoungDM.Psychiatric morbidity in travelers to Honolulu, Hawaii.Cornpr Psychiatry.199536224228
   Google Scholar
• PflugB.TolleR.Therapy of endogenous depression using sleep deprivation. Practical and theoretical consequences.Nervenarzt.1971421171245550102
   PubMedGoogle Scholar
• SchilgenB.TolleR.Partial sleep deprivation as therapy for depression.Arch Gen Psychiatry.1980372672717189111
   PubMed Web of Science ®Google Scholar
• PflugB.TolleR.Disturbance of the 24-hour rhythm in endogenous depression and the treatment of endogenous depression by sleep deprivation.Int Pharmacopsychiatry.197161871964950570
   PubMedGoogle Scholar
• SchilgenB.TolleR.Partial sleep deprivation as therapy for depression.Arch Gen Psychiatry.1980372672717189111
   PubMed Web of Science ®Google Scholar
• GiedkeH.WormstallH.HaffnerHT.Therapeutic sleep deprivation in depressives, restricted to the two nocturnal hours between 3:00 and 5:00.Prog Neuropsychopharmacol Biol Psychiatry.19901437472405456
   PubMed Web of Science ®Google Scholar
• WehrTA.RosenthalNE.SackDA.GillinJC.Antidepressant effects of sleep deprivation in bright and dim light.Acta PsychiatrScand.198572161165
   PubMed Web of Science ®Google Scholar
• BenedettiF.DallaspeziaS.Cigala FulgosiM.et al.Actimetric evidence that CLOCK 3111 T/C SNP influences depressive insomnia and activity patterns in bipolar depression.Am J Med Genet B Neuropsychiatr Genet.200714463163517221848
   PubMed Web of Science ®Google Scholar
• VoderholzerU.Sleep deprivation and antidepressant treatment.Dialogues Clin Neurosci.2003536636922033748
   PubMedGoogle Scholar
• BarbiniB.ColomboC.BenedettiF.CamporiE.BellodiL.SmeraldiE.The unipolar-bipolar dichotomy and the response to sleep deprivation.Psychiatry Res.19987943509676825
   PubMed Web of Science ®Google Scholar
• van den BurgW.van den HoofdakkerRH.Total sleep deprivation on endogenous depression.Arch Gen Psychiatry.197532112111251101846
   PubMed Web of Science ®Google Scholar
• WiegandMH.LauerCJ.SchreiberW.Patterns of response to repeated total sleep deprivations in depression.J Affect Disord.20016425726011313092
   PubMed Web of Science ®Google Scholar
• KundermannB.StrateP.Hemmeter-SpernalJ.HuberMT.KriegJC.LautenbacherS.Mid-term effects of serial sleep deprivation therapy implemented in cognitive-behavioral treatment on the neuroendocrine response to clomipramine in patients with major depression.J Psychiatr Res.20094371172018930473
   PubMed Web of Science ®Google Scholar
• PapadimitriouGN.ChristodoulouGN.TrikkasGM.MalliarasDE.LykourasEP.StefanisCN.Sleep deprivation psychoprophylaxis in recurrent affective disorders.Bibl Psychiatr.198156617458886
   PubMedGoogle Scholar
• van BemmelAL.van den HoofdakkerRH.Maintenance of therapeutic effects of total sleep deprivation by limitation of subsequent sleep. A pilot study.Acta PsychiatrScand.198163453462
   PubMed Web of Science ®Google Scholar
• ChristodoulouGN.MalliarasDE.LykourasEP.PapadimitriouGN.StefanisCN.Possible prophylactic effect of sleep deprivation.Am J Psychiatry.1978135375376626237
   PubMed Web of Science ®Google Scholar
• PapadimitriouGN.ChristodoulouGN.KatsouyanniK.StefanisCN.Therapy and prevention of affective illness by total sleep deprivation.J Affect Disord.1993271071168440806
   PubMed Web of Science ®Google Scholar
• BenedettiF.BarbiniB.ColomboC.SmeraldiE.Chronotherapeutics in a psychiatric ward.Sleep Med Rev.20071150952217689120
   PubMed Web of Science ®Google Scholar
• BenedettiF.BarbiniB.LuccaA.CamporiE.ColomboC.SmeraldiE.Sleep deprivation hastens the antidepressant action of fluoxetine.Eur Arch Psychiatry Clin Neurosci.19972471001039177956
   PubMed Web of Science ®Google Scholar
• SmeraldiE.BenedettiF.BarbiniB.CamporiE.ColomboC.Sustained antidepressant effect of sleep deprivation combined with pindolol in bipolar depression - a placebo-controlled trial.Neuropsychopharmacology.19992038038510088139
   PubMed Web of Science ®Google Scholar
• BenedettiF.ColomboC.BarbiniB.CamporiE.SmeraldiE.Ongoing lithium treatment prevents relapse after total sleep deprivation.J Clin Psychopharmacol.1999 1924024510350030
