Advanced search
Publication Cover
Pathobiology of Aging & Age-related Diseases Volume 6, 2016 - Issue 1
Journal homepage
893
Views
12
CrossRef citations to date
0
Altmetric
Editorials

Neuropathological assessment and validation of mouse models for Alzheimer's disease: applying NIA-AA guidelines

C. Dirk KeeneDepartment of PathologyUniversity of Washington, Seattle, WA, USA
,
Martin DarvasDepartment of PathologyUniversity of Washington, Seattle, WA, USA
,
Brian KraemerGeriatrics ResearchEducation and Clinical Center, Veterans Affairs Puget Sound Health Care Systems, Seattle, WA, USA;Division of Gerontology and Geriatrics MedicineDepartment of Medicine, University of Washington, Seattle, WA, USA
,
Denny LiggittDepartment of Comparative MedicineUniversity of Washington, Seattle, WA, USA
,
Christina SigurdsonDepartment of PathologyUniversity of California at San Diego, La Jolla, CA, USA;Scripps Research InstituteLa Jolla, CA, USA
&
Warren LadigesDepartment of PathologyUniversity of Washington, Seattle, WA, USA;Department of Comparative MedicineUniversity of Washington, Seattle, WA, USACorrespondence[email protected]
Article: 32397 | Received 25 May 2016, Accepted 25 May 2016, Published online: 16 Jun 2016

References

  • Serrano-Pozo A, Qian J, Monsell SE, Frosch MP, Betensky RA, Hyman BT. Examination of the clinicopathologic continuum of Alzheimer disease in the autopsy cohort of the National Alzheimer Coordinating Center. J Neuropathol Exp Neurol. 2013; 72(12): 1182–92.
  • Montine TJ, Koroshetz WJ, Babcock D, Dickson DW, Galpern WR, Glymour MM, etal. Recommendations of the Alzheimer's disease-related dementias conference. Neurology. 2014; 83(9): 851–60.
  • Thal DR, Rub U, Orantes M, Braak H. Phases of A beta-deposition in the human brain and its relevance for the development of AD. Neurology. 2002; 58: 1791–800.
  • Braak H, Braak E. Neuropathological staging of Alzheimer-related changes. Acta Neuropathol. 1991; 82: 239–59.
  • Mirra SS, Heyman A, McKeel D, Suma SM, Crain BJ, Brownlee LM, etal. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology. 1991; 41: 479–86.
  • Yang Y, Cudaback E, Jorstad NL, Hemingway JF, Hagan CE, Melief EJ, etal. APOE3, but not APOE4, bone marrow transplantation mitigates behavioral and pathological changes in a mouse model of Alzheimer disease. Am J Pathol. 2013; 183(3): 905–17.
  • Kang JH, Korecka M, Figurski MJ, Toledo JB, Blennow K, Zetterberg H, etal. The Alzheimer's disease neuroimaging initiative 2 biomarker core: a review of progress and plans. Alzheimers Dement. 2015; 11(7): 772–91.
  • Wiley JC, Pettan-Brewer C, Ladiges WC. Phenylbutyric acid reduces amyloid plaques and rescues cognitive behavior in AD transgenic mice. Aging Cell. 2011; 10(3): 418–28.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.