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Practice Pearl

ACCOMPLISH Trial Findings: Combination Benazepril-Amlodipine or Hydrochlorothiazide is Effective for Treating Hypertension

, MD
Pages 199-201 | Published online: 13 Mar 2015

References

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  • . Dahlöf B, Sever PS, Poulter NR,; ASCOT investigators. Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomized controlled trial. Lancet. 2005;366(9489):895–906
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  • . ; ONTARGET InvestigatorsYusuf S, Teo KK, Pogue J,. Telmisartan, ramipril, or both in patients at high risk for vascular events. N Engl J Med. 2008;358(15):1547–1559
  • . Weder AB. The Avoiding Cardiovascular events through COMbination therapy in Patients Living with Systolic Hypertension (ACCOMPLISH) trial: a comparison of first-line combination therapies. Expert Opin in Pharmacother. 2005;6(2):275–281

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