The Effects of Methylphenidate on Cognitive Function in Children with Attention–Deficit/Hyperactivity Disorder

References

• . Wolraich M, Brown L, Brown RT, ; Subcommittee on Attention-Deficit/Hyperactivity Disorder; Steering Committee on Quality Improvement and Management. ADHD: clinical practice guideline for the diagnosis, evaluation, and treatment of attention-deficit/hyperactivity disorder in children and adolescents. Pediatrics. 2011;128(5): 1007–1022
   PubMed Web of Science ®Google Scholar
• . American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision. Washington, DC: American Psychiatric Association; 2000
   Google Scholar
• . Polanczyk G, Rhode LA. Epidemiology of attention-deficit/hyperactivity disorder across the lifespan. Curr Opin Psychiatry. 2007;20(4): 386–392
   PubMed Web of Science ®Google Scholar
• . Barkley RA. Attention-deficit/Hyperactivity Disorder: A Handbook for Diagnosis and Treatment. 3rd ed. New York, NY: Guilford Press; 2006
   Google Scholar
• . Castellanos FX, Patti PL, Sharp W, . Developmental trajectories of brain volume abnormalities in children and adolescents with attention-deficit/hyperactivity disorder. JAMA. 2002;288(14):1740–1748
   PubMed Web of Science ®Google Scholar
• . Sonuga–Barke EJ. Causal models of attention-deficit/hyperactivity disorder: from common simple deficits to multiple developmental pathways. Biol Psychiatry. 2005;57(11):1231–1238
   PubMed Web of Science ®Google Scholar
• . Biederman J, Monuteaux MC, Doyle AE, . Impact of executive function deficits and attention-deficit/hyperactivity disorder (ADHD) on academic outcomes in children. J Consult Clin Psychol. 2004;72(5):757–766
   PubMed Web of Science ®Google Scholar
• . Hale JB, Reddy LA, Decker SL, . Development and validation of an attention-deficit/hyperactivity disorder (ADHD) executive function and behavior rating screening battery. J Clin Exp Neuropsychol. 2009;31(8):897–912
   PubMed Web of Science ®Google Scholar
• . Sonuga–Barke EJ, Sergeant JA, Nigg J, Willcutt E. Executive dysfunction and delay aversion in attention deficit hyperactivity disorder: nosologic and diagnostic implications. Child Adolesc Psychiatr Clin N Am. 2008;17(2):367–384, ix
   PubMed Web of Science ®Google Scholar
• . Hale JB, Fiorello CA. School Neuropsychology: A Practitioner's Handbook. New York, NY: Guilford Press; 2004
   Google Scholar
• . Willcutt EG, Doyle AE, Nigg JT, Faraone SV, Pennington BF. Validity of the executive function theory of attention-deficit/hyperactivity disorder: a meta-analytic review. Biol Psychiatry. 2005;57(11): 1336–1346
   PubMed Web of Science ®Google Scholar
• . Barkley RA. Behavioral inhibition, sustained attention, and executive functions: constructing a unifying theory of ADHD. Psychol Bull. 1997;121(1):65–94
   PubMed Web of Science ®Google Scholar
• . Spencer TJ. ADHD and comorbidity in childhood. J Clin Psychiatry. 2006;67( suppl 8):27–31
   PubMed Web of Science ®Google Scholar
• . Barkley RA. Attention-deficit/hyperactivity disorder. In: Wolfe DA, Mash EJ, eds. Behavioral and Emotional Disorders in Adolescents: Nature, Assessment, and Treatment. New York, NY: Guilford Press; 2006:91–152
   Google Scholar
• . Loe IM, Feldman HM. Academic and educational outcomes of children with ADHD. Ambul Pediatr. 2007;7( 1 suppl):82–90
   PubMedGoogle Scholar
