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Clinical Focus: Diabetes and Concomitant Disorders

Proactive Cardiovascular Risk Management versus Usual Care in Patients with and without Diabetes Mellitus: CRUCIAL Trial Subanalysis

, MD, , MD, , MD, , MD, , MD & , PhD
Pages 41-53 | Published online: 13 Mar 2015

References

  • . Shaw JE, Sicree RA, Zimmet PZ. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract. 2010;87(1):4–14
  • . Adler AI, Neil HA, Manley SE, Holman RR, Turner RC. Hyperglycemia and hyperinsulinemia at diagnosis of diabetes and their association with subsequent cardiovascular disease in the United Kingdom prospective diabetes study (UKPDS 47). Am Heart J. 1999;138(5 pt 1): S353–S359
  • . Preis SR, Pencina MJ, Hwang SJ, . Trends in cardiovascular disease risk factors in individuals with and without diabetes mellitus in the Framingham Heart Study. Circulation. 2009;120(3):212–220
  • . Skyler JS, Bergenstal R, Bonow RO, ; American Diabetes Association; American College of Cardiology Foundation; American Heart Association. Intensive glycemic control and the prevention of cardiovascular events: implications of the ACCORD, ADVANCE, and VA diabetes trials: a position statement of the American Diabetes Association and a scientific statement of the American College of Cardiology Foundation and the American Heart Association. Circulation. 2009;119(2):351–357
  • . Grundy SM, Benjamin IJ, Burke GL, . Diabetes and cardiovascular disease: a statement for healthcare professionals from the American Heart Association. Circulation. 1999;100(10):1134–1146
  • . Zanella MT, Kohlmann O Jr, Ribeiro AB. Treatment of obesity hypertension and diabetes syndrome. Hypertension. 2001;38(3 pt 2):705–708
  • . Fowler M. Microvascular and macrovascular complications of diabetes. Clin Diabetes. 2008;26(2):77–82
  • . Colhoun HM, Betteridge DJ, Durrington PN, ; CARDS Investigators. Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo-controlled trial. Lancet. 2004;364(9435):685–696
  • . Collins R, Armitage J, Parish S, Sleigh P, Peto R; Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial. Lancet. 2003;361(9374):2005–2016
  • . Sever PS, Poulter NR, Dahlöf B, . Reduction in cardiovascular events with atorvastatin in 2,532 patients with type 2 diabetes: Anglo-Scandinavian Cardiac Outcomes Trial—Lipid-Lowering Arm (ASCOTLLA). Diabetes Care. 2005;28(5):1151–1157
  • . Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. UK Prospective Diabetes Study Group. BMJ. 1998;317(7160):703–713
  • . Gæde P, Lund—Andersen H, Parving HH, Pedersen O. Effect of a multifactorial intervention on mortality in type 2 diabetes. N Engl J Med. 2008;358(6):580–591
  • . Gæde P, Vedel P, Larsen N, Jensen GV, Parving HH, Pedersen O. Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes. N Engl J Med. 2003;348(5):383–393
  • . Neutel JM, Eaddy M, Lunacsek OE, . Predicted coronary heart disease risk reduction and dual blood pressure/cholesterol goal attainment in patients with hypertension treated in real-world clinical practice. J Clin Hypertens. 2010;12(6):396–406
  • . Wong ND, Lopez V, Tang S, Williams GR. Prevalence, treatment, and control of combined hypertension and hypercholesterolemia in the United States. Am J Cardiol. 2006;98(2):204–208
  • . Centers for Disease Control and Prevention. National Health and Nutrition Examination Survey Data, 1999–2006. http://www.cdc.gov/nchs/nhanes/nhanes_questionnaires.htm. Accessed December 14, 2010
  • . Chen L, Mardekian J. Controlling hypertension and dyslipidemia to guideline-recommended levels in persons with diabetes reduces cardiovascular events, and reduces office visits and hospitalizations to non-comorbid levels. Hypertension. 2009;54:e55. Abstract P126
  • . Chobanian AV, Bakris GL, Black HR, ; Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; National Heart, Lung, and Blood Institute; National High Blood Pressure Education Program Coordinating Committee. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension. 2003;42(6):1206–1252
  • . Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). JAMA. 2001;285(19): 2486–2497
  • . Schmittdiel JA, Uratsu CS, Karter AJ, . Why don't diabetes patients achieve recommended risk factor targets? Poor adherence versus lack of treatment intensification. J Gen Intern Med. 2008;23(5): 588–594
  • . Grant RW, Cagliero E, Dubey AK, . Clinical inertia in the management of type 2 diabetes metabolic risk factors. Diabet Med. 2004;21(2):150–155
