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Clinical Features

Tumor Lysis Syndrome: A Systematic Review of Case Series and Case Reports

, MD, , MD, , MD, , MD, , MD, , MD & , MD, FACP, FCCP, FCCM show all
Pages 92-101 | Published online: 13 Mar 2015

References

  • . Bhuyan C, Saikia BJ, Choudhury N. Oncological emergencies—management guidelines for clinicians. J Indian Med Assoc. 2005; 103(9):474–478
  • . Chasty RC, Liu—Yin JA. Acute tumour lysis syndrome. Br J Hosp Med. 1993;49(7):488–492
  • . Sallan S. Management of acute tumor lysis syndrome. Semin Oncol. 2001;28(2 suppl 5):9–12
  • . Coiffier B, Altman A, Pui CH, Younes A, Cairo MS. Guidelines for the management of pediatric and adult tumor lysis syndrome: an evidence-based review. J Clin Oncol. 2008;26(16):2767–2778
  • . Flombaum CD. Metabolic emergencies in the cancer patient. Semin Oncol. 2000;27(3):322–334
  • . Arrambide K, Toto RD. Tumor lysis syndrome. Semin Nephrol. 1993;13(3):273–280
  • . Ettinger DS, Harker WG, Gerry HW, Sanders RC, Saral R. Hyper-phosphatemia, hypocalcemia, and transient renal failure. Results of cytotoxic treatment of acute lymphoblastic leukemia. JAMA. 1978;239(23):2472–2474
  • . Doane L. Overview of tumor lysis syndrome. Semin Oncol Nurs. 2002;18(3 suppl 3):2–5
  • . Cui T, Wang C, He H, Shi G, Hu L. A rare case of ovarian Burkitt lymphoma associated tumor lysis syndrome. Eur J Gynaecol Oncol. 2010;31(2):209–210
  • . Suzuki T, Takeuchi M, Saeki H, . Super-acute onset of tumor lysis syndrome accompanied by hypercytokinemia during treatment of Hodgkin's lymphoma with ABVD chemotherapy. Clin Ther. 2010;32(3):527–531
  • . Blanchet GV, Allen HF, Mehrotra SP, Richardson M W. The tumor lysis syndrome in a child with multicentric Castleman disease. J Pediatr Hematol Oncol. 2010;32(3):247–249
  • . Godoy H, Kesterson JP, Lele S. Tumor lysis syndrome associated with carboplatin and paclitaxel in a woman with recurrent endometrial cancer. Int J Gynaecol Obstet. 2010;109(3):254
  • . Moreau E, Andre N, Coze C, Padovani L, Mercier C, Ciccolini J. Can CDA deficiency explain tumour lysis syndrome in a child with neuroblastoma receiving gemcitabine? Pediatr Blood Cancer. 2010;54(5):781–782
  • . Kobayashi D, Wofford MM, McLean TW, Lin JJ. Spontaneous tumor lysis syndrome in a child with T-cell acute lymphoblastic leukemia. Pediatr Blood Cancer. 2010;54(5):773–775
  • . Bercovitz RS, Greffe BS, Hunger SP. Acute tumor lysis syndrome in a 7-month-old with hepatoblastoma. Curr Opin Pediatr. 2010; 22(1):113–116
  • . Hsieh PM, Hung KC, Chen YS. Tumor lysis syndrome after transarterial chemoembolization of hepatocellular carcinoma: case reports and literature review. World J Gastroenterol. 2009;15:4726–4728
  • . Huang WS, Yang CH. Sorafenib induced tumor lysis syndrome in an advanced hepatocellular carcinoma patient. World J Gastroenterol. 2009;15(35):4464–4466
  • . Lee JH, Kwon KA, Lee S, . Multicentric Castleman disease complicated by tumor lysis syndrome after systemic chemotherapy. Leuk Res. 2010;34:e42–e45
  • . Al—Kali A, Farooq S, Tfayli A. Tumor lysis syndrome after starting treatment with Gleevec in a patient with chronic myelogenous leukemia. J Clin Pharm Ther. 2009;34:607–610
  • . Chong AL, Ngan BY, Weitzman S, Abla O. Anaplastic large cell lymphoma of the ovary in a pediatric patient. J Pediatr Hematol Oncol. 2009;31(9):702–704