   PubMed Web of Science ®Google Scholar
• ColomboC.LuccaA.BenedettiF.BarbiniB.CamporiE.SmeraldiE.Total sleep deprivation combined with lithium and light therapy in the treatment of bipolar depression: replication of main effects and interaction.Psychiatry Res.200095435310904122
   PubMed Web of Science ®Google Scholar
• BenedettiF.CamporiE.BarbiniB.FulgosiMC.ColomboC.Dopaminergic augmentation of sleep deprivation effects in bipolar depression.Psychiatry Res.200110423924611728613
   PubMed Web of Science ®Google Scholar
• BenedettiF.BarbiniB.FulgosiMC.et al.Combined total sleep deprivation and light therapy in the treatment of drug-resistant bipolar depression: acute response and long-term remission rates.J Clin Psychiatry.2005661535154016401154
   PubMed Web of Science ®Google Scholar
• BenedettiF.BernasconiA.BlasiV.et al.Neural and genetic correlates of antidepressant response to sleep deprivation: a fMRI study of moral valence decision in bipolar depression.Arch Gen Psychiatry.20076417918717283285
   PubMed Web of Science ®Google Scholar
• BenedettiF.DallaspeziaS.FulgosiMC.BarbiniB.ColomboC.SmeraldiE.Phase advance is an actimetric correlate of antidepressant response to sleep deprivation and light therapy in bipolar depression.Chronobiol Int.20072492193717994346
   PubMed Web of Science ®Google Scholar
• WehrTA.Sleep loss: a preventable cause of mania and other excited states.J Clin Psychiatry.198950 (suppl)8162689437
   PubMed Web of Science ®Google Scholar
• ColomboC.BenedettiF.BarbiniB.CamporiE.SmeraldiE.Rate of switch from depression into mania after therapeutic sleep deprivation in bipolar depression.Psychiatry Res.19998626727010482346
   PubMed Web of Science ®Google Scholar
• KripkeD.Photoperiodic mechanisms for depression and its treatment. In: Perris C, Struwe G, Jansson B, eds.Biological Psychiatry.Amsterdam, the Netherlands: Elsevier 198112491252
   Google Scholar
• KripkeDF.RischSC.JanowskyD.Bright white light alleviates depression.Psychiatry Res.1983101051126581487
   PubMed Web of Science ®Google Scholar
• LewyAJ.KernHA.RosenthalNE.WehrTA.Bright artificial light treatment of a manic-depressive patient with a seasonal mood cycle.Am J Psychiatry.1982139149614987137404
   PubMed Web of Science ®Google Scholar
• ParryBL.MaurerEL.Light treatment of mood disorders.Dialogues Clin Neurosci.2003535336522033495
   PubMedGoogle Scholar
• TermanM.TermanJS.Bright light therapy: side effects and benefits across the symptom spectrum.J Clin Psychiatry.19996079980810584776
   PubMed Web of Science ®Google Scholar
• TermanJS.TermanM.LoES.CooperTB.Circadian time of morning light administration and therapeutic response in winter depression.Arch Gen Psychiatry.200158697511146760
   PubMed Web of Science ®Google Scholar
• TermanM.TermanJS.Light therapy for seasonal and nonseasonal depression: efficacy, protocol, safety, and side effects.CNS Spectr.20051064766316041296
   PubMed Web of Science ®Google Scholar
• BenedettiF.ColomboC.PontiggiaA.BernasconiA.FloritaM.SmeraldiE.Morning light treatment hastens the antidepressant effect of citalopram: a placebo-controlled trial.J Clin Psychiatry.20036464865312823078
   PubMed Web of Science ®Google Scholar
• LewyAJ.LeflerBJ.EmensJS.BauerVK.The circadian basis of winter depression.Proc Natl Acad Sci U S A.20061037414741916648247
   PubMed Web of Science ®Google Scholar
• DallaspeziaS.BenedettiF.ColomboC.et al.Optimized light therapy for non-seasonal major depressive disorder: effects of timing and season.J Affect Disord.201213833734222325712
   PubMed Web of Science ®Google Scholar
• Wirz-JusticeA.GrawP.KrauchiK.et al.Light therapy in seasonal affective disorder is independent of time of day or circadian phase.Arch Gen Psychiatry.1993509299378250678
   PubMed Web of Science ®Google Scholar
• TermanM.Evolving applications of light therapy.Sleep Med Rev.20071149750717964200
   PubMed Web of Science ®Google Scholar
• GoldenRN.GaynesBN.EkstromRD.et al.The efficacy of light therapy in the treatment of mood disorders: a review and meta-analysis of the evidence.Am J Psychiatry.200516265666215800134
