1,213
Views
18
CrossRef citations to date
0
Altmetric
Original Articles

Amelioration of lead-induced hepatotoxicity by Allium sativum extracts in Swiss albino mice

, &
Article: 4621 | Received 30 Mar 2009, Published online: 07 Jan 2010

References

  • Courtois E, Marques M, Barrientos A. Lead-induced down-regulation of soluble guanylate cyclase in isolated rat aortic segments mediated by reactive oxygen species and cyclo-oxygenase-2. J Am Soc Nephrol. 2003; 14: 1464–70.
  • Meyer SA, Kulkarni AP. Hepatotoxicity. Introduction to biochemical toxicology. Hodgson E, Smart RCJohn Wiley. New York, 2001; 3: 487–90.
  • Gurer H, Ercal N. Can antioxidants be beneficial in the treatment of lead poisoning?. Free Radic Biol Med. 2000; 29: 927–45.
  • Bechara EJH. Lead poisoning and oxidative stress. Free Radic Biol Med. 2004; 36: S22.
  • Flora SJ, Saxena G, Gautam P, Kaur P, Gill KD. Response of lead-induced oxidative stress and alterations in biogenic amines in different rat brain regions to combined administration of DMSA and MiADMSA. Chem Biol Interact. 2007; 170: 209–20.
  • Flora SJS, Saxena G, Mehta A. Reversal of lead-induced neuronal apoptosis by chelation treatment in rats: role of ROS and intracellular Ca2 + . J Pharmacol Exp Ther. 2007; 322: 108–16.
  • Cory-Slechta DA, Weiss B, Cox C. Mobilization and redistribution of lead over the course of calcium disodium ethylene diamine tetra acetate chelation therapy. J Pharmacol Exp Ther. 1987; 243: 804–13.
  • Ding GS, Liang YY. Antidotal effects of dimercaptosuccinic acid. J Appl Toxicol. 1991; 11: 7–14.
  • Bosque MA, Domingo JL, Corbella J, Jones MM, Singh PK. Developmental toxicity evaluation of monoisoamyl meso-2,3-dimercaptosuccinate in mice. J Toxicol Environ Health. 1994; 42: 443–50.
  • Hassan HA, El-Agmy SM, Gaur RL, Fernando A, Raj MH, Ouhtit A. In vivo evidence of hepato- and reno-protective effect of garlic oil against sodium nitrite-induced oxidative stress. Int J Biol Sci. 2009; 5: 249–55.
  • Plastunov B, Zub S. Lipid peroxidation processes and antioxidant defense under lead intoxication and iodine-deficient in experiment. An Univ Mariae Curie Sklodowska Lublin-polonia. 2008; 21: 215–7.
  • Banerjee SK, Maulik M, Manchanda SC, Dinda AK, Das TK, Maulik SK. Garlic-induced alteration in rat liver and kidney morphology and associated changes in endogenous antioxidant status. Food Chem Toxicol. 2001; 39: 793–7.
  • Nwanjo HU, Ojiako OA. Effect of vitamins E and C on exercise induced oxidative stress. Global J Pure Appl Sci. 2005; 12: 199–202.
  • Marklund S, Marklund G. Involvement of superoxide anion radical in the autooxidation of pyrogallol and convenient assay for SOD. Eur J Biochem. 1974; 47: 469–74.
  • Aebi HE. Catalase. Methods of enzymatic analysis. Bergmeyer HU, Bergmeyer J, Grabl MVelag Chemie Gmbh. Weinheim, 1993; 3: 273–86.
  • Ellman GC. Tissue sulfhydryl groups. Arch Biochem Biophys. 1959; 82: 70–7.
  • Reitman S, Frankel AS. A colorimetric method for the determination of serum glutamic oxaloacetic and glutamic pyruvic transaminase. Am J Clin Pathol. 1957; 28: 53–6.
  • Sadashivam S, Manickam A. Biochemical methods. India. 1996; 2: 121–4.
  • Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurements with the folin phenol reagent. J Biol Chem. 1951; 193: 265–75.
  • Zak B. Cholesterol methodologies: a review. Clin Chem. 1977; 23: 1201–14.
  • Herbert LN. History of lead poisoning in the world. In: Abraham M. George Proceedings of the International Conference on Lead Poisoning, Prevention and Treatment, 8–10 February; 1999. p. 17–25.
