6,700
Views
426
CrossRef citations to date
0
Altmetric
Original Research Articles

Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes

, , , , , , , & show all
Article: 18396 | Received 16 Mar 2012, Accepted 21 Mar 2012, Published online: 15 Apr 2012

References

  • Stoorvogel W, Kleijmeer MJ, Geuze HJ, Raposo G. The biogenesis and functions of exosomes. 2002, 3: 321-30. 10.3402/jev.v1i0.18396.
  • Poliakov A, Spilman M, Dokland T, Amling CL, Mobley JA. Structural heterogeneity and protein composition of exosome-like vesicles (prostasomes) in human semen. 2009, 69: 159-167. 10.3402/jev.v1i0.18396.
  • Thery C, Zitvogel L, Amigorena S. Exosomes: composition, biogenesis and function. 2002, 2: 569-610.
  • Fevrier B, Raposo G. Exosomes: endosomal-derived vesicles shipping extracellular messages. 2004, 16: 415-21. 10.3402/jev.v1i0.18396.
  • Ohshima K, Inoue K, Fujiwara A, Hatekeyama K, Kanto K, Watanabe Yet al.Let-7 microRNA family is selectively secreted into the extracellular environment via exosomes in a metastatic gastric cancer cell line. 2010, 5: e13247. 10.3402/jev.v1i0.18396.
  • Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. 2007, 9: 654-9. 10.3402/jev.v1i0.18396.
  • Escola JM, Kleijmeer MJ, Stoorvogel W, Griffith JM, Yoshie O, Geuze H. Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes. 1998, 273: 20121-7. 10.3402/jev.v1i0.18396.
  • Clayton A, Mitchell JP, Court J, Linnane S, Mason MD, Tabi Z. Human tumor-derived exosomes down-modulate NKG2D expression. 2008, 180: 7249-58.
  • Lotvall J, Valadi H. Cell to cell signalling via exosomes through esRNA. 2007, 1: 156-8. 10.3402/jev.v1i0.18396.
  • Pegtel DM, Cosmopoulos K, Thorley-Lawson DA, van Eijndhoven MA, Hopmans ES, Lindenberg JLet al.Functional delivery of viral miRNAs via exosomes. 2010, 107: 6328-33. 10.3402/jev.v1i0.18396.
  • Zhan R, Leng X, Liu X, Wang X, Gong J, Yan Let al.Heat shock protein 70 is secreted from endothelial cells by a non-classical pathway involving exosomes. 2009, 387: 229-33. 10.3402/jev.v1i0.18396.
  • Taylor AR, Robinson MB, Gifondorwa DJ, Tytell M, Milligan CE. Regulation of heat shock protein 70 release in astrocytes: role of signaling kinases. 2007, 67: 1815-29. 10.3402/jev.v1i0.18396.
  • Lancaster GI, Febbraio MA. Exosome-dependent trafficking of HSP70: a novel secretory pathway for cellular stress proteins. 2005, 280: 23349-55. 10.3402/jev.v1i0.18396.
  • Clayton A, Turkes A, Navabi H, Mason MD, Tabi Z. Induction of heat shock proteins in B-cell exosomes. 2005, 118: 3631-8. 10.3402/jev.v1i0.18396.
  • Gupta S, Knowlton AA. HSP60 trafficking in adult cardiac myocytes: role of the exosomal pathway. 2007, 292: H3052-6. 10.3402/jev.v1i0.18396.
  • Gastpar R, Gehrmann M, Bausero MA, Asea A, Gross C, Schroeder JAet al.Heat shock protein 70 surface-positive tumor exosomes stimulate migratory and cytolytic activity of natural killer cells. 2005, 65: 5238-47. 10.3402/jev.v1i0.18396.
  • Eldh M, Ekstrom K, Valadi H, Sjostrand M, Olsson B, Jernas Met al.Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA. 2010, 5: e15353. 10.3402/jev.v1i0.18396.
  • Goligorsky MS, Kuo MC, Patschan D, Verhaar MC. Review article: endothelial progenitor cells in renal disease. 2009, 14: 291-7. 10.3402/jev.v1i0.18396.
  • Sheldon H, Heikamp E, Turley H, Dragovic R, Thomas P, Oon CEet al.New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes. 2010, 116: 2385-94. 10.3402/jev.v1i0.18396.
  • Al-Nedawi K, Szemraj J, Cierniewski CS. Mast cell-derived exosomes activate endothelial cells to secrete plasminogen activator inhibitor type 1. 2005, 25: 1744-9. 10.3402/jev.v1i0.18396.
  • Basile DP. The endothelial cell in ischemic acute kidney injury: implications for acute and chronic function. 2007, 72: 151-6. 10.3402/jev.v1i0.18396.