   PubMed Web of Science ®Google Scholar
• TuunainenA.KripkeDF.EndoT.Light therapy for non-seasonal depression.Cochrane Database Syst Rev.2004CD004050
   Google Scholar
• MartinyK.LundeM.UndenM.DamH.BechP.Adjunctive bright light in non-seasonal major depression: results from clinician-rated depression scales.Acta PsychiatrScand.2005112117125
   PubMed Web of Science ®Google Scholar
• KripkeDF.Light treatment for nonseasonal depression: speed, efficacy, and combined treatment.J Affect Disord.1998491091179609674
   PubMed Web of Science ®Google Scholar
• PraskoJ.BrunovskyM.LatalovaK.et al.Augmentation of antidepressants with bright light therapy in patients with comorbid depression and borderline personality disorder.Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub.201015435536121293548
   PubMed Web of Science ®Google Scholar
• MartinyK.LundeM.UndenM.DamH.BechP.The lack of sustained effect of bright light, after discontinuation, in non-seasonal major depression.Psychol Med.2006361247125216756691
   PubMed Web of Science ®Google Scholar
• MartinyK.LundeM.SimonsenC.et al.Relapse prevention by citalopram in SAD patients responding to 1 week of light therapy. A placebo-controlled study. ActaPsychiatrScand.2004109230234
   Google Scholar
• Wirz-JusticeA.BaderA.FrischU.et al.A randomized, double-blind, placebo-controlled study of light therapy for antepartum depression.J Clin Psychiatry.20117298699321535997
   PubMed Web of Science ®Google Scholar
• SondergaardMP.JardenJO.MartinyK.AndersenG.BechP.Dose response to adjunctive light therapy in citalopram-treated patients with post-stroke depression. A randomised, double-blind pilot study.Psychother Psychosom.20067524424816785774
   PubMed Web of Science ®Google Scholar
• DeltitoJA.MolineM.PollakC.MartinLY.MaremmaniI.Effects of phototherapy on non-seasonal unipolar and bipolar depressive spectrum disorders.J Affect Disord.1991232312371791269
   PubMed Web of Science ®Google Scholar
• DauphinaisDR.Rosenthal JZ, Terman M, DiFebo HM, Tuggle C, Rosenthal NE. Controlled trial of safety and efficacy of bright light therapy vs. negative air ions in patients with bipolar depression.Psychiatry Res.2012196576122424890
   PubMed Web of Science ®Google Scholar
• LewyAJ.NurnbergerJl Jr.WehrTA.et al.Supersensitivity to light: possible trait marker for manic-depressive illness.Am J Psychiatry.19851427257274003592
   PubMed Web of Science ®Google Scholar
• TermanM.SchlagerD.FairhurstS.PerlmanB.Dawn and dusk simulation as a therapeutic intervention.Biol Psychiatry.1989259669702720008
   PubMed Web of Science ®Google Scholar
• TermanM.TermanJS.Controlled trial of naturalistic dawn simulation and negative air ionization for seasonal affective disorder.Am J Psychiatry.20061632126213317151164
   PubMed Web of Science ®Google Scholar
• WehrTA.Wirz-JusticeA.GoodwinFK.DuncanW.GillinJC.Phase advance of the circadian sleep-wake cycle as an antidepressant.Science.1979206710713227056
   PubMed Web of Science ®Google Scholar
• SouetreE.SalvatiE.PringueyD.PlasseY.SavelliM.DarcourtG.Antidepressant effects of the sleep/wake cycle phase advance. Preliminary report.J Affect Disord.19871241462952693
   PubMed Web of Science ®Google Scholar
• GangwischJE.BabissLA.MalaspinaD.TurnerJB.ZammitGK.PosnerK.Earlier parental set bedtimes as a protective factor against depression and suicidal ideation.Sleep.2010339710620120626
   PubMed Web of Science ®Google Scholar
• BhattacharjeeY.Psychiatric research. Is internal timing key to mental health?Science.20073171488149017872420
   PubMed Web of Science ®Google Scholar
• BergerM.VollmannJ.HohagenF.et al.Sleep deprivation combined with consecutive sleep phase advance as a fast-acting therapy in depression: an open pilot trial in medicated and unmedicated patients.Am J Psychiatry.19971548708729167521
   PubMed Web of Science ®Google Scholar
• BenedettiF.BarbiniB.CamporiE.FulgosiMC.PontiggiaA.ColomboC.Sleep phase advance and lithium to sustain the antidepressant effect of total sleep deprivation in bipolar depression: new findings supporting the internal coincidence model? JPsychiatr Res.200135323329
