86
Views
16
CrossRef citations to date
0
Altmetric
Clinical Focus: Diabetes and Concomitant Disorders

Use of Dipeptidyl Peptidase-4 Inhibitors for the Treatment of Patients with Type 2 Diabetes Mellitus and Chronic Kidney Disease

, MD, MSc
Pages 138-144 | Published online: 13 Mar 2015

References

  • . Ninomiya I, Perkovic V, de Galan BE, ; ADVANCE Collaborative Group. Albuminuria and kidney function independently predict cardiovascular and renal outcomes in diabetes. J Am Soc Nephrol. 2009;20(8):1813–1821
  • . Nathan DM, Buse JB, Davidson MB, ; American Diabetes Association; European Association for Study of Diabetes. Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care. 2009;32(1):193–203
  • . Glucophage (metformin hydrochloride) [package insert]. Princeton, NJ: Bristol-Myers Squibb; 2009
  • . Lubowsky ND, Siegel R, Pittas AG. Management of glycemia in patients with diabetes mellitus and chronic kidney disease. Am J Kid Dis. 2007;50(5):865–879
  • . Holstein A, Plaschke A, Hammer C, Egberts EH. Characteristics and time course of severe glimepiride- versus glibenclamide-induced hypoglycemia. Eur J Pharmocol. 2003;59(2):91–97
  • . Abe M, Okada K, Soma M. Antidiabetic agents in patients with chronic kidney disease and end-stage renal disease on dialysis: metabolism and clinical practice. Curr Drug Metab. 2011;12(1):57–69
  • . Mikhail N. Why should we avoid the use of rosiglitazone? South Med J. 2008;101(3):329–331
  • . Ramirez SP, Albert JM, Blayney MJ, . Rosiglitazone is associated with mortality in chronic hemodialysis patients. J Am Soc Nephrol. 2009;20(5):1094–1101
  • . Byetta (exenatide) [package insert]. San Diego, CA: Amylin Pharmaceuticals; 2009
  • . Victoza (liraglutide) [package insert]. Princeton, NJ: Novo Nordisk; 2010
  • . Mikhail N. Incretin mimetics and dipeptidyl peptidase inhibitors in clinical trials for the treatment of type 2 diabetes. Expert Opin Investig Drugs. 2008;17(6):845–853
  • . Shurraw S, Hemmelgarn B, Lin M, ; Alberta Kidney Disease Network. Association between glycemic control and adverse outcomes in people with diabetes mellitus and chronic kidney disease. Arch Intern Med. 2011;171:1920–1927
  • . Davis TM, Brown SG, Jacobs IG, Bulsara M, Bruce DG, Davis WA. Determinants of severe hypoglycemia complicating type 2 diabetes: the Fremantle diabetes study. J Clin Endocrinol Metab. 2010;95 (5):2240–2247
  • . Scheen AJ. Pharmacokinetics of dipeptidylpeptidase-4 inhibitors. Diabetes Obes Metab. 2010;12(8):648–658
  • . Januvia (sitagliptin) [package insert]. Whitehouse Station, NJ: Merck & Co, Inc; 2011
  • . Januvia [package insert]. European Medicines Agency. http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/000722/WC500039054.pdf. Accessed June 19, 2012
  • . Novartis Pharmaceuticals UK Ltd. Galvus UK. Summary of product characteristics. Camberley. Surrey, UK. January 2011. http://www.medicines.org.uk/emc/medicine/20734/SPC/. Accessed June 19, 2012
  • . Onglyza (saxagliptin) [package insert]. Princeton, NJ: Bristol-Myers Squibb; July 2009
  • . Tradjenta (linagliptin) [package insert]. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc; 2011
  • . Graefe—Mody U, Friedrich C, Port A, . Effect of renal impairment on the pharmacokinetics of the dipeptidyl peptidase-4 inhibitor linagliptin. Diabetes Obes Metab. 2011;13(10):939–946