  • Fagan SC, Hess DC, Hohnadel EJ, Pollock DM, Ergul A. Targets for vascular protection after acute ischemic stroke. 2004, 35: 2220-5. 10.3402/jev.v1i0.18396.
  • Fisher M. Injuries to the vascular endothelium: vascular wall and endothelial dysfunction. 2008, 5Suppl 1S4-11.
  • Ades EW, Candal FJ, Swerlick RA, George VG, Summers S, Bosse DCet al.HMEC-1: establishment of an immortalized human microvascular endothelial cell line. 1992, 99: 683-90. 10.3402/jev.v1i0.18396.
  • Raposo G, Nijman HW, Stoorvogel W, Liejendekker R, Harding CV, Melief CJet al.B lymphocytes secrete antigen-presenting vesicles. 1996, 183: 1161-72. 10.3402/jev.v1i0.18396.
  • Thery C, Amigorena S, Raposo G, Clayton A. Isolation and characterization of exosomes from cell culture supernatants and biological fluids. . 2006; Chapter 3: 3.22.1–3.22.29.
  • Keller A, Nesvizhskii AI, Kolker E, Aebersold R. Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search. 2002, 74: 5383-92. 10.3402/jev.v1i0.18396.
  • Nesvizhskii AI, Keller A, Kolker E, Aebersold R. A statistical model for identifying proteins by tandem mass spectrometry. 2003, 75: 4646-58. 10.3402/jev.v1i0.18396.
  • Huber W, von HA, Sultmann H, Poustka A, Vingron M. Variance stabilization applied to microarray data calibration and to the quantification of differential expression. 2002, 18Suppl 1S96-104. 10.3402/jev.v1i0.18396.
  • Smyth GK. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. 2004, 3: Article 3.
  • Wang X, Seed B. A PCR primer bank for quantitative gene expression analysis. 2003, 31: e154. 10.3402/jev.v1i0.18396.
  • Bauer S, Grossmann S, Vingron M, Robinson PN. Ontologizer 2.0 – a multifunctional tool for GO term enrichment analysis and data exploration. 2008, 24: 1650-1. 10.3402/jev.v1i0.18396.
  • Grossmann S, Bauer S, Robinson PN, Vingron M. Improved detection of overrepresentation of Gene-Ontology annotations with parent child analysis. 2007, 23: 3024-31. 10.3402/jev.v1i0.18396.
  • Slot JW, Geuze HJ. Cryosectioning and immunolabeling. 2007, 2: 2480-91. 10.3402/jev.v1i0.18396.
  • Brodsky SV, Zhang F, Nasjletti A, Goligorsky MS. Endothelium-derived microparticles impair endothelial function in vitro. 2004, 286: H1910-5. 10.3402/jev.v1i0.18396.
  • Mezentsev A, Merks RM, O'Riordan E, Chen J, Mendelev N, Goligorsky MSet al.Endothelial microparticles affect angiogenesis in vitro: role of oxidative stress. 2005, 289: H1106-14. 10.3402/jev.v1i0.18396.
  • Wiese S, Reidegeld KA, Meyer HE, Warscheid B. Protein labeling by iTRAQ: a new tool for quantitative mass spectrometry in proteome research. 2007, 7: 340-50. 10.3402/jev.v1i0.18396.
  • Ross PL, Huang YN, Marchese JN, Williamson B, Parker K, Hattan Set al.Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents. 2004, 3: 1154-69. 10.3402/jev.v1i0.18396.
  • Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W. MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis. 2010, 88: 851-6. 10.3402/jev.v1i0.18396.
  • Simpson RJ, Jensen SS, Lim JW. Proteomic profiling of exosomes: current perspectives. 2008, 8: 4083-99. 10.3402/jev.v1i0.18396.
  • van Niel G, Raposo G, Candalh C, Boussac M, Hershberg R, Cerf-Bensussan Net al.Intestinal epithelial cells secrete exosome-like vesicles. 2001, 121: 337-49. 10.3402/jev.v1i0.18396.
  • Brillard-Bourdet M, Rehault S, Juliano L, Ferrer M, Moreau T, Gauthier F. Amidolytic activity of prostatic acid phosphatase on human semenogelins and semenogelin-derived synthetic substrates. 2002, 269: 390-5. 10.3402/jev.v1i0.18396.
  • Jonsson M, Lundwall A, Linse S, Frohm B, Malm J. Truncated semenogelin I binds zinc and is cleaved by prostate-specific antigen. 2006, 27: 542-7. 10.3402/jev.v1i0.18396.
  • Wang XL, Fu A, Spiro C, Lee HC. Proteomic analysis of vascular endothelial cells-effects of laminar shear stress and high glucose. 2009, 2: 445. 10.3402/jev.v1i0.18396.