  • . Tsao YT, Chen WL, Tsai WC. Steroids for acute spinal cord injury: revealing silent pathology. Lancet. 2009;374(9688):500
  • . Borne E, Serafi R, Piette F, Mortier L. Tumour lysis syndrome induced by corticosteroid in metastatic melanoma presenting with initial hyperkalemia. J Eur Acad Dermatol Venereol. 2009;23:855–856
  • . Nakamura Y, Hori E, Furuta J, . Tumor lysis syndrome after transcatheter arterial infusion of cisplatin and embolization therapy for liver metastases of melanoma. Int J Dermatol. 2009;48(7):763–767
  • . Hirata Y, Yokote T, Kobayashi K, . Syndrome of inappropriate antidiuretic hormone associated with chemotherapy-induced tumor lysis in a patient with peripheral T-cell lymphoma unspecified. Leuk Lymphoma. 2009;50:1226–1269
  • . Francescone SA, Murphy B, Fallon JT, Hammond K, Pinney S. Tumor lysis syndrome occurring after the administration of rituximab for posttransplant lymphoproliferative disorder. Transplant Proc. 2009; 41(5):1946–1948
  • . Froilan Torres C, Castro Carbajo P, Pajares Villarroya R, . Acute spontaneous tumor lysis syndrome in a patient with Crohn's disease taking immunosuppressants. Rev Esp Enferm Dig. 2009; 101(4):288–294
  • . Chen RL, Chuang SS. Transient spontaneous remission after tumor lysis syndrome triggered by a severe pulmonary infection in an adolescent boy with acute lymphoblastic leukemia. J Pediatr Hematol. Oncol 2009;31(1):76–79
  • . Chang H, Shih LY. Imatinib-induced tumor lysis syndrome: report of a case and review of the literature. Chang Gung Med J. 2008; 31(5):510–514
  • . Furtado M, Rule S. Bortezomib-associated tumor lysis syndrome in multiple myeloma. Leuk Lymphoma. 2008;49:2380–2382
  • . Keane C, Henden A, Bird R. Catastrophic tumour lysis syndrome following single dose of imatinib. Eur J Haematol. 2009;82: 244–245
  • . Sinha R, Bose S, Subramaniam R. Tumor lysis under anesthesia in a child. Acta Anaesthesiol Scand. 2009;53(1):131–133
  • . Shenoy C. Acute spontaneous tumor lysis syndrome in a patient with squamous cell carcinoma of the lung. QJM. 2009;102:71–73
  • . Lin CJ, Chen HH, Hsieh RK, Chen YC, Wu CJ. Acute tumor lysis syndrome in a hemodialysis patient with diffuse large B cell lymphoma. Med Oncol. 2009;26:93–95
  • . Noh GY, Choe DH, Kim CH, Lee JC. Fatal tumor lysis syndrome during radiotherapy for non-small-cell lung cancer. J Clin Oncol. 2008;26(36):6005–6006
  • . Shiba H, Ishida Y, Wakiyama S, Sakamoto T, Misawa T, Yanaga K. Acute tumor lysis syndrome after transarterial chemoembolization for hepatocellular carcinoma. Cancer Sci. 2008;99(10):2104–2105
  • . Konuma T, Ooi J, Takahashi S, . Fatal acute tumor lysis syndrome following intrathecal chemotherapy for acute lymphoblastic leukemia with meningeal involvement. Intern Med. 2008;47(22):1987–1988
  • . Yoshimura K, Joh K, Kitamura H, . A case report of glomerulopathy-associated podocytic infolding in a patient with tumor lysis syndrome. Clin Exp Nephrol. 2008;12(6):522–526
  • . McDonnell C, Barlow R, Campisi P, Grant R, Malkin D. Fatal perioperative acute tumour lysis syndrome precipitated by dexamethasone. Anaesthesia. 2008;63:652–655
  • . Krishnan G, D'Silva K, Al—Janadi A. Cetuximab-related tumor lysis syndrome in metastatic colon carcinoma. J Clin Oncol. 2008; 26(14):2406–2408
  • . Calvo—Villas JM, Urcuyo BM, Umpierrez AM, Sicilia F. Acute tumor lysis syndrome during oral fludarabine treatment for chronic lymphocytic leukemia. Role of treatment with rasburicase. Onkologie. 2008;31(4):197–199
