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Original Articles

Galactosaminogalactan of Aspergillus fumigatus, a bioactive fungal polymer

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Pages 572-580 | Received 10 Nov 2015, Accepted 31 Jan 2016, Published online: 20 Jan 2017

Literature cited

  • ArakiYTakadaHFujiiNItoE. 1979. A pathway of polygalactosamine formation in Aspergillus parasiticus: enzymatic deacetylation of N-acetylated polygalactosamine. Eur J Biochem 102:35–42, doi:10.1111/j.1432-1033.1979.tb06260.x
  • BakerLGSpechtCADonlinMJLodgeJK. 2007. Chitosan, the deacetylated form of Chitin, is necessary for cell wall integrity in Cryptococcus neoformans. Eukaryot Cell 6: 855–867, doi:10.1128/EC.00399-06
  • BakerLGSpechtCALodgeJK. 2011. Cell-wall chitosan is necessary for virulence in the opportunistic pathogen Cryptococcus neoformans. Eukaryot Cell 10:1264–1268, doi:10.1128/EC.05138-11
  • BamfordNCSnarrBDGravelatFNLittleDJLeeMJZachariasCAChabotJCGellerAMBaptistaSDBakerPRobinsonHHowellPLSheppardDC. 2015. Sph3 is a glycoside hydrolase required for the biosynthesis of galactosaminogalactan in Aspergillus fumigatus. J Biol Chem 290:27438–27450, doi:10.1074/jbc.M115.679050
  • BardalayePCNordinJH. 1976. Galactosaminogalactan from cell walls of Aspergillus niger. J Bacteriol 125:655–669.
  • BeaussartAEl-Kirat-ChatelSFontaineTLatgéJ-PDufrêneYF. 2015. Nanoscale biophysical properties of the cell surface galactosaminogalactan from the fungal pathogen Aspergillus fumigatus. Nanoscale 7:14996–15004, doi:10.1039/C5NR04399A
  • BeauvaisABozzaSKniemeyerOFormosaCBalloyVHenryCRobersonRWDagueEChignardMBrakhageAARomaniLLatgéJ-P. 2013. Deletion of the α-(1,3)-glucan synthase genes induces a restructuring of the conidial cell wall responsible for the avirulence of Aspergillus fumigatus. PLoS Pathog 9:e1003716, doi:10.1371/journal.ppat.1003716
  • BleauCMongesARashidanKLaverdureJ-PLacroixMvan CalsterenM-RMilletteMSavardRLamontagneL. 2010. Intermediate chains of exopolysaccharides from Lactobacillus rhamnosus RW-9595M increase IL-10 production by macrophages. J Appl Microbiol 108: 666–675, doi:10.1111/j.1365-2672.2009.04450.x
  • BorregaardN. 2010. Neutrophils, from marrow to microbes. Immunity 33:657–670, doi:10.1016/j.immuni.2010.11.011
  • BozzaSClavaudCGiovanniniGFontaineTBeauvaisASarfatiJD’AngeloCPerruccioKBonifaziPZagarellaSMorettiSBistoniFLatgéJ-PRomaniL. 2009. Immune sensing of Aspergillus fumigatus proteins, glycolipids and polysaccharides and the impact on Th Immunity and vaccination. J Immunol 183:2407–2414, doi:10.4049/jimmunol.0900961.
  • BrakhageAA. 2013. Regulation of fungal secondary metabolism. Nat Rev Microbiol 11:21–32, doi:10.1038/nrmicro2916
  • de BritoTVda PrudêncioRSSalesABdas Vieira JúniorFCCandeiraSJNFrancoÁXAragãoKSde RibeiroRAPonte de SouzaMHLde ChavesLSFreitasALPMedeirosJ-VRdos Reis BarbosaAL. 2013. Anti-inflammatory effect of a sulphated polysaccharide fraction extracted from the red algae Hypnea musciformis via the suppression of neutrophil migration by the nitric oxide signalling pathway. J Pharm Pharmacol 65:724–733, doi:10.1111/jphp.12024
  • de LucaASmeekensSPCasagrandeAIannittiRConwayKLGresnigtMSBegunJPlantingaTSJoostenLABvan der MeerJWMChamilosGNeteaMGXavierRJDinarelloCARomaniLvan de VeerdonkFL. 2014. IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans. Proc Natl Acad Sci U S A 111: 3526–3531, doi:10.1073/pnas.1322831111
  • de SousaAASBenevidesNMBde Freitas PiresAFiúzaFPQueirozMGRMoraisTMFPereiraMGAssreuyAMS. 2013. A report of a galactan from marine alga Gelidium crinale with in vivo anti-inflammatory and antinociceptive effects. Fundam Clin Pharmacol 27:173–180, doi:10.1111/j.1472-8206.2011.01001.x
  • DinarelloCASimonAvan der MeerJWM. 2012. Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases. Nat Rev Drug Discov 11:633–652, doi:10.1038/nrd3800
  • DistlerJJRosemanS. 1960. Galactosamine polymers produced by Aspergillus parasiticus. J Biol Chem 235: 2538–2541.
