REFERENCES

• Insel TR. Rethinking schizophrenia.Nature.201046818719321068826
   PubMed Web of Science ®Google Scholar
• RapoportJL.GieddJN.GogtayN.Neurodevelopmental model of schizophrenia: update 2012.Mol Psychiatry.2012171228123822488257
   PubMed Web of Science ®Google Scholar
• AhnK.GotayN.AndersenTM.et alHigh rate of disease-related copy number variations in childhood onset schizophrenia.Mol Psychiatry. doi:10.1038/mp.2013.59.2013
   Google Scholar
• MalhotraD.SebatJ.CNVs: harbingers of a rare variant revolution in psychiatric genetics.Cell.20121481223124122424231
   PubMed Web of Science ®Google Scholar
• WalshT.McClellanJM.McCarthySE.et alRare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia.Science.200832053954318369103
   PubMed Web of Science ®Google Scholar
• XuB.lonita-LazaI.RoosJL.et alDe novo gene mutations highlight patterns of genetic and neural complexity in schizophrenia.Nat Genet.2012441365136923042115
   PubMed Web of Science ®Google Scholar
• O'DonnellK.O'ConnorTG.GloverV.Prenatal stress and neurodevelopment of the child: focus on the HPA axis and role of the placenta.Dev Neurosci.20093128529219546565
   PubMed Web of Science ®Google Scholar
• HeimC.ShugartM.CraigheadWE.NemeroffCB.Neurobiological and psychiatric consequences of child abuse and neglect.Dev Psychobiol.20105267169020882586
   PubMed Web of Science ®Google Scholar
• LupienSJ.McEwenBS.GunnarMR.HeimC.Effects of stress throughout the lifespan on the brain, behaviour and cognition.Nat. Rev Neurosci.20091043444519401723
   PubMed Web of Science ®Google Scholar
• BonninA.GoedenN.ChenK.et alA transient placental source of serotonin for the fetal forebrain.Nature.201147234735021512572
   PubMed Web of Science ®Google Scholar
• YavaroneMS.ShueyDL.SadlerTW.LauderJM.Serotonin uptake in the ectoplacental cone and placenta of the mouse.Placenta.1993141491618506248
   PubMed Web of Science ®Google Scholar
• CoteF.FlignyC.BayardE.et alMaternal serotonin is crucial for murine embryonic development.Proc Natl Acad Sci U S A.200710432933417182745
   PubMed Web of Science ®Google Scholar
• KiyasovaV.GasparP.Development of raphe serotonin neurons from specification to guidance.Eur J Neurosci.2011341553156222103413
   PubMed Web of Science ®Google Scholar
• LidovHG.GrzannaR.MolliverME.The serotonin innervation of the cerebral cortex in the rat-an immunohistochemical analysis.Neuroscience.198052072276990293
   PubMed Web of Science ®Google Scholar
• VitalisT.AnsorgeMS.DayerAG.Serotonin homeostasis and serotonin receptors as actors of cortical construction: special attention to the 5-HT3A and 5-HT6 receptor subtypes.Front Cell Neurosci.201379323801939
   PubMed Web of Science ®Google Scholar
• HannonJ.HoyerD.Molecular biology of 5-HT receptors.Behav Brain Res.200819519821318571247
   PubMed Web of Science ®Google Scholar
• BonninA.PengW.HewlettW.LevittP.Expression mapping of 5-HT1 serotonin receptor subtypes during fetal and early postnatal mouse forebrain development.Neuroscience.200614178179416824687
   PubMed Web of Science ®Google Scholar
• Narboux-NemeN.PavoneLM.AvalloneL.ZhuangX.GasparP.Serotonin transporter transgenic (SERT(cre)) mouse line reveals developmental targets of serotonin specific reuptake inhibitors (SSRIs).Neuropharmacology.200855994100518789954
   PubMed Web of Science ®Google Scholar
• LebrandC.CasesO.AdelbrechtC.et alTransient uptake and storage of serotonin in developing thalamic neurons.Neuron.1996178238358938116
   PubMed Web of Science ®Google Scholar
• CasesO.VitalisT.SeifI.De MaeyerE.SoteloC.GasparP.Lack of barrels in the somatosensory cortex of monoamine oxidase A-deficient mice: role of a serotonin excess during the critical period.Neuron.1996162973078789945
   PubMed Web of Science ®Google Scholar
• VerneyC.LebrandC.GasparP.Changing distribution of monoaminergic markers in the developing human cerebral cortex with special emphasis on the serotonin transporter.Anat Rec.2002267879311997877
   PubMedGoogle Scholar
• LeeS.Hjerling-LefflerJ.ZaghaE.FishellG.RudyB.The largest group of superficial neocortical GABAergic interneurons expresses ionotropic serotonin receptors.J Neurosci.201030167961680821159951
   PubMed Web of Science ®Google Scholar
• LambeEK.FillmanSG.WebsterMJ.Shannon WeickertC.Serotonin receptor expression in human prefrontal cortex: balancing excitation and inhibition across postnatal development.PLoS One.20116e2279921829518
   PubMed Web of Science ®Google Scholar
• PersicoAM.MengualE.MoessnerR.et alBarrel pattern formation requires serotonin uptake by thalamocortical afferents, and not vesicular monoamine release.J Neurosci.2001216862687311517274
   PubMed Web of Science ®Google Scholar