• . Biederman J, Faraone SV, Lapey K. Comorbidity of diagnosis in attention-deficit hyperactivity disorder. In: Weiss G, ed. Child and Adolescent Psychiatry Clinics of North America: Attention deficit Hyperactivity Disorder. Philadelphia, PA: Saunders; 1992: 335–360
   Google Scholar
• . Mayes SD, Calhoun SL. Frequency of reading, math, and writing disabilities in children with clinical disorders. Learn Individ Differ. 2006;16(2):145–157
   Web of Science ®Google Scholar
• . Hall A. Specific learning difficulties. Psychiatry. 2008;7(6):260–265
   Google Scholar
• . Semrud–Clikeman M. Neuropsychological aspects for evaluating learning disabilities. J Learn Disabil. 2005;38(6):563–568
   PubMedGoogle Scholar
• . Isles AR, Humby T. Modes of imprinted gene action in learning disability. J Intellect Disabil Res. 2006;50(pt 5):318–325
   PubMedGoogle Scholar
• . Rhee SH, Willcutt EG, Hartman CA, Pennington BF, DeFries JC. Test of alternative hypotheses explaining the comorbidity between attention-deficit/hyperactivity disorder and conduct disorder. J Abnorm Child Psychol. 2008;36(1):29–40
   PubMedGoogle Scholar
• . DuPaul GJ, Stoner G. ADHD in the Schools: Assessment and Intervention Strategies. 2nd ed. New York, NY: Guilford Press; 2004
   Google Scholar
• . Goldstein S, Naglieri J. The school neuropsychology of ADHD: theory, assessment, and intervention. Psychol School. 2008;45(9):859–874
   Google Scholar
• . Roth RM, Saykin AJ. Executive dysfunction in attention-deficit/hyperactivity disorder: cognitive and neuroimaging findings. Psychiatr Clin North Am. 2004;27(1):83–96
   PubMed Web of Science ®Google Scholar
• . Hale JB, Reddy LA, Wilcox G, . Assessment and intervention for children with ADHD and other frontal-striatal circuit disorders. In: Miller DC, ed. Best Practices in School Neuropsychology: Guidelines for Effective Practice, Assessment and Evidence-Based Interventions. Hoboken, NJ: John Wiley and Sons; 2009:225–280
   Google Scholar
• . Hale JB, Yim M, Schneider AN, . Cognitive and neuropsychological assessment of ADHD: redefining a disruptive behavior disorder. In: Flanagan D P, Harrison P, eds. Contemporary Intellectual Assessment: Theories, Tests, and Issues. 3rd ed. New York, NY: Guilford Press; 2012
   Google Scholar
• . Manor I, Meidad S, Zalsman G, Zemishlany Z, Tyano S, Weizman A. Objective versus subjective assessment of methylphenidate response. Child Psychiatry Hum Dev. 2008;39(3):273–282
   PubMedGoogle Scholar
• . Lichter DG, Cummings JL, eds. Frontal-Subcortical Circuits in Psychiatric and Neurological Disorders. New York, NY: Guilford Press; 2001
   Google Scholar
• . Hale JB, Fiorello CA, Brown L. Determining medication treatment effects using teacher ratings and classroom observations of children with ADHD: does neuropsychological impairment matter? Education Child Psychol. 2005;22(2):39–61
   Google Scholar
• . Dickstein SG, Bannon K, Castellanos FX, Milham MP. The neural correlates of attention deficit hyperactivity disorder: an ALE meta-analysis. J Child Psychol Psychiatry. 2006;47(10):1051–1062
   PubMed Web of Science ®Google Scholar
• . Vaidya CJ, Stollstroff M. Cognitive neuroscience of attention deficit hyperactivity disorder: current status and working hypotheses. Dev Disabil Res Rev. 2008;14(4):261–267
   PubMedGoogle Scholar
• . Arnsten AF. Toward a new understanding of attention-deficit hyperactivity disorder pathophysiology. CNS Drugs. 2009;23( suppl 1): 33–41
   PubMed Web of Science ®Google Scholar