  • FlemmingH-CWingenderJ. 2010. The biofilm matrix. Nat Rev Microbiol 8:623–633, doi:10.1038/nrmicro2415
  • FontaineTDelangleASimenelCCoddevilleBvan VlietSJvan KooykYBozzaSMorettiSSchwarzFTrichotCAebiMDelepierreMElbimCRomaniLLatgéJ-P. 2011. Galactosaminogalactan, a new immunosuppressive polysaccharide of Aspergillus fumigatus. PLoS Pathog 7:e1002372, doi:10.1371/journal.ppat.1002372
  • GangneuxJ-PLavardeDBretagneSGuiguenCGandemerV. 2002. Transient aspergillus antigenaemia: think of milk. Lancet 359:1251, doi:10.1016/S0140-6736(02)08238-7
  • GibbonsJGBeauvaisABeauRMcGaryKLLatgéJ-PRokasA. 2012. Global transcriptome changes underlying colony growth in the opportunistic human pathogen Aspergillus fumigatus. Eukaryot Cell 11:68–78, doi:10.1128/EC.05102-11
  • GlasgowJEReissigJL. 1974. Interaction of galactosaminoglycan with Neurospora conidia. J Bacteriol 120:759–766.
  • GravelatFNBeauvaisALiuHLeeMJSnarrBDChenDXuWKravtsovIHoareauCMQVanierGUrbMCampoliPAbdallahQALehouxMChabotJCOuimetM-CBaptistaSDFritzJHNiermanWCLatgéJPMitchellAPFillerSGFontaineTSheppardDC. 2013. Aspergillus galactosaminogalactan mediates adherence to host constituents and conceals hyphal β-glucan from the immune system. PLoS Pathog 9:e1003575, doi:10.1371/journal.ppat.1003575
  • GresnigtMSBozzaSBeckerKLJoostenLABAbdollahi-RoodsazSvan der BergWBDinarelloCANeteaMGFontaineTDe LucaAMorettiSRomaniLLatgeJ-Pvan de VeerdonkFL. 2014. A polysaccharide virulence factor from Aspergillus fumigatus elicits anti-inflammatory effects through induction of interleukin-1 receptor antagonist. PLoS Pathog 10:e1003936, doi:10.1371/journal.ppat.1003936
  • GuerreroCPrietoALealJA. 1988. Extracellular galactosaminogalactan from Penicillium frequentans. Microbiol Madr Spain 4:39–46.
  • HuaK-FHsuH-YChaoLKChenS-TYangW-BHsuJWongC-H. 2007. Ganoderma lucidum polysaccharides enhance CD14 endocytosis of LPS and promote TLR4 signal transduction of cytokine expression. J Cell Physiol 212:537–550, doi:10.1002/jcp.21050
  • JorgeJAKinneySGReissigJL. 1982. Purification and characterization of Neurospora crassa N-acetyl galactosaminoglycan deacetylase. Braz J Med Biol Res Rev Bras Pesqui Médicas E Biológicas Soc Bras Biofísica Al 15:29–34.
  • KarlyshevAVEverestPLintonDCawthrawSNewellDGWrenBW. 2004. The Campylobacter jejuni general glycosylation system is important for attachment to human epithelial cells and in the colonization of chicks. Microbiol Read Engl 150:1957–1964, doi:10.1099/mic.0.26721-0
  • KöseoğluVKHeissCAzadiPTopchiyEGüvenerZTLehmannTEMillerKWGomelskyM. 2015. Listeria monocytogenes exopolysaccharide: origin, structure, biosynthetic machinery and c-di-GMP-dependent regulation. Mol Microbiol 96:728–743, doi:10.1111/mmi.12966
  • LamarreCBeauRBalloyVFontaineTHoiJWSGuadagniniSBerkovaNChignardMBeauvaisALatgéJ-P. 2009. Galactofuranose attenuates cellular adhesion of Aspergillus fumigatus. Cell Microbiol 11: 1612–1623, doi:10.1111/j.1462-5822.2009.01352.x
  • LatgéJPKobayashiHDebeaupuisJPDiaquinMSarfatiJWieruszeskiJMParraEBoucharaJPFournetB. 1994. Chemical and immunological characterization of the extracellular galactomannan of Aspergillus fumigatus. Infect Immun 62:5424–5433.