   Web of Science ®Google Scholar
• VoderholzerU.ValeriusG.SchaererL.et al.Is the antidepressive effect of sleep deprivation stabilized by a three day phase advance of the sleep period? A pilot study.Eur Arch Psychiatry Clin Neurosci.2003253687212799743
   PubMed Web of Science ®Google Scholar
• WuJC.KelsoeJR.SchachatC.et al.Rapid and sustained antidepressant response with sleep deprivation and chronotherapy in bipolar disorder.Biol Psychiatry.20096629830119358978
   PubMed Web of Science ®Google Scholar
• MillanMJ.Multi-target strategies for the improved treatment of depressive states: conceptual foundations and neuronal substrates, drug discovery and therapeutic application.Pharmacol Ther.200611013537016522330
   PubMed Web of Science ®Google Scholar
• AdrienJ.Neurobiological bases for the relation between sleep and depression.Sleep Med Rev.2002634135112531125
   PubMed Web of Science ®Google Scholar
• GardnerJP.FornalCA.JacobsBL.Effects of sleep deprivation on serotonergic neuronal activity in the dorsal raphe nucleus of the freely moving cat.Neuropsychopharmacology.19971772819252982
   PubMed Web of Science ®Google Scholar
• Lopez-RodriguezF.WilsonCL.MaidmentNT.PolandRE.EngelJ.Total sleep deprivation increases extracellular serotonin in the rat hippocampus.Neuroscience.200312152353014522011
   PubMed Web of Science ®Google Scholar
• HeryF.PujolJF.LopezM.MaconJ.GlowinskiJ.Increased synthesis and utilization of serotonin in the central nervous system of the rat during paradoxical sleep deprivation.Brain Res.1970213914034318998
   PubMed Web of Science ®Google Scholar
• CramerH.TagliamonteA.TagliamonteP.Perez-CruetJ.GessaGL.Stimulation of brain serotonin turnover by paradoxical sleep deprivation in intact and hypophysectomized rats.Brain Res.1973543723754709153
   PubMed Web of Science ®Google Scholar
• AsikainenM.DeboerT.Porkka-HeiskanenT.StenbergD.ToblerI.Sleep deprivation increases brain serotonin turnover in the Djungarian hamster.Neurosci Lett.199519821248570087
   PubMed Web of Science ®Google Scholar
• MaudhuitC.JolasT.ChastanetM.HamonM.AdrienJ.Reduced inhibitory potency of serotonin reuptake blockers on central serotoninergic neurons in rats selectively deprived of rapid eye movement sleep.Biol Psychiatry.199640100010078915559
   PubMed Web of Science ®Google Scholar
• SantosR.CarliniEA.Serotonin receptor activation in rats previously deprived of REM sleep.Pharmacol Biochem Behav.1983185015076602989
   PubMed Web of Science ®Google Scholar
• HipolideDC.MoreiraKM.BarlowKB.WilsonAA.NobregaJN.TufikS.Distinct effects of sleep deprivation on binding to norepinephrine and serotonin transporters in rat brain.Prog Neuropsychopharmacol Biol Psychiatry.20052929730315694238
   PubMed Web of Science ®Google Scholar
• BasheerR.MagnerM.McCarleyRW.ShiromaniPJ.REM sleep deprivation increases the levels of tyrosine hydroxylase and norepinephrine transporter mRNA in the locus coeruleus.Brain Res Mol Brain Res.1998572352409675421
   PubMedGoogle Scholar
• TufikS.LindseyCJ.CarliniEA.Does REM sleep deprivation induce a supersensitivity of dopaminergic receptors in the rat brain?Pharmacology.19781698105201949
   PubMed Web of Science ®Google Scholar
• MogilnickaE.REM sleep deprivation changes behavioral response to catecholaminergic and serotonergic receptor activation in rats.Pharmacol Biochem Behav.1981151491517197363
   PubMed Web of Science ®Google Scholar
• Wirz-JusticeA.ToblerI.KafkaMS.et al.Sleep deprivation: effects on circadian rhythms of rat brain neurotransmitter receptors.Psychiatry Res.1981567766116257
   PubMed Web of Science ®Google Scholar
• ZwickerAP.CalilHM.The effects of REM sleep deprivation on striatal dopamine receptor sites.Pharmacol Biochem Behav.1986248098123012593
   PubMed Web of Science ®Google Scholar
• SalomonRM.DelgadoPL.LicinioJ.KrystalJH.HeningerGR.CharneyDS.Effects of sleep deprivation on serotonin function in depression.Biol Psychiatry.1994368408467893848
   PubMed Web of Science ®Google Scholar