  • . Otrock ZK, Hatoum HA, Salem ZM. Acute tumor lysis syndrome after rituximab administration in Burkitt's lymphoma. Intern Emerg Med. 2008;3(2):161–163
  • . Osthaus WA, Linderkamp C, Bünte C, Jüttner B, Sümpelmann R. Tumor lysis associated with dexamethasone use in a child with leukemia. Paediatr Anaesth. 2008;18(3):268–270
  • . Sonmez M, Ovali E, Omay SB. Tumor lysis syndrome during treatment with AMN107 (Nilotinib) in a patient with chronic myelogenous leukemia accelerated phase. J Clin Pharm Ther. 2008;33(1): 91–92
  • . Kalff A, Shortt J, Farr J, . Laboratory tumor lysis syndrome complicating LBH589 therapy in a patient with acute myeloid leukaemia. Haematologica. 2008;93(1):e16–e17
  • . Hentrich M, Schiel X, Scheidt B, Reitmeier M, Hoffmann U, Lutz L. Fatal tumor lysis syndrome after irinotecan/5-FU/folinic acid/bevacizumab-containing therapy in a patient heavily pretreated for metastatic colon cancer. Acta Oncol. 2008;47(1):155–156
  • . Rujirojindakul P, Kayasut K, Rohitoprakarn M, Lekhakula A. A unique case of transient spontaneous regression complicated with tumor lysis syndrome of T-cell lymphoblastic lymphoma in HIV-infected patient without antiretroviral therapy. J Med Assoc Thai. 2007;90(9):1930–1933
  • . Lin CJ, Lim KH, Cheng YC, Chen HH, Wu CJ. Tumor lysis syndrome after treatment with gemcitabine for metastatic transitional cell carcinoma. Med Oncol. 2007;24:455–457
  • . Lin CJ, Hsieh RK, Lim KH, Chen HH, Cheng YC, Wu CJ. Fatal spontaneous tumor lysis syndrome in a patient with metastatic, androgen-independent prostate cancer. South Med J. 2007;100(9):916–917
  • . Chan JK, Lin SS, McMeekin DS, Berman ML. Patients with malignancy requiring urgent therapy: CASE 3. Tumor lysis syndrome associated with chemotherapy in ovarian cancer. J Clin Oncol. 2005;23:6794–6795
  • . Kurt M, Onal IK, Elkiran T, Altun B, Altundag K, Gullu I. Acute tumor lysis syndrome triggered by zoledronic acid in a patient with metastatic lung adenocarcinoma. Med Oncol. 2005;22:203–206
  • . Kaito E, Terae S, Kobayashi R, Kudo K, Tha KK, Miyasaka K. The role of tumor lysis in reversible posterior leukoencephalopathy syndrome. Pediatr Radiol. 2005;35(7):722–727
  • . Karagiannis A, Tsorlalis I, Kakafika A, Pateinakis P, Perifanis V, Harsoulis F. Acute renal failure due to tumor lysis syndrome in a patient with non-Hodgkin's lymphoma. Ann Hematol. 2005;84:343–346
  • . Oztop I, Demirkan B, Yaren A, . Rapid tumor lysis syndrome in a patient with metastatic colon cancer as a complication of treatment with 5-fuorouracil/leucoverin and irinotecan. Tumori. 2004;90(5): 514–516
  • . Lee KD, Lee K W, Choi IS, . Multicentric Castleman's disease complicated by tumor lysis syndrome. Ann Hematol. 2004;83(11): 722–725
  • . Arnold TM, Reuter J P, Delman BS, Shanholtz CB. Use of single-dose rasburicase in an obese female. Ann Pharmacother. 2004; 38(9):1428–1431
  • . Ralph R, Adrogue HE, Dolson G, Ramanathan V. Acute renal failure due to tumor lysis syndrome in a HIV seropositive patient with Castleman's disease. Nephrol Dial Transplant. 2004;19:1937
  • . Kurt M, Eren OO, Engin H, Güler N. Tumor lysis syndrome following a single dose of capecitabine. Ann Pharmacother. 2004;38:902
  • . Fuente N, Mane JM, Barcelo R, Munoz A, Perez—Hoyos T, Lopez—Vivanco G. Tumor lysis syndrome in a multiple myeloma treated with thalidomide. Ann Oncol. 2004;15(3):537