• RebsamA.SeifI.GasparP.Refinement of thalamocortical arbors and emergence of barrel domains in the primary somatosensory cortex: a study of normal and monoamine oxidase a knock-out mice.J Neurosci.2002228541855212351728
   PubMed Web of Science ®Google Scholar
• SalichonN.GasparP.UptonAL.et alExcessive activation of serotonin (5-HT) 1B receptors disrupts the formation of sensory maps in monoamine oxidase a and 5-HT transporter knock-out mice.J Neurosci.20012188489611157075
   PubMed Web of Science ®Google Scholar
• BonninA.ToriiM.WangL.RakicP.LevittP.Serotonin modulates the response of embryonic thalamocortical axons to netrin-1.Nat Neurosci.20071058859717450135
   PubMed Web of Science ®Google Scholar
• MarinO.ValienteM.GeX.TsaiLH.Guiding neuronal cell migrations.Cold Spring Harb Perspect Biol.20102a00183420182622
   PubMed Web of Science ®Google Scholar
• ValienteM.MarinO.Neuronal migration mechanisms in development and disease.Curr Opin Neurobiol.201020687820053546
   PubMed Web of Science ®Google Scholar
• MarinO.Interneuron dysfunction in psychiatric disorders.Nat Rev Neurosci.20121310712022251963
   PubMed Web of Science ®Google Scholar
• StevensHE.SuT.YanagawaY.VaccarinoFM.Prenatal stress delays inhibitory neuron progenitor migration in the developing neocortex.Psychoneuroendocrinology.20133850952122910687
   PubMed Web of Science ®Google Scholar
• RiccioO.PotterG.WalzerC.et alExcess of serotonin affects embryonic interneuron migration through activation of the serotonin receptor 6.Mol Psychiatry.20091428029018663366
   PubMed Web of Science ®Google Scholar
• RiccioO.JacobshagenM.GoldingB.et alExcess of serotonin affects neocortical pyramidal neuron migration.Transl Psychiatry.20111e4722833193
   PubMed Web of Science ®Google Scholar
• AltamuraC.Dell'AcquaML.MoessnerR.MurphyDL.LeschKP.PersicoAM.Altered neocortical cell density and layer thickness in serotonin transporter knockout mice: a quantitation study.Cereb Cortex.2007171394140116905592
   PubMed Web of Science ®Google Scholar
• MeffreJ.Chaumont-DubelS.Mannoury la CourC.et al5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia.EMBO Mol Med.201241043105623027611
   PubMed Web of Science ®Google Scholar
• LevittP.CampbellDB.The genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disorders.J Clin invest.200911974775419339766
   PubMed Web of Science ®Google Scholar
• NietzerSL.BonnM.JansenF.et alSerotonin transporter knockout and repeated social defeat stress: Impact on neuronal morphology and plasticity in limbic brain areas.Behav Brain Res.2011220425421238500
   PubMed Web of Science ®Google Scholar
• WellmanCL.IzquierdoA.GarrettJE.et alImpaired stress-coping and fear extinction and abnormal corticolimbic morphology in serotonin transporter knock-out mice.J Neurosci.20072768469117234600
   PubMed Web of Science ®Google Scholar
• ArnstenAF.Stress signalling pathways that impair prefrontal cortex structure and function.Nat Rev Neurosci.20091041042219455173
   PubMed Web of Science ®Google Scholar
• ChameauP.IntaD.VitalisT.MonyerH.WadmanWJ.van HooftJA.The N-terminal region of reelin regulates postnatal dendritic maturation of cortical pyramidal neurons.Proc Natl Acad Sci U S A.20091067227723219366679
   PubMed Web of Science ®Google Scholar
• Smit-RigterLA.NoorlanderCW.von OerthelL.ChameauP.SmidtMP.van HooftJA.Prenatal fluoxetine exposure induces life-long serotonin 5HT(3) receptor-dependent cortical abnormalities and anxiety-like behaviour.Neuropharmacology.20116286587021964434
   PubMed Web of Science ®Google Scholar
• SmidtMP.AsbreukCH.CoxJJ.ChenH.JohnsonRL.BurbachJP.A second independent pathway for development of mesencephalic dopaminergic neurons requires Lmxlb.Nat Neurosci.2000333734110725922
   PubMed Web of Science ®Google Scholar
• AleninaN.KikicD.TodirasM.et alGrowth retardation and altered autonomic control in mice lacking brain serotonin.Proc Natl Acad Sci U S A.2009106103321033719520831
   PubMed Web of Science ®Google Scholar
• HendricksTJ.FyodorovDV.WegmanLJ.et alPet-1 ETS gene plays a critical role in 5-HT neuron development and is required for normal anxietylike and aggressive behavior.Neuron.20033723324712546819
   PubMed Web of Science ®Google Scholar
• Narboux-NemeN.AngenardG.MosienkoV.et alPostnatal growth defects in mice with constitutive depletion of central serotonin.ACS Chem Neurosci.2013417118123336056
   PubMed Web of Science ®Google Scholar
• GutknechtL.AraragiN.MerkerS.et alImpacts of brain serotonin deficiency following Tph2 inactivation on development and raphe neuron serotonergic specification.PLoS One.20127e4315722912815
   PubMed Web of Science ®Google Scholar
• MigliariniS.PaciniG.PelosiB.LunardiG.PasqualettiM.Lack of brain serotonin affects postnatal development and serotonergic neuronal circuitry formation.Mol Psychiatry. 2012;doi:10.1038/mp. 2012. 128.