  • Osawa T, Kato Y. Protective role of antioxidative food factors in oxidative stress caused by hyperglycemia. Ann NY Acad Sci. 2005; 1043: 440–51.
  • Mohammad IK, Mahdi AA, Raviraja A, Najmul I, Iqbal A, Thuppil V. Oxidative stress in painters exposed to low lead levels. Arh Hig Rada Toksikol. 2008; 59: 161–9.
  • Adanaylo VN, Oteiza PI. Lead intoxication: antioxidant defenses and oxidative damage in rat brain. Toxicology. 1999; 135: 77–85.
  • Ercal N, Gurer-Orhan H, Aykin-Burns N. Toxic metals and oxidative stress. Part 1. Mechanisms involved in metal-induced oxidative damage. Curr Top Med Chem. 2001; 1: 529–39.
  • Halliwell B, Gutteridge JMC. Free radicals in biology and medicine. Clarendon. Oxford, 1989
  • Slater TS. Free radical mechanism in tissue injury. Biochem J. 1985; 222: 1–25.
  • Halliwell B. Mechanisms involved in the generation of free radicals. Pathol Biol. 1996; 44: 6–13.
  • Yiin SJ, Lin TH. Lead-catalyzed peroxidation of essential unsaturated fatty acid. Biol Trace Elem Res. 1995; 50: 167–72.
  • Caylak E, Halifeoiglu I, Aydin S, Telo S, Bulmus O, Celik H. The effects of sulfur-containing compounds on total antioxidant capacity levels of liver, kidney and brain in lead-exposed rats. Turkiye Klinikleri J Med Sci. 2007; 27: 823–8.
  • Ding Y, Gonick HC, Vaziri ND. Lead promotes hydroxyl radical generation and lipid peroxidation in cultured aortic endothelial cells. Am J Hypertens. 2000; 13: 552–5.
  • Winterbourn CC. Superoxide as an intracellular sink. Free Radic Biol Med. 1993; 14: 85–90.
  • Dickinson DA, Moellering DR, Iles KE, Patel RP, Levonen AL, Wigley A, et al.. Cytoprotection against oxidative stress and the regulation of glutathione synthesis. Biol Chem. 2003; 384: 527–37.
  • Gürer H, Ozgünes H, Neal R, Spitz DR, Erçal N. Antioxidant effects of N-acetylcysteine and succimer in red blood cells from lead exposed rats. Toxicology. 1998; 128: 181–9.
  • Adaramoye OA, Osaimoje DO, Akinsanya AM, Nneji CM, Fafunso MA, Ademowo OG. Changes in antioxidant status and biochemical indices after acute administration of artemether, artemether–lumefan-trine and halofantrine in rats. J Compilation Basic Clin Pharmacol Toxicol. 2008; 102: 412–8.
  • Cornelius CE. Biochemical evaluation of hepatic function in dogs. J Am Anim Hosp Assoc. 1979; 15: 25–9.
  • Sharma A, Sharma V, Kansal L. Therapeutic Effects of Allium sativum on lead-induced biochemical changes in soft tissues of Swiss albino mice. Phcog Mag. 2009; 5: 364–71.
  • Raquel ES, Ines AG, Juan LC. Lead effects on structural and functional cellular parameters in human red cells from a prenatal hematopoiesis stage. Biometals. 1997; 10: 331–5.
  • Abraham P, Wilfred G. Lysosomal enzymes in the pathogenesis of carbon tetrachloride induced injury to the testis and the rat. Ind J Pharmacol. 2000; 32: 250–1.
  • Wright PJ, Plummer DT. The use of urinary enzyme measurement to detect renal damage caused by nephritic compounds. Biochem Pharmacol. 1974; 23: 65–73.
  • Brain RI, Kay KO. Kidney phosphatase II: the enzyme in disease. Biochem J. 1927; 21: 1104–8.
  • El-Zayat EM, El-Ymany NA, Kamel ZH. Combined supplementation of zinc and vitamin C as protective agents against lead toxicity in growing male albino rats. 1 liver functions. J Egypt Ger Soc Zool. 1996; 20: 115–39.