  • . Busam KJ, Wolchok J, Jungbluth AA, Chapman P. Diffuse melanosis after chemotherapy-induced tumor lysis syndrome in a patient with metastatic melanoma. J Cutan Pathol. 2004;31(3):274–280
  • . Hsu HH, Huang CC. Acute spontaneous tumor lysis in anaplastic large T-cell lymphoma presenting with hyperuricemic acute renal failure. Int J Hematol. 2004;79(1):48–51
  • . Avci Z, Alioglu B, Canan O, . Calcification of the gastric mucosa associated with tumor lysis syndrome in a child with non-Hodgkin lymphoma. J Pediatr Hematol Oncol. 2006;28(5):307–310
  • . McDonnell AM, Lenz KL, Frei—Lahr DA, Hayslip J, Hall PD. Single-dose rasburicase 6 mg in the management of tumor lysis syndrome in adults. Pharmacotherapy. 2006;26(6):806–812
  • . Ajzensztejn D, Hegde VS, Lee SM. Tumor lysis syndrome after treatment with docetaxel for non-small-cell lung cancer. J Clin Oncol. 2006;24:2389–2391
  • . Agnani S, Gupta R, Atray NK, Vachharajani TJ. Marked hyperuricemia with acute renal failure: need to consider occult malignancy and spontaneous tumour lysis syndrome. Int J Clin Pract. 2006; 60(3):364–366
  • . Otrock ZK, Taher AT, Mahfouz RA, Makarem JA, Shamseddine AI. Acute tumor lysis syndrome secondary to hydroxycarbamide in chronic myelomonocytic leukemia. Am J Hematol. 2006;81:220–221
  • . Lee CC, Wu YH, Chung SH, Chen WJ. Acute tumor lysis syndrome after thalidomide therapy in advanced hepatocellular carcinoma. Oncologist. 2006;11:87–88; author reply 9
  • . Tufan A, Unal N, Koca E, Onal I, Aksu S, Haznedaroglu I. Spontaneous tumor lysis syndrome in a patient with diffuse large B cell lymphoma and Richter syndrome. Ann Hematol. 2006;85(3):183–184
  • . Wright JL, Lin DW, Dewan P, Montgomery RB. Tumor lysis syndrome in a patient with metastatic, androgen independent prostate cancer. Int J Urol. 2005;12(11):1012–1013
  • . Chen SW, Hwang WS, Tsao CJ, Liu HS, Huang GC. Hydroxyurea and splenic irradiation-induced tumour lysis syndrome: a case report and review of the literature. J Clin Pharm Ther. 2005;30(6): 623–625
  • . Kopterides P, Lignos M, Mavrou I, Armaganidis A. Steroid-induced tumor lysis syndrome in a patient with mycosis fungoides treated for presumed Pneumocystis carinii pneumonia. Am J Hematol. 2005;80(4):309
  • . Hummel M, Buchheidt D, Reiter S, Bergmann J, Adam K, Hehlmann R. Recurrent chemotherapy-induced tumor lysis syndrome (TLS) with renal failure in a patient with chronic lymphocytic leukemia—successful treatment and prevention of TLS with low-dose rasburicase. Eur J Haematol. 2005;75(6):518–521
  • . Jabr FI. Acute tumor lysis syndrome induced by rituximab in diffuse large B-cell lymphoma. Int J Hematol. 2005;82(4):312–314
  • . Lehner SG, Gould JE, Saad WE, Brown DB. Tumor lysis syndrome after radiofrequency ablation of hepatocellular carcinoma. AJR Am J Roentgenol. 2005;185(5):1307–1309
  • . Ali R, Ozkalemkas F, Ozkan A, . Tumour lysis syndrome with acute renal failure during imatinib therapy. Leuk Res. 2007;31(4): 573–574
  • . Ozkan A, Hakyemez B, Ozkalemkas F, . Tumor lysis syndrome as a contributory factor to the development of reversible posterior leukoencephalopathy. Neuroradiology. 2006;48(12): 887–892
  • . Abe Y, Mizuno K, Horie H, Mizutani K, Okimoto Y. Transient abnormal myelopoiesis complicated by tumor lysis syndrome. Pediatr Int. 2006;48(5):489–492