   Google Scholar
• WaiderJ.ProftF.LanglhoferG.AsanE.LeschKP.GutknechtL.GABA concentration and GABAergic neuron populations in limbic areas are differentially altered by brain serotonin deficiency in Tph2 knockout mice.Histochern Cell Biol.2013139267281
   PubMed Web of Science ®Google Scholar
• NoorlanderCW.VerversFF.NikkelsPG.van EchteldCJ.VisserGH.SmidtMP.Modulation of serotonin transporter function during fetal development causes dilated heart cardiomyopathy and lifelong behavioral abnormalities.PLoS ONE.20083e278218716672
   PubMed Web of Science ®Google Scholar
• AnsorgeMS.ZhouM.LiraA.HenR.GingrichJA.Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice.Science.200430687988115514160
   PubMed Web of Science ®Google Scholar
• PopaD.LenaC.AlexandreC.AdrienJ.Lasting syndrome of depression produced by reduction in serotonin uptake during postnatal development: evidence from sleep, stress, and behavior.J Neurosci.2008283546355418385313
   PubMed Web of Science ®Google Scholar
• AnsorgeMS.MorelliE.GingrichJA.Inhibition of serotonin but not norepinephrine transport during development produces delayed, persistent perturbations of emotional behaviors in mice.J Neurosci.20082819920718171937
   PubMed Web of Science ®Google Scholar
• MurphyDL.LeschKP.Targeting the murine serotonin transporter: insights into human neurobiology.Nat Rev Neurosci.20089859618209729
   PubMed Web of Science ®Google Scholar
• KalueffAV.OlivierJD.NonkesLJ.HombergJR.Conserved role for the serotonin transporter gene in rat and mouse neurobehavioral endophenotypes.Neurosci Biobehav Rev.20103437338619698744
   PubMed Web of Science ®Google Scholar
• NonkesLJ.HombergJR.Perseverative instrumental and Pavlovian responding to conditioned stimuli in serotonin transporter knockout rats.Neurobiol Learn Mem.2013100485523261854
   PubMed Web of Science ®Google Scholar
• NarayananV.HeimingRS.JansenF.et alSocial defeat: impact on fear extinction and amygdala-prefrontal cortical theta synchrony in 5-HTT deficient mice.PLoS One.20116e2260021818344
   PubMed Web of Science ®Google Scholar
• AlexandreC.PopaD.FabreV.et alEarly life blockade of 5-hydroxytryptamine 1 A receptors normalizes sleep and depression-like behavior in adult knock-out mice lacking the serotonin transporter.J Neurosci.2006265554556416707806
   PubMed Web of Science ®Google Scholar
• GrossC.ZhuangX.StarkK.et alSerotoninIA receptor acts during development to establish normal anxiety-like behaviour in the adult.Nature.200241639640011919622
   PubMed Web of Science ®Google Scholar
• PageDT.KutiOJ.PrestiaC.SurM.Haploinsufficiency for Pten and Serotonin transporter cooperatively influences brain size and social behavior.Proc Natl Acad Sci U S A.20091061989199419208814
   PubMed Web of Science ®Google Scholar
• KinastK.PeetersD.KolkSM.SchubertD.HombergJR.Genetic and pharmacological manipulations of the serotonergic system in early life: neurodevelopmental underpinnings of autism-related behavior.Front Cell Neurosci.201377223781172
   PubMed Web of Science ®Google Scholar
• OlivierJD.VallesA.van HeeschF.et alFluoxetine administration to pregnant rats increases anxiety-related behavior in the offspring.Psychopharmacology (Berl)201121741943221487650
   PubMed Web of Science ®Google Scholar
• OberlanderTF.WarburtonW.MisriS.AghajanianJ.HertzmanC.Neonatal outcomes after prenatal exposure to selective serotonin reuptake inhibitor antidepressants and maternal depression using population-based linked health data.Arch Gen Psychiatry.20066389890616894066
   PubMed Web of Science ®Google Scholar
• GentileS.GalballyM.Prenatal exposure to antidepressant medications and neurodevelopmental outcomes: a systematic review.J Affect Disord .20111281920303599
   PubMed Web of Science ®Google Scholar
• CohenLS.AltshulerLL.HarlowBL.et alRelapse of major depression during pregnancy in women who maintain or discontinue antidepressant treatment.JAMA.200629549950716449615
   PubMed Web of Science ®Google Scholar
