References
- Bendall SC , SimondsEF, QiuPet al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science332 (6030), 687–696 (2011).
- Bandura DR , BaranovVI, OrnatskyOIet al. Mass cytometry: technique for real time single cell multitarget immunoassay based on inductively coupled plasma time-of-flight mass spectrometry. Anal. Chem. 81 (16), 6813–6822 (2009).
- Cheung RK , UtzPJ. Screening: CyTOF-the next generation of cell detection. Nat. Rev. Rheumatol. 7 (9), 502–503 (2011).
- Raj A , van den BogaardP, RifkinSAet al. Imaging individual mRNA molecules using multiple singly labeled probes. Nat. Methods5, 877–879 (2008).
- Cosma A , Le GrandR. Brief introduction to mass cytometry. Med. Sci. (Paris)27 (12), 1072–1074 (2011).
- Doerr A . A flow cytometry revolution. Nat. Methods8 (7), 531 (2011).
- Janes MR , RommelC. Next-generation flow cytometry. Nat. Biotechnol. 29 (7), 602–604 (2011).
- Giesen C , WangHA, SchapiroDet al. Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry. Nat. Methods4, 417–422 (2014).
- Saadatpour A , GuoG, OrkinSHet al. Characterizing heterogeneity in leukemic cells using single-cell gene expression analysis. Genome Biol. 15 (12), 525 (2014).
- Piccirillo S , ColmanS, PotterNEet al. Genetic and functional diversity of propagating cells in glioblastoma. Stem Cell Rep. 4 (1), 7–15 (2015).
- Fu J , StoneNR, LiuLet al. Direct reprogramming of human fibroblasts toward a cardiomyocyte-like state. Stem Cell Rep. 1 (3), 235–247 (2013).
- Krishnaswamy S , SpitzerMH, MingueneauMet al. System Biology. Conditional density-based analysis of T cell signaling in single-cell data. Science346 (6,213), 1250689 (2014).
- Victor M , RichnerM, HermanstyneTOet al. Generation of human striatal neurons by microRNA-dependent direct conversion of fibroblasts. Neuron84 (2), 311–323 (2014).
- Saliba AE , WestermannAJ, GorskiSAet al. Single-cell RNA-seq: advances and future challenges. Nucleic Acids Res. 42 (14), 8, 845–860 (2014).
- Krutzik PO , NolanGP. Fluorescent cell barcoding in flow cytometry allows high-throughput drug screening and signaling profiling. Nat. Methods3 (5), 361–368 (2006).
- Krutzik PO , ClutterMR, TrejoA, NolanGP. Fluorescent cell barcoding for multiplex flow cytometry. Curr. Protoc. Cytom. 6, Unit 6.31 (2011).
- Bodenmiller B , ZunderER, FinckRet al. Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators. Nat. Biotechnol. 30 (9), 858–867 (2012).
- Lai L , OngR, LiJ, AlbaniS. A CD45-based barcoding approach to multiplex mass-cytometry (CyTOF). Cytometry A87 (4), 369–374 (2015).
- Mei HE , LeipoldMD, SchulzAR. Barcoding of live human peripheral blood mononuclear cells for multiplexed mass cytometry. J. Immunol. 194 (4), 2022–2031 (2015).
- Zunder ER , FinckR, BehbehaniGKet al. Palladium-based mass tag cell barcoding with a doublet-filtering scheme and single-cell deconvolution algorithm. Nat. Protoc. 10 (2), 316–333 (2015).
- Nassar AF , OguraH, WisnewskiAV. Impact of recent innovations in the use of mass cytometry in support of drug development. Drug Discov. Today20 (10), 1169–1175 (2015).
- Jemal M . High-throughput quantitative bioanalysis by LC/MS/MS. Biomed. Chromatogr. 14 (6), 422–429 (2000).
- Nassar AE , TalaatRE, KamelAM. The impact of recent innovations in the use of liquid chromatography-mass spectrometry in support of drug metabolism studies: are we all the way there yet?Curr. Opin. Drug Discov. Devel. 9 (1), 61–74 (2006).
- Qian F , GoelG, MengH, WangX, YouF. Systems immunology reveals markers of susceptibility to West Nile virus infection. Clin. Vaccine Immunol. 22 (1), 6–16 (2015).
- Mohanty S , JoshiSR, UedaI, WilsonJ, BlevinsTP. Prolonged proinflammatory cytokine production in monocytes modulated by interleukin 10 after influenza vaccination in older adults. J. Infect. Dis. 211 (7), 1174–1184 (2015).
- Majonis D , OrnatskyO, KinachR, WinnikMA. Curious results with palladium- and platinum-carrying polymers in mass cytometry bioassays and an unexpected application as a dead cell stain. Biomacromolecules12 (11), 3997–4010 (2011).
- Nassar AE , CarterB, LanniganJet al. The first multi-center comparative study using a novel technology mass cytometry time-of-flight mass spectrometer (CyTOF2) for high-speed acquisition of highly multi-parametric single cell data: a status report. Presented at : CYTO 2015 30th Congress of the International Society for Advancement of Cytometry. Scottish Exhibition and Conference Centre Glasgow, UK, 26–30 June 2015.