1,756
Views
86
CrossRef citations to date
0
Altmetric
Short Communications

Tumour-derived exosomes as antigen delivery carriers in dendritic cell-based immunotherapy for malignant mesothelioma

, , , &
Article: 22492 | Received 30 Jul 2013, Accepted 30 Sep 2013, Published online: 24 Oct 2013

References

  • Kesimer M, Scull M, Brighton B, DeMaria G, Burns K, O'Neal W, etal. Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense. FASEB J. 2009; 23: 1858–68.
  • Yang C, Robbins PD. The roles of tumor-derived exosomes in cancer pathogenesis. Clin Dev Immunol. 2011; 2011: 842–9.
  • Van Niel G, Porto-Carreiro I, Simoes S, Raposo G. Exosomes: a common pathway for a specialized function. J Biochem. 2006; 140: 13–21.
  • Schorey J, Bhatnagar S. Exosome function: from tumor immunology to pathogen biology. Traffic. 2008; 9: 871–81.
  • Duijvesz D, Luider T, Bangma CH, Jenster G. Exosomes as biomarker treasure chests for prostate cancer. Eur Urol. 2011; 59: 823–31.
  • Wolfers J, Lozier A, Raposo G, Regnault A, Théry C, Masurier C, etal. Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. Nat Med. 2001; 7: 297–303.
  • André F, Schartz NEC, Chaput N, Flament C, Raposo G, Amigorena S, etal. Tumor-derived exosomes: a new source of tumor rejection antigens. Vaccine. 2002; 20(Suppl 4): A28–31.
  • Clayton A, Mason MD. Exosomes in tumour immunity. Curr Oncol. 2009; 16: 46–9.
  • Lee E-Y, Park K-S, Yoon YJ, Lee J, Moon H-G, Jang SC, etal. Therapeutic effects of autologous tumor-derived nanovesicles on melanoma growth and metastasis. PLoS One. 2012; 7: e33330.
  • Zhang Y, Luo C. Exosomes derived from IL-12-anchored renal cancer cells increase induction of specific antitumor response in vitro: a novel vaccine for renal cell carcinoma. Int J Oncol. 2010; 36: 133–40.
  • Bu N, Wu H, Sun B, Zhang G, Zhan S, Zhang R, etal. Exosome-loaded dendritic cells elicit tumor-specific CD8+ cytotoxic T cells in patients with glioma. J Neurooncol. 2011; 104: 659–67.
  • Andre F, Schartz N, Movassagh M. Malignant effusions and immunogenic tumour-derived exosomes. Lancet. 2002; 360: 295–305.
  • Hegmans JPJJ, Hemmes A, Aerts JG, Hoogsteden HC, Lambrecht BN. Immunotherapy of murine malignant mesothelioma using tumor lysate-pulsed dendritic cells. Am J Respir Crit Care Med. 2005; 171: 1168–77.
  • Hegmans JP, Veltman JD, Lambers ME, De Vries IJM, Figdor CG, Hendriks RW, etal. Consolidative dendritic cell-based immunotherapy elicits cytotoxicity against malignant mesothelioma. Am J Respir Crit Care Med. 2010; 181: 1383–90.
  • Bard MP, Hegmans JP, Hemmes A, Luider TM, Willemsen R, Severijnen L-A, etal. Proteomic analysis of exosomes isolated from human malignant pleural effusions. Am J Respir Cell Mol Biol. 2004; 31: 114–21.
  • Hegmans JPJJ, Bard MPL, Hemmes A, Luider TM, Kleijmeer MJ, Prins J-B, etal. Proteomic analysis of exosomes secreted by human mesothelioma cells. Am J Pathol. 2004; 164: 1807–15.
  • Clayton A, Mitchell JP, Court J, Mason MD, Tabi Z. Human tumor-derived exosomes selectively impair lymphocyte responses to interleukin-2. Cancer Res. 2007; 67: 7458–66.
  • Théry C, Amigorena S. Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Curr Protoc Cell Biol. 2006; 1–29.
  • Lutz MB, Kukutsch N, Ogilvie AL, Rössner S, Koch F, Romani N, etal. An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J Immunol Methods. 1999; 223: 77–92.
  • Liu JP, Hsieh YZ, Wiesler D, Novotny M. Design of 3-(4-carboxybenzoyl)-2-quinolinecarboxaldehyde as a reagent for ultrasensitive determination of primary amines by capillary electrophoresis using laser fluorescence detection. Anal Chem. 1991; 63: 408–12.