• KasperS.SackDA.WehrTA.KickH.VollG.VieiraA.Nocturnal TSH and prolactin secretion during sleep deprivation and prediction of antidepressant response in patients with major depression.Biol Psychiatry.1988246316413167147
   PubMed Web of Science ®Google Scholar
• BaumgartnerA.RiemannD.BergerM.Neuroendocrinological investigations during sleep deprivation in depression. II. Longitudinal measurement of thyrotropin, TH, Cortisol, prolactin, GH, and LH during sleep and sleep deprivation.Biol Psychiatry.1990285695872171684
   PubMed Web of Science ®Google Scholar
• EbertD.FeistelH.KaschkaW.BarockaA.PirnerA.Single photon emission computerized tomography assessment of cerebral dopamine D2 receptor blockade in depression before and after sleep deprivationpreliminary results.Biol Psychiatry.1994358808858054411
   PubMed Web of Science ®Google Scholar
• GernerRH.PostRM.GillinJC.BunneyWE Jr.Biological and behavioral effects of one night's sleep deprivation in depressed patients and normals.J Psychiatr Res.1979152140219193
   PubMed Web of Science ®Google Scholar
• EbertD.AlbertR.HammonG.StrasserB.MayA.MerzA.Eye-blink rates and depression. Is the antidepressant effect of sleep deprivation mediated by the dopamine system?Neuropsychopharmacology.1996153323398887987
   PubMed Web of Science ®Google Scholar
• MullerHU.RiemannD.BergerM.MullerWE.The influence of total sleep deprivation on urinary excretion of catecholamine metabolites in major depression.Acta PsychiatrScand.1993881620
   PubMed Web of Science ®Google Scholar
• AminMM.KhalidR.KhanP.Relationship between sleep deprivation and urinary MHPG levels.Int Pharmacopsychiatry.19801581857440097
   PubMedGoogle Scholar
• MatussekN.RomischP.AckenheilM.MHPG excretion during sleep deprivation in endogenous depression.Neuropsychobiology.197732329895995
   PubMed Web of Science ®Google Scholar
• BenedettiF.SerrettiA.ColomboC.et al.Influence of a functional polymorphism within the promoter of the serotonin transporter gene on the effects of total sleep deprivation in bipolar depression.Am J Psychiatry.19991561450145210484962
   PubMed Web of Science ®Google Scholar
• BenedettiF.BarbiniB.BernasconiA.et al.Lithium overcomes the influence of 5-HTTLPR gene polymorphism on antidepressant response to sleep deprivation.J Clin Psychopharmacol.20082824925118344745
   PubMed Web of Science ®Google Scholar
• BenedettiF.ColomboC.SerrettiA.et al.Antidepressant effects of light therapy combined with sleep deprivation are influenced by a functional polymorphism within the promoter of the serotonin transporter gene.Biol Psychiatry.20035468769214512208
   PubMed Web of Science ®Google Scholar
• BenedettiF.BarbiniB.BernasconiA.et al.Serotonin 5-HT(2A) receptor gene variants influence antidepressant response to repeated total sleep deprivation in bipolar depression.Prog Neuropsychopharmacol Biol Psychiatry.2008321863186618801406
   PubMed Web of Science ®Google Scholar
• BenedettiF.BarbiniB.BernasconiA.et al.Acute antidepressant response to sleep deprivation combined with light therapy is influenced by the catechol-O-methyltransferase Val(108/158)Met polymorphism.J Affect Disord.2010121687219520435
   PubMed Web of Science ®Google Scholar
• BenedettiF.ColomboC.PirovanoA.MarinoE.SmeraldiE.The catechol-O-methyltransferase Val(108/158)Met polymorphism affects antidepressant response to paroxetine in a naturalistic setting.Psychopharmacology (Beri).2009203155160
   PubMed Web of Science ®Google Scholar
• BenedettiF.DallaspeziaS.ColomboC.LorenziC.PirovanoA.SmeraldiE.Effect of catechol-O-methyltransferase Val(108/158)Met polymorphism on antidepressant efficacy of fluvoxamine.Eur Psychiatry.20102547647820619611
   PubMed Web of Science ®Google Scholar
• SerrettiA.BenedettiF.ZanardiR.SmeraldiE.The influence of Serotonin Transporter Promoter Polymorphism (SERTPR) and other polymorphisms of the serotonin pathway on the efficacy of antidepressant treatments.Prog Neuro-Psychopharmacol Biol Psychiatry.20052910741084
   PubMed Web of Science ®Google Scholar
• SheltonRC.LoosenPT.Sleep deprivation accelerates the response to nortriptyline.Prog Neuropsychopharmacol Biol Psychiatry.1993171131238416598
   PubMed Web of Science ®Google Scholar