  • . Kawai K, Takaoka E, Naoi M, . A case of metastatic testicular cancer complicated by tumour lysis syndrome and choriocarcinoma syndrome. Jpn J Clin Oncol. 2006;36(10):665–667
  • . Chanimov M, Koren—Michowitz M, Cohen ML, Pilipodi S, Bahar M. Tumor lysis syndrome induced by dexamethasone. Anesthesiology. 2006;105(3):633–634
  • . McNutt DM, Holdsworth MT, Wong C, Hanrahan JD, Winter SS. Rasburicase for the management of tumor lysis syndrome in neonates. Ann Pharmacother. 2006;40(7–8):1445–1450
  • . Kenealy MK, Prince HM, Honemann D. Tumor lysis syndrome early after treatment with bortezomib for multiple myeloma. Pharmacotherapy. 2006;26:1205–1206; discussion 1206
  • . Yahata T, Nishikawa N, Aoki Y, Tanaka K. Tumor lysis syndrome associated with weekly paclitaxel treatment in a case with ovarian cancer. Gynecol Oncol. 2006;103(2):752–754
  • . Roy—Chaudhury P. Spontaneous self-alkalinization in spontaneous tumor lysis syndrome. Kidney Int. 2006;70(5):824
  • . Saintigny P, Chouahnia K, Cohen R, . Tumor lysis associated with sudden onset of syndrome of inappropriate antidiuretic hormone secretion. Clin Lung Cancer. 2007;8(4):282–284
  • . Khan BA, Deel C, Hellman RN. Tumor lysis syndrome associated with reduced immunosuppression in a lung transplant recipient. Mayo Clin Proc. 2006;81(10):1397–1399
  • . LaRosa C, McMullen L, Bakdash S, . Acute renal failure from xanthine nephropathy during management of acute leukemia. Pediatr Nephrol. 2007;22(1):132–135
  • . Lee MH, Cheng KI, Jang RC, Hsu JH, Dai ZK, Wu JR. Tumour lysis syndrome developing during an operation. Anaesthesia. 2007;62(1): 85–87
  • . Huston A, Brown J, Roodman GD. Tumor lysis syndrome following thalidomide and dexamethasone therapy for newly diagnosed multiple myeloma. Exp Hematol. 2006;34(12):1616
  • . Suh WM, Wainberg ZA, de Vos S, Cohen AH, Kurtz I, Nguyen MK. Acute lymphoblastic leukemia presenting as acute renal failure. Nat Clin Pract Nephrol. 2007;3(2):106–110
  • . Riccio B, Mato A, Olson EM, Berns JS, Luger S. Spontaneous tumor lysis syndrome in acute myeloid leukemia: two cases and a review of the literature. Cancer Biol Ther. 2006;5(12):1614–1617
  • . Sakamoto N, Monzawa S, Nagano H, Nishizaki H, Arai Y, Sugimura K. Acute tumor lysis syndrome caused by transcatheter oily chemoembolization in a patient with a large hepatocellular carcinoma. Cardiovasc Intervent Radiol. 2007;30(3):508–511
  • . Nicholaou T, Wong R, Davis ID. Tumour lysis syndrome in a patient with renal-cell carcinoma treated with sunitinib malate. Lancet. 2007;369(9577):1923–1924
  • . Kiratli PO. Gallium imaging in a patient with tumor lysis syndrome. Clin Nucl Med. 2007;32:578–579
  • . Leibowitz AB, Adamsky C, Gabrilove J, Labow DM. Intraoperative acute tumor lysis syndrome during laparoscopic splenectomy preceded by splenic artery embolization. Surg Laparosc Endosc Percutan Tech. 2007;17(3):210–211
  • . Saylor PJ, Reid TR. Tumor lysis syndrome after treatment of a gastrointestinal stromal tumor with the oral tyrosine kinase inhibitor sunitinib. J Clin Oncol. 2007;25(23):3544–3546
  • . Teo W Y, Loh TF, Tan AM. Avoiding dialysis in tumour lysis syndrome: is urate oxidase effective?—a case report and review of literature. Ann Acad Med Singapore. 2007;36(8):679–683
  • . Chim CS. Rapid complete remission in multiple myeloma with bortezomib/thalidomide/dexamethasone combination therapy following development of tumor lysis syndrome. Cancer Chemother Pharmacol. 2008;62(1):181–182