• . Arnsten AF. The emerging neurobiology of attention deficit hyperactivity disorder: the key role of the prefrontal association cortex. J Pediatr. 2009; 154(5):I–S43
   PubMedGoogle Scholar
• . Arnsten AF, Li BM. Neurobiology of executive functions: catecholamine influences on prefrontal cortical functions. Biol Psychiatry. 2005; 57(11):1377–1384
   PubMed Web of Science ®Google Scholar
• . Arnsten AF, Pliszka SR. Catecholamine influences on prefrontal cortical function: relevance to treatment of attention deficit/hyperactivity disorder and related disorders. Pharmacol Biochem Behav. 2011;99(2):211–216
   PubMed Web of Science ®Google Scholar
• . Volkow ND, Wang GJ, Fowler JS, . Therapeutic doses of oral methylphenidate significantly increase extracellular dopamine in the human brain. J NeuroSci. 2001;21(2):RC121
   PubMed Web of Science ®Google Scholar
• . Volkow ND, Wang GJ, Kollins SH, . Evaluating dopamine reward pathway in ADHD: clinical implications. JAMA. 2009;302(10): 1084–1091
   PubMed Web of Science ®Google Scholar
• . Voeller KK. Attention-deficit/hyperactivity disorder as a frontal-subcortical disorder. In: Lichter DG, Cummings JL, eds. Frontal-Subcortical Circuits in Psychiatric and Neurological Disorders. New York, NY: Guilford Press; 2001:334–371
   Google Scholar
• . Hood J, Baird G, Rankin PM, Isaacs E. Immediate effects of methylphenidate on cognitive attention skills of children with attention-deficit-hyperactivity disorder. Dev Med Child Neurol. 2005;47(6): 408–414
   PubMed Web of Science ®Google Scholar
• . Zelazo PD, Müller U. Executive function in typical and atypical development. In: Goswami U, ed. The Wiley-Blackwell Handbook of Childhood Cognitive Development. 2nd ed. Malden, MA: Wiley-Blackwell; 2011:574–603
   Google Scholar
• . Castellanos FX, Tannock R. Neuroscience of attention-deficit/hyperactivity disorder: the search for endophenotypes. Nat Rev NeuroSci. 2002;3(8):617–628
   PubMed Web of Science ®Google Scholar
• . Nigg JT, Willcutt EG, Doyle AE, Sonuga–Barke EJ. Causal heterogeneity in attention-deficit/hyperactivity disorder: do we need neuropsychologically impaired subtypes? Biol Psychiatry. 2005;57(11): 1224–1230
   PubMed Web of Science ®Google Scholar
• . Castellanos FX, Sonuga–Barke EJ, Milham MP, Tannock R. Characterizing cognition in ADHD: beyond executive dysfunction. Trends Cogn Sci. 2006;10(3):117–123
   PubMed Web of Science ®Google Scholar
• . Solanto MV, Abikoff H, Sonuga–Barke E, . The ecological validity of delay aversion and response inhibition as measures of impulsivity in AD/HD: a supplement to the NIMH multimodal treatment study of AD/HD. J Abnorm Child Psychol. 2001;29(3):215–228
   PubMed Web of Science ®Google Scholar
• . Fabiano GA, Pelham WE Jr, Coles EK, Gnagy EM, Chronis–Tuscano A, O'Connor BC. A meta-analysis of behavioral treatments for attention-deficit/hyperactivity disorder. Clin Psychol Rev. 2009; 29(2):129–140
   PubMed Web of Science ®Google Scholar
• . Engert V, Pruessner JC. Dopaminergic and noradrenergic contributions to functionality in ADHD: the role of methylphenidate. Curr Neuropharmacol. 2008;6(4):322–328
   PubMedGoogle Scholar
• . Van der Oord S, Prins PJ, Oosterlaan J, Emmelkamp PM. Efficacy of methylphenidate, psychosocial treatments and their combination in school-aged children with ADHD: a meta-analysis. Clin Psychol Rev. 2008;28(5):783–800
   PubMed Web of Science ®Google Scholar
