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Clinical Focus: Pain Management, Rare Diseases, and Allergies

Role of Indomethacin in Acute Pain and Inflammation Management: A Review of the Literature

, MD & , MD

References

  • . Indocin (indomethacin) suspension [package insert]. Philadelphia, PA: Iroko Pharmaceuticals LLC; 2008
  • . Indocin (indomethacin) injection, powder, lyophilized, for solution [package insert]. Deerfield, IL: Lundbeck, Inc.; 2010
  • . Indocin (indomethacin) suppository [package insert]. Philadelphia, PA: Iroko Pharmaceuticals, LLC.; 2011
  • . Ketorolac I.V./I.M. Tromethamine [Prescribing Information]. Lake Forest, IL: Hospira Inc.; 2005
  • . Voltaren Gel [Prescribing Information]. Parsippany, NJ: Novartis Consumer Health Inc.; Parsippany, NJ; 2009
  • . Rostom A, Goldkind L, Laine L. Nonsteroidal anti-inflammatory drugs and hepatic toxicity: a systematic review of randomized controlled trials in arthritis patients. Clin Gastroenterol Hepatol. 2005;3(5): 489–498
  • . Coxib, traditional NSAID trialists' (CNT) collaboration. Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials. Lancet. 2013;382(9894):769–779
  • . McGettigan P, Henry D. Use of non-steroidal anti-inflammatory drugs that elevate cardiovascular risk: an examination of sales and essential medicines lists in low-, middle-, and high-income countries. PLoS Med. 2013;10(2):e1001388
  • . Brater DC. Anti-inflammatory agents and renal function. Semin Arthritis Rheum. 2002;32(3 Suppl 1):33–42
  • . Indomethacin capsule [package insert]. Eatontown, NJ: Heritage Pharmaceuticals, Inc.; 2010 (revised January 2014)
  • . The United States Pharmacopeial Convention. Revision Bulletin. January 1, 2012. Indomethacin Extended-Release Capsules. http://www.usp.org/sites/default/files/usp_pdf/EN/USPNF/revisions/m40421-indomethacin_extended-release_capsules.pdf. Accessed April 28, 2014
  • . Vane JR, Botting RM. The mechanism of action of aspirin. Thromb Res. 2003;110(5–6):255–258
  • . Bayer Safety Coated Aspirin. Delayed Release Enteric Aspirin for Oral Administration [comprehensive prescribing information]. Morristown, NJ: Bayer
  • . Steen KH, Reeh PW, Kreysel HW. Topical acetylsalicylic, salicylic acid and indomethacin suppress pain from experimental tissue acidosis in human skin. Pain. 1995;62(3):339–347
  • . De Benedittis G, Lorenzetti A. Topical aspirin/diethyl ether mixture versus indomethacin and diclofenac/diethyl ether mixtures for acute herpetic neuralgia and postherpetic neuralgia: a double-blind crossover placebo-controlled study. Pain. 1996;65(1):45–51
  • . Valtonen EJ, Busson M. A comparative study on ibuprofen (Brufen) and indomethacin in non-articular rheumatism. Scand J Rheumatol. 1978;7(3):183–187
  • . McArthur AW, Ferry DG, Palmer DG. A comparative study of indomethacin and ibuprofen. Med J Aust. 1979;1(1):25–27
  • . Gookin KS, Forman ES, Vecchio TJ, Wiser WL, Morrison JC. Comparative efficacy of ibuprofen, indomethacin, and placebo in the treatment of primary dysmenorrhea. South Med J. 1983;76(11):1361–1362, 1367
  • . Duke O, Zecler E, Grahame R. Anti-inflammatory drugs in periarthritis of the shoulder: a double-blind, between-patient study of naproxen versus indomethacin. Rheumatol Rehabil. 1981;20(1):54–59
  • . EC-NAPROSYN® (naproxen delayed-relase capsules), NAPROSYN® (naproxen tablets), ANAPROX®/ANAPROX® DS (naproxen sodium tablets), NAPROSYN® (naproxen suspension) [package insert]. 1999; Nutley, NJ: Roche Laboratories Inc. http://www.accessdata.fda.gov/drugsatfda_docs/label/2008/017581s110,18164s60,18965s18,20067s17lbl.pdf. Acessed April 28, 2014
  • . Barnes CG, Goodman HV, Eade AW, . A double-blind comparison of naproxen with indomethacin in osteoarthrosis. J Clin Pharmacol. 1975;15(4 Pt 2):347–354
  • . Wester JU, Haerslev T, Mathiesen FK, Jespersen SM, Hansen TM. Naproxen versus indomethacin as night-time medication for patients with rheumatoid arthritis. Ugeskr Laeger. 1991;153(27):1937–1939
  • . McGettigan P, Henry D. Cardiovascular risk with non-steroidal anti-inflammatory drugs: systematic review of population-based controlled observational studies. PLoS Med. 2011;8(9):e1001098
