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Methodology

Determination of Favipiravir in Human Plasma using Homogeneous Liquid–Liquid Microextraction followed by HPLC/UV

, , , & ORCID Icon
Pages 205-216 | Received 04 Oct 2021, Accepted 09 Dec 2021, Published online: 10 Jan 2022

References

  • Wiersinga WJ , RhodesA, ChengAC, PeacockSJ, PrescottHC. Pathophysiology, transmission, diagnosis, and treatment of coronavirus disease 2019 (COVID-19). JAMA324(8), 782 (2020).
  • Hamed M , El-HasabM, MansourFR. Direct acting anti-hepatitis C combinations as potential COVID-19 protease inhibitors. VirusDisease.32(2), 279–285 (2021).
  • Cai Q , YangM, LiuDet al. Experimental treatment with favipiravir for COVID-19: an open-label control study. Engineering6(10), 1192–1198 (2020).
  • Ivashchenko AA , DmitrievKA, VostokovaNVet al. AVIFAVIR for treatment of patients with moderate COVID-19: interim results of a phase II/III multicenter randomized clinical trial. Clin. Infect. Dis.79(3), 531–534 (2021).
  • Agrawal U , RajuR, UdwadiaZF. Favipiravir: a new and emerging antiviral option in COVID-19. Med. J. Armed Forces India76(4), 370–376 (2020).
  • Megahed SM , HabibAA, HammadSF, KamalAH. Experimental design approach for development of spectrofluorimetric method for determination of favipiravir; a potential therapeutic agent against COVID-19 virus: application to spiked human plasma. Spectrochim. Acta Part A Mol. Biomol. Spectrosc.249, 119241 (2021).
  • Mikhail IE , ElmansiH, BelalF, EhabIbrahim A. Green micellar solvent-free HPLC and spectrofluorimetric determination of favipiravir as one of COVID-19 antiviral regimens. Microchem. J.165, 106189 (2021).
  • Hailat M , Al-AniI, HamadM, ZakareiaZ, AbuDayyih W. Development and validation of a method for quantification of favipiravir as COVID-19 management in spiked human plasma. Molecules26(13), 3789 (2021).
  • Morsy MI , NoumanEG, AbdallahYMet al. A novel LC-MS/MS method for determination of the potential antiviral candidate favipiravir for the emergency treatment of SARS-CoV-2 virus in human plasma: application to a bioequivalence study in Egyptian human volunteers. J. Pharm. Biomed. Anal.199, 114057 (2021).
  • Habler K , BrügelM, TeupserDet al. Simultaneous quantification of seven repurposed COVID-19 drugs remdesivir (plus metabolite GS-441524), chloroquine, hydroxychloroquine, lopinavir, ritonavir, favipiravir and azithromycin by a two-dimensional isotope dilution LC–MS/MS method in human serum. J. Pharm. Biomed. Anal.196, 113935 (2021).
  • Rezk MR , BadrKA, Abdel-NabyNS, AyyadMM. A novel, rapid and simple UPLC–MS/MS method for quantification of favipiravir in human plasma: application to a bioequivalence study. Biomed. Chromatogr.35(7), 1–9 (2021).
  • Eryavuz D , AbusogluS, OnmazM, HumeyraF, UnluA. Development and validation of a sensitive, fast and simple LC-MS / MS method for the quantitation of favipiravir in human serum. J. Chromatogr. B.1176, 122768 (2021).
  • Abdel-Lateef MA , OmarMA, AliR, AlmahriA, DerayeaSM. Innovative thin-layer chromatography/fluorescence detection approach for sensitive and specific determination of ledipasvir in rats' feces and pharmaceutical dosage form. J. Chromatogr. Sci.59(7), 634–641 (2021).
  • Derayea SM , Abdel-LateefMA, OmarMA, AliR. Thin-layer chromatography/fluorescence detection approach for sensitive and selective determination of hepatitis C virus antiviral (velpatasvir): application to human plasma. Luminescence35(7), 1048–1055 (2020).