• . Berridge CW, Devilbiss DM, Andrzejewski ME, . Methylphenidate preferentially increases catecholamine neurotransmission within prefrontal cortex at low doses that enhance cognitive function. Biol Psychiatry. 2006;60(10):1111–1120
   PubMed Web of Science ®Google Scholar
• . Li D, Sham PK, Owen MJ, He L. Meta-analysis shows significant association between dopamine system genes and attention deficit hyperactivity disorder (ADHD). Hum Mol Genet. 2006;15(14): 2276–2284
   PubMed Web of Science ®Google Scholar
• . Floresco SB, Magyar O. Mesocortical dopamine modulation of executive functions: beyond working memory. Psychopharmacology (Berl). 2006;188(4):567–585
   PubMed Web of Science ®Google Scholar
• . Berridge CW, Devilbiss DM. Psychostimulants as cognitive enhancers: the prefrontal cortex, catecholamines, and attention-deficit/hyperactivity disorder. Biol Psychiatry. 2011;69(12):e101–e111
   PubMed Web of Science ®Google Scholar
• . Arnsten AF. Stimulants: therapeutic actions in ADHD. Neuropsychopharmacology. 2006;31(11):2376–2383
   PubMed Web of Science ®Google Scholar
• . Konrad K, Gunther T, Hanisch C, Herpertz–Dahlmann B. Differential effects of methylphenidate on attentional functions in children with attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry. 2004;43(2):191–198
   PubMed Web of Science ®Google Scholar
• . Hale JB, Reddy LA, Semrud–Clikeman M, . Executive impairment determines ADHD medication response: implications for academic achievement. J Learn Disabil. 2011;44(2):196–212
   PubMed Web of Science ®Google Scholar
• . Chacko A, Pelham WE, Gnagy EM, . Stimulant medication effects in a summer treatment program among young children with attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry. 2006;44(3):249–257
   Google Scholar
• . Pliszka SR, Liotti M, Bailey BY, Perez R 3rd, Glahn D, Semrud–Clikeman M. Electrophysiological effects of stimulant treatment on inhibitory control in children with attention-deficit/hyperactivity disorder. J Child Adolesc Psychopharmacol. 2007;17(3):356–366
   PubMedGoogle Scholar
• . Pearson DA, Santos CW, Roache JD, . Treatment effects of methylphenidate on behavioral adjustment in children with mental retardation and ADHD. J Am Acad Child Adolesc Psychiatry. 2003;42(2): 209–216
   PubMed Web of Science ®Google Scholar
• . Waxmonsky J, Pelham WE, Gnagy E, . The efficacy and tolerability of methylphenidate and behavior modification in children with attention-deficit/hyperactivity disorder and severe mood dysregulation. J Child Adolesc Psychopharmacol. 2008;18(6):573–588
   PubMedGoogle Scholar
• . Conners CK. Forty years of methylphenidate treatment in attention-deficit/hyperactivity disorder. J Atten Disord. 2002;6( suppl 1):S17–S30
   PubMedGoogle Scholar
• . Pearson DA, Santos CW, Casat CC, . Treatment effects of methylphenidate on cognitive functioning in children with mental retardation and ADHD. J Am Acad Child Adolesc Psychiatry. 2004;43(6): 677–685
   PubMed Web of Science ®Google Scholar
• . Rapport MD, Denney C, DuPaul GJ, Gardner MJ. Attention deficit disorder and methylphenidate: normalization rates, clinical effectiveness, and response prediction in 76 children. J Am Acad Child Adolesc Psychiatry. 1994;33(6):882–893
   PubMed Web of Science ®Google Scholar
• . Hoeppner JB, Hale JB, Bradley AM, . A clinical protocol for determining methylphenidate dosage levels in ADHD. J Attention Disord. 1997;2(1):19–30
   Google Scholar