• CooperWO.WillyME.PontSJ.RayWA.Increasing use of antidepressants in pregnancy.Am J Obstet Gynecol.2007196544.e1544.e517547888
   PubMed Web of Science ®Google Scholar
• RamponoJ.ProudS.HackettLP.KristensenJH.llettKF.A pilot study of newer antidepressant concentrations in cord and maternal serum and possible effects in the neonate.Int J Neuropsychopharmacol.2004732933415035694
   PubMed Web of Science ®Google Scholar
• OberlanderTF.GingrichJA.AnsorgeMS.Sustained neurobehavioral effects of exposure to SSRI antidepressants during development: molecular to clinical evidence.Clin Pharmacol Ther.20098667267719890255
   PubMed Web of Science ®Google Scholar
• MulderEJ.VerversFF.de HeusR.VisserGH.Selective serotonin reuptake inhibitors affect neurobehavioral development in the human fetus.Neuropsychopharmacology.2011361961197121525859
   PubMed Web of Science ®Google Scholar
• RurakD.LimK.SandersA.BrainU.RiggsW.OberlanderTF.Third trimester fetal heart rate and doppler middle cerebral artery blood flow velocity characteristics during prenatal selective serotonin reuptake inhibitor (SSRI) exposure.Pediatr Res.2011709610121436759
   PubMed Web of Science ®Google Scholar
• OberlanderTF.WarburtonW.MisriS.AghajanianJ.HertzmanC.Effects of timing and duration of gestational exposure to serotonin reuptake inhibitor antidepressants: population-based study.Br J Psychiatry.200819233834318450656
   PubMed Web of Science ®Google Scholar
• CasperRC.FleisherBE.Lee-AncajasJC.et alFollow-up of children of depressed mothers exposed or not exposed to antidepressant drugs during pregnancy.J Pediatr.200314240240812712058
   PubMed Web of Science ®Google Scholar
• ColvinL.Slack-SmithL.StanleyFJ.BowerC.Early morbidity and mortality following in utero exposure to selective serotonin reuptake inhibitors: a population-based study in Western Australia.CNS Drugs.201226e11422712699
   PubMedGoogle Scholar
• LaineK.HeikkinenT.EkbladU.KeroP.Effects of exposure to selective serotonin reuptake inhibitors during pregnancy on serotonergic symptoms in newborns and cord blood monoamine and prolactin concentrations.Arch Gen Psychiatry.20036072072612860776
   PubMed Web of Science ®Google Scholar
• CasperRC.GillesAA.FleisherBE.BaranJ.EnnsG.LazzeroniLC.Length of prenatal exposure to selective serotonin reuptake inhibitor (SSRI) antidepressants: effects on neonatal adaptation and psychomotor development.Psychopharmacology (Berl).201121721121921499702
   PubMed Web of Science ®Google Scholar
• El MarrounH.JaddoeVW.HudziakJJ.et alMaternal use of selective serotonin reuptake inhibitors, fetal growth, and risk of adverse birth out-comes.Arch Gen Psychiatry.20126970671422393202
   PubMed Web of Science ®Google Scholar
• ChambersCD.Hernandez-DiazS.Van MarterLJ.et alSelective serotonin-reuptake inhibitors and risk of persistent pulmonary hypertension of the newborn.N Engl J Med.200635457958716467545
   PubMed Web of Science ®Google Scholar
• Moses-KolkoEL.BogenD.PerelJ.et alNeonatal signs after late in utero exposure to serotonin reuptake inhibitors: literature review and implications for clinical applications.JAMA.20052932372238315900008
   PubMed Web of Science ®Google Scholar
• WarburtonW.HertzmanC.OberlanderTF.A register study of the impact of stopping third trimester selective serotonin reuptake inhibitor exposure on neonatal health.Acta Psychiatr Scand.201012147147919878137
   PubMed Web of Science ®Google Scholar
• OberlanderTF.GrunauRE.FitzgeraldC.PapsdorfM.RurakD.RiggsW.Pain reactivity in 2-month-old infants after prenatal and postnatal serotonin reuptake inhibitor medication exposure.Pediatrics.200511541142515687451
   PubMed Web of Science ®Google Scholar
• OberlanderTF.PapsdorfM.BrainUM.MisriS.RossC.GrunauRE.Prenatal effects of selective serotonin reuptake inhibitor antidepressants, serotonin transporter promoter genotype (SLC6A4), and maternal mood on child behavior at 3 years of age.Arch Pediatr Adolesc Med.201016444445120439795
   PubMed Web of Science ®Google Scholar