  • . Akoz AG, Yildirim N, Engin H, . An unusual case of spontaneous acute tumor lysis syndrome associated with acute lymphoblastic leukemia: a case report and review of the literature. Acta Oncol. 2007;46(8):1190–1192
  • . Trobaugh—Lotrario AD, Liang X, Janik JS, Lovell MA, Odom LF. Difficult diagnostic and therapeutic cases: CASE 2. thymoma and tumor lysis syndrome in an adolescent. J Clin Oncol. 2004;22(5): 955–957
  • . Bedrna J PJ. Akuter Harnleiterverschluss nach Bestrahlung chronischer Leukämien mit Röntgenstrahlen. Med Klin. 1929;25:1700–1701
  • . Merrill D. Uremia following x-ray therapy in leukemia. N Engl J Med. 1940;222:94–97
  • . Talbott J. Gout and blood dyscrasias. Medicine. 1959;38(2):173–205
  • . Salkowski E. Beiträge zur Kenntniss der Leukämie. Virchows Arch F Path Anal. 1870;50:174–210
  • . Better OS. History of the crush syndrome: from the earthquakes of Messina, Sicily 1909 to Spitak, Armenia 1988. Am J Nephrol. 1997; 17(3–4):392–394
  • . Lotfi M, Brandwein JM. Spontaneous acute tumor lysis syndrome in acute myeloid leukemia? A single case report with discussion of the literature. Leuk Lymphoma. 1998;29(5–6):625–628
  • . Del Toro G, Morris E, Cairo MS. Tumor lysis syndrome: pathophysiology, definition, and alternative treatment approaches. Clin Adv Hematol Oncol. 2005;3(1):54–61
  • . Wossmann W, Schrappe M, Meyer U, Zimmermann M, Reiter A. Incidence of tumor lysis syndrome in children with advanced stage Burkitt's lymphoma/leukemia before and after introduction of prophylactic use of urate oxidase. Ann Hematol. 2003;82(3):160–165
  • . Linck D, Basara N, Tran V, . Peracute onset of severe tumor lysis syndrome immediately after 4 Gy fractionated TBI as part of reduced intensity preparative regimen in a patient with T-ALL with high tumor burden. Bone Marrow Transplant. 2003;31:935–937
  • . Jeha S. Tumor lysis syndrome. Semin Hematol. 2001;38:4–8
  • . Seftel MD, Bruyere H, Copland M, . Fulminant tumour lysis syndrome in acute myelogenous leukaemia with inv(16)(p13;q22). Eur J Haematol. 2002;69:193–199
  • . Mato AR, Riccio BE, Qin L, . A predictive model for the detection of tumor lysis syndrome during AML induction therapy. Leuk Lymphoma. 2006;47(5):877–883
  • . Montesinos P, Lorenzo I, Martín G, . Tumor lysis syndrome in patients with acute myeloid leukemia: identification of risk factors and development of a predictive model. Haematologica. 2008;93(1):67–74
  • . Annemans L, Moeremans K, Lamotte M, . Incidence, medical resource utilisation and costs of hyperuricemia and tumour lysis syndrome in patients with acute leukaemia and non-Hodg-kin's lymphoma in four European countries. Leuk Lymphoma. 2003;44(1):77–83
  • . Baeksgaard L, Sorensen JB. Acute tumor lysis syndrome in solid tumors—a case report and review of the literature. Cancer Chemother Pharmacol. 2003;51(3):187–192
  • . Gemici C. Tumour lysis syndrome in solid tumours. Clin Oncol (R Coll Radiol). 2006;18:773–780
  • . Mott FE, Esana A, Chakmakjian C, Herrington JD. Tumor lysis syndrome in solid tumors. Support Cancer Ther. 2005;2(3):188–191
  • . Lobe TE, Karkera MS, Custer MD, Shenefelt RE, Douglass EC. Fatal refractory hyperkalemia due to tumor lysis during primary resection for hepatoblastoma. J Pediatr Surg. 1990;25(2):249–250