• GessaGL.PaniL.FaddaP.FrattaW.Sleep deprivation in the rat: an animal model of mania.Eur Neuropsychopharmacol.19955 (suppl)89938775765
   PubMed Web of Science ®Google Scholar
• Holsboer-TrachslerE.HemmeterU.HatzingerM.SeifritzE.GerhardU.HobiV.Sleep deprivation and bright light as potential augmenters of antidepressant drug treatment - neurobiological and psychometric assessment of course.J Psychiatr Res.1994283813997877117
   PubMed Web of Science ®Google Scholar
• aan het RotM.BenkelfatC.BoivinDB.YoungSN.Bright light exposure during acute tryptophan depletion prevents a lowering of mood in mildly seasonal women.Eur Neuropsychopharmacol.200818142317582745
   PubMed Web of Science ®Google Scholar
• DiazgranadosN.IbrahimL.BrutscheNE.et al.A randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression.Arch Gen Psychiatry.20106779380220679587
   PubMed Web of Science ®Google Scholar
• ZarateCA Jr.QuirozJA.SinghJB.et al.An open-label trial of the glutamate-modulating agent riluzole in combination with lithium for the treatment of bipolar depression.Biol Psychiatry.20055743043215705360
   PubMed Web of Science ®Google Scholar
• DashMB.DouglasCL.VyazovskiyVV.CirelliC.TononiG.Long-term homeostasis of extracellular glutamate in the rat cerebral cortex across sleep and waking states.J Neurosci.20092962062919158289
   PubMed Web of Science ®Google Scholar
• BenedettiF.CalabreseG.BernasconiA.et al.Spectroscopic correlates of antidepressant response to sleep deprivation and light therapy: a 3.0 Tesla study of bipolar depression.Psychiatry Res Neuroimaging.2009173238242
   PubMed Web of Science ®Google Scholar
• ElliottR.RubinszteinJS.SahakianBJ.DolanRJ.The neural basis of mood-congruent processing biases in depression.Arch Gen Psychiatry.20025959760412090812
   PubMed Web of Science ®Google Scholar
• WuJC.BuchsbaumM.BunneyWE Jr.Clinical neurochemical implications of sleep deprivation's effects on the anterior cingulate of depressed responders.Neuropsychopharmacology.200125 (suppl 5)S74S7811682278
   PubMed Web of Science ®Google Scholar
• GillinJC.BuchsbaumM.WuJ.ClarkC.BunneyW Jr.Sleep deprivation as a model experimental antidepressant treatment: findings from functional brain imaging.Depress Anxiety.200114374911568981
   PubMed Web of Science ®Google Scholar
• SchulzP.Biological clocks and the practice of psychiatry.Dialogues Clin Neurosci.2007923725517969862
   PubMedGoogle Scholar
• Wirz-JusticeA.Biological rhythm disturbances in mood disorders.Int Clin Psychopharmacol.200621 (suppl 1)S11S1516436934
   PubMed Web of Science ®Google Scholar
• SchiblerU.The daily timing of gene expression and physiology in mammals.Dialogues Clin Neurosci.2007925727217969863
   PubMedGoogle Scholar
• BencaR.DuncanMJ.FrankE.McClungC.NelsonRJ.VicenticA.Biological rhythms, higher brain function, and behavior: gaps, opportunities, and challenges.Brain Res Rev.200962577019766673
   PubMed Web of Science ®Google Scholar
• BenedettiF.The molecular clock as a target in the treatment of bipolar disorder.Neuropsychopharmacology.200530S63S64
   Google Scholar
• SprouseJ.Pharmacological modulation of circadian rhythms: a new drug target in psychotherapeutics.Expert Opin Ther Targets.20048253814996616
   PubMed Web of Science ®Google Scholar
• CiarleglioCM.ResuehrHE.McMahonDG.Interactions of the serotonin and circadian systems: nature and nurture in rhythms and blues.Neuroscience.201119781621963350
   PubMed Web of Science ®Google Scholar
• LambertGW.ReidC.KayeDM.JenningsGL.EslerMD.Effect of sunlight and season on serotonin turnover in the brain.Lancet.20023601840184212480364
   PubMed Web of Science ®Google Scholar
• RoybalK.TheoboldD.GrahamA.et al.Mania-like behavior induced by disruption of CLOCK.Proc Natl Acad Sci U S A.20071046406641117379666
   PubMed Web of Science ®Google Scholar
• McClungCA.SidiropoulouK.VitaternaM.et al.Regulation of dopaminergic transmission and cocaine reward by the Clock gene.Proc Natl AcadSciUSA.200510293779381
   PubMed Web of Science ®Google Scholar