• CroenLA.GretherJK.YoshidaCK.OdouliR.HendrickV.Antidepressant use during pregnancy and childhood autism spectrum disorders.Arch Gen Psychiatry.2011681104111221727247
   PubMed Web of Science ®Google Scholar
• RaiD.LeeBK.DalmanC.GoldingJ.LewisG.MagnussonC.Parental depression, maternal antidepressant use during pregnancy, and risk of autism spectrum disorders: population based case-control study.BMJ.2013346f205923604083
   PubMed Web of Science ®Google Scholar
• JoelsM.BaramTZ.The neuro-symphony of stress.Nat Rev Neurosci.20091045946619339973
   PubMed Web of Science ®Google Scholar
• HolmesA.Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease.Neurosci Biobehav Rev.2008321293131418439676
   PubMed Web of Science ®Google Scholar
• AmatJ.BarattaMV.PaulE.BlandST.WatkinsLR.MaierSF.Medial prefrontal cortex determines how stressor controllability affects behavior and dorsal raphe nucleus.Nat Neurosci.2005836537115696163
   PubMed Web of Science ®Google Scholar
• AmatJ.PaulE.ZarzaC.WatkinsLR.MaierSF.Previous experience with behavioral control over stress blocks the behavioral and dorsal raphe nucleus activating effects of later uncontrollable stress: role of the ventral medial prefrontal cortex.J Neurosci.200626132641327217182776
   PubMed Web of Science ®Google Scholar
• RozeskeRR.EvansAK.FrankMG.WatkinsLR.LowryCA.MaierSF.Uncontrollable, but not controllable, stress desensitizes 5-HT1A receptors in the dorsal raphe nucleus.J Neurosci.201131141071411521976495
   PubMed Web of Science ®Google Scholar
• PetersDA.Prenatal stress: effect on development of rat brain serotonergic neurons.Pharmacol Biochem Behav.198624137713823725840
   PubMed Web of Science ®Google Scholar
• PetersDA.Both prenatal and postnatal factors contribute to the effects of maternal stress on offspring behavior and central 5-hydroxytryptarnine receptors in the rat.Pharmacol Biochem Behav.1988306696733211976
   PubMed Web of Science ®Google Scholar
• PetersDA.Prenatal stress increases the behavioral response to serotonin agonists and alters open field behavior in the rat.Pharmacol Biochem Behav.1986258738773491370
   PubMed Web of Science ®Google Scholar
• MiyagawaK.TsujiM.FujimoriK.SaitoY.TakedaH.Prenatal stress induces anxiety-like behavior together with the disruption of central serotonin neurons in mice.Neurosci Res.20117011111721320553
   PubMed Web of Science ®Google Scholar
• SlotkinTA.BarnesGA.McCookEC.SeidlerFJ.Programming of brainstem serotonin transporter development by prenatal glucocorticoids.Brain Res Dev Brain Res.199693155161
   PubMedGoogle Scholar
• SlotkinTA.KreiderML.TateCA.SeidlerFJ.Critical prenatal and postnatal periods for persistent effects of dexamethasone on serotonergic and dopaminergic systems.Neuropsychopharmacology.20063190491116160705
   PubMed Web of Science ®Google Scholar
• Lerch-HanerJK.FriersonD.CrawfordLK.BeckSG.DenerisES.Serotonergic transcriptional programming determines maternal behavior and offspring survival.Nat Neurosci.2008111001100319160496
   PubMed Web of Science ®Google Scholar
• FranklinTB.RussigH.WeissIC.et alEpigenetic transmission of the impact of early stress across generations.Biol Psychiatry.20106840841520673872
   PubMed Web of Science ®Google Scholar
• HellstromIC.DhirSK.DiorioJC.MeaneyMJ.Maternal licking regulates hippocampal glucocorticoid receptor transcription through a thyroid hormone-serotonin-NGFI-A signalling cascade.Philos Trans R Soc Lond B Biol Sci.20123672495251022826348
   PubMed Web of Science ®Google Scholar
• MeaneyMJ.SzyfM.Maternal care as a model for experience-dependent chromatin plasticity?Trends Neurosci.20052845646316054244
   PubMed Web of Science ®Google Scholar
• MarquezC.PoirierGL.CorderoMl.et alPeripuberty stress leads to abnormal aggression, altered amygdala and orbitofrontal reactivity and increased prefrontal MAOA gene expression.Transl Psychiatry.20133e21623321813
   PubMed Web of Science ®Google Scholar
• JonesKL.SmithRM.EdwardsKS.GivensB.BeversdorfDQ.Combined effect of maternal serotonin transporter genotype and prenatal stress in modulating offspring social interaction.Int J Dev Neurosci.20102852953620470877
