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Thematic cluster: Focus on autism spectrum disorders

Peptides’ role in autism with emphasis on exorphins

, MD, PhD, , , PhD & , MD, PhD
Article: 18958 | Published online: 24 Aug 2012

References

  • Folstein H, Rutter M. Infantile autism: a genetic study of 21 twin pairs. J Child Psychol Psychiatry. 1975; 113: 297–321.
  • Bailey A, Le Couteur A, Gottesman I, Bolton P, Simonoff E, Yuzda E, et al. Autism as a strongly genetic disorder: evidence from a British twin study. Psychol Med. 1995; 25: 63–77. 10.3402/mehd.v23i0.18958.
  • Garrecht M, Austin DW. The plausibility of a role for mercury in the etiology of autism: a cellular perspective. Toxicol Environ Chem. 2011; 93: 1251–73. 10.3402/mehd.v23i0.18958.
  • Nataf R, Skorupka C, Amet L, Lam A, Springbett A, Lathe R. Porphyrinuria in childhood autistic disorder: implications for environmental toxicity. Toxicol Appl Pharmacol. 2006; 214: 99–108. 10.3402/mehd.v23i0.18958.
  • Yong LJ, Pitkow LJ, Ferguson IN. The neuropatho-genesis of mercury toxicity. Mol Psychiatry. 2002; 7: 540–1. 10.3402/mehd.v23i0.18958.
  • Reichelt KL, Knivsberg AM, Lind G, Nødland M. Probable etiology and possible treatment of childhood autism. Brain Dysfunct. 1991; 4: 308–19.
  • Shattock P, Kennedy A, Rowell F, Berney T. Role of neuropeptides in autism and their relationship with classical neurotransmitters. Brain Dysfunct. 1990; 3: 328–45.
  • Cade RJ, Privette RM, Fregly M, Rowland N, Sun Z, Zele V, et al. Autism and schizophrenia: intestinal disorders. Nutr Neurosci. 2000; 3: 57–72.
  • Shanahan MR, Venturini AJ, Daiss JL, Friedman AE. Peptide diagnostic markers for human disorders. European Patent Application. 2000; EP 0 969 015 A2: 1–44.
  • Kost NV, Sokolov OY, Kurasova OB, Dimitriev AD, Tarakanova JN, Gabaeva MV, et al. Beta-casomorphin-7 in infants on different type of feeding and different levels of psychomotor development. Peptides. 2009; 30: 854–60. 10.3402/mehd.v23i0.18958.
  • Reichelt KL, Knivsberg AM. Can the pathophysiology of autism be explained by the nature of the discovered urine peptides?. Nutr Neurosci. 2003; 6: 19–28. 10.3402/mehd.v23i0.18958.
  • Sacco R, Curatolo P, Manzi B, Militerni R, Bravaccio C, Frolli A, et al. Principal pathogenetic components and biological endophenotypes in autism spectrum disorders. Autism Res. 2010; 3: 237–52. 10.3402/mehd.v23i0.18958.
  • Sponheim E, Myhre AM, Reichelt KL, Aasen OC. Peptidmønstre I urin hos barn med mildere former for autisme. Tidsskr Nor Laegeforen. 2006; 126: 1475–7.
  • Reichelt KL, Hole K, Hamberger A, Sælid G, Edminson PD, Braestrup CB, et al. Biologically active peptide-containing fractions in schizophrenia and childhood autism. Adv Biochem Psychopharmacol. 1981; 28: 627–98.
  • Hole K, Bergslien AA, Jørgensen H, Berge OG, Reichelt KL, Trygstad OE. A peptide containing fraction from schizophrenia which stimulates opiate receptors and inhibits dopamine uptake. Neuroscience. 1979; 4: 1139–47. 10.3402/mehd.v23i0.18958.
  • Sun Z, Cade JR. A peptide found in schizophrenia and autism causes behavioural changes in rats. Autism. 1999; 3: 85–95. 10.3402/mehd.v23i0.18958.
  • Sun Z, Cade RJ, Fregly MJ, Privette RM. Beta-casomorphine induces fos-like immunoreactivity in discrete brain regions relevant to schizophrenia and autism. Autism. 1999; 3: 67–83. 10.3402/mehd.v23i0.18958.
  • Reichelt KL, Ekrem J, Scott H. Gluten, milk proteins and autism: dietary intervention effects on behavior and peptide secretion. J Appl Nutr. 1990; 42: 1–11.
