2,130
Views
3
CrossRef citations to date
0
Altmetric
Original Articles

Low-molecular-weight fucoidan and high-stability fucoxanthin from brown seaweed exert prebiotics and anti-inflammatory activities in Caco-2 cells

, , , &
Article: 32033 | Received 23 Apr 2016, Accepted 20 Jun 2016, Published online: 02 Aug 2016

References

  • Artis D. Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut. Nat Rev Immunol. 2008; 8(6): 411–20.
  • Papadakis KA, Targan SR. Role of cytokines in the pathogenesis of inflammatory bowel disease. Ann Rev Med. 2000; 51: 289–98.
  • Shen L, Weber CR, Raleigh DR, Yu D, Turner JR. Tight junction pore and leak pathways: a dynamic duo. Ann Rev Physiol. 2011; 73: 283.
  • Turner JR. Intestinal mucosal barrier function in health and disease. Nat Rev Immunol. 2009; 9(11): 799–809.
  • Bernet MF, Brassart D, Neeser JR, Servin AL. Adhesion of human bifidobacterial strains to cultured human intestinal epithelial cells and inhibition of enteropathogen-cell interactions. Appl Environ Microbiol. 1993; 59(12): 4121–8. [PubMed Abstract] [PubMed CentralFull Text].
  • Schiffrin EJ, Brassart D, Servin AL, Rochat F, Donnet-Hughes A. Immune modulation of blood leukocytes in humans by lactic acid bacteria: criteria for strain selection. Am J Clin Nutr. 1997; 66(2): 515S–20S. [PubMed Abstract].
  • Kirjavainen PV, Ouwehand AC, Isolauri E, Salminen SJ. The ability of probiotic bacteria to bind to human intestinal mucus. FEMS Microbiol Lett. 1998; 167(2): 185–9.
  • Fooks LJ, Gibson GR. Probiotics as modulators of the gut flora. Br J Nutr. 2002; 88(Suppl 1): S39–49.
  • Gill HS, Rutherfurd KJ, Cross ML, Gopal PK. Enhancement of immunity in the elderly by dietary supplementation with the probiotic Bifidobacterium lactis HN019. Am J Clin Nutr. 2001; 74(6): 833–9. [PubMed Abstract].
  • Liu C, Zhang Z-Y, Dong K, Guo X-K. Adhesion and immunomodulatory effects of Bifidobacterium lactis HN019 on intestinal epithelial cells INT-407. World J Gastroenterol. 2010; 16(18): 2283–90.
  • Kennedy MJ, Sandin RL. Influence of growth conditions on Candida albicans adhesion, hydrophobicity and cell wall ultrastructure. J Med Vet Mycol. 1988; 26(2): 79–92.
  • Kylin H. Zur biochemie der meeresalgen. HoppeSeylers Z Physiol Chem. 1913; 83: 171–97.
  • Park S-B, Chun K-R, Kim J-K, Suk K, Jung Y-M, Lee W-H. The differential effect of high and low molecular weight fucoidans on the severity of collagen-induced arthritis in mice. Phytother Res. 2010; 24(9): 1384–91.
  • Chen M-C, Hsu W-L, Hwang P-A, Chou T-C. Low molecular weight fucoidan inhibits tumor angiogenesis through downregulation of HIF-1/VEGF signaling under hypoxia. Marine Drugs. 2015; 13(7): 4436–51.
  • Hsu H-Y, Lin T-Y, Hwang P-A, Tseng L-M, Chen R-H, Tsao S-M, etal. Fucoidan induces changes in the epithelial to mesenchymal transition and decreases metastasis by enhancing ubiquitin-dependent TGFβ receptor degradation in breast cancer. Carcinogenesis. 2013; 34(4): 874–84.
  • Hsu H-Y, Lin T-Y, Wu Y-C, Tsao S-M, Hwang P-A, Shih Y-W, etal. Fucoidan inhibition of lung cancer in vivo and in vitro: role of the Smurf2-dependent ubiquitin proteasome pathway in TGFβ receptor degradation. Oncotarget. 2014; 5(17): 7870–85.