  • . Ten Harkel AD, Kist—Van Holthe JE, Van Weel M, Van der Vorst MM. Alkalinization and the tumor lysis syndrome. Med Pediatr Oncol. 1998;31(1):27–28
  • . Jones DP, Mahmoud H, Chesney RW. Tumor lysis syndrome: pathogenesis and management. Pediatr Nephrol. 1995;9(2):206–212
  • . Stoves J, Richardson D, Patel H. Tumour lysis syndrome in a patient with metastatic melanoma treated with biochemotherapy. Nephrol Dial Transplant. 2001;16(1):188–189
  • . Malik IA, Vellozo P, Khurshid M, Khan A. Radiation induced tumour lysis syndrome in a patient with leukaemia. J Pak Med Assoc. 1992; 42(8):191–193
  • . Davidson MB, Thakkar S, Hix JK, Bhandarkar ND, Wong A, Schreiber MJ. Pathophysiology, clinical consequences, and treatment of tumor lysis syndrome. Am J Med. 2004;116(8):546–554
  • . Altman A. Acute tumor lysis syndrome. Semin Oncol. 2001;28 (2 suppl 5):3–8
  • . Vaisban E, Braester A, Mosenzon O, Kolin M, Horn Y. Spontaneous tumor lysis syndrome in solid tumors: really a rare condition? Am J Med Sci. 2003;325(1):38–40
  • . Alkhuja S, Ulrich H. Acute renal failure from spontaneous acute tumor lysis syndrome: a case report and review. Ren Fail. 2002;24(2):227–232
  • . Rampello E, Fricia T, Malaguarnera M. The management of tumor lysis syndrome. Nat Clin Pract Oncol. 2006;3(8):438–447
  • . Farley—Hills E, Byrne AJ, Brennan L, Sartori P. Tumour lysis syndrome during anaesthesia. Paediatr Anaesth. 2001;11(2):233–236
  • . Shimada M, Johnson RJ, May WS Jr, . A novel role for uric acid in acute kidney injury associated with tumour lysis syndrome. Nephrol Dial Transplant. 2009;24(10):2960–2964
  • . Koduri PR. Hyperphosphatemia and tumor lysis syndrome. Ann Hematol. 2005;84:696
  • . Hall DJ, Rush JE, Rozanski EA. ECG of the month. Hyperkalemia. J Am Vet Med Assoc. 2010;236(3):299–301
  • . Smith HM, Farrow SJ, Ackerman JD, Stubbs JR, Sprung J. Cardiac arrests associated with hyperkalemia during red blood cell transfusion: a case series. Anesth Analg. 2008;106(4):1062–1069
  • . Clausen T. Hormonal and pharmacological modification of plasma potassium homeostasis. Fundam Clin Pharmacol. 2010;24(5):595–605
  • . Tapiawala S, Badve S V, More N, Shah B V. Severe muscle weakness due to hyperkalemia. J Assoc Physicians India. 2004;52:505–506
  • . Pession A, Masetti R, Gaidano G, . Risk evaluation, prophylaxis, and treatment of tumor lysis syndrome: consensus of an Italian expert panel. Adv Ther. 2011;28(8):684–697
  • . Cairo MS, Coiffier B, Reiter A, Younes A. Recommendations for the evaluation of risk and prophylaxis of tumour lysis syndrome (TLS) in adults and children with malignant diseases: an expert TLS panel consensus. Br J Haematol. 2010;149(4):578–586
  • . Goldman SC, Holcenberg JS, Finklestein JZ, . A randomized comparison between rasburicase and allopurinol in children with lymphoma or leukemia at high risk for tumor lysis. Blood. 2001;97(10):2998–3003
  • . Mughal TI, Ejaz AA, Foringer JR, Coiffier B. An integrated clinical approach for the identification, prevention, and treatment of tumor lysis syndrome. Cancer Treat Rev. 2010;36(2):164–176
  • . Razis E, Arlin ZA, Ahmed T, . Incidence and treatment of tumor lysis syndrome in patients with acute leukemia. Acta Haematol. 1994;91(4):171–174
  • . Lorigan PC, Woodings PL, Morgenstern GR, Scarffe JH. Tumour lysis syndrome, case report and review of the literature. Ann Oncol. 1996;7(6):631–636