  • Hammad SF , AbdallahIA, BedairA, MansourFR. Homogeneous liquid–liquid extraction as an alternative sample preparation technique for biomedical analysis. J. Sep. Sci.https://doi.org/10.1002/jssc.202100452 (2021).
  • Buarque FS , SoaresCMF, MarquesMNet al. Simultaneous concentration and chromatographic detection of water pesticides traces using aqueous two-phase system composed of tetrahydrofuran and fructose. Microchem. J.147, 303–310 (2019).
  • Rashidipour M , HeydariR, MalekiA, MohammadiE, DavariB. Salt-assisted liquid – liquid extraction coupled with reversed- phase dispersive liquid – liquid microextraction for sensitive HPLC determination of paraquat in environmental and food samples. J. Food Meas. Charact.13(1), 269–276 (2019).
  • Tu X , SunF, WuSet al. Comparison of salting-out and sugaring-out liquid–liquid extraction methods for the partition of 10-hydroxy-2-decenoic acid in royal jelly and their co-extracted protein content. J. Chromatogr. B.1073, 90–95 (2018).
  • Hammad SF , AbdallahIA, BedairA, MansourFR. Salting-out induced liquid–liquid microextraction for alogliptin benzoate determination in human plasma by HPLC/UV. BMC Chem.15(2), 1–10 (2021).
  • Hamad A , ElshahawyM, NegmA, MansourFR. Analytical methods for determination of glutathione and glutathione disulfide in pharmaceuticals and biological fluids. Rev. Anal. Chem.38(4), 20190019 (2020).
  • Abdallah IA , HammadSF, BedairA, MansourFR. A green homogeneous liquid-liquid microextraction method for spectrophotometric determination of daclatasvir in human plasma. Sustain. Chem. Pharm.22, 100498 (2021).
  • Abdallah IA , HammadSF, BedairA, MansourFR. Sugaring-out induced homogeneous liquid-liquid microextraction as an alternative mode for biological sample preparation: a comparative study. J. Sep. Sci.44(16), 3117–3125 (2021).
  • Food and Drug Administration . Bioanalytical method validation guidance for industry. U.S. Dep. Heal. Hum. Serv. Food Drug Adm.1–41 (2018).
  • Bulduk İ . HPLC-UV method for quantification of favipiravir in pharmaceutical formulations. Acta Chromatogr.33(3), 209–215 (2021).
  • Caprin B , ChartonV, RodierJ-Det al. Scrutiny of the supramolecular structure of bio-sourced fructose/glycerol/water ternary mixtures: towards green low transition temperature mixtures. J. Mol. Liq.337, 116428 (2021).
  • Wong S , ZhaoJ, CaoCet al. Just add sugar for carbohydrate induced self-assembly of curcumin. Nat. Commun.10(1), 582 (2019).
  • Serhan M , SprowlsM, JackemeyerDet al. Total iron measurement in human serum with a smartphone. Presented at: AIChE Annu. Meet. Conf. Proc.Hyatt Regency, FL, USA (2019).
  • Chattaraj KG , PaulR, PaulS. Switching of self-assembly to solvent-assisted assembly of molecular motor: unveiling the mechanisms of dynamic control on solvent exchange. Langmuir36(7), 1773–1792 (2020).
  • Mansour FR , DanielsonND. Solidification of floating organic droplet in dispersive liquid-liquid microextraction as a green analytical tool. Talanta170, 22–35 (2017).
  • Mansour FR , KhairyMA. Pharmaceutical and biomedical applications of dispersive liquid–liquid microextraction. J. Chromatogr. B.1061–1062, 382–391 (2017).
  • Mansour FR , DanielsonND. Solvent-terminated dispersive liquid-liquid microextraction: a tutorial. Anal. Chim. Acta.1016, 1–11 (2018).
  • Nadendla PR , PatchalaDA. A validated high performance liquid chromatographic method for the quantification of favipiravir by PDA detector. Int. J. Pharma Bio. Sci.11(2), 181–188 (2021).

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