  • Cooper JT, Stroka DM, Brostjan C, Palmetshofer A, Bach FH, Ferran C. A20 blocks endothelial cell activation through a NF-kappaB-dependent mechanism. 1996, 271: 18068-73. 10.3402/jev.v1i0.18396.
  • Opipari AW Jr, Boguski MS, Dixit VM. The A20 cDNA induced by tumor necrosis factor alpha encodes a novel type of zinc finger protein. 1990, 265: 14705-8.
  • Sluiter W, Pietersma A, Lamers JM, Koster JF. Leukocyte adhesion molecules on the vascular endothelium: their role in the pathogenesis of cardiovascular disease and the mechanisms underlying their expression. 1993, 22Suppl 4S37-44. 10.3402/jev.v1i0.18396.
  • Peterson DB, Sander T, Kaul S, Wakim BT, Halligan B, Twigger Set al.Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. 2008, 8: 2430-46. 10.3402/jev.v1i0.18396.
  • Gu L, Tseng SC, Rollins BJ. Monocyte chemoattractant protein-1. 1999, 72: 7-29.
  • Gerszten RE, Garcia-Zepeda EA, Lim YC, Yoshida M, Ding HA, Gimbrone Jr MAet al.MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions. 1999, 398: 718-23. 10.3402/jev.v1i0.18396.
  • Kim SH, Han SY, Azam T, Yoon DY, Dinarello CA. Interleukin-32: a cytokine and inducer of TNFalpha. 2005, 22: 131-42.
  • Carlos T, Kovach N, Schwartz B, Rosa M, Newman B, Wayner Eet al.Human monocytes bind to two cytokine-induced adhesive ligands on cultured human endothelial cells: endothelial-leukocyte adhesion molecule-1 and vascular cell adhesion molecule-1. 1991, 77: 2266-71.
  • Curran JE, Weinstein SR, Griffiths LR. Polymorphic variants of NFKB1 and its inhibitory protein NFKBIA, and their involvement in sporadic breast cancer. 2002, 188: 103-7. 10.3402/jev.v1i0.18396.
  • Heyninck K, Kreike MM, Beyaert R. Structure-function analysis of the A20-binding inhibitor of NF-kappa B activation, ABIN-1. 2003, 536: 135-40. 10.3402/jev.v1i0.18396.
  • Ostergaard L, Simonsen U, Eskildsen-Helmond Y, Vorum H, Uldbjerg N, Honore Bet al.Proteomics reveals lowering oxygen alters cytoskeletal and endoplasmatic stress proteins in human endothelial cells. 2009, 9: 4457-67. 10.3402/jev.v1i0.18396.
  • Kovacevic Z, Sivagurunathan S, Mangs H, Chikhani S, Zhang D, Richardson DR. The metastasis suppressor, N-myc downstream regulated gene 1 (NDRG1), upregulates p21 via p53-independent mechanisms. 2011, 32: 732-40. 10.3402/jev.v1i0.18396.
  • De LF, Zhang T, Wauquier C, Huez G, Kruys V, Gueydan C. The cold-inducible RNA-binding protein migrates from the nucleus to cytoplasmic stress granules by a methylation-dependent mechanism and acts as a translational repressor. 2007, 313: 4130-44. 10.3402/jev.v1i0.18396.
  • Zeng Y, Kulkarni P, Inoue T, Getzenberg RH. Down-regulating cold shock protein genes impairs cancer cell survival and enhances chemosensitivity. 2009, 107: 179-88. 10.3402/jev.v1i0.18396.
  • Sowter HM, Ratcliffe PJ, Watson P, Greenberg AH, Harris AL. HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors. 2001, 61: 6669-73.
  • van Balkom BW, Pisitkun T, Verhaar MC, Knepper MA. Exosomes and the kidney: prospects for diagnosis and therapy of renal diseases. 2011, 80: 1138-45. 10.3402/jev.v1i0.18396.
  • Zhou H, Yuen PS, Pisitkun T, Gonzales PA, Yasuda H, Dear JWet al.Collection, storage, preservation, and normalization of human urinary exosomes for biomarker discovery. 2006, 69: 1471-6.
  • Rabinowits G, Gercel-Taylor C, Day JM, Taylor DD, Kloecker GH. Exosomal microRNA: a diagnostic marker for lung cancer. 2009, 10: 42-6. 10.3402/jev.v1i0.18396.
  • Skog J, Wurdinger T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves Met al.Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. 2008, 10: 1470-6. 10.3402/jev.v1i0.18396.
  • Simpson RJ, Lim JW, Moritz RL, Mathivanan S. Exosomes: proteomic insights and diagnostic potential. 2009, 6: 267-83. 10.3402/jev.v1i0.18396.