  • Hwang P-A, Hung Y-L, Phan NN, Hieu B-T-N, Chang P-M, Li K-L. The in vitro and in vivo effects of the low molecular weight fucoidan on the bone osteogenic differentiation properties. Cytotechnology 2015; 1–11. http://dx.doi.org/10.1007/s10616-015-9894-5.
  • Choi J-I, Raghavendran HRB, Sung N-Y, Kim J-H, Chun BS, Ahn DH, etal. Effect of fucoidan on aspirin-induced stomach ulceration in rats. Chem Biol Tnteract. 2010; 183(1): 249–54.
  • Matsumoto S, Nagaoka M, Hara T, Kimura-Takagi I, Mistuyama K, Ueyama S. Fucoidan derived from Cladosiphon okamuranus Tokida ameliorates murine chronic colitis through the down-regulation of interleukin-6 production on colonic epithelial cells. Clin Exp Immunol. 2004; 136(3): 432–9.
  • Raghavendran HR, Srinivasan P, Rekha S. Immunomodulatory activity of fucoidan against aspirin-induced gastric mucosal damage in rats. Int Immunopharmacol. 2011; 11(2): 157–63.
  • Zhang XW, Liu Q, Thorlacius H. Inhibition of selection function and leukocyte rolling protects against dextran sodium sulfate-induced murine colitis. Scand J Gastroenterol. 2001; 36(3): 270–5.
  • Heo SJ, Yoon WJ, Kim KN, Ahn GN, Kang SM, Kang DH, etal. Evaluation of anti-inflammatory effect of fucoxanthin isolated from brown algae in lipopolysaccharide-stimulated RAW 264.7 macrophages. Food Chem Toxicol. 2010; 48(8–9): 2045–51.
  • Tan CP, Hou YH. First evidence for the anti-inflammatory activity of fucoxanthin in high-fat-diet-induced obesity in mice and the antioxidant functions in PC12 cells. Inflammation. 2014; 37(2): 443–50.
  • Haugan K, Karunakaran P, Blatny JM, Valla S. The phenotypes of temperature-sensitive mini-RK2 replicons carrying mutations in the replication control gene trfA are suppressed nonspecifically by intragenic cop mutations. J Bacteriol. 1992; 174(21): 7026–32. [PubMed Abstract] [PubMed CentralFull Text].
  • Vittimberga FJ, McDade TP, Perugini RA, Callery MP. Sodium salicylate inhibits macrophage TNF-alpha production and alters MAPK activation. J Surg Res. 1999; 84(2): 143–9.
  • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods. 1983; 65(1–2): 55–63.
  • Narai A, Arai S, Shimizu M. Rapid decrease in transepithelial electrical resistance of human intestinal Caco-2 cell monolayers by cytotoxic membrane perturbents. Toxicol In Vitro. 1997; 11(4): 347–54.
  • Corr SC, Gahan CGM, Hill C. Impact of selected Lactobacillus and Bifidobacterium species on Listeria monocytogenes infection and the mucosal immune response. FEMS Immunol Med Microbiol. 2007; 50(3): 380–8.
  • El-Soud NHA, Said RN, Mosallam DS, Barakat NAM, Sabry MA. Bifidobacterium lactis in treatment of children with acute diarrhea. A randomized double blind controlled trial. J Med Sci. 2015; 15: 403–7.
  • Cummings JH, Macfarlane GT. Gastrointestinal effects of prebiotics. Br J Nutr. 2002; 87(Suppl 2): S145–51.
  • Kawashima T, Murakami K, Nishimura I, Nakano T, Obata A. A sulfated polysaccharide, fucoidan, enhances the immunomodulatory effects of lactic acid bacteria. Int J Mol Med. 2012; 29(3): 447–53. [PubMed Abstract].
  • Smith AG, O'Doherty JV, Reilly P, Ryan MT, Bahar B, Sweeney T. The effects of laminarin derived from Laminaria digitata on measurements of gut health: selected bacterial populations, intestinal fermentation, mucin gene expression and cytokine gene expression in the pig. Br J Nutr. 2011; 105(5): 669–77.