  • Kawashti MI, Amin OH, Rowely NG. Possible immunological disorders in autism. Concomittant autoimmunity and immune tolerance. Egypt J Immunol. 2008; 13: 99–104.
  • Trajkovski V, Petlichkovski A, Efinska-Mladenovska O, Trajkov D, Arsov T, Strzova A, et al. Higher plasma concentrations of food specific antibodies in persons with autistic disorder in comparison to their siblings. Focus on Autism and Other Developmental Disabilities. 2008; 23: 176–86. 10.3402/mehd.v23i0.18958.
  • Voidani A, O'Bryan T, Green JA, McCandless J, Woeller KN, Vojdani AA, et al. Immune response to dietary proteins, Gliadin and Cerebellar Peptides in Children with Autism. Nutritional Neurosci. 2004; 7: 151–61. 10.3402/mehd.v23i0.18958.
  • Panksepp J, Normansell L, Sivily S, Rossi J, Zolovick AJ. Casomorphins reduce separation distress in chickens. Peptides. 1978; 5: 829–31. 10.3402/mehd.v23i0.18958.
  • Svedberg J, De Haas J, Leimanstoll G, Paul F, Teschemacher H. Demonstration of beta-casomorphin immunoreactive materials in vitro digests of bovine milk and in small intestinal contents after bovine milk ingestion in adult humans. Peptides. 1985; 6: 825–31. 10.3402/mehd.v23i0.18958.
  • Chabance B, Marteau P, Rambaud JC, Migliore-Samour D, Boynard M, Perrotin P, et al. Casein peptides release and passage to the blood in humans during digestion of milk and yogurt. Biochimie. 1998; 80: 155–65. 10.3402/mehd.v23i0.18958.
  • Gardner MLG. Absorption of intact proteins and peptides. Physiology of the Gastrointestinal Tract. Johnson LR. Raven Press: New York, 1994; 1795–820.
  • Mahe S, Tome D, Demontier AM, Desjeux JF. Absorption of intact morphiceptin by diisopropylflurophosphate – treated rabbit ileum. Peptides. 1989; 10: 45–52. 10.3402/mehd.v23i0.18958.
  • Bouras M, Huneau JF, Tome D. The inhibition of intestinal dipeptidylaminopeptidase-IV promotes the absorption of enterostatin and des-arginine-enterostain across rat jejunum in vitro. Life Sci. 1996; 59: 2147–55. 10.3402/mehd.v23i0.18958.
  • Kastin AJ, Nissen C, Schally AV, Coy DH. Additional evidence that small amounts of a peptide can cross the blood–brain barrier. Pharmacol Biochem Behav. 1979; 14: 717–9. 10.3402/mehd.v23i0.18958.
  • Ermisch A, Brust P, Kretzchmar R, Buhle HJ. On the blood–brain barrier to peptides (3H) beta-casomorphin-5 uptake by eighteen brain regions in vivo. J Neurochem. 1983; 41: 1229–33. 10.3402/mehd.v23i0.18958.
  • Husby S, Jensenius JC, Cant AJ. Passage of un-degraded dietary antigen into the blood of healthy adults. Scand J Immunol. 1984; 22: 83–92. 10.3402/mehd.v23i0.18958.
  • Seifert J, Ganser R, Brebdel W. Die resorption eines proteolytisches proteins pflanzlichen ursprunge aus dem magen-darm-trakt in das blut und in die lymphe von erwachsenen ratten. Z Gastroenterol. 1979; 17: 1–8.
  • Axelsson I, Jacobsson I, Lindberg T, Benediktsson B. Bovine lactoglobulin in human milk. Acta Paediatr Scand. 1986; 75: 702–7. 10.3402/mehd.v23i0.18958.
  • Troncone F, Scarcello A, Donatiello A, Cannataro P, Tabusco A, Auricchio S. Passage of gliadin into human breast milk. Acat Paediatr Scand. 1987; 76: 453–6. 10.3402/mehd.v23i0.18958.
  • Langer SZ. 25 years since the discovery of presynaptoic receptors: present knowledge and future perspectives. Trends Pharmacol Sci. 1997; 18: 95–9. 10.3402/mehd.v23i0.18958.
  • Hadjivassiliou M, Boscolo S, Davies-Jones GAB, Grünewald RA, Not T, Sanders DS, et al. The humoral response in the pathogenesis of gluten ataxia. Neurology. 2002; 58: 1221–6. 10.3402/mehd.v23i0.18958.