  • . Kenny JE, Goldfarb DS. Update on the pathophysiology and management of uric acid renal stones. Curr Rheumatol Rep. 2010; 12(2):125–129
  • . Hande KR, Garrow GC. Acute tumor lysis syndrome in patients with high-grade non-Hodgkin's lymphoma. Am J Med. 1993;94(2):133–139
  • . Conger JD, Falk SA. Intrarenal dynamics in the pathogenesis and prevention of acute urate nephropathy. J Clin Invest. 1977;59(5):786–793
  • . Hande KR, Hixson C V, Chabner BA. Postchemotherapy purine excretion in lymphoma patients receiving allopurinol. Cancer Res. 1981;41(6):2273–2279
  • . Andreoli S P, Clark JH, McGuire WA, Bergstein JM. Purine excretion during tumor lysis in children with acute lymphocytic leukemia receiving allopurinol: relationship to acute renal failure. J Pediatr. 1986;109(2):292–298
  • . Band PR, Silverberg DS, Henderson J F, . Xanthine nephropathy in a patient with lymphosarcoma treated with allopurinol. N Engl J Med. 1970;283(7):354–357
  • . Potter JL, Silvidi AA. Xanthine lithiasis, nephrocalcinosis, and renal failure in a leukemia patient treated with allopurinol. Clin Chem. 1987;33(12):2314–2316
  • . Smalley RV, Guaspari A, Haase—Statz S, Anderson SA, Cederberg D, Hohneker JA. Allopurinol: intravenous use for prevention and treatment of hyperuricemia. J Clin Oncol. 2000;18(8):1758–1763
  • . Hochberg J, Cairo MS. Tumor lysis syndrome: current perspective. Haematologica. 2008;93:9–13
  • . Bertrand Y. Recommendations of the French Society for the Control of Cancers and Leukemias in Children for the treatment of tumor lysis syndrome: results of a pediatric survey [in French]. Arch Pediatr. 2005;12(spec no 1):13–15
  • . Pui CH, Mahmoud HH, Wiley JM, . Recombinant urate oxidase for the prophylaxis or treatment of hyperuricemia in patients with leukemia or lymphoma. J Clin Oncol. 2001;19(3):697–704
  • . Coiffier B, Mounier N, Bologna S, . Efficacy and safety of rasburicase (recombinant urate oxidase) for the prevention and treatment of hyperuricemia during induction chemotherapy of aggressive non-Hodgkin's lymphoma: results of the GRAAL1 (Groupe d'Etude des Lymphomes de l'Adulte Trial on Rasburicase Activity in Adult Lymphoma) study. J Clin Oncol. 2003;21(23):4402–4406
  • . Bosly A, Sonet A, Pinkerton CR, . Rasburicase (recombinant urate oxidase) for the management of hyperuricemia in patients with cancer: report of an international compassionate use study. Cancer. 2003;98(5):1048–1054
  • . Kikuchi A, Kigasawa H, Tsurusawa M, . A study of rasburicase for the management of hyperuricemia in pediatric patients with newly diagnosed hematologic malignancies at high risk for tumor lysis syndrome. Int J Hematol. 2009;90(4):492–500
  • . Cheuk DK, Chiang AK, Chan GC, Ha SY. Urate oxidase for the prevention and treatment of tumor lysis syndrome in children with cancer. Cochrane Database Syst Rev. 2010;6:CD006945
  • . Cairo MS, Bishop M. Tumour lysis syndrome: new therapeutic strategies and classification. Br J Haematol. 2004;127(1):3–11
  • . Bowman W P, Shuster JJ, Cook B, . Improved survival for children with B-cell acute lymphoblastic leukemia and stage IV small noncleaved-cell lymphoma: a pediatric oncology group study. J Clin Oncol. 1996;14:1252–1261
  • . Kjellstrand CM, Cambell DC 2nd, von Hartitzsch B, Buselmeier TJ. Hyperuricemic acute renal failure. Arch Intern Med. 1974;133(3): 349–359

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