• . Sprague RL, Sleator EK. Methylphenidate in hyperkinetic children: differences in dose effects on learning and social behavior. Science. 1977;198(4323):1274–1276
   PubMed Web of Science ®Google Scholar
• . Pietrzak RH, Mollica CM, Maruff P, Snyder PJ. Cognitive effects of immediate-release methylphenidate in children with attention-deficit/hyperactivity disorder. Neurosci Biobehav Rev. 2006;30(8):1225–1245
   PubMed Web of Science ®Google Scholar
• . Swanson J, Baler RD, Volkow ND. Understanding the effects of stimulant medications on cognition in individuals with attention-deficit hyperactivity disorder: a decade of progress. Neuropsychopharmacology. 2011;36(1):207–226
   PubMed Web of Science ®Google Scholar
• . Kemner C, Jonkman LM, Kenemans JL, Böcker KB, Verbaten MN, Engeland H. Sources of auditory selective attention and the effects of methylphenidate in children with attention-deficit/hyperactivity disorder. Biol Psychiatry. 2004;55(7):776–778
   PubMedGoogle Scholar
• . Kobel M, Bechtel N, Weber P, . Effects of methylphenidate on working memory functioning in children with attention deficit/hyperactivity disorder. Eur J Paediatr Neurol. 2008;13(6):516–523
   PubMedGoogle Scholar
• . Langleben DD, Monterosso L, Elman I, Ash B, Krikorian G, Austin G. Effects of methylphenidate on Stroop Color-Word task performance in children with attention-deficit/hyperactivity disorder. Psychiatry Res. 2006;141(3):315–320
   PubMedGoogle Scholar
• . Semrud–Clikeman M, Pliszka S, Liotto M. Executive functioning in children with attention-deficit hyperactivity disorder: combined type with and without a stimulant medication history. Neuropsychology. 2008;22(3):329–340
   PubMed Web of Science ®Google Scholar
• . Wilson HK, Cox DJ, Merkel RL, Moore M, Coghill D. Effect of extended release stimulant-based medications on neuropsychological functioning among adolescents with attention-deficit/hyperactivity disorder. Arch Clin Neuropsychol. 2006;21(8):797–807
   PubMed Web of Science ®Google Scholar
• . DeVito EE, Blackwell AD, Kent L, . The effects of methylphenidate on decision making in attention-deficit/hyperactivity disorder. Biol Psychiatry. 2008;64(7):636–639
   PubMedGoogle Scholar
• . Rhodes SM, Coghill DR, Matthews K. Acute neuropsychological effects of methylphenidate in stimulant drug-naïve boys with ADHD II—broader executive and non-executive domains. J Child Psychol Psychiatry. 2006;47(11):1184–1194
   PubMed Web of Science ®Google Scholar
• . Kühle H, Kinkelbur J, Andes K, . Self-regulation of visual attention and facial expression of emotions in ADHD children. J Atten Disord. 2007;10(4):350–358
   PubMedGoogle Scholar
• . Tannock R, Schachar R, Logan G. Methylphenidate and cognitive flexibility: dissociated dose effects in hyperactive children. J Abnorm Child Psychol. 1995;23(2):235–266
   PubMedGoogle Scholar
• . Douglas VI, Barr RG, Desilets J, Sherman E. Do high doses of stimulants impair flexible thinking in attention-deficit hyperactivity disorder? J Am Acad Child Adolesc Psychiatry. 1995;34(7):879–885
   Google Scholar
• . Barkley RA, DuPaul GJ, McMurray MB. Attention deficit disorder with and without hyperactivity: clinical response to three dose levels of methylphenidate. Pediatr. 1991;87(4):519–531
   PubMed Web of Science ®Google Scholar
• . Advokat C. What exactly are the benefits of stimulants for ADHD? J Atten Disord. 2009;12(6):495–498
   PubMed Web of Science ®Google Scholar