  • . Greving JP, Denig P, de Zeeuw D, Bilo HJ, Haaijer—Ruskamp FM. Trends in hyperlipidemia and hypertension management in type 2 diabetes patients from 1998–2004: a longitudinal observational study. Cardiovasc Diabetol. 2007;6:25
  • . McKeage K, Siddiqui MA. Amlodipine/atorvastatin fixed-dose combination: a review of its use in the prevention of cardiovascular disease and in the treatment of hypertension and dyslipidemia. Am J Cardiovasc Drugs. 2008;8(1):51–67
  • . Zamorano J, Erdine S, Lopez AP, ; CRUCIAL Investigators. Design and rationale of a real-life study to compare treatment strategies for cardiovascular risk factors: the CRUCIAL study. Postgrad Med. 2010;122(2):7–15
  • . Zamorano J, Erdine S, Pavia A, . Proactive multiple cardiovascular risk factor management compared with usual care in patients with hypertension and additional risk factors: the CRUCIAL trial. Curr Med Res Opin. 2011;27(4):821–833
  • . World Medical Association. (2008) The World Medical Association Declaration of Helsinki. Ethical Principles for Medical Research Involving Human Subjects. Adopted by the 18th World Medical Association General Assembly, Helsinki, Finland, June 1964. Last amended by the World Medical Association General Assembly in Seoul, Korea, October 2008. http://www.wma.net/en/30publications/10policies/b3/. Accessed October 11, 2010
  • . Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med. 1998;15(7):539–553
  • . Wilson PW, D'Agostino RB, Levy D, Belanger AM, Silbershatz H, Kannel WB. Prediction of coronary heart disease using risk factor categories. Circulation. 1998;97(18):1837–1847
  • . Richard Hobbs FD, Gensini G, John Mancini GB, ; JEWEL Study Group. International open-label studies to assess the efficacy and safety of single-pill amlodipine/atorvastatin in attaining blood pressure and lipid targets recommended by country-specific guidelines: the JEWEL programme. Eur J Cardiovasc Prev Rehabil. 2009;16(4):472–480
  • . Flack JM, Victor R, Watson K, . Improved attainment of blood pressure and cholesterol goals using single-pill amlodipine/atorvastatin in African Americans: the CAPABLE trial. Mayo Clin Proc. 2008;83(1):35–45
  • . Jenssen TG, Aguilar—Salinas CA, Hobbs R, . Control of blood pressure and low-density lipoprotein cholesterol with single-pill amlodipine/atorvastatin: a pooled analysis of patients with and without diabetes. Presented at: 44th Annual Meeting of European Association for the Study of Diabetes; September 7–11, 2008; Rome, Italy
  • . Erdine S, Ro YM, Tse HF, . Single-pill amlodipine/atorvastatin helps patients of diverse ethnicity attain recommended goals for blood pressure and lipids (the Gemini-AALA study). J Hum Hypertens. 2009;23(3):196–210
  • . LaSalle J, Hershon K, Berman L, Gibson E, Gillen D, Maroni J. Utility of amlodipine/atorvastatin single-pill therapy in patients with diabetes mellitus: results from the Gemini study. Presented at: 40th Annual Meeting of the European Association for the Study of Diabetes; September 5–9, 2004; Munich, Germany
  • . Aguilar—Salinas CA, Ro YM, Tse HF, . Clinical utility of single-pill amlodipine/atorvastatin for the attainment of blood pressure and lipid goals in patients of diverse ethnicity with diabetes: results from the Gemini AALA study. Presented at: 43rd Annual Meeting of the European Association for the Study of Diabetes; September 18–21, 2007; Amsterdam, The Netherlands
  • . Ferdinand KC, Flack JM, Saunders E, . Amlodipine/atorvastatin single-pill therapy for blood pressure and lipid goals in African Americans: influence of the metabolic syndrome and type 2 diabetes mellitus. J Clin Hypertens (Greenwich). 2009;11(10):585–593
  • . Blank R, LaSalle J, Reeves R, Maroni J, Tarasenko L, Sun F. Single-pill therapy in the treatment of concomitant hypertension and dyslipidemia (the amlodipine/atorvastatin gemini study). J Clin Hypertens. 2005;7(5):264–273
  • . Grundy SM, Cleeman JI, Merz CN, . Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines. Circulation. 2004;110(2):227–239
  • . Sever P, Dahlöf B, Poulter N, ; ASCOT Steering Committee Members. Potential synergy between lipid-lowering and blood-pressure-lowering in the Anglo-Scandinavian Cardiac Outcomes Trial. Eur Heart J. 2006;27(24):2982–2988
  • . Howard BV, Roman MJ, Devereux RB, . Effect of lower targets for blood pressure and LDL cholesterol on atherosclerosis in diabetes: the SANDS randomized trial. JAMA. 2008;299(14):1678–1689

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