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Postgraduate Medicine Volume 109, 2001 - Issue 3
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Original Articles

Necrobiosis lipoidica

Indolent plaques may signal diabetes

Ysabel M. Bello Dr Bello is wound healing fellow and Dr Phillips is professor of dermatology, Boston University School of Medicine, Robert T. Brodell, MD, coordinator of this series, is professor of internal medicine and clinical professor of dermatopathology in pathology, Northeastern Ohio Universities College of Medicine, Rootstown, and associate clinical professor of dermatology, Case Western Reserve University School of Medicine, Cleveland.
, MD &
Tania J. Phillips Dr Bello is wound healing fellow and Dr Phillips is professor of dermatology, Boston University School of Medicine, Robert T. Brodell, MD, coordinator of this series, is professor of internal medicine and clinical professor of dermatopathology in pathology, Northeastern Ohio Universities College of Medicine, Rootstown, and associate clinical professor of dermatology, Case Western Reserve University School of Medicine, Cleveland.
, MD
Pages 93-94 | Published online: 30 Jun 2015

References

  • Muller SA, Winkelmann RK. Necrobiosis lipoidica diabeticorum: a clinical and pathological investigation of 171 cases. Arch Dermatol 1966; 93(3): 272–81
  • Narva WM, Benoit FL, Ringrose EJ, et al. Necrobiosis lipoidica diabeticorum with apparently normal carbohydrate tolerance. Arch Intern Med 1965; 115: 718–22
  • Lowitt MH, Dover JS. Necrobiosis lipoidica. J Am Acad Dermatol 1991; 25 (5 Pt 1): 735–48
  • Freinkel RK. Diabetes mellitus. In: Freedberg IM, Fitzpatrick TB, Eisen AZ, et al, eds. Fitzpatrick's dermatology in general medicine. 5th ed. New York: McGraw-Hill, 1999: 1972
  • Rhodes EL. Fibrinolytic agents in the treatment of necrobiosis lipoidica. Br J Dermatol 1976; 95(6): 673–4
  • Handfield-Jones S, Jones SK, Peachey RD. Nicotinamide treatment in diabetes. Br J Dermatol 1987; 116(2): 277
  • Littler CM, Tschen EH. Pentoxifylline for necrobiosis lipoidica diabeticorum. J Am Acad Dermatol 1987; 17(2 Pt l): 314–6
  • Statham B, Finlay AY, Marks R. A randomized double blind comparison of an aspirin dipyridamole combination versus a placebo in the treatment of necrobiosis lipoidica. Acta Derm Venereol 1981; 61(3): 270–1
  • Bonnetblanc JM, Julia A, Rigaud M. Antithrombotic agents in necrobiosis lipoidica. Acta Derm Venereol 1986; 66(1): 90
  • Heymann WR. Necrobiosis lipoidica treated with topical tretinoin. Cutis 1996; 58(1): 53–4
  • Darvay A, Acland KM, Russell-Jones R. Persistent ulcerated necrobiosis lipoidica responding to treatment with cyclosporin. Br J Dermatol 1999; 141(4): 725–7
  • Marr TJ, Traisman HS, Griffith BH, et al. Necrobiosis lipoidica diabeticorum in a juvenile diabetic: treatment by excision and skin grafting. Cutis 1977; 19(3): 348–50

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