• . Powers RL, Marks DJ, Miller CJ, Newcorn JH, Halperin JM. Stimulant treatment in children with attention-deficit/hyperactivity disorder moderates adolescent academic outcome. J Child Adolesc Psychopharmacol. 2008;18(5):449–459
   PubMed Web of Science ®Google Scholar
• . A 14-month randomized clinical trial of treatment strategies for attention-deficit/hyperactivity disorder. The MTA Cooperative Group. Multimodal Treatment Study of Children with ADHD. Arch Gen Psychiatry. 1999;56(12):1073–1086
   PubMed Web of Science ®Google Scholar
• . Jensen PS, Arnold LE, Swanson JM, . 3-year follow up of the NIMH MTA study. J Am Acad Child Adolesc Psychiatry. 2007;46(8):989–1002
   PubMed Web of Science ®Google Scholar
• . Molina BS, Hinshaw SP, Swanson JM, ; MTA Cooperative Group. The MTA at 8 years: prospective follow-up of children treated for combined-type ADHD in a multisite study. J Am Acad Child Adolesc Psychiatry. 2009;48(5):484–500
   PubMed Web of Science ®Google Scholar
• . Scheffler RM, Brown TT, Fulton BD, Hinshaw SP, Levine P, Stone S. Positive association between attention-deficit/hyperactivity disorder medication use and academic achievement during elementary school. Pediatrics. 2009;123(5):1273–1279
   PubMed Web of Science ®Google Scholar
• . Greenhill LL, Swanson JM, Vitiello B, . Impairment and deportment responses to different methylphenidate doses in children with ADHD: the MTA titration trial. J Am Acad Child Adolesc Psychiatry. 2001;40(2):180–187
   PubMed Web of Science ®Google Scholar
• . Hale JB, Hoeppner JB, DeWitt MB, Coury DL, Ritacco DG, Trommer B. Evaluating medication response in ADHD: cognitive, behavioral, and single-subject methodology. J Learn Disabil. 1998; 31(6):595–607
   PubMedGoogle Scholar
• . Reddy LA, Hale J. Inattentiveness. In: Eisen AR, ed. Treating Childhood Behavioral and Emotional Disorders: A Step-By-Step Evidence-Based Approach. New York, NY: Guilford Press; 2007:156–211
   Google Scholar
• . Achenbach TM. Integrative Guide for the 1991 CBCL/4–18, YSR, and TRF Profiles. Burlington, VT: University of Vermont, Department of Psychiatry; 1991
   Google Scholar
• . Conners K. Conners' Parent and Teacher Rating Scale–Revised. North Tonawanda, NY: Multi-Health Systems; 1997
   Google Scholar
• . DuPaul GJ, Rapport MD, Perriello LM. Teacher ratings of academic skills: the development of the Academic Performance Rating Scale. School Psych Rev. 1991;20(2):284–300
   Web of Science ®Google Scholar
• . DuPaul GJ, Barkley RA. Situational variability of attention problems: Psychometric properties of the Revised Home and School Situations Questionnaires. J Clin Child Psychol. 1992;21:178–188
   Web of Science ®Google Scholar
• . Barkley RA. Attention-deficit Hyperactivity Disorder: A Handbook for Diagnosis and Treatment. New York, NY: Guilford Press; 1990
   Google Scholar
• . May RB, Masson MEJ, Hunter MA, Wells J. NPStat 3.01 [Computer software]. Victoria, Canada: University of Victoria; 1990
   Google Scholar
• . Trommer BL, Hoeppner JB, Zecker SG. The go-no go test in attention deficit disorder is sensitive to methylphenidate. J Child Neurol. 1991;6( suppl 1):S128–S131
   PubMed Web of Science ®Google Scholar
• . Golden JC. Stroop Color and Word Test. Chicago, IL: Stoelting; 1978
   Google Scholar
• . Reynold CR, Bigler ED. Test of Memory and Learning. Austin, TX: Pro-Ed; 1994
   Google Scholar