  • LeclereLvan CutsemPMichielsC. 2013. Anti-cancer activities of pH- or heat-modified pectin. Pharmacol Anti-Cancer Drugs 4:128, doi:10.3389/fphar.2013.00128
  • LeeMJGravelatFNCeroneRPBaptistaSDCampoliPVChoeS-IKravtsovIVinogradovECreuzenetCLiuHBerghuisAMLatgéJ-PFillerSGFontaineTSheppardDC. 2014. Overlapping and distinct roles of Aspergillus fumigatus UDP-glucose 4-epimerases in galactose metabolism and the synthesis of galactose-containing cell wall polysaccharides. J Biol Chem 289:1243–1256, doi:10.1074/jbc.M113.522516
  • LeeMJLiuHBarkerBMSnarrBDGravelatFNAl AbdallahQGavinoCBaistrocchiSROstapskaHXiaoTRalphBSolisNVLehouxMBaptistaSDThammahongACeroneRPKaminskyjSGWGuiotM-CLatgéJ-PFontaineTVinhDCFillerSGSheppardDC. 2015. The fungal exopolysaccharide galactosaminogalactan mediates virulence by enhancing resistance to neutrophil extracellular traps. PLoS Pathog 11:e1005187, doi:10.1371/journal.ppat.1005187
  • LeeS-HKoC-IAhnGYouSKimJ-SHeuMSKimJJeeYJeonY-J. 2012. Molecular characteristics and anti-inflammatory activity of the fucoidan extracted from Ecklonia cava. Carbohydr Polym 89:599–606, doi:10.1016/j.carbpol.2012.03.056
  • Letscher-BruVCavalierAPernot-MarinoEKoenigHEyerDWallerJCandolfiE. 1998. Aspergillus galactomannan antigen detection with Platelia (R) Aspergillus: multiple positive antigenemia without Aspergillus infection. J Mycol Medicale 8:112–113.
  • LiuLLiYHNiuYBSunYGuoZJLiQLiCFengJCaoSSMeiQB. 2010. An apple oligogalactan prevents against inflammation and carcinogenesis by targeting LPS/TLR4/NF-κB pathway in a mouse model of colitis-associated colon cancer. Carcinogenesis 31: 1822–1832, doi:10.1093/carcin/bgq070
  • LoussertCSchmittCPrevostM-CBalloyVFadelEPhilippeBKauffmann-LacroixCLatgéJPBeauvaisA. 2010. In vivo biofilm composition of Aspergillus fumigatus. Cell Microbiol 12:405–410, doi:10.1111/j.1462-5822.2009.01409.x
  • MuszkietaLAimaniandaVMelladoEGribaldoSAlcàzar-FuoliLSzewczykEPrevostM-CLatgéJ-P. 2014. Deciphering the role of the chitin synthase families 1 and 2 in the in vivo and in vitro growth of Aspergillus fumigatus by multiple gene targeting deletion. Cell Microbiol 16:1784–1805, doi:10.1111/cmi.12326
  • PhilippeBIbrahim-GranetOPrévostMCGougerot-PocidaloMAPerezMSder MeerenAVLatgéJP. 2003. Killing of Aspergillus fumigatus by alveolar macrophages is mediated by reactive oxidant intermediates. Infect Immun 71:3034–3042, doi:10.1128/IAI.71.6.3034-3042.2003
  • PiccioniMMonariCKennoSPericoliniEGabrielliEPietrellaDPeritoSBistoniFKozelTRVecchiarelliA. 2013. A purified capsular polysaccharide markedly inhibits inflammatory response during endotoxic shock. Infect Immun 81:90–98, doi:10.1128/IAI.00553-12
  • PopovSVOvodovaRGOvodovYS. 2006. Effect of lemnan, pectin from Lemna minor L., and its fragments on inflammatory reaction. Phytother Res 20:403–407, doi:10.1002/ptr.1869
  • PopovSVOvodovYS. 2013. Polypotency of the immunomodulatory effect of pectins. Biochem Biokhimiia 78:823–835, doi:10.1134/S0006297913070134
  • PopovSVPopovaGYPaderinNMKovalOAOvodovaRGOvodovYS. 2007. Preventative antiinflammatory effect of potamogetonan, a pectin from the common pondweed Potamogeton natans L. Phytother Res 21:609–614, doi:10.1002/ptr.2125
  • PringleRB. 1981. Nonspecific adhesion of Bipolaris sorokiniana sporelings. Can J Plant Pathol 3:9–11, doi:10.1080/07060668109501396
  • RambachGBlumGLatgéJ-PFontaineTHeinekampTHagleitnerMJeckströmHWeigelGWürtingerPPfallerKKrappmannSLöfflerJLass-FlörlCSpethC. 2015. Identification of Aspergillus fumigatus surface components that mediate interaction of conidia and hyphae with human platelets. J Infect Dis 212:1140–1149, doi:10.1093/infdis/jiv191
  • ReissigJLGlasgowJE. 1971. Mucopolysaccharide which regulates growth in Neurospora. J Bacteriol 106:882–889.