   PubMed Web of Science ®Google Scholar
• CarolaV.FrazzettoG.PascucciT.et alIdentifying molecular substrates in a mouse model of the serotonin transporter x environment risk factor for anxiety and depression.Biol Psychiatry.20076384084617949690
   PubMed Web of Science ®Google Scholar
• Van den HoveD.JakobSB.SchrautKG.et alDifferential effects of prenatal stress in 5-htt deficient mice: towards molecular mechanisms of gene x environment interactions.PLoS One.20116e2271521857948
   PubMed Web of Science ®Google Scholar
• BelayH.BurtonCL.LovicV.MeaneyMJ.SokolowskiM.FlemingAS.Early adversity and serotonin transporter genotype interact with hippocampal glucocorticoid receptor mRNA expression, corticosterone, and behavior in adult male rats.Behav Neurosci.201112515016021463019
   PubMed Web of Science ®Google Scholar
• LeschKP.BengelD.HeilsA.et alAssociation of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region.Science.1996274152715318929413
   PubMed Web of Science ®Google Scholar
• BennettAJ.LeschKP.HeilsA.et alEarly experience and serotonin transporter gene variation interact to influence primate CNS function.Mol Psychiatry.2002711812211803458
   PubMed Web of Science ®Google Scholar
• HeilsA.TeufelA.PetriS.et alAllelic variation of human serotonin transporter gene expression.J Neurochem.199666262126248632190
   PubMed Web of Science ®Google Scholar
• MunafoMR.BrownSM.HaririAR.Serotonin transporter (5-HTTLPR) genotype and amygdala activation: a meta-analysis.Biol Psychiatry.20086385285717949693
   PubMed Web of Science ®Google Scholar
• KobiellaA.ReimoldM.UlshoferDE.et alHow the serotonin transporter 5-HTTLPR polymorphism influences amygdala function: the roles of in vivo serotonin transporter expression and amygdala structure.Transl Psychiatry.20111e3722832611
   PubMed Web of Science ®Google Scholar
• FortierE.NoreauA.LeporeF.et alEarly impact of 5-HTTLPR polymorphism on the neural correlates of sadness.Neurosci Lett.201048526126520851164
   PubMed Web of Science ®Google Scholar
• MuellerA.BrockeB.FriesE.LeschKP.KirschbaumC.The role of the serotonin transporter polymorphism for the endocrine stress response in newborns.Psychoneuroendocrinology.20093528929619647944
   PubMed Web of Science ®Google Scholar
• GotlibIH.JoormannJ.MinorKL.HallmayerJ.HPA axis reactivity: a mechanism underlying the associations among 5-HTTLPR, stress, and depression.Biol Psychiatry.20086384785118005940
   PubMed Web of Science ®Google Scholar
• MillerR.WankerlM.StalderT.KirschbaumC.AlexanderN.The serotonin transporter gene-linked polymorphic region (5-HTTLPR) and cortisol stress reactivity: a meta-analysis.Mol Psychiatry.2012181018102422945032
   PubMed Web of Science ®Google Scholar
• GlatzK.MossnerR.HeilsA.LeschKP.Glucocorticoid-regulated human serotonin transporter (5-HTT) expression is modulated by the 5-HTTgenepromotor-linked polymorphic region.J Neurochem.2003861072107812911615
   PubMed Web of Science ®Google Scholar
• PluessM.VeldersFP.BelskyJ.et alSerotonin transporter polymorphism moderates effects of prenatal maternal anxiety on infant negative emotionality.Biol Psychiatry.20106952052521126730
   PubMed Web of Science ®Google Scholar
• KochanskaG.PhilibertRA.BarryRA.Interplay of genes and early mother-child relationship in the development of self-regulation from toddler to preschool age.J Child Psychol Psychiatry.2009501331133819207629
   PubMed Web of Science ®Google Scholar
• BarryRA.KochanskaG.PhilibertRA.G x E interaction in the organization of attachment: mothers' responsiveness as a moderator of children's genotypes.J Child Psychol Psychiatry.2008491313132019120710
   PubMed Web of Science ®Google Scholar
• Mileva-SeitzV.KennedyJ.AtkinsonL.et alSerotonin transporter allelic variation in mothers predicts maternal sensitivity, behavior and attitudes toward 6-month-old infants.Genes Brain Behav.20111032533321232011
   PubMed Web of Science ®Google Scholar
