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Postgraduate Medicine Volume 122, 2010 - Issue 6
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Practice Pearl

Review of the ESPRIT Study: Aspirin plus Dipyridamole versus Aspirin Alone for Prevention of Vascular Events after a Noncardioembolic, Mild-to-Moderate Ischemic Stroke or Transient Ischemic Attack

Halina White Department of Neurology and Neurosciences, New York Presbyterian Hospital, Weill Medical College of Cornell, New York, NYCorrespondence[email protected]
, MD &
Dara G. Jamieson Department of Neurology and Neurosciences, New York Presbyterian Hospital, Weill Medical College of Cornell, New York, NY
, MD
Pages 227-229 | Published online: 13 Mar 2015

References

  • . Diener HC, Cunha L, Forbes C, Silvenius J, Smets P, Lowenthal A. European Stroke Prevention Study. 2. Dipyridamole and acetylsalicylic acid in the secondary prevention of stroke. J Neurol Sci. 1996;143(1–2):1–13
  • . CAPRIE Steering Commitee. A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischemic events (CAPRIE). Lancet. 1996;348(9038):1329–1339
  • . Diener HC, Bogousslavsky J, Brass LM, ; MATCH Investigators. Aspirin and clopidogrel compared with clopidogrel alone after recent ischemic stroke or transient ischemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial. Lancet. 2004;364(9431):331–337
  • . Bhatt DL, Fox KA, Hacke W, ; CHARISMA Investigators. Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events. New Engl J Med. 2006;354(16):1706–1717
  • . Sacco RL, Diener HC, Yusuf S, ; PRoFESS Study Group. Aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke. N Engl J Med. 2008;359(12):1238–1251
  • . Mohr JP, Thompson JL, Lazar RM, ; Warfarin-Aspirin Recurrent Stroke Study Group. A comparison of warfarin and aspirin for the prevention of recurrent ischemic stroke. N Engl J Med. 2001;345(20):1444–1451
  • . The Stroke Prevention in Reversible Ischemia Trial (SPIRIT) Study Group. A randomized trial of anticoagulants versus aspirin after cerebral ischemia of presumed arterial origin. Ann Neurol. 1997;42(6):857–865
  • . Chimowitz MI, Lynn MJ, Howlett-Smith H, ; Warfarin-Aspirin Symptomatic Intracranial Disease Trial Investigators. Comparison of warfarin and aspirin for symptomatic intracranial stenosis. N Engl J Med. 2005;352(13):1305–1316
  • . Halkes PH, van Gijn J, Kappelle LJ, Koudstaal PJ, Algra A; ESPRIT Study Group. Medium intensity oral anticoagulants versus aspirin after cerebral ischaemia of arterial origin (ESPRIT): a randomised controlled trial. Lancet Neurol. 2007;6(2):115–124

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