  • . O'Riordin M. FDA advisory panel votes against CV safety claim for naproxen. Heartwire. http://www.medscape.com/viewarticle/820470. Accessed May 14, 2014
  • . Meloxicam. Prescribing information. http://www.accessdata.fda.gov/drugsatfda_docs/label/2008/020938s018,021530s006 lbl.pdf. Accessed April 28, 2014
  • . Engelhardt G, Homma D, Schlegel K, Utzmann R, Schnitzler C. Anti-inflammatory, analgesic, antipyretic and related properties of meloxicam, a new non-steroidal anti-inflammatory agent with favourable gastrointestinal tolerance. Inflamm Res. 1995;44(10):423–433
  • . Degner F, Sigmund R, Zeidler H. Efficacy and tolerability of meloxicam in an observational, controlled cohort study in patients with rheumatic disease. Clin Ther. 2000;22(4):400–410
  • . Piroxicam prescribing information. http://www.accessdata.fda.gov/Scripts/cder/drugsatfda/index.cfm?fuseaction = Search.DrugDetails. Accessed April 28, 2014
  • . Videman T, Osterman K. Double-blind parallel study of piroxicam versus indomethacin in the treatment of low back pain. Ann Clin Res. 1984;16(3):156–160
  • . Uddenfeldt P, Leden I, Rubin B. A double-blind comparison of oral ketoprofen “controlled release” and indomethacin suppository in the treatment of rheumatoid arthritis with special regard to morning stiffness and pain on awakening. Curr Med Res Opin. 1993;13(3):127–132
  • . Franchi R, Liverta C, Pollini C, Pontiroli AE. Parenteral administration of ketoprofen in osteoarthritis: a double-blind trial versus the N-methyl-d-glucamine salt of indomethacin. Scand J Rheumatol Suppl. 1979;(26):1–7
  • . El-Ghobarey AF, Rennie JA, Hadidi T, Hamid HA, Mavrikakis M. A comparative trial of large doses of ketoprofen and indomethacin in the treatment of rheumatoid arthritis. Curr Med Res Opin. 1976;4(6):432–435
  • . Franchi R, Viara M, Liverta C, Pollini C, Pontiroli AE. Ketoprofen and indomethacin in the treatment of rheumatoid arthritis: a double-blind cross-over trial. Eur J Clin Pharmacol. 1975;8(3–4):205–208
  • . Turner GA, Anson N, Williamson R. A comparison of intramuscular ketorolac with indomethacin suppositories in the treatment of pain after oral surgery. Anaesth Intensive Care. 1996;24(6):665–668
  • . Morley-Forster P, Newton PT, Cook MJ. Ketorolac and indomethacin are equally efficacious for the relief of minor postoperative pain. Can J Anaesth. 1993;40(12):1126–1130
  • . Mattila MA, Ahlstrom-Bengs E, Pekkola P. Intravenous indomethacin or oxycodone in prevention of post-operative pain. Br Med J (Clin Res Ed). 1983;287(6398):1026
  • . Laitinen J, Nuutinen L, Kiiskila EL, Freudenthal Y, Ranta P, Karvonen J. Comparison of intravenous diclofenac, indomethacin and oxycodone as post-operative analgesics in patients undergoing knee surgery. Eur J Anaesthesiol. 1992;9(1):29–34
  • . Cordell WH, Larson TA, Lingeman JE, . Indomethacin suppositories versus intravenously titrated morphine for the treatment of ureteral colic. Ann Emerg Med. 1994;23(2):262–269
  • . Ambrose FP. A retrospective study of the effect of postoperative indomethacin rectal suppositories on the need for narcotic analgesia in patients who had a cesarean delivery while they were under regional anesthesia. Am J Obstet Gynecol. 2001;184(7):1544–1548
  • . Tramadol [package insert.] http://www.accessdata.fda.gov/Scripts/cder/drugsatfda/index.cfm?fuseaction = Search.DrugDetails. Accessed April 28, 2014
  • . Khazin V, Weitzman S, Rozenzvit-Podles E, . Postoperative analgesia with tramadol and indomethacin for diagnostic curettage and early termination of pregnancy. Int J Obstet Anesth. 2011;20(3):236–239
  • . PENNSAID® (diclofenac sodium topical solution) 1.5% [package insert]. Mallinckrodt, Inc; 2013
  • . Altman R, Daniels S, Young CL. Indomethacin submicron particle capsules provide effective pain relief in patients with acute pain: a phase 3 study. Phys Sportsmed. 2013;41(4):7–15
  • . TIVORBEXtrade (indomethacin) capsules [package insert]. Iroko Pharmaceuticals, LLC; 2014

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