• KargK.BurmeisterM.SheddenK.SenS.The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: evidence of genetic moderation.Arch Gen Psychiatry.20116844445421199959
   PubMed Web of Science ®Google Scholar
• RischN.HerrellR.LehnerT.et alInteraction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis.JAMA.20093012462247119531786
   PubMed Web of Science ®Google Scholar
• UherR.CaspiA.HoutsR.et alSerotonin transporter gene moderates childhood maltreatment's effects on persistent but not single-episode depression: replications and implications for resolving inconsistent results.J Affect Disord.2011135566521439648
   PubMed Web of Science ®Google Scholar
• BarrCS.NewmanTK.ShannonC.et alRearing condition and rh5-HTTLPR interact to influence limbic-hypothalamic-pituitary-adrenal axis response to stress in infant macaques.Biol Psychiatry.20045573373815039002
   PubMed Web of Science ®Google Scholar
• ChampouxM.BennettA.ShannonC.HigleyJD.LeschKP.SuomiSJ.Serotonin transporter gene polymorphism, differential early rearing, and behavior in rhesus monkey neonates.Mol Psychiatry.200271058106312476320
   PubMed Web of Science ®Google Scholar
• HeimC.BinderEB.Current research trends in early life stress and depression: review of human studies on sensitive periods, gene-environment interactions, and epigenetics.Exp Neurol.201223310211122101006
   PubMed Web of Science ®Google Scholar
• CaspiA.McClayJ.MoffittTE.et alRole of genotype in the cycle of violence in maltreated children.Science.200229785185412161658
   PubMed Web of Science ®Google Scholar
• BuckholtzJW.Meyer-LindenbergA.MAOA and the neurogenetic architecture of human aggression.Trends Neurosci.20083112012918258310
   PubMed Web of Science ®Google Scholar
• GattJM.WilliamsLM.SchofieldPR.et alImpact of the HTR3A gene with early life trauma on emotional brain networks and depressed mood.Depress Anxiety.20102775275920694966
   PubMed Web of Science ®Google Scholar
• GattJM.NemeroffCB.SchofieldPR.et alEarly life stress combined with serotonin 3A receptor and brain-derived neurotrophic factor valine 66 to methionine genotypes impacts emotional brain and arousal correlates of risk for depression.Biol Psychiatry.20106881882420728877
   PubMed Web of Science ®Google Scholar
• NieslerB.FlohrT.NothenMM.et alAssociation between the 5' UTR variant C178T of the serotonin receptor gene HTR3A and bipolar affective disorder.Pharmacogenetics.20011147147511505217
   PubMedGoogle Scholar
• HammerC.CichonS.MuhleisenTW.et alReplication of functional serotonin receptor type 3A and B variants in bipolar affective disorder: a European multicenter study.Transl Psychiatry.20122e10322832903
   PubMed Web of Science ®Google Scholar
• MuellerBR.BaleTL.Sex-specific programming of offspring emotionality after stress early in pregnancy.J Neurosci.2008289055906518768700
   PubMed Web of Science ®Google Scholar
• WeaverIC.D'AlessioAC.BrownSE.et alThe transcription factor nerve growth factor-inducible protein a mediates epigenetic programming: altering epigenetic marks by immediate-early genes.J Neurosci.2007271756176817301183
   PubMed Web of Science ®Google Scholar
• WeaverIC.CervoniN.ChampagneFA.et alEpigenetic programming by maternal behavior.Nat Neurosci.2004784785415220929
   PubMed Web of Science ®Google Scholar
• OberlanderTF.WeinbergJ.PapsdorfM.GrunauR.MisriS.DevlinAM.Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses.Epigenetics.200839710618536531
   PubMed Web of Science ®Google Scholar
• RadtkeKM.RufM.GunterHM.et alTransgenerational impact of intimate partner violence on methylation in the promoter of the glucocorticoid receptor.Transl Psychiatry.20111e2122832523
   PubMed Web of Science ®Google Scholar
• McGowanPO.SasakiA.D'AlessioAC.et alEpigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse.Nat Neurosci.20091234234819234457
   PubMed Web of Science ®Google Scholar
• PerroudN.DayerA.PiguetC.et alChildhood maltreatment and methylation of the glucocorticoid receptor gene NR3C1 in bipolar disorder.Br J Psychiatry. 2013;doi:10.1192/bjp.bp.112.120055.