• . Newby RF. Wisconsin Selective Reminding Test. Milwaukee, WI: Medical College of Wisconsin; 1999
   Google Scholar
• . Reitan RM, Wolfson D. Neuroanatomy and Neuropathology: A Guide for Neuropsychologists. Tucson, AZ: Neuropsychology Press; 1985
   Google Scholar
• . Conners K. Conners' Continuous Performance Test–II User's Manual. Toronto, Ontario, Canada: Multi-Health Systems; 2000
   Google Scholar
• . Pennington BF, Ozonoff S. Executive functions and developmental psychopathology. J Child Adolesc Psychiatr. 1996;37(1):51–87
   Google Scholar
• . Sergeant JA, Geurts H, Oosterlaan J. How specific is a deficit of executive functioning for attention-deficit/hyperactivity disorder? Behav Brain Res. 2002;130(1–2):3–28
   PubMed Web of Science ®Google Scholar
• . Hale JB, Mulligan CA, Simmerman KL. Quantifying Medication Response in ADHD: Does Neuropsychological Impairment Matter? Poster presented: at 34th Annual Meeting of the International Neuropsychological Society; Boston, MA. 2006
   Google Scholar
• . Kelly C, Sonuga–Barke EJ, Scheres A, Castellanos FX. Functional neuroimaging of the reward and motivational pathway in ADHD. In: Fitzgerald M, Bellgrove M, Gill M, eds. Handbook of Attention deficit Hyperactivity Disorder. Hoboken, NJ: John Wiley and Sons; 2007:209–235
   Google Scholar
• . Figner B, Mackinlay RJ, Wilkening F, Weber EU. Affective and deliberative processes in risky choice: age differences in risk taking in the Columbia Card Task. J Exp Psychol Learn Mem Cogn. 2009;35(3):709–730
   PubMed Web of Science ®Google Scholar
• . Roiser JP, Cannon DM, Ghandi SK, . Hot and cold cognition in unmedicated depressed subjects with bipolar disorder. Bipolar Disord. 2009;11(2):178–189
   PubMedGoogle Scholar
• . Steinberg L. A social neuroscience perspective on adolescent risk-taking. Dev Rev. 2008;28(1):78–106
   PubMed Web of Science ®Google Scholar
• . Teicher MH, Polcari A, McGreenery CE. Utility of objective measures of activity and attention in the assessment of therapeutic response to stimulants in children with attention-deficit/hyperactivity disorder. J Child Adolesc Psychopharmacol. 2008;18(3):265–270
   PubMedGoogle Scholar
• . Balthazor MJ, Wagner RK, Pelham WE. The specificity of the effects of stimulant medication on classroom learning-related measures of cognitive processing for attention deficit disorder children. J Abnorm Child Psychol. 1991;19(1):35–52
   PubMedGoogle Scholar
• . Frankenberger W, Cannon C. Effects of Ritalin on academic achievement from first to fifth grade. Int J Disability Dev Educ. 1999;46: 199–221
   Google Scholar
• . Decker SL, Hill SK, Dean RS. Evidence of construct similarity in executive functions and fluid reasoning abilities. Int J NeuroSci. 2007;117(6):735–748
   PubMed Web of Science ®Google Scholar
• . Denckla MB. Biological correlates of learning and attention: what is relevant to learning disability and attention-deficit/hyperactivity disorder? J Dev Behav Pediatr. 1996;17(2):114–119
   PubMedGoogle Scholar
• . Brown RT, LaRosa A. Recent developments in the pharmacotherapy of attention deficit/hyperactivity disorder (ADHD). Prof Psychol Res Pr. 2002;33:591–595
   Web of Science ®Google Scholar
• . Abikoff H, Hechtman L, Klein RG, . Symptomatic improvement in children with ADHD treated with long-term methylphenidate and multimodal psychosocial treatment. J Am Acad Child Adolesc Psychiatry. 2004;43(7):802–811
   PubMed Web of Science ®Google Scholar