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Original Articles

Atherosclerosis: An Infectious Disease?

Pages 79-90 | Published online: 24 Jun 2015

Suggested Reading

  • Anderson JL et al: Randomized secondary prevention trial of azithromycin in patients with coronary artery disease and serological evidence for Chlamydia pneumoniae infection. The Azithromycin in Coronary Artery Disease: Elimination of Myocardial Infection with Chlamydia (ACADEMIC) Study. Circulation 99:1540, 1999
  • Danesh J, Collins R, Peto R: Chronic infections and coronary heart disease: Is there a link? Lancet 350:430, 1997
  • Epstein SE et al: The role of infection in restenosis and atherosclerosis: Focus on cytomegalovirus. Lancet 348 (Suppl 1):S13, 1996
  • Gupta S et al: Elevated Chlamydia pneumoniae antibodies, cardiovascular events, and azithromycin in male survivors of myocardial infarction. Circulation 96:404, 1997
  • Gurfinkel E et al: Randomized trial of roxithromycin in non-Q wave coronary syndromes: ROXIS pilot study. Lancet 350:404, 1997
  • Mattila KJ et al: Role of infection as a risk factor for atherosclerosis, myocardial infarction, and stroke. Clin Infect Dis 26:719,1998
  • Mayr M et al: Endothelial cytotoxicity mediated by serum antibodies to heat shock proteins of Escherichia coli and Chlamydia pneumoniae: Immune reactions to heat shock proteins as a possible link between infection and atherosclerosis. Circulation 99:1560, 1999
  • Muhlestein JB et al: Infection with Chlamydia pneumoniae accelerates the development of atherosclerosis and treatment with azithromycin prevents it in a rabbit model. Circulation 97:633, 1998
  • Pasceri V et al: Association of virulent Helicobacter pylori strains with ischemic heart disease. Circulation 97:1675, 1998
  • Saikku P et al: Chronic Chlamydia pneumoniae infection as a risk factor for coronary heart disease in the Helsinki Heart Study. Ann Intern Med 116:273, 1992
  • Strachan DP et al: Relation of Helicobacter pylori infection to 13-year mortality and incident ischemic heart disease in the Caerphilly Prospective Heart Disease Study. Circulation 98:1286, 1998
  • Strachan DP et al: Relation of Chlamydia pneumoniae serology to mortality and incidence of ischaemic heart disease over 13 years in the Caerphilly Prospective Heart Disease Study. Br Med J 318:1035, 1999

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