   Google Scholar
• PerroudN.Paoloni-GiacobinoA.PradaP.et alIncreased methylation of glucocorticoid receptor gene (NR3C1) in adults with a history of childhood maltreatment: a link with the severity and type of trauma.Transl Psychiatry.20111e5922832351
   PubMed Web of Science ®Google Scholar
• PhilibertR.MadanA.AndersenA.CadoretR.PackerH.SandhuH.Serotonin transporter mRNA levels are associated with the methylation of an upstream CpG island.Am J Med Genet B Neuropsychiatr Genet.2007144810110516958039
   PubMedGoogle Scholar
• PhilibertRA.SandhuH.HollenbeckN.GunterT.AdamsW.MadanA.The relationship of 5HTT (SLC6A4) methylation and genotype on mRNA expression and liability to major depression and alcohol dependence in subjects from the Iowa Adoption Studies.Am J Med Genet B Neuropsychiatr Genet.2008147B54354917987668
   PubMed Web of Science ®Google Scholar
• vanIJMH.CaspersK.Bakermans-KranenburgMJ.BeachSR.PhilibertR.Methylation matters: interaction between methylation density and serotonin transporter genotype predicts unresolved loss or trauma.Biol Psychiatry.20106840540720591416
   PubMed Web of Science ®Google Scholar
• OlssonCA.FoleyDL.Parkinson-BatesM.et alProspects for epigenetic research within cohort studies of psychological disorder: a pilot investigation of a peripheral cell marker of epigenetic risk for depression.Biol Psychol.20108315916520018225
   PubMed Web of Science ®Google Scholar
• Ouellet-MorinI.WongCC.DaneseA.et alIncreased serotonin transporter gene (SERT) DNA methylation is associated with bullying victimization and blunted cortisol response to stress in childhood: a longitudinal study of discordant monozygotic twins.Psychol Med.2012111
   Web of Science ®Google Scholar
• BeachSR.BrodyGH.TodorovAA.GunterTD.PhilibertRA.Methylation at 5HTT mediates the impact of child sex abuse on women's antisocial behavior: an examination of the Iowa adoptee sample.Psychosom Med.201173838720947778
   PubMed Web of Science ®Google Scholar
• KinnallyEL.CapitanioJP.LeibelR.et alEpigenetic regulation of serotonin transporter expression and behavior in infant rhesus macaques.Genes Brain Behav.2010957558220398062
   PubMed Web of Science ®Google Scholar
• KinnallyEL.FeinbergC.KimD.et alDNA methylation as a risk factor in the effects of early life stress.Brain Behav immun.2011251548155321600281
   PubMed Web of Science ®Google Scholar
• ShumayE.LoganJ.VolkowND.FowlerJS.Evidence that the methylation state of the monoamine oxidase A (MAOA) gene predicts brain activity of MAO A enzyme in healthy men.Epigenetics.201271151116022948232
   PubMed Web of Science ®Google Scholar
• DomschkeK.TidowN.KuithanH.et alMonoamine oxidase A gene DNA hypomethylation - a risk factor for panic disorder?Int J Neuropsychopharmacol.2012151217122822436428
   PubMed Web of Science ®Google Scholar
• MelasPA.WeiY.WongCC.et alGenetic and epigenetic associations of MAOA and NR3C1 with depression and childhood adversities.Int J Neuropsychopharmacol.2013116
   Web of Science ®Google Scholar
• ZhangH.HermanAl.KranzlerHR.et alArray-based profiling of DNA methylation changes associated with alcohol dependence.Alcohol Clin Exp Res.201337(suppl 1)E108E11522924764
   PubMed Web of Science ®Google Scholar
• BarkerJM.ZhangY.WangF.TaylorJR.ZhangH.Ethanol-induced Htr3a promoter methylation changes in mouse blood and brain.Alcohol Clin Exp Res.201337(suppl 1)E101E10722834954
   PubMedGoogle Scholar
• HenschTK.Critical period plasticity in local cortical circuits.Nat Rev Neurosci.2005687788816261181
   PubMed Web of Science ®Google Scholar
• Maya VetencourtJF.SaleA.ViegiA.et alThe antidepressant fluoxetine restores plasticity in the adult visual cortex.Science.200832038538818420937
   PubMed Web of Science ®Google Scholar
• Maya VetencourtJF.TiraboschiE.SpolidoroM.CastrenE.MaffeiL.Serotonin triggers a transient epigenetic mechanism that reinstates adult visual cortex plasticity in rats.Eur J Neurosci.201133495721156002
   PubMed Web of Science ®Google Scholar
• BaroncelliL.SaleA.ViegiA.et alExperience-dependent reactivation of ocular dominance plasticity in the adult visual cortex.Exp Neurol.201022610010920713044
   PubMed Web of Science ®Google Scholar
• GogollaN.CaroniP.LuthiA.HerryC.Perineuronal nets protect fear memories from erasure.Science.20093251258126119729657
   PubMed Web of Science ®Google Scholar
• KarpovaNN.PickenhagenA.LindholmJ.et alFear erasure in mice requires synergy between antidepressant drugs and extinction training.Science.20113341731173422194582
   PubMed Web of Science ®Google Scholar
• PampallonaS.BolliniP.TibaldiG.KupelnickB.MunizzaC.Combined pharmacotherapy and psychological treatment for depression: a systematic review.Arch Gen Psychiatry.20046171471915237083
   PubMed Web of Science ®Google Scholar
• WeikumWM.OberlanderTF.HenschTK.WerkerJF.Prenatal exposure to antidepressants and depressed maternal mood alter trajectory of infant speech perception.Proc Natl Acad Sci U S A.2012109(suppl 2)172211722723045665
   PubMed Web of Science ®Google Scholar