  • . Lukashevich V, Schweizer A, Shao Q, Groop PH, Kothny W. Safety and efficacy of vildagliptin versus placebo in patients with type 2 diabetes and moderate or severe renal impairment: a randomized placebo-controlled trial. Diabetes Obes Metab. 2011;13(10):947–954
  • . Ito M, Abe M, Okada K, . The dipeptidyl peptidase-4 (DPP-4) inhibitor vildagliptin improves glycemic control in type 2 diabetic patients undergoing hemodialysis. Endocr J. 2011;58(11):979–987
  • . Nowicki M, Rychlik I, Haller H, . Long-term treatment with the dipeptidyl peptidase-4 inhibitor saxagliptin in patients with type 2 diabetes mellitus and renal impairment: a randomised controlled 52-week efficacy and safety study. Int J Clin Pract. 2011;65(12):1230–1239
  • . Chan JC, Scott R, Arjona Ferreira JC, . Safety and efficacy of sitagliptin in patients with type 2 diabetes and chronic renal insufficiency. Diabetes Obes Metab. 2008;10:545–555
  • . Mikhail N. Safety of dipeptidyl peptidase 4 inhibitors for treatment of type 2 diabetes. Curr Drug Saf. 2011;6(5):304–309
  • . Nauck MA, Meininger G, Sheng D, Terranella L, Stein PP; Sitagliptin Study 024 Group. Efficacy and safety of the dipeptidyl peptidase-4 inhibitor, sitagliptin, compared with the sulfonylurea, glipizide, in patients with type 2 diabetes inadequately controlled on metformin alone: a randomized, double-blind, non-inferiority trial. Diabetes Obes Metab. 2007;9(2):194–205
  • . Mikhail N. Combination therapy with DPP-4 inhibitors and pioglitazone in type 2 diabetes: theoretical consideration and therapeutic potential. Vasc Health Risk Manag. 2008;4(6):1–7
  • . Williams—Herman D, Engel SS, Round E, . Safety and tolerability of sitagliptin in clinical studies: a pooled analysis of data from 10,246 patients with type 2 diabetes. BMC Endocr Disord. 2010;10:7
  • . Schweizer A, Dejager S, Foley JE, . Assessing the cardio-cerebrovascular safety of vildagliptin: meta-analysis of adjudicated events from a large phase III type 2 diabetes population. Diabetes Obes Metab. 2010;12(6):485–494
  • . Scirica BM, Bhatt DL, Braunwald E, . The design and rationale of the saxagliptin assessment of vascular outcomes recorded in patients with diabetes mellitus—thrombolysis in myocardial infarction (SAVOR-TIMI) 53 Study. Am Heart J. 2011;162(5):818–825
  • . Jose T, Inzucchi SE. Cardiovascular effects of the DPP-4 inhibitors. Diab Vasc Dis Res. 2012;9(2):109–116
  • . Gooben K, Graber S. Longer-term safety of dipeptidyl peptidase-4 inhibitors in patients with type 2 diabetes mellitus: systematic review and meta-analysis [published online ahead of print April 20, 2012]. Diabetes Obes Metab.
  • . Budde K, Neumayer H, Fritsche L, . The pharmacokinetics of pioglitazone in patients with impaired renal function. Br J Clin Pharmacol. 2003;55(4):368–374
  • . Schneider CA, Ferrannini E, DeFronzo R, . Effect of pioglitazone on cardiovascular outcome in diabetes and chronic kidney disease. J Am Soc Nephrol. 2008;19(1):182–187
  • . Manley HJ, Allock NM. Thiazolidinedione safety and efficacy in ambulatory patients receiving hemodialysis. Pharmacotherapy. 2003;23(7):861–865
  • . Kermani A, Garg A. Thiazolidinedione-associated congestive heart failure and pulmonary edema. Mayo Clin Proc. 2003;78(9): 1088–1091
  • . Azoulay L, Yin H, Filion KB, . The use of pioglitazone and the risk of bladder cancer in people with type 2 diabetes: nested case-control study. BMJ. 2012;344:e3645

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.