• MukherjeeS.CoqueL.CaoJL.et al.Knockdown of Clock in the ventral tegmental area through RNA interference results in a mixed state of mania and depression-like behavior.Biol Psychiatry.20106850351120591414
   PubMed Web of Science ®Google Scholar
• BenedettiF.RadaelliD.BernasconiA.et al.Clock genes beyond the clock: CLOCK genotype biases neural correlates of moral valence decision in depressed patients. GenesBrain Behav.200872025
   Web of Science ®Google Scholar
• BenedettiF.DallaspeziaS.FulgosiMC.et al.Actimetric evidence that CLOCK 3111 T/C SNP influences sleep and activity patterns in patients affected by bipolar depression.Am J Med Genet B Neuropsychiatr Genet.2007144663163517221848
   PubMedGoogle Scholar
• SiegelJM.RogawskiMA.A function for REM sleep: regulation of noradrenergic receptor sensitivity.Brain Res.19884722132333066435
   PubMedGoogle Scholar
• PayneJL.QuirozJA.ZarateCA Jr.ManjiHK.Timing is everything: does the robust upregulation of noradrenergically regulated plasticity genes underlie the rapid antidepressant effects of sleep deprivation?Biol Psychiatry.20025292192612437933
   PubMed Web of Science ®Google Scholar
• LeeB.LiA.HansenKF.CaoR.YoonJH.ObrietanK.CREB influences timing and entrainment of the SCN circadian clock.J Biol Rhythms.20102541042021135157
   PubMed Web of Science ®Google Scholar
• St HilaireMA.GooleyJJ.KhalsaSB.KronauerRE.CzeislerCA.LockleySW.Human phase response curve (PRC) to a 1-hour pulse of bright white light.J Physiol.In press.
   Google Scholar
• KhalsaSB.JewettME.CajochenC.CzeislerCA.A phase response curve to single bright light pulses in human subjects.J Physiol.200354994595212717008
   PubMed Web of Science ®Google Scholar
• DeboerT.VansteenselMJ.DetariL.MeijerJH.Sleep states alter activity of suprachiasmatic nucleus neurons.Nat Neurosci.200361086109012958601
   PubMed Web of Science ®Google Scholar
• KhalsaSB.JewettME.CajochenC.CzeislerCA.A phase response curve to single bright light pulses in human subjects.J Physiol.200354994595212717008
   PubMed Web of Science ®Google Scholar
• BenedettiF.BarbiniB.FulgosiMC.et al.Combined total sleep deprivation and light therapy in the treatment of drug-resistant bipolar depression: Acute response and long-term remission rates.J Clin Psychiatry.2005661535154016401154
   PubMed Web of Science ®Google Scholar
• SprouseJ.BraseltonJ.ReynoldsL.Fluoxetine modulates the circadian biological clock via phase advances of suprachiasmatic nucleus neuronal firing.Biol Psychiatry.20066089689916631132
   PubMed Web of Science ®Google Scholar
• KrauchiK.CajochenC.MoriD.GrawP.Wirz-JusticeA.Early evening melatonin and S-20098 advance circadian phase and nocturnal regulation of core body temperature.Am J Physiol.1997272R1 178R1 1889038984
   PubMedGoogle Scholar
• WehrTA.DuncanWC Jr.SherL.et al.A circadian signal of change of season in patients with seasonal affective disorder.Arch Gen Psychiatry.2001581108111411735838
   PubMed Web of Science ®Google Scholar
• MasubuchiS.KataokaN.Sassone-CorsiP.OkamuraH.Mouse Periodl (mPER1) acts as a circadian adaptor to entrain the oscillator to environmental light/dark cycles by regulating mPER2 protein.J Neurosci.2005254719472415888647
   PubMed Web of Science ®Google Scholar
• AbeH.HonmaS.NamihiraM.et al.Clock gene expressions in the suprachiasmatic nucleus and other areas of the brain during rhythm splitting in CS mice.Brain Res Mol Brain Res.200187929911223163
   PubMedGoogle Scholar
• BenedettiF.RadaelliD.BernasconiA.et al.Clock genes beyond the clock: CLOCK genotype biases neural correlates of moral valence decision in depressed patients. GenesBrain Behav.200872025
   Web of Science ®Google Scholar
• KondratovRV.ShamannaRK.KondratovaAA.GorbachevaVY.AntochMP.Dual role of the CLOCK/BMAL1 circadian complex in transcriptional regulation.FASEBJ.200620530532
   PubMed Web of Science ®Google Scholar
• BenedettiF.DallaspeziaS.ColomboC.PirovanoA.MarinoE.SmeraldiE.A length polymorphism in the circadian clock gene Per3 influences age at onset of bipolar disorder.Neurosci Lett.200844518418718789374
   PubMed Web of Science ®Google Scholar