  • Kaplan H, Hutkins RW. Fermentation of fructooligosaccharides by lactic acid bacteria and bifidobacteria. Appl Environ Microbiol. 2000; 66(6): 2682–4.
  • Zanoni S, Pompei A, Cordisco L, Amaretti A, Rossi M, Matteuzzi D. Growth kinetics on oligo- and polysaccharides and promising features of three antioxidative potential probiotic strains. J Appl Microbiol. 2008; 105(5): 1266–76.
  • Huang HL, Ko CH, Yan YY, Wang CK. Antiadhesion and anti-inflammation effects of noni (Morinda citrifolia) fruit extracts on AGS cells during Helicobacter pylori infection. J Agric Food Chem. 2014; 62(11): 2374–83.
  • Hirotani Y, Ikeda K, Kato R, Myotoku M, Umeda T, Ijiri Y, etal. Protective effects of lactoferrin against intestinal mucosal damage induced by lipopolysaccharide in human intestinal Caco-2 cells. Yakugaku Zasshi. 2008; 128(9): 1363–8.
  • Sachindra NM, Sato E, Maeda H, Hosokawa M, Niwano Y, Kohno M, etal. Radical scavenging and singlet oxygen quenching activity of marine carotenoid fucoxanthin and its metabolites. J Agric Food Chem. 2007; 55(21): 8516–22.
  • Lin WC, Shih PH, Wang W, Wu CH, Hsia SM, Wang HJ, etal. Inhibitory effects of high stability fucoxanthin on palmitic acid-induced lipid accumulation in human adipose-derived stem cells through modulation of long non-coding RNA. Food Funct. 2015; 6(7): 2215–23.
  • Hwang PA, Chien SY, Chan YL, Lu MK, Wu CH, Kong ZL, etal. Inhibition of Lipopolysaccharide (LPS)-induced inflammatory responses by Sargassum hemiphyllum sulfated polysaccharide extract in RAW 264.7 macrophage cells. J Agric Food Chem. 2011; 59(5): 2062–8.
  • Iraha A, Chinen H, Hokama A, Yonashiro T, Kinjo T, Kishimoto K, etal. Fucoidan enhances intestinal barrier function by upregulating the expression of claudin-1. World J Gastroenterol. 2013; 19(33): 5500–7.
  • Saitou M, Furuse M, Sasaki H, Schulzke JD, Fromm M, Takano H, etal. Complex phenotype of mice lacking occludin, a component of tight junction strands. Mol Biol Cell. 2000; 11(12): 4131–42.
  • Furuse M, Fujita K, Hiiragi T, Fujimoto K, Tsukita S. Claudin-1 and- Novel integral membrane proteins localizing at tight junctions with no sequence similarity to occluding. J Cell Biol. 1998; 141(7): 1539–50.
  • Amasheh M, Schlichter S, Amasheh S, Mankertz J, Zeitz M, Fromm M, etal. Quercetin enhances epithelial barrier function and increases claudin-4 expression in Caco-2 cells. J Nutr. 2008; 138(6): 1067–73. [PubMed Abstract].
  • Sokol H, Pigneur B, Watterlot L, Lakhdari O, Bermudez-Humaran LG, Gratadoux JJ, etal. Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proceed Natl Acad Sci USA. 2008; 105(43): 16731–6.
  • Kim KN, Heo SJ, Yoon WJ, Kang SM, Ahn G, Yi TH, etal. Fucoxanthin inhibits the inflammatory response by suppressing the activation of NF-kappaB and MAPKs in lipopolysaccharide-induced RAW 264.7 macrophages. Eur J Pharmacol. 2010; 649(1–3): 369–75.
  • Huang HL, Liu CT, Chou MC, Ko CH, Wang CK. Noni (Morinda citrifolia L.) fruit extracts improve colon microflora and exert anti-inflammatory activities in Caco-2 cells. J Med Food. 2015; 18(6): 663–76.
  • Kim EH, Lee Y, Kim HU. Fibrillin 5 is essential for plastoquinone-9 biosynthesis by binding to solanesyl diphosphate synthases in arabidopsis. Plant Cell. 2015; 27(10): 2956–71. [PubMed Abstract].