  • Shalan MG, Mostafa MS, Hassouna MM, El-Nabi SE, El-Refaie A. Amelioration of lead toxicity on rat liver with vitamin C and silymarin supplements. Toxicology. 2005; 206: 1–15.
  • Simons T. Lead–calcium interactions in cellular lead toxicity. Neurotoxicology. 1993; 14: 77–86.
  • Kasperczyk S, Birkner E, Kasperczyk A, Kasperczyk J. Lipids, lipid peroxidation and 7-ketocholesterol in workers exposed to lead. Hum Exp Toxicol. 2005; 24: 287–95.
  • Bashandy SA. Beneficial effect of combined administration of vitamin C and vitamin E in amelioration of chronic lead hepatotoxicity. Egyp J Hosp Med. 2006; 23: 371–84.
  • Kojima M, Nemoto K, Murai U, Yoshimura N, Ayabe Y, Degawa M. Altered gene expression of hepatic lanosterol 14x-demethylase (CYP51) in lead nitrate-treated rats. Arch Toxicol. 2002; 76: 398–403.
  • El Sokkary GH, Abdel-Rahman GH, Kamel ES. Melatonin protects against lead induced hepatic and renal toxicity in male rats. Toxicology. 2005; 231: 25–33.
  • Foulkes EC. Metals and biological membranes. Toxicology of metals. Chang LCRC. Boca Raton FL, 1996; 133–43.
  • Pereira R, Pereira ML, Ribeiro R, Goncalves F. Wildlife animals as sentinels to human health due to environmental exposure to heavy metals. In: Abstract Book. Proceeding of the 11th annual meeting of Europe Society Environmental Toxicology and Chemistry, Madrid, 6–10 May 2001,Europe: SETAC.
  • Omurtag GZ, Güranlioglu FD, Sehirli O, Arbak S, Uslu B, Gedik N, et al.. Protective effect of aqueous garlic extract against naphthalene-induced oxidative stress in mice. J Pharm Pharmacol. 2005; 57: 623–30.
  • Chung LY. The antioxidant properties of garlic compounds: allyl cysteine, alliin, allicin, and allyl disulfide. J Med Food. 2006; 9: 205–13.
  • Kim KM, Chun SB, Koo MS. Differential regulation of NO availability from macrophages and endothelial cells by the garlic components S-allyl cystiene. Free Radic Biol Med. 2001; 30: 747–56.
  • Saravanan G, Prakash J. Effect of garlic (Allium sativum) on lipid peroxidation in experimental myocardial infarction in rats. J Ethinopharmacol. 2004; 94: 155–8.
  • Fatma MEl, Mokhtar IY, Fatma MER. Ameliorating effect of curcumin on sodium arsenite-induced oxidative damage and lipid peroxidation in different rat organs. Food Chem Toxicol. 2009; 47: 249–54.
  • Kwak MK, Kim SG, Kwak JY, Novak RF, Kim ND. Inhibition of cytochrome P4502E1 expression by organosulfur compounds allylsulfide, allylmercaptan and allylmethyl-sulfide in rats. Biochem Pharmacol. 1993; 47: 531–9.
  • Sodimu O, Joseph PK, Augusti KT. Certain biochemical effects of garlic oil on rats maintained on high fat–high cholesterol diet. Experientia. 1984; 40: 78–80.
  • Tandon SK, Sharma BC, Singh S. Chelation in metal intoxication XXVII: chelating agents containing vicinal thioether groups as antidotes of lead toxicity. Drug Chem Toxicol. 1988; 11: 71–84.
  • Block E. The chemistry of garlic and onions. Sci Am. 1985; 252: 114–9.
  • Amagase H, Petesch BL, Matsuura H, Kasuga S, Itakura Y. Intake of garlic and its bioactive components. J Nutr. 2001; 131: 955–62.
  • Miron T, Rabinkov A, Mirelman D, Miron T, Rabinkov A, Mirelman D, Wilchek M, Weiner L. The mode of action of allicin: its ready permeability through phospholipid membranes may contribute to its biological activity. Biochim Biophys Acta. 2000; 1463: 20–30.
  • Badiei K, Pourjaafar M, Nowrooziasl A. Effect of dried garlic powder Allium sativum on lead content of different tissues following subclinical lead poisoning in goats. Ira J Vet Res. 2005; 6: 10–14.