• BenedettiF.SerrettiA.ColomboC.et al.Influence of CLOCK gene polymorphism on circadian mood fluctuation and illness recurrence in bipolar depression.Am J Med Genet B Neuropsychiatr Genet.2003123B232614582141
   PubMed Web of Science ®Google Scholar
• DallaspeziaS.LorenziC.PirovanoA.ColomboC.SmeraldiE.BenedettiF.Circadian clock gene Per3 variants influence the postpartum onset of bipolar disorder.Eur Psychiatry.20112613814021316201
   PubMed Web of Science ®Google Scholar
• litakaC.MiyazakiK.AkaikeT.IshidaN.A role for glycogen synthase kinase3beta in the mammalian circadian clock. J S/o/Chem 20052802939729402
   Google Scholar
• GrimesCA.JopeRS.The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling.Prog Neurobiol.20016539142611527574
   PubMed Web of Science ®Google Scholar
• KockeritzL.DobleB.PatelS.WoodgettJR.Glycogen synthase kinase3 — an overview of an over-achieving protein kinase.Curr Drug Targets.200671377138817100578
   PubMed Web of Science ®Google Scholar
• FordeJE.DaleTC.Glycogen synthase kinase 3: a key regulator of cellular fate.Cell Mol Life Sci.2007641930194417530463
   PubMed Web of Science ®Google Scholar
• ManjiHK.MooreGJ.RajkowskaG.ChenG.Neuroplasticity and cellular resilience in mood disorders.Mol Psychiatry.2000557859311126389
   PubMed Web of Science ®Google Scholar
• GouldTD.ManjiHK.Glycogen synthase kinase-3: a putative molecular target for lithium mimetic drugs.Neuropsychopharmacology.2005301223123715827567
   PubMed Web of Science ®Google Scholar
• BeaulieuJM.ZhangX.RodriguizRM.et al.Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency.Proc Natl Acad Sci U S A.20081051333133818212115
   PubMed Web of Science ®Google Scholar
• BeaulieuJM.GainetdinovRR.CaronMG.Akt/GSK3 signaling in the action of psychotropic drugs.Annu Rev Pharmacol Toxicol.20094932734718928402
   PubMed Web of Science ®Google Scholar
• BenedettiF.BernasconiA.LorenziC.et al.A single nucleotide polymorphism in glycogen synthase kinase 3-beta promoter gene influences onset of illness in patients affected by bipolar disorder.Neurosci Lett.2004355374014729229
   PubMed Web of Science ®Google Scholar
• BenedettiF.SerrettiA.PontiggiaA.et al.Long-term response to lithium salts in bipolar illness is influenced by the glycogen synthase kinase 3-beta -50 T/C SNP.Neurosci Lett.2005376515515694273
   PubMed Web of Science ®Google Scholar
• AdliM.HollindeDL.StammT.Hollindeet al.Response to lithium augmentation in depression is associated with the glycogen synthase kinase 3-beta -50T/C single nucleotide polymorphism.Biol Psychiatry.2007621295130217628506
   PubMed Web of Science ®Google Scholar
• BenedettiF.SerrettiA.ColomboC.LorenziC.TubazioV.SmeraldiE.A glycogen synthase kinase 3-beta promoter gene single nucleotide polymorphism is associated with age at onset and response to total sleep deprivation in bipolar depression.Neurosci Lett.200436812312615351432
   PubMed Web of Science ®Google Scholar
• BenedettiF.DallaspeziaS.LorenziC.et al.Gene-gene interaction of glycogen synthase kinase 3-beta and serotonin transporter on human antidepressant response to sleep deprivation.J Affect Disord.201213651451922119086
   PubMed Web of Science ®Google Scholar
• SchloesserRJ.MartinowichK.ManjiHK.Mood-stabilizing drugs: mechanisms of action.Trends Neurosci.201235364622217451
   PubMed Web of Science ®Google Scholar
• TononiG.CirelliC.Sleep function and synaptic homeostasis.Sleep Med Rev.200610496216376591
   PubMed Web of Science ®Google Scholar
• MassiminiM.FerrarelliF.HuberR.EsserSK.SinghH.TononiG.Breakdown of cortical effective connectivity during sleep.Science.20053092228223216195466
   PubMed Web of Science ®Google Scholar
• TononiG.CirelliC.Sleep and synaptic homeostasis: a hypothesis.Brain Res Bull.20036214315014638388
   PubMed Web of Science ®Google Scholar
• HuberR.MakiH.RosanovaM.et al.Human cortical excitability increases with time awake.Cereb Cortex. Epub ahead of print: February 7,2012
   Google Scholar
• VyazovskiyW.CirelliC.Pfister-GenskowM.FaragunaU.TononiG.Molecular and electrophysiological evidence for net synaptic potentiation in wake and depression in sleep.Nat Neurosci.20081120020818204445
   PubMed Web of Science ®Google Scholar