  • Horvath K, Papadimitriou JC, Rabaztyn A, Drachenberg C, Tildon IT. Gastrointestinal abnormalities in children with autistic disorder. J Pediatr. 1999; 135: 559–63. 10.3402/mehd.v23i0.18958.
  • Torrente F, Ashwood P, Day R, Marchado N, Furlano RI, Anthony A, et al. Small intestinal enteropathy with epithelial IgG and complement deposition in children with regressive autism. Mol Psychiatry. 2002; 7: 375–82. 10.3402/mehd.v23i0.18958.
  • Wakefield AJ, Anthony A, Murch SH, Thomson M, Montgomery SM, Davies S, et al. Enerocolitis in children with developmental disorders. Am J Gastroenterol. 2000; 95: 2285–95. 10.3402/mehd.v23i0.18958.
  • Jyonouchi H, Sun S, Itokazu N. Innate immunity associated with inflammatory responses and cytokine production against common dietary proteins in patients with autism spectrum disorder. Neuropsychobiology. 2002; 46: 76–84. 10.3402/mehd.v23i0.18958.
  • Heyman M, Desjeux JF. Cytokine-induced alteration of epithelial barrier to food antigens in disease. Ann NY Acad Sci. 2000; 915: 304–11. 10.3402/mehd.v23i0.18958.
  • D'Eufemia P, Celli M, Finnochiaro R, Pacifico L, Viozzi L, Zaccagnini M, et al. Abnormal intestinal permeability in children with autism. Acta Paediatr. 1996; 85: 1076–9. 10.3402/mehd.v23i0.18958.
  • de Magistris L, Familian V, Pascotto A, Sapone A, From A, Iardino P, et al. Alterations of the intestinal barrier in patients with autism spectrum disorders and their first-degree relatives. J Pediatr Gastroenterol Nutr. 2010; 51: 418–24. 10.3402/mehd.v23i0.18958.
  • Knivsberg A-M, Wiig K, Lind G, Nødland M, Reichelt KL. Dietary intervention in Autistic syndromes. Brain Dysfunction. 1990; 3: 315–27.
  • Lucarelli S, Frediani T, Zingoni AM, Ferruzzi F, Giardini O, Quintieri F, et al. Food allergy and infantile autism. Panminerva Med. 1995; 37: 137–41.
  • Whiteley P, Rodgers J, Savery D, Shattock PA. A gluten-free diet as an intervention for autism and associated spectrum disorders: preliminary findings. Autism. 1999; 3: 45–65. 10.3402/mehd.v23i0.18958.
  • Klaveness J, Bigam J. The GFCF kids diet survey. In: The autism Res Unit. Sunderland Univ, ed. Building bridges. 2002, pp. 77–84.
  • Rimland B. Parent rating of behavioral effects of biomedical interventions. ARI publ. 2003: 34.
  • Kniker WT, Andrews A, Hundley A, Garver C. The possible role of intolerance to milk/dairy and wheat/gluten foods in older children and adults with autism spectrum disorder. The autism Res. Unit, Sunderland Univ, ed. ‘2001: An Autism odyssey’. 2001, pp. 183–91.
  • Brudnak MA, Rimland B, Kerry RE, Dailey M, Taylor R, Stayton B, et al. Enzyme-based therapy for autism spectrum disorders-is it worth another look?. Med Hypothesis. 2002; 58: 422–8. 10.3402/mehd.v23i0.18958.
  • Whiteley P, Haracopos D, Knivsberg A-M, Reichelt KL, Parlar S, Jacobsen J, et al. The Scan Brit randomised, controlled, single-blind study of a gluten- and casein-free dietary intervention for children with autism spectrum disorders. Nutrit Neurosci. 2010; 13(2): 87–100. 10.3402/mehd.v23i0.18958.
  • Pennesi CM, Klein LC. Effectiveness of the gluten free, caseiun free diet for children diagnosed with autism spectrum disorder.Based on parental report. Nutrit. Neurosci. 2012; 15(2): 85–91.
  • Knivsberg A-M. Reichelt KL. Høien T. Nødland M. A randomized, controlled study of dietary intervention in Autistic syndromes. Nutrit. Neurosci. 2002; 5: 251–61. 10.3402/mehd.v23i0.18958.
  • Knivsberg A-M, Reichelt KL, Nødland M, Høien T. Austistic sundromes and diet: a follow-up study. Scand J. Educat. Res. 1995; 39: 223–36. 10.3402/mehd.v23i0.18958.