  • RobinetPBaychelierFFontaineTPicardCDebréPVieillardVLatgéJ-PElbimC. 2014. A polysaccharide virulence factor of a human fungal pathogen induces neutrophil apoptosis via NK Cells. J Immunol 192: 5332–5342, doi:10.4049/jimmunol.1303180
  • RomaniL. 2011. Immunity to fungal infections. Nat Rev Immunol 11:275–288, doi:10.1038/nri2939
  • RuperezJAL. 1981. Extracellular galactosaminogalactan from Aspergillus parasiticus. Trans Br Mycol Soc 77: 621–625, doi:10.1016/S0007-1536(81)80111-8
  • SalmanHBergmanMDjaldettiMOrlinJBesslerH. 2008. Citrus pectin affects cytokine production by human peripheral blood mononuclear cells. Biomed Pharmacother 62:579–582, doi:10.1016/j.biopha.2008.07.058
  • SuranaNKKasperDL. 2012. The yin yang of bacterial polysaccharides: lessons learned from B. fragilis PSA. Immunol Rev 245:13–26, doi:10.1111/j.1600-065X.2011.01075.x
  • SzymanskiCMBurrDHGuerryP. 2002. Campylobacter protein glycosylation affects host cell interactions. Infect Immun 70:2242–2244, doi:10.1128/IAI.70.4.2242-2244.2002
  • TakadaHArakiYItoE. 1981. Structure of polygalactosamine produced by Aspergillus parasiticus. J Biochem (Tokyo) 89:1265–1274.
  • TakagiHKadowakiK. 1985. Purification and chemical properties of a flocculant produced by Paecilomyces. Agric Biol Chem 49:3159–3164, doi:10.1080/00021369.1985.10867250
  • VecchiarelliARetiniCPietrellaDMonariCTasciniCBeccariTKozelTR. 1995. Downregulation by cryptococcal polysaccharide of tumor necrosis factor alpha and interleukin-1 beta secretion from human monocytes. Infect Immun 63:2919–2923.
  • VuongCKocianovaSVoyichJMYaoYFischerERDeLeoFROttoM. 2004. A crucial role for exopolysaccharide modification in bacterial biofilm formation, immune evasion and virulence. J Biol Chem 279:54881–54886, doi:10.1074/jbc.M411374200
  • WhitfieldGBMarmontLSHowellPL. 2015. Enzymatic modifications of exopolysaccharides enhance bacterial persistence. Microbiotechnol Ecotoxicol Bioremed 471, 10.3389/fmicb.2015.00471
  • WuJZhangY-YGuoLLiHChenD-F. 2013. Bupleurum polysaccharides attenuates lipopolysaccharide-induced inflammation via modulating toll-like receptor 4 signaling. PLoS One 8:e78051, doi:10.1371/journal.pone.0078051
  • YeMBLimBO. 2010. Dietary pectin regulates the levels of inflammatory cytokines and immunoglobulins in interleukin-10 knockout mice. J Agric Food Chem 58: 11281–11286, doi:10.1021/jf103262s
  • YoungNMBrissonJ-RKellyJWatsonDCTessierLLanthierPHJarrellHCCadotteNMichaelFSAbergESzymanskiCM. 2002. Structure of the N-linked glycan present on multiple glycoproteins in the Gram-negative bacterium Campylobacter jejuni. J Biol Chem 277:42530–42539, doi:10.1074/jbc.M206114200

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