Advanced search
Publication Cover
Hospital Practice Volume 37, 2009 - Issue 1
Submit an article Journal homepage
122
Views
25
CrossRef citations to date
0
Altmetric
Original Articles

Systemic Hypothermia Induced within 10 Hours After Birth Improved Neurological Outcome in Newborns with Hypoxic-Ischemic Encephalopathy

Tongchuan LiDepartment of Pediatrics, Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China
, MD,
Falin XuDepartment of Pediatrics, Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China;Henan Key Laboratory for Neonatal Brain Injury, Zhengzhou, China
, MD, PhD,
Xiuyong ChengDepartment of Pediatrics, Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China;Henan Key Laboratory for Neonatal Brain Injury, Zhengzhou, China
, MD,
Xiaoyan GuoDepartment of Pediatrics, Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China
, MD,
Ling JiDepartment of Pediatrics, Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China
, MD,
Zhan ZhangHenan Key Laboratory for Neonatal Brain Injury, Zhengzhou, China
, MD, PhD,
Xiaoyang WangDepartment of Pediatrics, Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China;Henan Key Laboratory for Neonatal Brain Injury, Zhengzhou, China
, MD, PhD,
Klas BlomgrenDepartment of Pediatrics, The Queen Silvia Children's Hospital, Sweden;Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, University of Gothenburg, Sweden
, MD, PhD,
George Simbruner Padiatrie IV, Department of Pediatrics, Medical University Innsbruck, Innsbruck, Austria
, MD &
Changlian ZhuDepartment of Pediatrics, Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China;Henan Key Laboratory for Neonatal Brain Injury, Zhengzhou, ChinaCorrespondence[email protected]
, MD, PhD show all
Pages 147-152 | Published online: 24 Jun 2015

References

  • Lawn JE, Cousens S, Zupan J; Lancet Neonatal Survival Steering Team. 4 million neonatal deaths: When? Where? Why? Lancet. 2005; 365(9462):891–900.
  • Gluckman PD, Wyatt JS, Azzopardi D, et al. Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial. Lancet. 2005; 365(9460):663–670.
  • Shankaran S, Laptook AR, Ehrenkranz RA, et al. Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy. N Engl J Med. 2005; 353(15): 1574–1584.
  • Eicher DJ, Wagner CL, Katikaneni LP, et al. Moderate hypothermia in neonatal encephalopathy: efficacy outcomes. Pediatr Neurol. 2005; 32(1): 11–17.
  • Azzopardi DV, Strohm B, Edwards AD, et al; TOBY Study Group. Moderate hypothermia to treat perinatal asphyxial encephalopathy. N Engl J Med. 2009; 361 (14): 1349–1358.
  • Jacobs S, Hunt R, Tarnow-Mordi W, Inder T, Davis P. Cooling for newborns with hypoxic ischaemic encephalopathy. Cochrane Database Syst Rev. 2007; (4):CD003311.
  • Gunn AJ, Gunn TR, Gunning MI, Williams CE, Gluckman PD. Neuroprotection with prolonged head cooling started before postisch-emic seizures in fetal sheep. Pediatrics. 1998; 102(5): 1098–1106.
  • Sarnat HB, Sarnat MS. Neonatal encephalopathy following fetal distress. A clinical and electroencephalographic study. Arch Neurol. 1976; 33(1):696–705.
  • Thompson CM, Puterman AS, Linley LL, et al. The value of a scoring system for hypoxic ischaemic encephalopathy in predicting neurodevelopmental outcome. Acta Paediatr. 1997; 86(7): 757–761.
  • Palisano R, Rosenbaum P, Walter S, Russell D, Wood E, Galuppi B. Development and reliability of a system to classify gross motor function in children with cerebral palsy. Dev Med Child Neurol. 1997; 39(4): 214–223.
  • Amess PN, Penrice J, Cady EB, et al. Mild hypothermia after severe transient hypoxia-ischemia reduces the delayed rise in cerebral lactate in the newborn piglet. Pediatr Res. 1997; 41(6):803–808.
  • Azzopardi D, Wyatt JS, Cady EB, et al. Prognosis of newborn infants with hypoxic-ischemic brain injury assessed by phosphorus magnetic resonance spectroscopy. Pediatr Res. 1989; 25(5): 445–451.
  • Zhu C, Kang W, Xu F, et al. Erythropoietin improved neurologic outcomes in newborns with hypoxic-ischemic encephalopathy. Pediatrics. 2009; 124(2):e218–e226.
  • Westin B, Miller JA Jr, Nyberg R, Wedenberg E. Neonatal asphyxia pallida treated with hypothermia alone or with hypothermia and transfusion of oxygenated blood. Surgery. 1959; 45(5):868–879.
  • Gunn AJ, Wyatt JS, Whitelaw A, et al; Cool Cap Study Group. Therapeutic hypothermia changes the prognostic value of clinical evaluation of neonatal encephalopathy. J Pediatr. 2008; 152(1):55–58.
  • Edwards AD, Yue X, Cox P, et al. Apoptosis in the brains of infants suffering intrauterine cerebral injury. Pediatr Res. 1997; 42(5):684–689.
  • Zhu C, Wang X, Cheng X, et al. Post-ischemic hypothermia-induced tissue protection and diminished apoptosis after neonatal cerebral hypoxia-ischemia. Brain Res. 2004; 996(1):67–75.
  • Zhu C, Wang X, Xu F, et al. The influence of age on apoptotic and other mechanisms of cell death after cerebral hypoxia-ischemia. Cell Death Differ. 2005; 12(2): 162–176.
  • Ferriero DM. Neonatal brain injury. N Engl J Med. 2004; 351 (19): 1985–1995.
  • Zhu C, Wang X, Huang Z, et al. Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia- ischemia. Cell Death Differ. 2007; 14(4):775–784.
  • Gunn AJ, Thoresen M. Hypothermic neuroprotection. NeuroRx. 2006; 3(2): 154–169.
  • Shah PS, Ohlsson A, Perlman M. Hypothermia to treat neonatal hypoxic ischemic encephalopathy: systematic review. Arch Pediatr Adolesc Med. 2007; 161 (1):951–958.
  • Thoresen M, Whitelaw A. Cardiovascular changes during mild therapeutic hypothermia and rewarming in infants with hypoxic-ischemic encephalopathy. Pediatrics. 2000; 106(1 pt 1):92–99.
  • Eicher DJ, Wagner CL, Katikaneni LP, et al. Moderate hypothermia in neonatal encephalopathy: safety outcomes. Pediatr Neurol. 2005; 32(1): 18–24.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.